Most cited biochemistry, genetics and molecular biology papers
- Verified
The Functional Block of TNF but Not of IL-6 Prevents Bone Loss in Ovariectomized Mice
Kimble, R. B., Bain, S., & Pacifici, R. (1997) · Journal of Bone and Mineral Research
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 241
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Biosynthesis of human colonic mucin: Muc2 is the prominent secretory mucin
Tytgat, K. M. A. J., Büller, H. A., Opdam, F. J. M., Kim, Y. S., Einerhand, A. W. C., & Dekker, J. (1994) · Gastroenterology
Glycosylation and Glycoproteins ResearchProteoglycans and glycosaminoglycans research
Cited by 241
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Primary cilia of human endothelial cells disassemble under laminar shear stress
Iomini, C., Tejada, K., Mo, W., Vaananen, H., & Piperno, G. (2004) · The Journal of Cell Biology
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 241
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Physiological role of AMP-activated protein kinase (AMPK): insights from knockout mouse models
Viollet, B., Andreelli, F., Jørgensen, S. B., Perrin, C., Flamez, D., Mu, J., Wojtaszewski, J. F. P., Schuit, F. C., Birnbaum, M., Richter, E., et al. (2003) · Biochemical Society Transactions
Metabolism, Diabetes, and CancerPancreatic function and diabetes
Cited by 241
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Single-cell transcriptomic analyses of the developing meninges reveal meningeal fibroblast diversity and function.
DeSisto, J., O’Rourke, R., Jones, H. E., Pawlikowski, B., Malek, A. D., Bonney, S., Guimiot, F., Jones, K. L., & Siegenthaler, J. A. (2020) · Developmental Cell
Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms
Cited by 241
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PPAR-α–Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance
Guerre-Millo, M., Rouault, C., Poulain, P., André, J., Poitout, V., Peters, J. M., Gonzalez, F. J., Fruchart, J.-C., Reach, G., & Staels, B. (2001) · Diabetes
Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases
Cited by 241
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A third component causing random variability beside environment and genotype. A reason for the limited success of a 30 year long effort to standardize laboratory animals?
Gärtner, K. (1990) · Laboratory Animals
Genetic and phenotypic traits in livestockAnimal Behavior and Reproduction
Cited by 241
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Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA Population
Simhadri, V. L., McGill, J., McMahon, S., Wang, J., Jiang, H., & Sauna, Z. E. (2018) · Molecular Therapy - Methods & Clinical Development
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 241
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The α2–5′AMP-Activated Protein Kinase Is a Site 2 Glycogen Synthase Kinase in Skeletal Muscle and Is Responsive to Glucose Loading
Jørgensen, S. B., Nielsen, J. N., Birk, J. B., Olsen, G. S., Viollet, B., Andreelli, F., Schjerling, P., Vaulont, S., Hardie, D. G., Hansen, B. F., et al. (2004) · Diabetes
Metabolism, Diabetes, and CancerGlycogen Storage Diseases and Myoclonus
Cited by 241
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Hyperinsulinaemia in cancer
Gallagher, E. J., & LeRoith, D. (2020) · Nature Reviews Cancer
Metabolism, Diabetes, and CancerCancer, Lipids, and Metabolism
Cited by 241
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Plasma extracellular vesicle long RNA profiling identifies a diagnostic signature for the detection of pancreatic ductal adenocarcinoma
Yu, S., Li, Y., Liao, Z., Wang, Z., Wang, Z., Li, Y., Qian, L., Zhao, J., Zong, H., Kang, B., et al. (2020) · Gut
Extracellular vesicles in diseasePancreatic and Hepatic Oncology Research
Cited by 241
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Global Genetic Networks and the Genotype-to-Phenotype Relationship
Costanzo, M., Kuzmin, E., van Leeuwen, J., Mair, B., Moffat, J., Boone, C., & Andrews, B. (2019) · Cell
Bioinformatics and Genomic NetworksGene Regulatory Network Analysis
Cited by 241
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Catalases of Aspergillus fumigatus
Paris, S., Wysong, D., Debeaupuis, J.-P., Shibuya, K., Philippe, B., Diamond, R. D., & Latgé, J.-P. (2003) · Infection and Immunity
Fungal and yeast genetics researchAntifungal resistance and susceptibility
Cited by 241
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Mechanisms involved in the regulation of histone lysine demethylases
Lan, F., Nottke, A. C., & Shi, Y. (2008) · Current Opinion in Cell Biology
Epigenetics and DNA MethylationCancer-related gene regulation
Cited by 241
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A review of microsatellite markers and their applications in rice breeding programs to improve blast disease resistance
Miah, G., Rafii, M., Ismail, M., Puteh, A., Rahim, H., Islam, K., & Latif, M. (2013) · International Journal of Molecular Sciences
Genetic Mapping and Diversity in Plants and AnimalsPlant Disease Resistance and Genetics
Cited by 241
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Loss of linker histone H1 in cellular senescence
Funayama, R., Saito, M., Tanobe, H., & Ishikawa, F. (2006) · The Journal of Cell Biology
Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics
Cited by 241
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The ATP‐sensitivity of K+ channels in rat pancreatic B‐cells is modulated by ADP
Kakei, M., Kelly, R. P., Ashcroft, S. J. H., & Ashcroft, F. M. (1986) · FEBS Letters
Ion channel regulation and functionPancreatic function and diabetes
Cited by 241
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DNA Is Packaged within Membrane-Derived Vesicles of Gram-Negative but Not Gram-Positive Bacteria
Dorward, D. W., & Garon, C. F. (1990) · Applied and Environmental Microbiology
Bacterial Genetics and BiotechnologyBacterial Infections and Vaccines
Cited by 241
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Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9
Chen, Y., Zheng, Y., Kang, Y., Yang, W., Niu, Y., Guo, X., Tu, Z., Si, C., Wang, H., Xing, R., et al. (2015) · Human Molecular Genetics
CRISPR and Genetic EngineeringMuscle Physiology and Disorders
Cited by 241
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Lagging-strand replication shapes the mutational landscape of the genome
Reijns, M. A. M., Kemp, H., Ding, J., Marion de Procé, S., Jackson, A. P., & Taylor, M. S. (2015) · Nature
DNA Repair MechanismsEvolution and Genetic Dynamics
Cited by 241
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Protein interaction networks revealed by proteome coevolution
Cong, Q., Anishchenko, I., Ovchinnikov, S., & Baker, D. (2019) · Science
Bioinformatics and Genomic NetworksProtein Structure and Dynamics
Cited by 241
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Curated variation benchmarks for challenging medically relevant autosomal genes
Wagner, J., Olson, N. D., Harris, L., McDaniel, J., Cheng, H., Fungtammasan, A., Hwang, Y.-C., Gupta, R., Wenger, A. M., Rowell, W. J., et al. (2022) · Nature Biotechnology
Genomics and Phylogenetic StudiesGenomics and Rare Diseases
Cited by 241
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Modeling fragile X syndrome in the Fmr1 knockout mouse
Kazdoba, T. M., Leach, P. T., Silverman, J. L., & Crawley, J. N. (2014) · Intractable & Rare Diseases Research
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 241
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Techniques and probes for the study of Xenopus tropicalis development
Khokha, M. K., Chung, C., Bustamante, E. L., Gaw, L. W. K., Trott, K. A., Yeh, J., Lim, N., Lin, J. C. Y., Taverner, N., Amaya, E., et al. (2002) · Developmental Dynamics
Developmental Biology and Gene RegulationZebrafish Biomedical Research Applications
Cited by 241
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