Replisome assembly and the direct restart of stalled replication forks
Abstract
Failure to reactivate either stalled or collapsed replication forks is a source of genomic instability in both prokaryotes and eukaryotes. In prokaryotes, dedicated fork repair systems that involve both recombination and replication proteins have been identified genetically and characterized biochemically. Replication conflicts are solved through several pathways, some of which require recombination and some of which operate directly at the stalled fork. Some recent biochemical observations support models of direct fork repair in which the removal of the blocking template lesion is not always required for replication restart.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
DSBs can be generated at stalled forks that contain strand termini of double-stranded/single-stranded DNA (ds-ssDNA) junctions, mostly from Okazaki fragments.
“DSBs can be generated at stalled forks [59,62-64] that contain strand termini of double-stranded/single-stranded DNA (ds-ssDNA) junctions, mostly from Okazaki fragments.”
From Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A (2009) · cites this paper as [63]
Cites
Biochemistry of homologous recombination in Escherichia coli
Kowalczykowski, S. C., Dixon, D. A., Eggleston, A. K., Lauder, S., & Rehrauer, W. M. (1994) · Microbiological Reviews · doi:10.1128/mr.58.3.401-465.1994 · Cited by 1,250 · see citing works
Rupp, W. D., & Howard-flanders, P. (1968) · Journal of Molecular Biology · doi:10.1016/0022-2836(68)90445-2 · Cited by 1,093 · see citing works
The importance of repairing stalled replication forks
Cox, M. M., Goodman, M. F., Kreuzer, K. N., Sherratt, D. J., Sandler, S. J., & Marians, K. J. (2000) · Nature · doi:10.1038/35003501 · Cited by 1,044 · see citing works
Self-citationRecombinational Repair of DNA Damage in Escherichia coli and Bacteriophage λ
Kuzminov, A. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.4.751-813.1999 · Cited by 897 · see citing works
The dnaA protein complex with the E. coli chromosomal replication origin (oriC) and other DNA sites
Fuller, R. S., Funnell, B. E., & Kornberg, A. (1984) · Cell · doi:10.1016/0092-8674(84)90284-8 · Cited by 683 · see citing works
Exchanges between DNA strands in ultraviolet-irradiated Escherichia coli
Rupp, W. D., Wilde, C. E., Reno, D., & Howard-Flanders, P. (1971) · Journal of Molecular Biology · doi:10.1016/0022-2836(71)90204-x · Cited by 577 · see citing works
Lopes, M., Foiani, M., & Sogo, J. M. (2006) · Molecular Cell · doi:10.1016/j.molcel.2005.11.015 · Cited by 563 · see citing works
Crosstalk between SUMO and Ubiquitin on PCNA Is Mediated by Recruitment of the Helicase Srs2p
Papouli, E., Chen, S., Davies, A. A., Huttner, D., Krejčí, L., Sung, P., & Ulrich, H. D. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.06.001 · Cited by 522 · see citing works
The Escherichia coli dnaB replication protein is a DNA helicase.
LeBowitz, J. H., & McMacken, R. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38564-2 · Cited by 504 · see citing works
Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis
Tang, M., Pham, P., Shen, X., Taylor, J.-S., O'Donnell, M., Woodgate, R., & Goodman, M. F. (2000) · Nature · doi:10.1038/35010020 · Cited by 443 · see citing works
Postreplication repair of DNA in ultraviolet-irradiated mammalian cells
Lehmann, A. R. (1972) · Journal of Molecular Biology · doi:10.1016/0022-2836(72)90418-4 · Cited by 437 · see citing works
Okazaki, R., Okazaki, T., SAKABE, K., Sugimoto, K., & Sugino, A. (1968) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.59.2.598 · Cited by 435 · see citing works
Recombinational repair and restart of damaged replication forks
McGlynn, P., & Lloyd, R. G. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm951 · Cited by 397 · see citing works
Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae
Myung, K., Chen, C. C., & Kolodner, R. (2001) · Nature · doi:10.1038/35082608 · Cited by 369 · see citing works
Kim, S., Dallmann, H. G., McHenry, C. S., & Marians, K. J. (1996) · Cell · doi:10.1016/s0092-8674(00)81039-9 · Cited by 354 · see citing works
Self-citationMultiple pathways process stalled replication forks
Michel, B., Grompone, G., Florès, M.-J., & Bidnenko, V. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401586101 · Cited by 322 · see citing works
Helicase motifs: the engine that powers DNA unwinding
Hall, M. C., & Matson, S. W. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01659.x · Cited by 320 · see citing works
Replication fork reactivation downstream of a blocked nascent leading strand
Heller, R. C., & Marians, K. J. (2006) · Nature · doi:10.1038/nature04329 · Cited by 318 · see citing works
Self-citationDNA helicases: Enzymes with essential roles in all aspects of DNA metabolism
Matson, S. W., Bean, D. W., & George, J. W. (1994) · BioEssays · doi:10.1002/bies.950160103 · Cited by 293 · see citing works
Prakash, L. (1981) · Molecular and General Genetics MGG · doi:10.1007/bf00352525 · Cited by 291 · see citing works
McGlynn, P., & Lloyd, R. (2000) · Cell · doi:10.1016/s0092-8674(00)80621-2 · Cited by 288 · see citing works
UvrD helicase, unlike Rep helicase, dismantles RecA nucleoprotein filaments in Escherichia coli
Veaute, X., Delmas, S., Selva, M., Jeusset, J., Cam, É. L., Matić, I., Fabre, F., & Petit, M. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600485 · Cited by 263 · see citing works
Lambert, S., Watson, A. T., Sheedy, D. M., Martin, B. R., & Carr, A. M. (2005) · Cell · doi:10.1016/j.cell.2005.03.022 · Cited by 261 · see citing works
Baker, T. A., Sekimizu, K., Funnell, B. E., & Kornberg, A. (1986) · Cell · doi:10.1016/0092-8674(86)90537-4 · Cited by 252 · see citing works
DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae
Broomfield, S., Hryciw, T., & Xiao, W. (2001) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(01)00091-x · Cited by 243 · see citing works
Kaguni, J. M., & Kornberg, A. (1984) · Cell · doi:10.1016/0092-8674(84)90539-7 · Cited by 240 · see citing works
Uncoupling of Leading- and Lagging-Strand DNA Replication During Lesion Bypass in Vivo
Pagès, V., & Fuchs, R. P. (2003) · Science · doi:10.1126/science.1083964 · Cited by 221 · see citing works
Role of PriA in Replication Fork Reactivation in Escherichia coli
Sandler, S. J., & Marians, K. J. (2000) · Journal of Bacteriology · doi:10.1128/jb.182.1.9-13.2000 · Cited by 213 · see citing works
Self-citationRecA-Dependent Recovery of Arrested DNA Replication Forks
Courcelle, J., & Hanawalt, P. C. (2003) · Annual Review of Genetics · doi:10.1146/annurev.genet.37.110801.142616 · Cited by 210 · see citing works
Ganesan, A. K. (1974) · Journal of Molecular Biology · doi:10.1016/0022-2836(74)90563-4 · Cited by 209 · see citing works
Lane, H. E. D., & Denhardt, D. T. (1975) · Journal of Molecular Biology · doi:10.1016/s0022-2836(75)80025-8 · Cited by 201 · see citing works
Fang, L., Davey, M. J., & O’Donnell, M. E. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80205-1 · Cited by 198 · see citing works
The DNA replication protein PriA and the recombination protein RecG bind D-loops
McGlynn, P., Al-Deib, A. A., Liu, J., Marians, K. J., & Lloyd, R. G. (1997) · Journal of Molecular Biology · doi:10.1006/jmbi.1997.1120 · Cited by 198 · see citing works
Self-citationPriA-directed replication fork restart in Escherichia coli
Marians, K. J. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01565-6 · Cited by 180 · see citing works
Self-citationYuzhakov, A., Turner, J., & O'Donnell, M. (1996) · Cell · doi:10.1016/s0092-8674(00)80163-4 · Cited by 180 · see citing works
Kogoma, T., Cadwell, G. W., Barnard, K. G., & Asai, T. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.5.1258-1264.1996 · Cited by 180 · see citing works
Interaction of Escherichia coli dnaB and dnaC(D) gene products in vitro.
Wickner, S., & Hurwitz, J. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.3.921 · Cited by 176 · see citing works
Conversion of ϕX174 Viral DNA to Double-Stranded Form by Purified Escherichia coli Proteins
Wickner, S., & Hurwitz, J. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.10.4120 · Cited by 173 · see citing works
Sandler, S. J., Samra, H. S., & Clark, A. J. (1996) · Genetics · doi:10.1093/genetics/143.1.5 · Cited by 173 · see citing works
Multiple Genetic Pathways for Restarting DNA Replication Forks in Escherichia coli K-12
Sandler, S. J. (2000) · Genetics · doi:10.1093/genetics/155.2.487 · Cited by 172 · see citing works
PriA helicase and SSB interact physically and functionally
Cadman, C. J. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh980 · Cited by 171 · see citing works
Whitby, M. C., Ryder, L., & Lloyd, R. G. (1993) · Cell · doi:10.1016/0092-8674(93)80075-p · Cited by 165 · see citing works
Lawrence, C. W., & Christensen, R. B. (1979) · Journal of Bacteriology · doi:10.1128/jb.139.3.866-876.1979 · Cited by 161 · see citing works
Inactivation of the Escherichia coli priA DNA replication protein induces the SOS response
Nurse, P., Zavitz, K. H., & Marians, K. J. (1991) · Journal of Bacteriology · doi:10.1128/jb.173.21.6686-6693.1991 · Cited by 159 · see citing works
Self-citationBaker, T. A., Funnell, B. E., & Kornberg, A. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48326-3 · Cited by 159 · see citing works
Mok, M., & Marians, K. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)49304-0 · Cited by 156 · see citing works
Self-citationFlores, M. J., Sanchez, N., & Michel, B. (2005) · Molecular Microbiology · doi:10.1111/j.1365-2958.2005.04753.x · Cited by 152 · see citing works
Heller, R. C., & Marians, K. J. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.01.019 · Cited by 152 · see citing works
Self-citationIyer, V. N., & Rupp, W. D. (1971) · Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · doi:10.1016/0005-2787(71)90551-x · Cited by 150 · see citing works
Tougu, K., Peng, H., & Marians, K. J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41829-1 · Cited by 149 · see citing works
Self-citationCourcelle, J., Crowley, D. J., & Hanawalt, P. C. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.3.916-922.1999 · Cited by 141 · see citing works
Genome stability and the processing of damaged replication forks by RecG
McGlynn, P., & Lloyd, R. G. (2002) · Trends in Genetics · doi:10.1016/s0168-9525(02)02720-8 · Cited by 141 · see citing works
Higuchi, K., Katayama, T., Iwai, S., Hidaka, M., Horiuchi, T., & Maki, H. (2003) · Genes to Cells · doi:10.1046/j.1365-2443.2003.00646.x · Cited by 140 · see citing works
Schekman, R. W., Weiner, J. H., Weiner, A. L., & Kornberg, A. (1975) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)41132-0 · Cited by 139 · see citing works
Replication fork assembly at recombination intermediates is required for bacterial growth
Liu, J., Xu, L., Sandler, S. J., & Marians, K. J. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3552 · Cited by 130 · see citing works
Self-citationLee, E. H., & Kornberg, A. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.8.3029 · Cited by 129 · see citing works
Ogawa, T., Hirose, S., Okazaki, T., & Okazaki, R. (1977) · Journal of Molecular Biology · doi:10.1016/s0022-2836(77)80160-5 · Cited by 129 · see citing works
Gregg, A. V., McGlynn, P., Jaktaji, R. P., & Lloyd, R. G. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00455-0 · Cited by 126 · see citing works
Escherichia coli PriA protein is essential for inducible and constitutive stable DNA replication.
Masai, H., Asai, T., Kubota, Y., Arai, K., & Kogoma, T. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06868.x · Cited by 122 · see citing works
Functional Uncoupling of Twin Polymerases
McInerney, P., & O’Donnell, M. E. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m401649200 · Cited by 118 · see citing works
PriA-directed Assembly of a Primosome on D Loop DNA
Liu, J., & Marians, K. J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.35.25033 · Cited by 117 · see citing works
Self-citationThe nonmutagenic repair of broken replication forks via recombination
Cox, M. M. (2002) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/s0027-5107(02)00256-7 · Cited by 112 · see citing works
Replication fork collapse at replication terminator sequences
Bidnenko, V., Ehrlich, S., & Michel, B. (2002) · EMBO Journal · doi:10.1093/emboj/cdf369 · Cited by 112 · see citing works
Svoboda, D. L., & Vos, J. M. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.26.11975 · Cited by 111 · see citing works
PriA Mediates DNA Replication Pathway Choice at Recombination Intermediates
Xu, L., & Marians, K. J. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00061-3 · Cited by 111 · see citing works
Self-citationGaps in DNA synthesized by ultraviolet light-irradiated WI38 human cells
Meneghini, R. (1976) · Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · doi:10.1016/0005-2787(76)90006-x · Cited by 103 · see citing works
The Ordered Assembly of the φX174-type Primosome
Ng, J. Y., & Marians, K. J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.26.15642 · Cited by 103 · see citing works
Self-citationCordeiro‐Stone, M., Makhov, A. M., Zaritskaya, L., & Griffith, J. D. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1999.2847 · Cited by 102 · see citing works
Two Modes of PriA Binding to DNA
Nurse, P., Liu, J., & Marians, K. J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.35.25026 · Cited by 101 · see citing works
Self-citationModulation of recombination and DNA repair by the RecG and PriA helicases of Escherichia coli K-12
Al-Deib, A. A., Mahdi, A. A., & Lloyd, R. G. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.23.6782-6789.1996 · Cited by 98 · see citing works
Duplex opening by primosome protein PriA for replisome assembly on a recombination intermediate
Jones, J. M., & Nakai, H. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1999.2783 · Cited by 95 · see citing works
Sandler, S. J., Marians, K. J., Zavitz, K. H., Coutu, J., Parent, M. A., & Clark, A. J. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01576.x · Cited by 95 · see citing works
Self-citationSuppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae
Zhang, C., Roberts, T. M., Yang, J., Desai, R., & Brown, G. W. (2005) · DNA repair · doi:10.1016/j.dnarep.2005.10.010 · Cited by 93 · see citing works
Heller, R. C., & Marians, K. J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m507224200 · Cited by 93 · see citing works
Self-citationCromie, G. A., & Leach, D. R. F. (2000) · Molecular Cell · doi:10.1016/s1097-2765(05)00095-x · Cited by 92 · see citing works
DNA Repeat Rearrangements Mediated by DnaK-Dependent Replication Fork Repair
Goldfless, S. J., Morag, A. S., Belisle, K. A., Sutera, V. A., & Lovett, S. T. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.01.025 · Cited by 90 · see citing works
INTERPLAY BETWEEN DNA REPLICATION AND RECOMBINATION IN PROKARYOTES
Kreuzer, K. N. (2005) · Annual Review of Microbiology · doi:10.1146/annurev.micro.59.030804.121255 · Cited by 90 · see citing works
Yancey-Wrona, J. E., & Matson, S. W. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.24.6713 · Cited by 86 · see citing works
The Ordered Assembly of the φX174-type Primosome
Liu, J., Nurse, P., & Marians, K. J. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.26.15656 · Cited by 80 · see citing works
Self-citationError-free Recombinational Repair Predominates over Mutagenic Translesion Replication in E. coli
Berdichevsky, A., Izhar, L., & Livneh, Z. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00679-2 · Cited by 70 · see citing works
Mahdi, A. A., Buckman, C., Harris, L., & Lloyd, R. G. (2006) · Genes & Development · doi:10.1101/gad.382306 · Cited by 60 · see citing works
PriA mutations that affect PriA–PriC function during replication restart
Sandler, S. J., McCool, J. D., Thien, T., & Johansen, R. U. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02547.x · Cited by 57 · see citing works
Jones, J. M., & Nakai, H. (2001) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.4930 · Cited by 55 · see citing works
McCool, J. D., & Sandler, S. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.121007698 · Cited by 55 · see citing works
A Critical Role of the 3′ Terminus of Nascent DNA Chains in Recognition of Stalled Replication Forks
Mizukoshi, T., Tanaka, T., Arai, K., Kohda, D., & Masai, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.c300285200 · Cited by 54 · see citing works
Stabilization of a Stalled Replication Fork by Concerted Actions of Two Helicases
Tanaka, T., & Masai, H. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m510979200 · Cited by 54 · see citing works
PriA supports two distinct pathways for replication restart in UV‐irradiated Escherichia coli cells
Jaktaji, R. P., & Lloyd, R. G. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03357.x · Cited by 51 · see citing works
Donaldson, J. R., Courcelle, C. T., & Courcelle, J. (2004) · Genetics · doi:10.1534/genetics.166.4.1631 · Cited by 49 · see citing works
DNA synthesis in sensitive and resistant mutants of Escherichia coli B after ultraviolet irradiation
Smith, K. C. (1969) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(69)90065-7 · Cited by 47 · see citing works
Sandler, S. J. (2005) · Genetics · doi:10.1534/genetics.104.036962 · Cited by 44 · see citing works
Discontinuous or semi‐discontinuous DNA replication in Escherichia coli?
Wang, T. V. (2005) · BioEssays · doi:10.1002/bies.20233 · Cited by 43 · see citing works
recA-Dependent DNA repair in UV-irradiated Escherichia coli
Smith, K. C., Wang, T. V., & Sharma, R. C. (1987) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/1011-1344(87)80002-7 · Cited by 42 · see citing works
Thomas, D. C., Veaute, X., Kunkel, T. A., & Fuchs, R. P. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.16.7752 · Cited by 40 · see citing works
A dnaT Mutant With Phenotypes Similar to Those of a priA2::kan Mutant in Escherichia coli K-12
McCool, J. D., Ford, C. C., & Sandler, S. J. (2004) · Genetics · doi:10.1534/genetics.103.025296 · Cited by 40 · see citing works
Crystal Structure of PriB, a Component of the Escherichia coli Replication Restart Primosome
Lopper, M. E., Holton, J. M., & Keck, J. L. (2004) · Structure · doi:10.1016/j.str.2004.09.004 · Cited by 39 · see citing works
Requirement for RecFOR‐mediated recombination in priA mutant
Grompone, G., Sanchez, N., Ehrlich, S. D., & Michel, B. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.03997.x · Cited by 38 · see citing works
Shioi, S., Ose, T., Maenaka, K., Shiroishi, M., Abe, Y., Kohda, D., Katayama, T., & Ueda, T. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.11.104 · Cited by 33 · see citing works
Thomas, D. C., Veaute, X., Fuchs, R. P., & Kunkel, T. A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.36.21226 · Cited by 27 · see citing works
A novel dnaC mutation that suppresses priB rep mutant phenotypes in Escherichia coli K‐12
Boonsombat, R., Yeh, S., Milne, A., & Sandler, S. J. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05147.x · Cited by 18 · see citing works
Wang, T. V., & Smith, K. C. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(89)80020-8 · Cited by 17 · see citing works
Harinarayanan, R., & Gowrishankar, J. (2004) · Genetics · doi:10.1534/genetics.166.3.1165 · Cited by 13 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A., & Liu, D. R. (2016) · Nature · doi:10.1038/nature17946 · Cited by 5,437 · see citing works
DNA double-strand break repair-pathway choice in somatic mammalian cells
Scully, R., Panday, A., Elango, R., & Willis, N. A. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0152-0 · Cited by 1,445 · see citing works
Homologous recombination in DNA repair and DNA damage tolerance
Li, X., & Heyer, W. (2008) · Cell Research · doi:10.1038/cr.2008.1 · Cited by 1,203 · see citing works
Petermann, E., Orta, M. L., Issaeva, N., Schultz, N., & Helleday, T. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.01.021 · Cited by 815 · see citing works
Genome instability: a mechanistic view of its causes and consequences
Aguilera, A., & Gómez‐González, B. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2268 · Cited by 806 · see citing works
PARP is activated at stalled forks to mediate Mre11‐dependent replication restart and recombination
Bryant, H. E., Petermann, E., Schultz, N., Jemth, A., Loseva, O., Issaeva, N., Johansson, F., Fernandez, S., McGlynn, P., & Helleday, T. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.206 · Cited by 593 · see citing works
RecBCD Enzyme and the Repair of Double-Stranded DNA Breaks
Dillingham, M. S., & Kowalczykowski, S. C. (2008) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00020-08 · Cited by 586 · see citing works
Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis
Hashimoto, Y., Chaudhuri, A. R., Lopes, M., & Costanzo, V. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1927 · Cited by 537 · see citing works
RecQ helicases: multifunctional genome caretakers
Chu, W.-K., & Hickson, I. (2009) · Nature Reviews. Cancer · doi:10.1038/nrc2682 · Cited by 470 · see citing works
Quinolones: Action and Resistance Updated
Drlica, K., Hiasa, H., Kerns, R. J., Malik, M., MUSTAEV, A. A., & Zhao, X. (2009) · Current Topics in Medicinal Chemistry · doi:10.2174/156802609789630947 · Cited by 377 · see citing works
Pathways of mammalian replication fork restart
Petermann, E., & Helleday, T. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2974 · Cited by 340 · see citing works
The Mcm Complex: Unwinding the Mechanism of a Replicative Helicase
Bochman, M. L., & Schwacha, A. (2009) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00019-09 · Cited by 330 · see citing works
Repriming of DNA synthesis at stalled replication forks by human PrimPol
Mouron, S. A., Rodríguez‐Acebes, S., Martínez-Jiménez, M. I., García-Gómez, S., Chocrón, S., Blanco, L., & Méndez, J. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2719 · Cited by 322 · see citing works
Rescuing Stalled or Damaged Replication ForksPreprint
Yeeles, J. T. P., Poli, J., Marians, K. J., & Pasero, P. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012815 · Cited by 253 · see citing works
Self-citationCohesin acetylation speeds the replication fork
Terret, M., Sherwood, R., Rahman, S., Qin, J., & Jallepalli, P. V. (2009) · Nature · doi:10.1038/nature08550 · Cited by 250 · see citing works
Break-Induced Replication: The Where, The Why, and The How
Kramara, J., Osia, B., & Malkova, A. (2018) · Trends in Genetics · doi:10.1016/j.tig.2018.04.002 · Cited by 234 · see citing works
Kreuzer, K. N. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012674 · Cited by 228 · see citing works
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
Hess, G. T., Tycko, J., Yao, D., & Bassik, M. C. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.09.029 · Cited by 234 · see citing works
In vivo base editing of post-mitotic sensory cells
Yeh, W.-H., Chiang, H., Rees, H. A., Edge, A. S. B., & Liu, D. R. (2018) · Nature Communications · doi:10.1038/s41467-018-04580-3 · Cited by 225 · see citing works
CRISPR base editors: genome editing without double-stranded breaks
Eid, A., Alshareef, S. A., & Mahfouz, M. M. (2018) · Biochemical Journal · doi:10.1042/bcj20170793 · Cited by 229 · see citing works
Ciccia, A., Bredemeyer, A. L., Sowa, M. E., Terret, M., Jallepalli, P. V., Harper, J. W., & Elledge, S. J. (2009) · Genes & Development · doi:10.1101/gad.1832309 · Cited by 217 · see citing works
Replication fork reversal and the maintenance of genome stability
Atkinson, J., & McGlynn, P. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp244 · Cited by 221 · see citing works
Chromosome Replication and Segregation in Bacteria
Reyes‐Lamothe, R., Nicolas, É., & Sherratt, D. J. (2012) · Annual Review of Genetics · doi:10.1146/annurev-genet-110711-155421 · Cited by 207 · see citing works
Regulation of long non-coding RNAs and genome dynamics by the RNA surveillance machinery
Nair, L., Chung, H., & Basu, U. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0209-0 · Cited by 203 · see citing works
The replisome uses mRNA as a primer after colliding with RNA polymerase
Pomerantz, R. T., & O’Donnell, M. E. (2008) · Nature · doi:10.1038/nature07527 · Cited by 190 · see citing works
Mechanism and regulation of incisions during DNA interstrand cross-link repair
Zhang, J., & Walter, J. C. (2014) · DNA repair · doi:10.1016/j.dnarep.2014.03.018 · Cited by 187 · see citing works
Co-directional replication–transcription conflicts lead to replication restart
Merrikh, H., Machón, C., Grainger, W. H., Grossman, A. D., & Soultanas, P. (2011) · Nature · doi:10.1038/nature09758 · Cited by 187 · see citing works
RecQ helicases: guardian angels of the DNA replication fork
Bachrati, C. Z., & Hickson, I. D. (2008) · Chromosoma · doi:10.1007/s00412-007-0142-4 · Cited by 180 · see citing works
RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA
Lazzaro, F., Novarina, D., Amara, F., Watt, D. L., Stone, J. E., Costanzo, V., Burgers, P., Kunkel, T. A., Plevani, P., & Muzi-Falconi, M. (2012) · Molecular Cell · doi:10.1016/j.molcel.2011.12.019 · Cited by 177 · see citing works
Precision genome editing using cytosine and adenine base editors in mammalian cells
Huang, T. P., Newby, G. A., & Liu, D. R. (2021) · Nature Protocols · doi:10.1038/s41596-020-00450-9 · Cited by 175 · see citing works
Rep Provides a Second Motor at the Replisome to Promote Duplication of Protein-Bound DNA
Guy, C. P., Atkinson, J., Gupta, M. K., Mahdi, A. A., Gwynn, E. J., Rudolph, C. J., Moon, P. B., van Knippenberg, I. C., Cadman, C. J., Dillingham, M. S., et al. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.11.009 · Cited by 163 · see citing works
Interaction of the Human DNA Glycosylase NEIL1 with Proliferating Cell Nuclear Antigen
Hong, D., Theriot, C. A., Das, A., Hegde, M. L., Matsumoto, Y., Boldogh, I. R., Hazra, T. K., Bhakat, K. K., & MITRA, S. P. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m709186200 · Cited by 147 · see citing works
Costes, A., Lecointe, F., McGovern, S., Quevillon‐Chéruel, S., & Polard, P. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001238 · Cited by 138 · see citing works
Regulation of DNA strand exchange in homologous recombination
Holthausen, J. T., Wyman, C., & Kanaar, R. (2010) · DNA repair · doi:10.1016/j.dnarep.2010.09.014 · Cited by 136 · see citing works
A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V
Patel, M., Jiang, Q., Woodgate, R., Cox, M. M., & Goodman, M. F. (2010) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2010.480968 · Cited by 135 · see citing works
Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion
Leman, A. R., Noguchi, C., Lee, C. Y., & Noguchi, E. (2010) · Journal of Cell Science · doi:10.1242/jcs.057984 · Cited by 130 · see citing works
Directed Evolution of Ionizing Radiation Resistance in Escherichia coli
Harris, D. R., Pollock, S. V., Wood, E. A., Goiffon, R., Klingele, A. J., Cabot, E. L., Schackwitz, W., Martin, J., Eggington, J. M., Durfee, T. J., et al. (2009) · Journal of Bacteriology · doi:10.1128/jb.00502-09 · Cited by 132 · see citing works
The Escherichia coli Replisome Is Inherently DNA Damage Tolerant
Yeeles, J. T. P., & Marians, K. J. (2011) · Science · doi:10.1126/science.1209111 · Cited by 134 · see citing works
Self-citationDNA breaks and chromosomal aberrations arise when replication meets base excision repair
Ensminger, M., Iloff, L., Ebel, C., Nikolova, T., Kaina, B., & Löbrich, M. (2014) · The Journal of Cell Biology · doi:10.1083/jcb.201312078 · Cited by 138 · see citing works
Fumasoni, M., Zwicky, K., Vanoli, F., Lopes, M., & Branzei, D. (2015) · Molecular Cell · doi:10.1016/j.molcel.2014.12.038 · Cited by 138 · see citing works
Break induced replication in eukaryotes: mechanisms, functions, and consequences
Sakofsky, C. J., & Malkova, A. (2017) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2017.1314444 · Cited by 128 · see citing works
Leela, J. K., Syeda, A. H., Anupama, K., & Gowrishankar, J. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1213123110 · Cited by 123 · see citing works
Anticipating chromosomal replication fork arrest: SSB targets repair DNA helicases to active forks
Lecointe, F., Sérèna, C., Velten, M., Costes, A., McGovern, S., Meile, J., Errington, J., Ehrlich, S. D., Noirot, P. H., & Polard, P. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601848 · Cited by 119 · see citing works
Highly organized DnaA– oriC complexes recruit the single-stranded DNA for replication initiation
Ozaki, S., & Katayama, T. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr832 · Cited by 118 · see citing works
Frequent exchange of the DNA polymerase during bacterial chromosome replication
Beattie, T. R., Kapadia, N., Nicolas, É., Uphoff, S., Wollman, A. J. M., Leake, M. C., & Reyes‐Lamothe, R. (2017) · eLife · doi:10.7554/elife.21763 · Cited by 118 · see citing works
Musich, P. R., & Zou, Y. (2009) · Aging · doi:10.18632/aging.100012 · Cited by 117 · see citing works
Liu, Y., Wang, Y., Rusinol, A. E., Sinensky, M. S., Liu, J., Shell, S. M., & Zou, Y. (2008) · The FASEB Journal · doi:10.1096/fj.07-8598com · Cited by 115 · see citing works
Lessons from 50 years of SOS DNA-damage-induced mutagenesis
Schlacher, K., & Goodman, M. F. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2198 · Cited by 114 · see citing works
Replication Fork Reversal after Replication–Transcription Collision
de Septenville, A. L., Duigou, S., Boubakri, H., & Michel, B. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002622 · Cited by 113 · see citing works
Discovery of a Novel Function for Human Rad51
Sage, J. M., Gildemeister, O. S., & Knight, K. L. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.099846 · Cited by 112 · see citing works
Structural mechanisms of PriA-mediated DNA replication restart
Bhattacharyya, B., George, N. P., Thurmes, T. M., Zhou, R., Jani, N. M., Wessel, S. R., Sandler, S. J., Ha, T., & Keck, J. L. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1318001111 · Cited by 112 · see citing works
Increasing the efficiency and precision of prime editing with guide RNA pairs
Zhuang, Y., Liu, J., Wu, H., Zhu, Q., Yan, Y., Meng, H., Chen, P. R., & Yi, C. (2021) · Nature Chemical Biology · doi:10.1038/s41589-021-00889-1 · Cited by 112 · see citing works
Hegde, M. L., Theriot, C. A., Das, A., Hegde, P. M., Guo, Z., Gary, R. K., Hazra, T. K., Shen, B., & MITRA, S. P. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m802712200 · Cited by 107 · see citing works
Continued primer synthesis at stalled replication forks contributes to checkpoint activation
Van, C., Yan, S., Michael, W. M., Waga, S., & Cimprich, K. A. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.200909105 · Cited by 100 · see citing works
Richard, D. J., Bolderson, E., & Khanna, K. K. (2009) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230902849180 · Cited by 106 · see citing works
The replication fork trap and termination of chromosome replication
Duggin, I. G., Wake, R. G., Bell, S. D., & Hill, T. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06500.x · Cited by 105 · see citing works
Minding the gap: The underground functions of BRCA1 and BRCA2 at stalled replication forks
Nagaraju, G., & Scully, R. (2007) · DNA repair · doi:10.1016/j.dnarep.2007.02.020 · Cited by 103 · see citing works
The unnamed complex: what do we know about Smc5-Smc6?
Piccoli, G. D., Torres‐Rosell, J., & Aragón, L. (2009) · Chromosome Research · doi:10.1007/s10577-008-9016-8 · Cited by 101 · see citing works
The role of RPA2 phosphorylation in homologous recombination in response to replication arrest
Shi, W., Feng, Z., Zhang, J., González-Suárez, I., Vanderwaal, R. P., Wu, X., Powell, S. N., Roti, J. L. R., Gonzalo, S., & Zhang, J. (2010) · Carcinogenesis · doi:10.1093/carcin/bgq035 · Cited by 95 · see citing works
Structure of the DNA Repair Helicase Hel308 Reveals DNA Binding and Autoinhibitory Domains
Richards, J. D., Johnson, K. A., Liu, H., McRobbie, A.-M., McMahon, S. A., Oke, M., Carter, L. G., Naismith, J. H., & White, M. F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m707548200 · Cited by 98 · see citing works
The DNA damage response acts as a safeguard against harmful DNA–RNA hybrids of different origins
Barroso, S. I., Herrera‐Moyano, E., Muñoz, S., García-Rubio, M. L., Gómez‐González, B., & Aguilera, A. (2019) · EMBO Reports · doi:10.15252/embr.201847250 · Cited by 97 · see citing works
Gabbai, C. B., & Marians, K. J. (2010) · DNA repair · doi:10.1016/j.dnarep.2009.12.009 · Cited by 97 · see citing works
Self-citationAAA+ ATPases in the Initiation of DNA Replication
Duderstadt, K. E., & Berger, J. M. (2008) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230802058296 · Cited by 96 · see citing works
Replisome mechanics: insights into a twin DNA polymerase machine
Pomerantz, R. T., & O’Donnell, M. E. (2007) · Trends in Microbiology · doi:10.1016/j.tim.2007.02.007 · Cited by 92 · see citing works
FANCM regulates DNA chain elongation and is stabilized by S‐phase checkpoint signalling
Luke-Glaser, S., Luke, B., Grossi, S., & Constantinou, A. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.371 · Cited by 91 · see citing works
The conflict between DNA replication and transcription
McGlynn, P., Savery, N. J., & Dillingham, M. S. (2012) · Molecular Microbiology · doi:10.1111/j.1365-2958.2012.08102.x · Cited by 92 · see citing works
Recovery of Arrested Replication Forks by Homologous Recombination Is Error-Prone
Iraqui, I., Chekkal, Y., Jmari, N., Pietrobon, V., Fréon, K., Costes, A., & Lambert, S. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002976 · Cited by 89 · see citing works
Repair of DNA Breaks by Break-Induced Replication
Kockler, Z. W., Osia, B., Lee, R. H. C., Musmaker, K., & Malkova, A. (2021) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-081420-095551 · Cited by 86 · see citing works
Yeeles, J. T. P., & Dillingham, M. S. (2010) · DNA repair · doi:10.1016/j.dnarep.2009.12.016 · Cited by 90 · see citing works
Chastain, M., Zhou, Q., Shiva, O., Fadri-Moskwik, M., Whitmore, L. S., Jia, P., Dai, X., Huang, C.-H., Ye, P., & Chai, W.-H. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.06.077 · Cited by 79 · see citing works
Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiaePreprint
Szyjka, S. J., Aparicio, J. G., Viggiani, C. J., Knott, S., Xu, W., Tavaré, S., & Aparicio, O. M. (2008) · Genes & Development · doi:10.1101/gad.1660408 · Cited by 89 · see citing works
The S-Phase Checkpoint Is Required To Respond to R-Loops Accumulated in THO Mutants
Gómez‐González, B., Felipe‐Abrio, I., & Aguilera, A. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.00402-09 · Cited by 87 · see citing works
Xer Site Specific Recombination: Double and Single Recombinase Systems
Martinez, F. A. C., Benmohamed, A., & Szatmari, G. B. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00453 · Cited by 87 · see citing works
What happens when replication and transcription complexes collide?
Pomerantz, R. T., & O’Donnell, M. E. (2010) · Cell Cycle · doi:10.4161/cc.9.13.12122 · Cited by 86 · see citing works
A Hand-Off Mechanism for Primosome Assembly in Replication Restart
Lopper, M. E., Boonsombat, R., Sandler, S. J., & Keck, J. L. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.05.012 · Cited by 86 · see citing works
Is RecG a general guardian of the bacterial genome?
Rudolph, C. J., Upton, A. L., Briggs, G. S., & Lloyd, R. G. (2010) · DNA repair · doi:10.1016/j.dnarep.2009.12.014 · Cited by 83 · see citing works
Drosophila timeless2 Is Required for Chromosome Stability and Circadian Photoreception
Benna, C., Bonaccorsi, S., Wülbeck, C., Helfrich‐Förster, C., Gatti, M., Kyriacou, C. P., Costa, R., & Sandrelli, F. (2010) · Current Biology · doi:10.1016/j.cub.2009.12.048 · Cited by 82 · see citing works
Bailis, J. M., Luche, D. D., Hunter, T. R., & Forsburg, S. L. (2008) · Molecular and Cellular Biology · doi:10.1128/mcb.01717-07 · Cited by 79 · see citing works
Dynamics of Leading-Strand Lesion Skipping by the Replisome
Yeeles, J. T. P., & Marians, K. J. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.10.020 · Cited by 80 · see citing works
Self-citationThe E. coli DNA Replication Fork
Lewis, J. S., Jergic, S., & Dixon, N. E. (2016) · The Enzymes · doi:10.1016/bs.enz.2016.04.001 · Cited by 80 · see citing works
RAD6-RAD18-RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light
Hishida, T., Kubota, Y., Carr, A. M., & Iwasaki, H. (2009) · Nature · doi:10.1038/nature07580 · Cited by 77 · see citing works
Wu, Y., Lee, S., Williamson, E. A., Reinert, B. L., Cho, J. H., Xia, F., Jaiswal, A. S., Srinivasan, G., Patel, B., Brantley, A., et al. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005675 · Cited by 77 · see citing works
Bhattacharjee, S., & Nandi, S. (2017) · IUBMB Life · doi:10.1002/iub.1696 · Cited by 75 · see citing works
Timing and spacing of ubiquitin‐dependent DNA damage bypass
Ulrich, H. D. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.05.028 · Cited by 73 · see citing works
BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids
Chandramouly, G., Kwok, A., Huang, B., Willis, N. A., Xie, A., & Scully, R. (2013) · Nature Communications · doi:10.1038/ncomms3404 · Cited by 74 · see citing works
Telomere ResQue and preservation—Roles for the Werner syndrome protein and other RecQ helicases
Opresko, P. L. (2007) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2007.10.007 · Cited by 72 · see citing works
Homologous Recombination as a Replication Fork Escort: Fork-Protection and Recovery
Costes, A., & Lambert, S. (2012) · Biomolecules · doi:10.3390/biom3010039 · Cited by 71 · see citing works
Coordinating DNA polymerase traffic during high and low fidelity synthesis
Sutton, M. D. (2009) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2009.06.010 · Cited by 72 · see citing works
Protein–DNA complexes are the primary sources of replication fork pausing in Escherichia coli
Gupta, M. K., Guy, C. P., Yeeles, J. T. P., Atkinson, J., Bell, H., Lloyd, R., Marians, K., & McGlynn, P. (2013) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.1303890110 · Cited by 80 · see citing works
Self-citationKozlov, A. G., Jezewska, M. J., Bujalowski, W., & Lohman, T. M. (2010) · Biochemistry · doi:10.1021/bi100069s · Cited by 69 · see citing works
Homologous Recombination—Enzymes and Pathways
Michel, B., & Leach, D. R. F. (2012) · EcoSal Plus · doi:10.1128/ecosalplus.7.2.7 · Cited by 65 · see citing works
Recombination and ReplicationPreprint
Syeda, A. H., Hawkins, M., & McGlynn, P. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a016550 · Cited by 62 · see citing works
Wen, Q., Scorah, J., Phear, G. A., Rodgers, G. R., Rodgers, S., & Meuth, M. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-09-0975 · Cited by 61 · see citing works
Deciphering the Code of the Cancer Genome: Mechanisms of Chromosome Rearrangement
Willis, N. A., Rass, E., & Scully, R. (2015) · Trends in cancer · doi:10.1016/j.trecan.2015.10.007 · Cited by 62 · see citing works
Role of the BLM helicase in replication fork management
Wu, L. P. (2007) · DNA repair · doi:10.1016/j.dnarep.2007.02.007 · Cited by 61 · see citing works
25 years on and no end in sight: a perspective on the role of RecG protein
Lloyd, R. G., & Rudolph, C. J. (2016) · Current Genetics · doi:10.1007/s00294-016-0589-z · Cited by 58 · see citing works
Rass, U. (2013) · Chromosoma · doi:10.1007/s00412-013-0431-z · Cited by 59 · see citing works
Molecular Anatomy of the Recombination Mediator Function of Saccharomyces cerevisiae Rad52
Seong, C., Sehorn, M. G., Plate, I., Shi, I. Y., Song, B., Chi, P., Mortensen, U. H., Sung, P., & Krejčí, L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m800763200 · Cited by 59 · see citing works
DNA interstrand crosslink repair in mammalian cells
McCabe, K. M., Olson, S. B., & Moses, R. E. (2009) · Journal of Cellular Physiology · doi:10.1002/jcp.21811 · Cited by 59 · see citing works
Differentiation of the DnaA-oriC Subcomplex for DNA Unwinding in a Replication Initiation Complex
Ozaki, S., Noguchi, Y., Hayashi, Y., Miyazaki, E., & Katayama, T. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.372052 · Cited by 58 · see citing works
- Authors
- Heller, R. C., & Marians, K. J.
- Affiliations
- Memorial Sloan Kettering Cancer Center (US)
- Corresponding author
- Marians, Kenneth J.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2006-11-08
- Volume
- 7
- Issue
- 12
- Pages
- 932-943
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W2083344047
- Cited by
- 268
- References
- 101
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 4 · 2022: 6 · 2021: 12 · 2020: 9 · 2019: 6 · 2018: 11 · 2017: 16 · 2016: 11 · 2015: 11 · 2014: 13 · 2013: 21 · 2012: 22
- FWCI
- 2.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Molecular Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of General Medical Sciences (R37GM034557)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Keywords
- replisome assembly, replication fork stalling, replication fork restart, replication fork collapse, genomic instability, DNA damage, recombination, replication restart
- MeSH terms
- Animals, DNA Repair, DNA Replication, DNA Helicases, DNA-Binding Proteins, Eukaryotic Cells, Humans, Prokaryotic Cells, Recombination, Genetic, Replicon
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review