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Cited by 103Vitamin C and Antioxidants ResearchRespiratory viral infections researchExercise and Physiological Responses

Vitamin C prophylaxis in marine recruits

Pitt, Henry A.·1979·JAMA: The Journal of the American Medical Association
DOI 10.1001/jama.1979.03290350028016
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Abstract

A prospective, randomized, double-blind study was carried out to determine whether vitamin C prophylaxis, 2.0 g/day, vs placebo prophylaxis would reduce the incidence or morbidity of the common cold and other respiratory illnesses in 674 marine recruits during an eight-week period. Whole-blood ascorbic acid levels measured six weeks after initiation of the study were significantly higher in the vitamin C group. There was no difference between the two groups in the incidence or duration of colds. The vitamin C group rated their colds as being less severe, but this was not reflected in different symptom complexes or in fewer sick-call visits or training days lost. This study and the literature do not support the prophylactic use of vitamin C to prevent the common cold.

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Crossref · 10.1001/jama.1979.03290350028016

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19 of 19 references verified0 citation errors · 0 not checkable

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  • In Pitt 1979, the standard deviation for duration was not published and was estimated as equal to the mean.

    “SD for duration was not published and it was estimated as SD = mean”

    From Vitamin C for preventing and treating the common cold (2013) · cites this paper as Pitt 1979

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Authors
Pitt, H. A.
Corresponding author
Pitt, Henry A.
ORCID
Pitt, Henry A.
Venue
JAMA: The Journal of the American Medical Association
Publisher
American Medical Association (AMA)
Published
1979-03-02
Volume
241
Issue
9
Pages
908
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
DOI
10.1001/jama.1979.03290350028016
OpenAlex
W2132447415
Cited by
103
References
19
Citations by year
2026: 3 · 2025: 4 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 7 · 2020: 6 · 2018: 1 · 2017: 3 · 2013: 2
FWCI
2.16
Type
journal article
Language
en
Open access
closed
Locations
  • JAMA (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Vitamin C and Antioxidants Research
  • Health Sciences › Medicine › Epidemiology › Respiratory viral infections research
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Keywords
vitamin C, common cold, respiratory diseases, naval recruits
MeSH terms
Ascorbic Acid, Clinical Trials as Topic, Common Cold, Double-Blind Method, Drug Evaluation, Humans, Male, Naval Medicine

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