Neurofascin assembles a specialized extracellular matrix at the axon initial segment

Culturing nerve cells

Banker, G. A., & Goslin, K. (1998) · Cited by 1,290 · see citing works

Neuronal polarity: from extracellular signals to intracellular mechanisms.

Arimura, N., & Kaibuchi, K. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2056 · Cited by 655 · see citing works

Lecticans: organizers of the brain extracellular matrix

Yamaguchi, Y. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000690 · Cited by 642 · see citing works

A Common Ankyrin-G-Based Mechanism Retains KCNQ and NaVChannels at Electrically Active Domains of the Axon

Pan, Z., Kao, T., Horvath, Z., Lemos, J. C., Sul, J., Cranstoun, S. D., Bennett, V., Scherer, S. S., & Cooper, E. C. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4314-05.2006 · Cited by 586 · see citing works

AnkyrinG Is Required for Clustering of Voltage-gated Na Channels at Axon Initial Segments and for Normal Action Potential Firing

Zhou, D., Lambert, S., Malen, P. L., Carpenter, S., Boland, L. M., & Bennett, V. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.143.5.1295 · Cited by 568 · see citing works

Perineuronal nets: past and present

Celio, M. R., Spreafico, R., De Biasi, S., & Vitellaro-Zuccarello, L. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01298-3 · Cited by 497 · see citing works

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

Jenkins, S. M., & Bennett, V. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.200109026 · Cited by 446 · see citing works

Unique features of action potential initiation in cortical neurons

Naundorf, B., Wolf, F., & Volgushev, M. (2006) · Nature · doi:10.1038/nature04610 · Cited by 396 · see citing works

In vivo electroporation in the embryonic mouse central nervous system

Saito, T. (2006) · Nature Protocols · doi:10.1038/nprot.2006.276 · Cited by 378 · see citing works

Ankyrin-Based Subcellular Gradient of Neurofascin, an Immunoglobulin Family Protein, Directs GABAergic Innervation at Purkinje Axon Initial Segment

Ango, F., Cristo, G. D., Higashiyama, H., Bennett, V., Wu, P., & Huang, Z. J. (2004) · Cell · doi:10.1016/j.cell.2004.10.004 · Cited by 371 · see citing works

A Targeting Motif Involved in Sodium Channel Clustering at the Axonal Initial Segment

Garrido, J. J., Giraud, P., Carlier, E., Fernandes, F., Moussif, A., Fache, M., Debanne, D., & Dargent, B. (2003) · Science · doi:10.1126/science.1085167 · Cited by 358 · see citing works

Neurofascins Are Required to Establish Axonal Domains for Saltatory Conduction

Sherman, D. L., Tait, S., Melrose, S., Johnson, R., Zonta, B., Court, F. A., Macklin, W. B., Meek, S. E., Smith, A., Cottrell, D. F., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.10.019 · Cited by 342 · see citing works

Site of Action Potential Initiation in Layer 5 Pyramidal Neurons

Palmer, L. M., & Stuart, G. J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4812-05.2006 · Cited by 336 · see citing works

Induction of sodium channel clustering by oligodendrocytes

Kaplan, M. R., Meyer‐Franke, A., Lambert, S., Bennett, V., Duncan, I. D., Levinson, S. R., & Barres, B. A. (1997) · Nature · doi:10.1038/386724a0 · Cited by 332 · see citing works

Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier

Eshed, Y., Feinberg, K., Poliak, S., Sabanay, H., Sarig-Nadir, O., Spiegel, I., Bermingham, J. R., & Peles, E. (2005) · Neuron · doi:10.1016/j.neuron.2005.06.026 · Cited by 321 · see citing works

βIV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier

Komada, M., & Soriano, P. M. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200110003 · Cited by 291 · see citing works

A Novel Targeting Signal for Proximal Clustering of the Kv2.1 K+ Channel in Hippocampal Neurons

Seung Taik, L. I. M., Antonucci-Durgan, D. E., Scannevin, R. H., & Trimmer, J. S. (2000) · Neuron · doi:10.1016/s0896-6273(00)80902-2 · Cited by 288 · see citing works

Brevican-Deficient Mice Display Impaired Hippocampal CA1 Long-Term Potentiation but Show No Obvious Deficits in Learning and Memory

Brakebusch, C., Seidenbecher, C. I., Asztely, F., Rauch, U., Matthies, H., Meyer, H., Krug, M., Böckers, T. M., Zhou, X., Kreutz, M. R., et al. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.21.7417-7427.2002 · Cited by 264 · see citing works

Mice Deficient for Tenascin-R Display Alterations of the Extracellular Matrix and Decreased Axonal Conduction Velocities in the CNS

Weber, P., Bartsch, U., Rasband, M. N., Czaniera, R., Lang, Y., Bluethmann, H., Margolis, R. U., Levinson, S. R., Shrager, P., Montag, D., et al. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-11-04245.1999 · Cited by 247 · see citing works

Identification of a Conserved Ankyrin-binding Motif in the Family of Sodium Channel α Subunits

Lemaillet, G., Walker, B. J., & Lambert, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303327200 · Cited by 243 · see citing works

Tyrosine Phosphorylation at a Site Highly Conserved in the L1 Family of Cell Adhesion Molecules Abolishes Ankyrin Binding and Increases Lateral Mobility of Neurofascin

Garver, T. D., Ren, Q., Tuvia, S., & Bennett, V. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.3.703 · Cited by 242 · see citing works

Properties of Action-Potential Initiation in Neocortical Pyramidal Cells: Evidence From Whole Cell Axon Recordings

Shu, Y., Duque, A., Yu, Y., Haider, B., & McCormick, D. A. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00922.2006 · Cited by 221 · see citing works

Nodes of Ranvier and axon initial segments are ankyrin G–dependent domains that assemble by distinct mechanisms

Dzhashiashvili, Y., Zhang, Y., Galinska, J., Lam, I., Grumet, M., & Salzer, J. L. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200612012 · Cited by 206 · see citing works

βIV spectrin is recruited to axon initial segments and nodes of Ranvier by ankyrinG

Yang, Y., Ogawa, Y., Hedstrom, K. L., & Rasband, M. (2007) · Journal of Cell Biology · doi:10.1083/jcb.200610128 · Cited by 200 · see citing works

Voltage-gated ion channels in the axon initial segment of human cortical pyramidal cells and their relationship with chandelier cells

Inda, M. C., DeFelipe, J., & Muñoz, A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511197103 · Cited by 184 · see citing works

Ankyrin-binding proteins related to nervous system cell adhesion molecules: candidates to provide transmembrane and intercellular connections in adult brain.

Davis, J. Q., McLaughlin, T. M., & Bennett, V. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.121.1.121 · Cited by 170 · see citing works

Uncovering multiple axonal targeting pathways in hippocampal neurons

Wisco, D. R., Anderson, E., Chang, M., Norden, C., Boiko, T., Fölsch, H., & Winckler, B. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200307069 · Cited by 168 · see citing works

Spectrins and AnkyrinB Constitute a Specialized Paranodal Cytoskeleton

Ogawa, Y., Schafer, D. P., Horresh, I., Bar, V., Hales, K., Yang, Y., Susuki, K., Peles, E., Stankewich, M. C., & Rasband, M. N. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0425-06.2006 · Cited by 162 · see citing works

Glial Membranes at the Node of Ranvier Prevent Neurite Outgrowth

Huang, J. K., Phillips, G. R., Roth, A. D., Pedraza, L., Shan, W., Belkaïd, W., Mi, S., Svenningsen, Å. F., Florens, L. A., Yates, J. R., et al. (2005) · Science · doi:10.1126/science.1118313 · Cited by 160 · see citing works

Relative Contributions of Axonal and Somatic Na Channels to Action Potential Initiation in Cerebellar Purkinje Neurons

Khaliq, Z. M., & Raman, I. M. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4664-05.2006 · Cited by 157 · see citing works

βIV Spectrins Are Essential for Membrane Stability and the Molecular Organization of Nodes of Ranvier

Yang, Y., Lacas-Gervais, S., Morest, D., Solimena, M., & Rasband, M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2125-04.2004 · Cited by 153 · see citing works

Does Paranode Formation and Maintenance Require Partitioning of Neurofascin 155 into Lipid Rafts?

Schafer, D. P., Bansal, R., Hedstrom, K. L., Pfeiffer, S., & Rasband, M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5427-03.2004 · Cited by 146 · see citing works

Restriction of 480/270-kD Ankyrin G to Axon Proximal Segments Requires Multiple Ankyrin G-specific Domains

Zhang, X., & Bennett, V. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.6.1571 · Cited by 132 · see citing works

Brevican-containing perineuronal nets of extracellular matrix in dissociated hippocampal primary cultures

John, N., Krügel, H., Frischknecht, R., Smalla, K.-H., Schultz, C., Kreutz, M. R., Gundelfinger, E. D., & Seidenbecher, C. I. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2006.01.011 · Cited by 122 · cited 3× · see citing works

An evolutionarily conserved dileucine motif in Shal K+ channels mediates dendritic targeting

Rivera, J. F., Ahmad, S., Quick, M. W., Liman, E. R., & Arnold, D. B. (2003) · Nature Neuroscience · doi:10.1038/nn1020 · Cited by 119 · see citing works

Ankyrin-Dependent and -Independent Mechanisms Orchestrate Axonal Compartmentalization of L1 Family Members Neurofascin and L1/Neuron–Glia Cell Adhesion Molecule

Boiko, T., Vakulenko, M., Ewers, H., Yap, C. C., Norden, C., & Winckler, B. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4302-06.2007 · Cited by 112 · see citing works

Secreted gliomedin is a perinodal matrix component of peripheral nerves

Eshed, Y., Feinberg, K., Carey, D. J., & Peles, E. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200612139 · Cited by 103 · see citing works

Rapid method for culturing embryonic neuron–glial cell cocultures

Svenningsen, Å. F., Shan, W., Colman, D., & Pedraza, L. (2003) · Journal of Neuroscience Research · doi:10.1002/jnr.10610 · Cited by 91 · see citing works

The Role of the Ankyrin-Binding Protein NrCAM in Node of Ranvier Formation

Custer, A., Kazarinova-Noyes, K., Sakurai, T., Xu, X.-R., Simon, W., Grumet, M., & Shrager, P. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-31-10032.2003 · Cited by 83 · see citing works

Intrinsic and extrinsic determinants of ion channel localization in neurons

Hedstrom, K. L., & Rasband, M. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04001.x · Cited by 67 · see citing works

Glial regulation of the axonal membrane at nodes of Ranvier

Schafer, D. P., & Rasband, M. N. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.08.003 · Cited by 59 · see citing works

Dependence of axon initial segment formation on Na+ channel expression

Xu, X., & Shrager, P. G. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20378 · Cited by 58 · see citing works

Differential expression of proteoglycans at central and peripheral nodes of Ranvier

Melendez‐Vasquez, C. V., Carey, D. J., Zanazzi, G. J., Reizes, O., Maurel, P., & Salzer, J. L. (2005) · Glia · doi:10.1002/glia.20245 · Cited by 56 · see citing works

Coincident enrichment of phosphorylated IκBα, activated IKK, and phosphorylated p65 in the axon initial segment of neurons

Schultz, C., König, H., Turco, D. D., Politi, C., Eckert, G. P., Ghebremedhin, E., Prehn, J. H. M., Kögel, D., & Deller, T. (2006) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2006.06.008 · Cited by 52 · see citing works

Oligodendrocytes regulate formation of nodes of Ranvier via the recognition molecule OMgp

Nie, D. A., Ma, Q., Law, J. W. S., Chia, C., Dhingra, N. K., Shimoda, Y., Yang, W.-L., Gong, N., CHEN, Q.-W., Xu, G., et al. (2006) · Neuron Glia Biology · doi:10.1017/s1740925x06000251 · Cited by 29 · see citing works

The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

Fawcett, J. W., Oohashi, T., & Pizzorusso, T. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0196-3 · Cited by 589 · see citing works

Axon Physiology

Debanne, D., Campanac, E., Bialowas, A., Carlier, E., & Alcaraz, G. (2011) · Physiological Reviews · doi:10.1152/physrev.00048.2009 · Cited by 590 · see citing works

Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity

Frischknecht, R., Heine, M., Perrais, D., Seidenbecher, C. I., Choquet, D., & Gundelfinger, E. D. (2009) · Nature Neuroscience · doi:10.1038/nn.2338 · Cited by 554 · see citing works

Establishment of axon-dendrite polarity in developing neurons.

Barnes, A. P., & Polleux, F. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125536 · Cited by 523 · see citing works

Extracellular matrix of the central nervous system: from neglect to challenge

Zimmermann, D. R., & Dours-Zimmermann, M. T. (2008) · Histochemistry and Cell Biology · doi:10.1007/s00418-008-0485-9 · Cited by 465 · see citing works

The axon initial segment and the maintenance of neuronal polarity

Rasband, M. N. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2852 · Cited by 442 · see citing works

Cell-type-dependent molecular composition of the axon initial segment

Lorincz, A., & Nusser, Z. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4833-08.2008 · Cited by 382 · see citing works

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity

Hedstrom, K. L., Ogawa, Y., & Rasband, M. N. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200806112 · Cited by 371 · see citing works

The Axon Initial Segment: An Updated Viewpoint

Leterrier, C. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1922-17.2018 · Cited by 251 · see citing works

Crosstalk between glia, extracellular matrix and neurons

Song, I., & Dityatev, A. E. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.03.003 · Cited by 263 · see citing works

Nanoscale Architecture of the Axon Initial Segment Reveals an Organized and Robust Scaffold

Leterrier, C., Potier, J., Caillol, G., Debarnot, C., Boroni-Rueda, F., & Dargent, B. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.11.051 · Cited by 244 · see citing works

A Distal Axonal Cytoskeleton Forms an Intra-Axonal Boundary that Controls Axon Initial Segment Assembly

Galiano, M. R., Jha, S., Ho, T. S., Zhang, C., Ogawa, Y., Chang, K.-J., Stankewich, M. C., Mohler, P. J., & Rasband, M. N. (2012) · Cell · doi:10.1016/j.cell.2012.03.039 · Cited by 243 · see citing works

Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain

Dityatev, A. E., Seidenbecher, C. I., & Schachner, M. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.08.003 · Cited by 229 · see citing works

The Extracellular Matrix Molecule Hyaluronic Acid Regulates Hippocampal Synaptic Plasticity by Modulating Postsynaptic L-Type Ca2+ Channels

Kochlamazashvili, G., Henneberger, C., Bukalo, O., Dvoretskova, E., Senkov, O., Lievens, P. M.-J., Westenbroek, R., Engel, A. K., Catterall, W. A., Rusakov, D. A., et al. (2010) · Neuron · doi:10.1016/j.neuron.2010.05.030 · Cited by 215 · see citing works

Disruption of the Axon Initial Segment Cytoskeleton Is a New Mechanism for Neuronal Injury

Schafer, D. P., Jha, S., Liu, F., Akella, T., McCullough, L. D., & Rasband, M. N. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3376-09.2009 · Cited by 222 · see citing works

Animal models of multiple sclerosis—Potentials and limitations

Mix, E., Meyer-Rienecker, H., Hartung, H., & Zettl, U. K. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.06.005 · Cited by 210 · see citing works

MAP2 defines a pre-axonal filtering Zone to regulate KIF1- versus KIF5-Dependent cargo transport in sensory neurons

Gumy, L. F., Katrukha, E. A., Grigoriev, I., Jaarsma, D., Kapitein, L. C., Akhmanova, A., & Hoogenraad, C. C. (2017) · Neuron · doi:10.1016/j.neuron.2017.03.046 · Cited by 186 · see citing works

Three mechanisms assemble central nervous system nodes of Ranvier

Susuki, K., Chang, K.-J., Zollinger, D. R., Liu, Y., Ogawa, Y., Eshed-Eisenbach, Y., Dours-Zimmermann, M. T., Oses-Prieto, J. A., Burlingame, A. L., Seidenbecher, C. I., et al. (2013) · Neuron · doi:10.1016/j.neuron.2013.03.005 · Cited by 186 · see citing works

Axon initial segments: structure, function, and disease

Huang, C. Y., & Rasband, M. N. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13718 · Cited by 187 · see citing works

Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments

Duflocq, A., Bras, B. L., Bullier, E., Couraud, F., & Davenne, M. (2008) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2008.06.008 · Cited by 194 · see citing works

Membrane Domains Based on Ankyrin and Spectrin Associated with Cell-Cell InteractionsPreprint

Bennett, V., & Healy, J. (2009) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003012 · Cited by 191 · see citing works

The Nodes of Ranvier: Molecular Assembly and Maintenance

Rasband, M. N., & Peles, E. (2016) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020495 · Cited by 190 · see citing works

Axon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron Polarity

Jones, S. L., & Svitkina, T. (2016) · Neural Plasticity · doi:10.1155/2016/6808293 · Cited by 184 · see citing works

The axonal cytoskeleton: from organization to function

Kevenaar, J. T., & Hoogenraad, C. C. (2015) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2015.00044 · Cited by 181 · see citing works

Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G

Bréchet, A., Fache, M., Brachet, A., Ferracci, G., Baude, A., Irondelle, M., Pereira, S., Leterrier, C., & Dargent, B. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200805169 · Cited by 172 · see citing works

The nano-architecture of the axonal cytoskeleton

Leterrier, C., Dubey, P., & Roy, S. (2017) · Nature reviews. Neuroscience · doi:10.1038/nrn.2017.129 · Cited by 167 · see citing works

Mechanisms of node of Ranvier assembly

Rasband, M. N., & Peles, E. (2020) · Nature reviews. Neuroscience · doi:10.1038/s41583-020-00406-8 · Cited by 168 · see citing works

End-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segment

Leterrier, C., Vacher, H., Fache, M., d'Ortoli, S. A., Castets, F., Autillo‐Touati, A., & Dargent, B. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1018671108 · Cited by 164 · see citing works

Spectrin- and Ankyrin-Based Membrane Domains and the Evolution of Vertebrates

Bennett, V., & Lorenzo, D. N. (2013) · Current topics in membranes · doi:10.1016/b978-0-12-417027-8.00001-5 · Cited by 159 · see citing works

A Critical Role for Neurofascin in Regulating Action Potential Initiation through Maintenance of the Axon Initial Segment

Zonta, B., Desmazières, A., Rinaldi, A., Tait, S., Sherman, D. L., Nolan, M. F., & Brophy, P. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.021 · Cited by 158 · see citing works

Short- and Long-Term Plasticity at the Axon Initial Segment

Grubb, M. S., Shu, Y., Kuba, H., Rasband, M. N., Wimmer, V. C., & Bender, K. J. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4064-11.2011 · Cited by 158 · see citing works

Cell-Permeant Large Stokes Shift Dyes for Transfection-Free Multicolor Nanoscopy

Butkevich, A. N., Lukinavičius, G., D’Este, E., & Hell, S. W. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b06412 · Cited by 151 · see citing works

Molecular Microdomains in a Sensory Terminal, the Vestibular Calyx Ending

Lysakowski, A., Gaboyard-Niay, S., Calin‐Jageman, I. E., Chatlani, S., Price, S. D., & Eatock, R. A. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0521-11.2011 · Cited by 149 · see citing works

Ultrastructure of the axonal periodic scaffold reveals a braid-like organization of actin rings

Vassilopoulos, S., Gibaud, S., Jimenez, A., Caillol, G., & Leterrier, C. (2019) · Nature Communications · doi:10.1038/s41467-019-13835-6 · Cited by 143 · see citing works

The intriguing nature of dorsal root ganglion neurons: Linking structure with polarity and function

Nascimento, A. I., Mar, F. M., & Sousa, M. M. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.05.002 · Cited by 147 · see citing works

Primary Hippocampal Neurons, Which Lack Four Crucial Extracellular Matrix Molecules, Display Abnormalities of Synaptic Structure and Function and Severe Deficits in Perineuronal Net Formation

Geissler, M., Gottschling, C., Aguado, A., Rauch, U., Wetzel, C. H., Hatt, H., & Faissner, A. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.3275-12.2013 · Cited by 140 · see citing works

The role of NrCAM in neural development and disorders—Beyond a simple glue in the brain

Sakurai, T. (2011) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2011.12.002 · Cited by 143 · see citing works

Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture

Zempel, H., Dennissen, F. J. A., Kumar, Y., Luedtke, J., Biernat, J., Mandelkow, E., & Mandelkow�, E. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.784702 · Cited by 139 · see citing works

Postsynaptic Density-93 Clusters Kv1 Channels at Axon Initial Segments Independently of Caspr2

Ogawa, Y., Horresh, I., Trimmer, J. S., Bredt, D. S., Peles, E., & Rasband, M. N. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4431-07.2008 · Cited by 141 · see citing works

Functional reciprocity between Na + channel Na v 1.6 and β1 subunits in the coordinated regulation of excitability and neurite outgrowth

Brackenbury, W. J., Calhoun, J. D., Chen, C., Miyazaki, H., Nukina, N., Oyama, F., Ranscht, B., & Isom, L. L. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909434107 · Cited by 139 · see citing works

Axon Initial Segment–Associated Microglia

Baalman, K. L., Marin, M. A., Ho, T. S., Godoy, M. I., Cherian, L., Robertson, C. S., & Rasband, M. N. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.3751-14.2015 · Cited by 138 · see citing works

Converting juvenile into adult plasticity: a role for the brain's extracellular matrix

Gundelfinger, E. D., Frischknecht, R., Choquet, D., & Heine, M. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07253.x · Cited by 136 · see citing works

Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo‐axonic synapses on CA1 pyramidal cells

Panzanelli, P., Gunn, B. G., Schlatter, M. C., Benke, D., Tyagarajan, S. K., Scheiffele, P., Belelli, D., Lambert, J. J., Rudolph, U., & Fritschy, J. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.216028 · Cited by 136 · see citing works

Molecular mechanisms of node of Ranvier formation

Susuki, K., & Rasband, M. N. (2008) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2008.09.007 · Cited by 135 · see citing works

The hyaluronan and proteoglycan link proteins: Organizers of the brain extracellular matrix and key molecules for neuronal function and plasticity

Oohashi, T., Edamatsu, M., Bekku, Y., & Carulli, D. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.09.010 · Cited by 131 · see citing works

The Adhesion-GPCR BAI1 Regulates Synaptogenesis by Controlling the Recruitment of the Par3/Tiam1 Polarity Complex to Synaptic Sites

Duman, J. G., Tzeng, C. P., Tu, Y.-K., Munjal, T., Schwechter, B., Ho, T. S., & Tolias, K. F. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3978-12.2013 · Cited by 132 · see citing works

An AnkyrinG-Binding Motif Is Necessary and Sufficient for Targeting Nav1.6 Sodium Channels to Axon Initial Segments and Nodes of Ranvier

Gasser, A. S., Ho, T. S., Cheng, X., Chang, K.-J., Waxman, S. G., Rasband, M. N., & Dib‐Hajj, S. D. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5434-11.2012 · Cited by 130 · see citing works

Sorting of Dendritic and Axonal Vesicles at the Pre-axonal Exclusion Zone

Farı́as, G. G., Guardia, C. M. A., Britt, D. J., Guo, X., & Bonifacino, J. S. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.09.074 · Cited by 126 · see citing works

Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly

Jacko, M., Weyn‐Vanhentenryck, S. M., Smerdon, J. W., Yan, R., Feng, H., Williams, D. J., Pai, J. A., Xu, K., Wichterle, H., & Zhang, C. (2018) · Neuron · doi:10.1016/j.neuron.2018.01.020 · Cited by 126 · see citing works

Ankyrin protein networks in membrane formation and stabilization

Cunha, S. R., & Mohler, P. J. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00943.x · Cited by 125 · see citing works

Versican V2 Assembles the Extracellular Matrix Surrounding the Nodes of Ranvier in the CNS

Dours-Zimmermann, M. T., Maurer, K., Rauch, U., Stoffel, W., Fassler, R., & Zimmermann, D. R. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4158-08.2009 · Cited by 123 · see citing works

Bral1: its role in diffusion barrier formation and conduction velocity in the CNS

Bekku, Y., Vargová, L., Goto, Y., Vorísek, I., Dmytrenko, L., Narasaki, M., Ohtsuka, A., Fässler, R., Ninomiya, Y., Syková, E., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5598-09.2010 · Cited by 123 · see citing works

Calcineurin Signaling Mediates Activity-Dependent Relocation of the Axon Initial Segment

Evans, M. D., Sammons, R. P., Lebron, S., Dumitrescu, A. S., Watkins, T. B. K., Uebele, V. N., Renger, J. J., & Grubb, M. S. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0277-13.2013 · Cited by 120 · see citing works

Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons

Horresh, I., Poliak, S., Grant, S., Bredt, D., Rasband, M., & Peles, E. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3398-08.2008 · Cited by 116 · see citing works

The spectrin–ankyrin–4.1–adducin membrane skeleton: adapting eukaryotic cells to the demands of animal life

Baines, A. J. (2010) · PROTOPLASMA · doi:10.1007/s00709-010-0181-1 · Cited by 120 · see citing works

A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier

Ho, T. S., Zollinger, D. R., Chang, K.-J., Xu, M., Cooper, E. C., Stankewich, M. C., Bennett, V., & Rasband, M. N. (2014) · Nature Neuroscience · doi:10.1038/nn.3859 · Cited by 116 · see citing works

The functional organization and assembly of the axon initial segment

Ogawa, Y., & Rasband, M. N. (2008) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2008.08.008 · Cited by 114 · see citing works

Brevican: A key proteoglycan in the perisynaptic extracellular matrix of the brain

Frischknecht, R., & Seidenbecher, C. I. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.03.022 · Cited by 112 · see citing works

Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments

Jones, S. L., Korobova, F., & Svitkina, T. (2014) · Journal of Cell Biology · doi:10.1083/jcb.201401045 · Cited by 111 · see citing works

The axon initial segment in nervous system disease and injury

Buffington, S. A., & Rasband, M. N. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07875.x · Cited by 108 · see citing works

Mapping axon initial segment structure and function by multiplexed proximity biotinylation

Hamdan, H., Lim, B. C., Torii, T., Joshi, A. R., Koenning, M., Smith, C. L., Palmer, D. J., Ng, P., Leterrier, C., Osés-Prieto, J. A., et al. (2020) · Nature Communications · doi:10.1038/s41467-019-13658-5 · Cited by 102 · see citing works

Building and maintaining the axon initial segment

Grubb, M. S., & Burrone, J. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.04.012 · Cited by 106 · see citing works

Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS

Bekku, Y., Rauch, U., Ninomiya, Y., & Oohashi, T. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.05873.x · Cited by 104 · see citing works

Electrical Excitability of Early Neurons in the Human Cerebral Cortex during the Second Trimester of Gestation

Moore, A. R., Filipovic, R., Mo, Z., Rasband, M. N., Zečević, N., & Antic, S. D. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn206 · Cited by 101 · see citing works

Localized Myosin II Activity Regulates Assembly and Plasticity of the Axon Initial Segment

Berger, S. L., Leo‐Macías, A., Yuen, S. K., Khatri, L., Pfennig, S., Zhang, Y., Agulló-Pascual, E., Caillol, G., Zhu, M., Rothenberg, E., et al. (2018) · Neuron · doi:10.1016/j.neuron.2017.12.039 · Cited by 100 · see citing works

Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier

Brachet, A., Leterrier, C., Irondelle, M., Fache, M., Racine, V., Sibarita, J., Choquet, D., & Dargent, B. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.201003042 · Cited by 97 · see citing works

Ankyrin-G Directly Binds to Kinesin-1 to Transport Voltage-Gated Na+ Channels into Axons

Barry, J., Gu, Y., Jukkola, P. I., O’Neill, B., Gu, H. H., Mohler, P. J., Rajamani, K. T., & Gu, C. (2014) · Developmental Cell · doi:10.1016/j.devcel.2013.11.023 · Cited by 97 · see citing works

Selective Microtubule-Based Transport of Dendritic Membrane Proteins Arises in Concert with Axon Specification

Petersen, J. D., Kaech, S., & Banker, G. A. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.3779-13.2014 · Cited by 96 · see citing works

No Pasaran! Role of the axon initial segment in the regulation of protein transport and the maintenance of axonal identity

Leterrier, C., & Dargent, B. (2013) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2013.11.001 · Cited by 96 · see citing works

αII Spectrin Forms a Periodic Cytoskeleton at the Axon Initial Segment and Is Required for Nervous System Function

Huang, C. Y., Zhang, C., Ho, T. S., Osés-Prieto, J. A., Burlingame, A. L., Lalonde, J. W., Noebels, J. L., Leterrier, C., & Rasband, M. N. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.2112-17.2017 · Cited by 95 · see citing works

The Kv2.1 K+ channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ

Sarmiere, P. D., Weigle, C. M., & Tamkun, M. M. (2008) · BMC Neuroscience · doi:10.1186/1471-2202-9-112 · Cited by 94 · see citing works

Glia unglued: How signals from the extracellular matrix regulate the development of myelinating glia

Colognato, H., & Tzvetanova, I. D. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20966 · Cited by 90 · see citing works

Axon initial segment dysfunction in epilepsy

Wimmer, V. C., Reid, C. A., So, E., Berkovic, S. F., & Petrou, S. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.188417 · Cited by 93 · see citing works

Organization and maintenance of molecular domains in myelinated axons

Buttermore, E. D., Thaxton, C., & Bhat, M. A. (2013) · Journal of Neuroscience Research · doi:10.1002/jnr.23197 · Cited by 92 · see citing works

Nodes of Ranvier during development and repair in the CNS

Lubetzki, C., Sol‐Foulon, N., & Desmazières, A. (2020) · Nature Reviews Neurology · doi:10.1038/s41582-020-0375-x · Cited by 87 · see citing works

Neuro-glial interactions at the nodes of Ranvier: implication in health and diseases

Faivre‐Sarrailh, C., & Devaux, J. J. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00196 · Cited by 85 · see citing works

Neurofascin: A switch between neuronal plasticity and stability

Kriebel, M., Wuchter, J., Trinks, S., & Volkmer, H. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.01.012 · Cited by 86 · see citing works

The crosstalk of hyaluronan-based extracellular matrix and synapses

Frischknecht, R., & Seidenbecher, C. I. (2008) · Neuron Glia Biology · doi:10.1017/s1740925x09990226 · Cited by 84 · see citing works

Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM

Tai, Y., Gallo, N. B., Wang, M., Yu, J.-R., & Aelst, L. V. (2019) · Neuron · doi:10.1016/j.neuron.2019.02.009 · Cited by 85 · see citing works

GoFDR: A sequence alignment based method for predicting protein functions

Gong, Q., Ning, W., & Tian, W. (2015) · Methods · doi:10.1016/j.ymeth.2015.08.009 · Cited by 84 · see citing works

Structural basis of diverse membrane target recognitions by ankyrins

Wang, C., Wei, Z., Chen, K., Ye, F., Yu, C., Bennett, V., & Zhang, M. (2014) · eLife · doi:10.7554/elife.04353 · Cited by 80 · see citing works

Acceleration of conduction velocity linked to clustering of nodal components precedes myelination

Freeman, S. A., Desmazières, A., Simonnet, J., Gatta, M., Pfeiffer, F., Aigrot, M. S., Rappeneau, Q., Guerreiro, S., Michel, P. P., Yanagawa, Y., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1419099112 · Cited by 80 · see citing works

The Axon Initial Segment, 50 Years Later

Leterrier, C. (2015) · Current topics in membranes · doi:10.1016/bs.ctm.2015.10.005 · Cited by 79 · see citing works

Cysteine 70 of Ankyrin-G Is S-Palmitoylated and Is Required for Function of Ankyrin-G in Membrane Domain Assembly

He, M., Jenkins, P. M., & Bennett, V. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.417501 · Cited by 78 · see citing works

Cooperative Interactions between 480 kDa Ankyrin-G and EB Proteins Assemble the Axon Initial Segment

Freal, A., Fassier, C., Bras, B. L., Bullier, E., Gois, S. D., Hazan, J., Hoogenraad, C. C., & Couraud, F. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.3219-15.2016 · Cited by 77 · see citing works

Voltage-gated sodium channel organization in neurons: Protein interactions and trafficking pathways

Leterrier, C., Brachet, A., Fache, M., & Dargent, B. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.08.079 · Cited by 75 · see citing works

Feedback-Driven Assembly of the Axon Initial Segment

Freal, A., Rai, D., Tas, R. P., Pan, X., Katrukha, E. A., van de Willige, D., Stucchi, R., Aher, A., Yang, C., Altelaar, M. A. F., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.07.029 · Cited by 74 · see citing works

Activity-Dependent and Activity-Independent Development of the Axon Initial Segment

Kuba, H., Adachi, R., & Ohmori, H. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.4357-13.2014 · Cited by 73 · see citing works

Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment

Alpizar, S. A., Baker, A. L., Gulledge, A. T., & Hoppa, M. B. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00001 · Cited by 72 · see citing works

Genetic disruption of ankyrin-G in adult mouse forebrain causes cortical synapse alteration and behavior reminiscent of bipolar disorder

Zhu, S., Cordner, Z. A., Xiong, J., Chiu, C.-T., Artola, A., Zuo, Y., Nelson, A. D., Kim, T.-Y., Zaika, N., Woolums, B. M., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1700689114 · Cited by 71 · see citing works

The Cell Adhesion Molecule Neurofascin Stabilizes Axo-axonic GABAergic Terminals at the Axon Initial Segment

Kriebel, M., Metzger, J., Trinks, S., Chugh, D., Harvey, R. J., Harvey, K., & Volkmer, H. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.212191 · Cited by 70 · see citing works

Pinceau Organization in the Cerebellum Requires Distinct Functions of Neurofascin in Purkinje and Basket Neurons during Postnatal Development

Buttermore, E. D., Piochon, C., Wallace, M. L., Philpot, B. D., Hansel, C., & Bhat, M. A. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5602-11.2012 · Cited by 68 · see citing works

Diffusion Barriers, Mechanical Forces, and the Biophysics of Phagocytosis

Ostrowski, P. P., Grinstein, S., & Freeman, S. A. (2016) · Developmental Cell · doi:10.1016/j.devcel.2016.06.023 · Cited by 69 · see citing works

Polarized localization of voltage-gated Na + channels is regulated by concerted FGF13 and FGF14 action

Pablo, J. L., Wang, C., Presby, M. M., & Pitt, G. S. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1521194113 · Cited by 67 · see citing works

Ankyrin G Membrane Partners Drive the Establishment and Maintenance of the Axon Initial Segment

Leterrier, C., Clerc, N., Boroni-Rueda, F., Montersino, A., Dargent, B., & Castets, F. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00006 · Cited by 67 · see citing works

FGF14 Localization and Organization of the Axon Initial Segment

Xiao, M.-L., Bosch, M. K., Nerbonne, J., & Ornitz, D. (2013) · Molecular and cellular neurosciences · doi:10.1016/j.mcn.2013.07.008 · Cited by 69 · see citing works

The role of Gpi-anchored axonal glycoproteins in neural development and neurological disorders.

Gennarini, G., Bizzoca, A., Picocci, S., Puzzo, D., Corsi, P., & Furley, A. (2017) · Molecular and cellular neurosciences · doi:10.1016/j.mcn.2016.11.006 · Cited by 59 · see citing works

Anti-pan-neurofascin antibodies induce subclass-related complement activation and nodo-paranodal damage

Appeltshauser, L., Junghof, H., Messinger, J., Linke, J., Haarmann, A., Ayzenberg, I., Baka, P., Dorst, J., Fisse, A. L., Grüter, T., et al. (2022) · Brain · doi:10.1093/brain/awac418 · Cited by 63 · see citing works

βIV Spectrinopathies Cause Profound Intellectual Disability, Congenital Hypotonia, and Motor Axonal Neuropathy

Wang, C.-C., Ortiz-Gonzalez, X. R., Yum, S. W., Gill, S. M., White, A. L., Kelter, E., Seaver, L. H., Lee, S., Wiley, G. B., Gaffney, P. M., et al. (2018) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2018.04.012 · Cited by 63 · see citing works

The Axon Initial Segment is the Dominant Contributor to the Neuron's Extracellular Electrical Potential Landscape

Bakkum, D. J., Obien, M. E. J., Radivojević, M., Jäckel, D., Frey, U., Takahashi, H., & Hierlemann, A. R. (2018) · Advanced Biosystems · doi:10.1002/adbi.201800308 · Cited by 68 · see citing works

Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment

Alpizar, S. A., Baker, A. L., Gulledge, A. T., & Hoppa, M. B. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00001 · Cited by 72 · see citing works

A Critical Role for Neurofascin in Regulating Action Potential Initiation through Maintenance of the Axon Initial Segment

Zonta, B., Desmazières, A., Rinaldi, A., Tait, S., Sherman, D. L., Nolan, M. F., & Brophy, P. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.021 · Cited by 158 · see citing works

Nodes of Ranvier and axon initial segments are ankyrin G–dependent domains that assemble by distinct mechanisms

Dzhashiashvili, Y., Zhang, Y., Galinska, J., Lam, I., Grumet, M., & Salzer, J. L. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200612012 · Cited by 206 · see citing works

AIS neurofascin'd to matrix

Leslie, M. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.1785iti2

Crystal structure of Ankyrin-G in complex with a fragment of Neurofascin reveals binding mechanisms required for integrity of the axon initial segment

He, L., Jiang, W., Li, J., & Wang, C. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102272 · Cited by 14 · see citing works