The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Association Between Blood Pressure Level and the Risk of Myocardial Infarction, Stroke, and Total Mortality: The Cardiovascular Health Study
Abstract
BACKGROUND: Recent reports have drawn attention to the importance of pulse pressure as a predictor of cardiovascular events. Pulse pressure is used neither by clinicians nor by guidelines to define treatable levels of blood pressure. METHODS: In the Cardiovascular Health Study, 5888 adults 65 years and older were recruited from 4 US centers. At baseline in 1989-1990, participants underwent an extensive examination, and all subsequent cardiovascular events were ascertained and classified. RESULTS: At baseline, 1961 men and 2941 women were at risk for an incident myocardial infarction or stroke. During follow-up that averaged 6.7 years, 572 subjects had a coronary event, 385 had a stroke, and 896 died. After adjustment for potential confounders, systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse pressure were directly associated with the risk of incident myocardial infarction and stroke. Only SBP was associated with total mortality. Importantly, SBP was a better predictor of cardiovascular events than DBP or pulse pressure. In the adjusted model for myocardial infarction, a 1-SD change in SBP, DBP, and pulse pressure was associated with hazard ratios (95% confidence intervals) of 1.24 (1.15-1.35), 1.13 (1.04-1.22), and 1.21 (1.12-1.31), respectively; and adding pulse pressure or DBP to the model did not improve the fit. For stroke, the hazard ratios (95% confidence intervals) were 1.34 (1.21-1.47) with SBP, 1.29 (1.17-1.42) with DBP, and 1.21 (1.10-1.34) with pulse pressure. The association between blood pressure level and cardiovascular disease risk was generally linear; specifically, there was no evidence of a J-shaped relationship. In those with treated hypertension, the hazard ratios for the association of SBP with the risks for myocardial infarction and stroke were less pronounced than in those without treated hypertension. CONCLUSION: In this population-based study of older adults, although all measures of blood pressure were strongly and directly related to the risk of coronary and cerebrovascular events, SBP was the best single predictor of cardiovascular events.
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Cites
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Self-citationMACMAHON, S. (1990) · The Lancet · doi:10.1016/0140-6736(90)90878-9 · Cited by 4,253 · cited 1×
“”(1) This judgment reflects findings from numerous studies, including the Framingham Heart Study,(2,3) the screenees from the Multiple Risk Factor Intervention Trial,(1,4) and a major metaanalysis.(5) Although the relationship may be stronger for systolic blood pressure (SBP) than for diastolic blood pressure (DBP),(3…”
BackgroundThe Cardiovascular Health Study: design and rationale.
Fried, L. P., Borhani, N. O., Enright, P., Furberg, C. D., Gardin, J. M., Kronmal, R. A., Kuller, L. H., Manolio, T. A., Mittelmark, M. B., Newman, A., et al. (1991) · Annals of Epidemiology · doi:10.1016/1047-2797(91)90005-w · Cited by 3,652
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Midlife Hypertension and Alzheimer’s Disease: A Systematic Review and Meta-Analysis
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Liu, K., Colangelo, L. A., Daviglus, M. L., Goff, D. C., Pletcher, M., Schreiner, P. J., Sibley, C. T., Burke, G. L., Post, W. S., Michos, E. D., et al. (2015) · Journal of the American Heart Association · doi:10.1161/jaha.115.002275 · Cited by 128
Bakris, G. L., Weir, M. R., & on behalf of the Study of Hypertension and the Efficacy of Lotrel in Diabetes (SHIELD) Investigators (2003) · The Journal of Clinical Hypertension · doi:10.1111/j.1524-6175.2002.2041.x · Cited by 94
A high fat meal increases cardiovascular reactivity to psychological stress in healthy young adults
Jakulj, F., Zernicke, K., Bacon, S. L., van Wielingen, L. E., Key, B. L., West, S. G., & Campbell, T. S. (2007) · The Journal of Nutrition · doi:10.1093/jn/137.4.935 · Cited by 91
Bloomer, L. D. S., Nelson, C. P., Eales, J., Denniff, M., Christofidou, P., Debiec, R., Moore, J., Consortium, C., Zukowska-Szczechowska, E., Goodall, A. H., et al. (2013) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.113.301608 · Cited by 75
Nikolic, S. B., Sharman, J. E., Adams, M. J., & Edwards, L. M. (2014) · Journal of Hypertension · doi:10.1097/hjh.0000000000000168 · Cited by 79
Ishikawa, S., Matsumoto, M., Kayaba, K., Gotoh, T., Nago, N., Tsutsumi, A., & Kajii, E. (2009) · Journal of Epidemiology · doi:10.2188/jea.je20080092 · Cited by 23
Allie, E. C., Kane, M. P., Busch, R. S., Bakst, G., & Hamilton, R. A. (2004) · Hospital Pharmacy · doi:10.1177/001857870403900114 · Cited by 3
Metadata
- Authors
- Psaty, B. M., Furberg, C. D., Kuller, L. H., Cushman, M., Savage, P. J., Levine, D., O'Leary, D. H., Bryan, R. N., Anderson, M., & Lumley, T.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2001-05-14
- Volume
- 161
- Issue
- 9
- Pages
- 1183
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2107910831
- Cited by
- 428
- References
- 3
- FWCI
- 17.23
- Type
- journal article
- Language
- en
- Open access
- closed
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