Most cited biochemistry, genetics and molecular biology papers
- Verified
Multiple cathepsins promote pro-IL-1β synthesis and NLRP3-mediated IL-1β activation
Orlowski, G. M., Colbert, J. D., Sharma, S., Bogyo, M., Robertson, S. A., & Rock, K. L. (2015) · The Journal of Immunology
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 268
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Bifurcation analysis of single-cell gene expression data reveals epigenetic landscape
Marco, E., Karp, R. L., Guo, G., Robson, P., Hart, A. H., Trippa, L., & Yuan, G.-C. (2014) · Proceedings of the National Academy of Sciences
Single-cell and spatial transcriptomicsGene Regulatory Network Analysis
Cited by 268
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Replisome assembly and the direct restart of stalled replication forks
Heller, R. C., & Marians, K. J. (2006) · Nature Reviews Molecular Cell Biology
DNA Repair MechanismsBacterial Genetics and Biotechnology
Cited by 268
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Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
Thorburn, J., Horita, H., Redzic, J., Hansen, K., Frankel, A. E., & Thorburn, A. (2009) · Cell Death & Differentiation
Autophagy in Disease and TherapyCell death mechanisms and regulation
Cited by 268
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Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17- and TNF-α-induced genes in bone cells
Shen, F., Ruddy, M. J., Plamondon, P., & Gaffen, S. L. (2004) · Journal of Leukocyte Biology
Bone Metabolism and DiseasesCytokine Signaling Pathways and Interactions
Cited by 268
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Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA
Hashimoto, H., Wang, D., Horton, J. R., Zhang, X., Corces, V. G., & Cheng, X. (2017) · Molecular Cell
Genomics and Chromatin DynamicsProtein Structure and Dynamics
Cited by 268
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Global Proteome Turnover Analyses of the Yeasts S. cerevisiae and S. pombe
Christiano, R., Nagaraj, N., Fröhlich, F., & Walther, T. C. (2014) · Cell Reports
Ubiquitin and proteasome pathwaysFungal and yeast genetics research
Cited by 268
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Tumour-infiltrating FOXP3+ lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer
West, N. R., Kost, S. E., Martin, S. D., Milne, K., deLeeuw, R. J., Nelson, B. H., & Watson, P. H. (2013) · British Journal of Cancer
Breast Cancer Treatment StudiesT-cell and B-cell Immunology
Cited by 268
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PDEF, a Novel Prostate Epithelium-specific Ets Transcription Factor, Interacts with the Androgen Receptor and Activates Prostate-specific Antigen Gene Expression
Oettgen, P., Finger, E., Sun, Z., Akbarali, Y., Thamrongsak, U., Boltax, J., Grall, F., Dube, A., Weiss, A., Brown, L., et al. (2000) · Journal of Biological Chemistry
Prostate Cancer Treatment and ResearchSperm and Testicular Function
Cited by 268
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Parkinsonism-associated Protein DJ-1/Park7 Is a Major Protein Deglycase That Repairs Methylglyoxal- and Glyoxal-glycated Cysteine, Arginine, and Lysine Residues
Richarme, G., Mihoub, M., Dairou, J., Bui, L. C., Leger, T., & Lamouri, A. (2015) · Journal of Biological Chemistry
Advanced Glycation End Products researchParkinson's Disease Mechanisms and Treatments
Cited by 268
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Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin
Grossmann, T. N., Yeh, J. T.-H., Bowman, B. R., Chu, Q., Moellering, R. E., & Verdine, G. L. (2012) · Proceedings of the National Academy of Sciences
Wnt/β-catenin signaling in development and cancerChemical Synthesis and Analysis
Cited by 268
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Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation
Moon, C., Baldridge, M. T., Wallace, M. A., Burnham, C.-A. D., Virgin, H. W., & Stappenbeck, T. S. (2015) · Nature
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 268
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Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene
Fan, C.-Y., Pan, J., Chu, R., Lee, D., Kluckman, K. D., Usuda, N., Singh, I., Yeldandi, A. V., Rao, M. S., Maeda, N., et al. (1996) · Journal of Biological Chemistry
Metabolism and Genetic DisordersPeroxisome Proliferator-Activated Receptors
Cited by 268
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Circulating trimethylamine N‐oxide and the risk of cardiovascular diseases: a systematic review and meta‐analysis of 11 prospective cohort studies
Qi, J., You, T., Li, J., Pan, T., Xiang, L., Han, Y., & Zhu, L. (2018) · Journal of Cellular and Molecular Medicine
Gut microbiota and healthNutritional Studies and Diet
Cited by 268
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Virulence-related surface glycoproteins in the yeast pathogen Candida glabrata are encoded in subtelomeric clusters and subject to RAP1 - and SIR -dependent transcriptional silencing
De Las Peñas, A., Pan, S.-J., Castaño, I., Alder, J., Cregg, R., & Cormack, B. P. (2003) · Genes & Development
Fungal and yeast genetics researchGenomics and Chromatin Dynamics
Cited by 268
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Decline in Self-Renewal Factors Contributes to Aging of the Stem Cell Niche in the Drosophila Testis
Boyle, M., Wong, C., Rocha, M., & Jones, D. L. (2007) · Cell Stem Cell
Genetics, Aging, and Longevity in Model OrganismsDevelopmental Biology and Gene Regulation
Cited by 268
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Modification Defect at Anticodon Wobble Nucleotide of Mitochondrial tRNAsLeu(UUR) with Pathogenic Mutations of Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episodes
Yasukawa, T., Suzuki, T., Suzuki, T., Ueda, T., Ohta, S., & Watanabe, K. (2000) · Journal of Biological Chemistry
RNA and protein synthesis mechanismsMitochondrial Function and Pathology
Cited by 268
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Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival
Tal, R., Winter, G., Ecker, N., Klionsky, D. J., & Abeliovich, H. (2007) · Journal of Biological Chemistry
Autophagy in Disease and TherapyFungal and yeast genetics research
Cited by 268
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Wnt Signaling in Skin Development, Homeostasis, and Disease
Lim, X., & Nusse, R. (2013) · Cold Spring Harbor Perspectives in Biology
Wnt/β-catenin signaling in development and cancerHair Growth and Disorders
Cited by 268
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The AlphaFold Database of Protein Structures: A Biologist’s Guide
David, A., Islam, S., Tankhilevich, E., & Sternberg, M. J. E. (2022) · Journal of Molecular Biology
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 268
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Biological embedding of experience: a primer on epigenetics
Aristizabal, M. J., Anreiter, I., Halldorsdottir, T., Odgers, C. L., McDade, T. W., Goldenberg, A., Mostafavi, S., Kobor, M. S., Binder, E. B., Sokolowski, M. B., et al. (2020) · Proceedings of the National Academy of Sciences
Epigenetics and DNA MethylationBirth, Development, and Health
Cited by 268
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Analysis of MRI patterns aids prediction of progression in X-linked adrenoleukodystrophy
Loes, D. J., Fatemi, A., Melhem, E. R., Gupte, N., Bezman, L., Moser, H. W., & Raymond, G. V. (2003) · Neurology
Metabolism and Genetic DisordersLysosomal Storage Disorders Research
Cited by 268
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Neurofascin assembles a specialized extracellular matrix at the axon initial segment
Hedstrom, K. L., Xu, X., Ogawa, Y., Frischknecht, R., Seidenbecher, C. I., Shrager, P., & Rasband, M. N. (2007) · The Journal of Cell Biology
Ion channel regulation and functionNeuroscience and Neuropharmacology Research
Cited by 268
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Increased Frequency of De Novo Copy Number Variants in Congenital Heart Disease by Integrative Analysis of Single Nucleotide Polymorphism Array and Exome Sequence Data
Glessner, J. T., Bick, A. G., Ito, K., Homsy, J. G., Rodriguez-Murillo, L., Fromer, M., Mazaika, E., Vardarajan, B., Italia, M., Leipzig, J., et al. (2014) · Circulation Research
Genomic variations and chromosomal abnormalitiesCongenital heart defects research
Cited by 268
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