Most cited biochemistry, genetics and molecular biology papers
- Verified
Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey
Vandenberghe, L. H., Bell, P., Maguire, A. M., Cearley, C. N., Xiao, R., Calcedo, R., Wang, L., Castle, M. J., Maguire, A. C., Grant, R., et al. (2011) · Science Translational Medicine
Virus-based gene therapy researchRetinal Development and Disorders
Cited by 242
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Characterization of the spectrum of insecticidal activity of a double-stranded RNA with targeted activity against western corn rootworm (Diabrotica virgifera virgifera LeConte)
Bachman, P. M., Bolognesi, R., Moar, W. J., Mueller, G. M., Paradise, M. S., Ramaseshadri, P., Tan, J., Uffman, J. P., Warren, J., Wiggins, B. E., et al. (2013) · Transgenic Research
Insect Resistance and GeneticsInsect Pest Control Strategies
Cited by 242
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Transcription‐coupled repair removes both cyclobutane pyrimidine dimers and 6‐4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts.
van Hoffen, A., Venema, J., Meschini, R., van Zeeland, A. A., & Mullenders, L. H. (1995) · The EMBO Journal
DNA Repair MechanismsNuclear Structure and Function
Cited by 242
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Cellular siRNA delivery using cell-penetrating peptides modified for endosomal escape
Endoh, T., & Ohtsuki, T. (2009) · Advanced Drug Delivery Reviews
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 242
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Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.
Brass, A. L., Kehrli, E., Eisenbeis, C. F., Storb, U., & Singh, H. (1996) · Genes & Development
Genomics and Chromatin Dynamicsinterferon and immune responses
Cited by 242
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Reactive Oxygen Species as Mediators of Cellular Senescence
Colavitti, R., & Finkel, T. (2005) · IUBMB Life
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 242
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Plasma Trimethylamine N -Oxide, a Gut Microbe–Generated Phosphatidylcholine Metabolite, Is Associated With Atherosclerotic Burden
Senthong, V., Li, X. S., Hudec, T., Coughlin, J., Wu, Y., Levison, B., Wang, Z., Hazen, S. L., & Tang, W. H. W. (2016) · Journal of the American College of Cardiology
Gut microbiota and healthAtherosclerosis and Cardiovascular Diseases
Cited by 242
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Modulation of Hippocampus-Dependent Learning and Synaptic Plasticity by Nicotine
Kenney, J. W., & Gould, T. J. (2008) · Molecular Neurobiology
Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research
Cited by 242
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The Causes and Consequences of Genetic Interactions (Epistasis)
Domingo, J., Baeza-Centurion, P., & Lehner, B. (2019) · Annual Review of Genomics and Human Genetics
Evolution and Genetic DynamicsRNA and protein synthesis mechanisms
Cited by 242
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Sherlock: Detecting Gene-Disease Associations by Matching Patterns of Expression QTL and GWAS
He, X., Fuller, C. K., Song, Y., Meng, Q., Zhang, B., Yang, X., & Li, H. (2013) · The American Journal of Human Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 241
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RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media
Conrad, T. M., Frazier, M., Joyce, A. R., Cho, B.-K., Knight, E. M., Lewis, N. E., Landick, R., & Palsson, B. Ø. (2010) · Proceedings of the National Academy of Sciences
Bacterial Genetics and BiotechnologyEvolution and Genetic Dynamics
Cited by 241
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Peroxisomal and Mitochondrial Fatty Acid β-Oxidation in Mice Nullizygous for Both Peroxisome Proliferator-activated Receptor α and Peroxisomal Fatty Acyl-CoA Oxidase
Hashimoto, T., Fujita, T., Usuda, N., Cook, W., Qi, C., Peters, J. M., Gonzalez, F. J., Yeldandi, A. V., Rao, M. S., & Reddy, J. K. (1999) · Journal of Biological Chemistry
Peroxisome Proliferator-Activated ReceptorsMetabolism and Genetic Disorders
Cited by 241
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KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
Schumann, G., Liu, C., O’Reilly, P., Gao, H., Song, P., Xu, B., Ruggeri, B., Amin, N., Jia, T., Preis, S., et al. (2016) · Proceedings of the National Academy of Sciences
Fibroblast Growth Factor ResearchNeurotransmitter Receptor Influence on Behavior
Cited by 241
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Non-alcoholic fatty liver and the gut microbiota
Bashiardes, S., Shapiro, H., Rozin, S., Shibolet, O., & Elinav, E. (2016) · Molecular Metabolism
Gut microbiota and healthLiver Disease Diagnosis and Treatment
Cited by 241
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Emerging Role of cAMP/AMPK Signaling
Aslam, M., & Ladilov, Y. (2022) · Cells
Metabolism, Diabetes, and CancerPhosphodiesterase function and regulation
Cited by 241
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Hairpin RNA: a secondary structure of primary importance
Svoboda, P., & Cara, A. D. (2006) · Cellular and Molecular Life Sciences
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 241
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Understanding metric-related pitfalls in image analysis validation
Reinke, A., Tizabi, M. D., Baumgartner, M., Eisenmann, M., Heckmann-Nötzel, D., Kavur, A. E., Rädsch, T., Sudre, C. H., Acion, L., Antonelli, M., et al. (2024) · Nature Methods
Cell Image Analysis TechniquesMedical Image Segmentation Techniques
Cited by 241
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Characterization of individual tryptophan side chains in proteins using Raman spectroscopy and hydrogen-deuterium exchange kinetics
Miura, T., Takeuchi, H., & Harada, I. (1988) · Biochemistry
Spectroscopy Techniques in Biomedical and Chemical ResearchProtein Structure and Dynamics
Cited by 241
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Bile acid modifications at the microbe-host interface: potential for nutraceutical and pharmaceutical interventions in host health
Joyce, S. A., & Gahan, C. G. M. (2016) · Annual Review of Food Science and Technology
Gut microbiota and healthDrug Transport and Resistance Mechanisms
Cited by 241
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Immune responses to AAV in a phase I study for Canavan disease
McPhee, S. W. J., Janson, C. G., Li, C., Samulski, R. J., Camp, A. S., Francis, J., Shera, D., Lioutermann, L., Feely, M., Freese, A., et al. (2006) · The Journal of Gene Medicine
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 241
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Role of PSIP1/LEDGF/p75 in Lentiviral Infectivity and Integration Targeting
Marshall, H. M., Ronen, K., Berry, C., Llano, M., Sutherland, H., Saenz, D., Bickmore, W., Poeschla, E., & Bushman, F. D. (2007) · PLoS ONE
Virus-based gene therapy researchHIV Research and Treatment
Cited by 241
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Smith–Magenis syndrome
Elsea, S. H., & Girirajan, S. (2008) · European Journal of Human Genetics
Genomic variations and chromosomal abnormalitiesGenetics and Neurodevelopmental Disorders
Cited by 241
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Arbutin as a Skin Depigmenting Agent with Antimelanogenic and Antioxidant Properties
Boo, Y. C. (2021) · Antioxidants
melanin and skin pigmentationDermatologic Treatments and Research
Cited by 241
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Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators
Song, G., Yang, D., Wang, Y., de Graaf, C., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., et al. (2017) · Nature
Receptor Mechanisms and SignalingDiabetes Treatment and Management
Cited by 241
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