Cited by 2,835Peripheral Artery Disease ManagementDiabetic Foot Ulcer Assessment and ManagementVascular Procedures and Complications

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Peripheral Arterial Disease Detection, Awareness, and Treatment in Primary Care

Hirsch, Alan T.·2001·JAMA

DOI 10.1001/jama.286.11.1317

Open this paper in CoChat — free account

Abstract

Context Peripheral arterial disease (PAD) is a manifestation of systemic atherosclerosis that is common and is associated with an increased risk of death and ischemic events, yet may be underdiagnosed in primary care practice. Objective To assess the feasibility of detecting PAD in primary care clinics, patient and physician awareness of PAD, and intensity of risk factor treatment and use of antiplatelet therapies in primary care clinics. Design and setting The PAD Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) program, a multicenter, cross-sectional study conducted at 27 sites in 25 cities and 350 primary care practices throughout the United States in June-October 1999. Patients A total of 6979 patients aged 70 years or older or aged 50 through 69 years with history of cigarette smoking or diabetes were evaluated by history and by measurement of the ankle-brachial index (ABI). PAD was considered present if the ABI was 0.90 or less, if it was documented in the medical record, or if there was a history of limb revascularization. Cardiovascular disease (CVD) was defined as a history of atherosclerotic coronary, cerebral, or abdominal aortic aneurysmal disease. Main outcome measures Frequency of detection of PAD; physician and patient awareness of PAD diagnosis; treatment intensity in PAD patients compared with treatment of other forms of CVD and with patients without clinical evidence of atherosclerosis. Results PAD was detected in 1865 patients (29%); 82…

Integrity signals

Registry

Crossref · 10.1001/jama.286.11.1317

Cites

0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Randomized Trial of Estrogen Plus Progestin for Secondary Prevention of Coronary Heart Disease in Postmenopausal Women
Hulley, S. (1998) · JAMA · doi:10.1001/jama.280.7.605 · Cited by 6,216
Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels: Results of AFCAPS/TexCAPS
Downs, J. R., Clearfield, M., Weis, S., Whitney, E., Shapiro, D. R., Beere, P. A., Langendorfer, A., Stein, E. A., Kruyer, W., Gotto, Jr., et al. (1998) · JAMA · doi:10.1001/jama.279.20.1615 · Cited by 5,236

Show all 0 references

Sorted by citations

Items 501–600 of 1,042

Accuracy of ankle–brachial index obtained by automated blood pressure measuring devices in patients with diabetes mellitus
Ena, J., Lozano, T., Verdú, G., Argente, C. R., & González, V. L. (2011) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2011.02.015 · Cited by 13
“[18] Hirsch AT, Criqui MH, Treat-Jacobson D, Regensteiner JG, Creager MA, Olin JW, et al.”
Background
Vascular disease burden and in-hospital outcomes among patients undergoing percutaneous coronary intervention in New York State.
Berger, J., Petersen, J., & Brown, D. L. (2009) · Circulation. Cardiovascular Interventions · doi:10.1161/circinterventions.108.847459.108.847459 · Cited by 17
Imaging coronary and extracoronary atherosclerosis: feasibility and impact of whole-body computed tomography angiography
Napoli, A., Catalano, C., Francone, M., Sciacca, V., Carbone, I., Greco, C., Anzidei, M., Calabrese, F. A., Marincola, B. C., Kirchin, M. A., et al. (2009) · European Radiology · doi:10.1007/s00330-009-1342-5 · Cited by 14
“Additional, larger studies will be required to clarify the value of accurate AVD assessment and primary and secondary AVD prevention in terms of improved patient morbidity and mortality [28, 29].”
Background
Face-to-Face Interaction Compared With Video Watching on Use of Physical Activity in Peripheral Arterial Disease: A Pilot Trial
Collins, T. C., Krueger, P. N., Kroll, T. L., & Sharf, B. F. (2009) · Angiology · doi:10.1177/0003319708318382 · Cited by 17
Medical Management of Peripheral Arterial Disease: A Therapeutic Algorithm
Lumsden, A., & Rice, T. (2006) · Journal of Endovascular Therapy · doi:10.1177/15266028060130s206 · Cited by 17
Cost-effective, risk-free, evidence-based medicine.
Matz, R. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.22.2795-a · Cited by 17
Meeting the challenge of peripheral arterial disease.
Halperin, J., & Fuster, V. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.8.877 · Cited by 17
Costs and medical care consequences associated with the diagnosis of peripheral arterial disease
Migliaccio-Walle, K., Caro, J., Ishak, K., & O'Brien, J. (2012) · PharmacoEconomics (Auckland) · doi:10.2165/00019053-200523070-00007 · Cited by 17
The role of miRNAs in the diagnosis of stable atherosclerosis of different arterial territories: A critical review
Teixeira, A. R., Ferreira, V., Pereira-da-Silva, T., & Ferreira, R. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1040971 · Cited by 16
“Multi-territorial is frequently encountered in clinical practice and is associated with higher morbidity and risk of mortality compared with single-territorial atherosclerosis (16, 90).”
Background
Sex as a Key Determinant of Peripheral Artery Disease: Epidemiology, Differential Outcomes, and Proposed Biological Mechanisms
Morrison, A. M., & Aday, A. W. (2022) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2022.02.021 · Cited by 14
Health Disparities Attributed to Medicare-Medicaid Dual-Eligible Status in Patients with Peripheral Arterial Disease.
Chen, J.-S., Ruiz, K. M. C., Perla, K. M. R., Liu, Y., Nwaiwu, C., & Moreira, C. C. (2021) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2021.11.069 · Cited by 16
Disparities in amputation in patients with peripheral arterial disease
McGinigle, K. L., & Minc, S. D. (2021) · Surgery · doi:10.1016/j.surg.2021.01.025 · Cited by 21
Peripheral arterial disease: Scoping review of patient‐centred outcomes
Bolton, L. L. (2019) · International Wound Journal · doi:10.1111/iwj.13232 · Cited by 20
“Cool, pale, hairless lower leg(s) symptomatic of early PAD are often unnoticed or ignored.(8) Walking pain may increase progressively with exercise, eventually occurring at rest or with brief exercise.”
Background
A Qualitative Study Exploring Patient Concerns and Values in Chronic Limb-Threatening Ischemia.
Aitken, S., Choy, O. S., & Monaro, S. (2019) · Journal of Surgical Research · doi:10.1016/j.jss.2019.05.055 · Cited by 16
Prevalence and Outcomes of Undiagnosed Peripheral Arterial Disease Among High Risk Patients in Australia: An Australian REACH Sub-Study.
Si, S., Golledge, J., Norman, P., Nelson, M., Chew, D., Ademi, Z., Bhatt, D. L., Steg, G., & Reid, C. (2019) · Heart, Lung and Circulation · doi:10.1016/j.hlc.2018.04.292 · Cited by 16
Ankle Brachial Pressure Index: An update for the vascular specialist and general practitioner
Thurston, B., & Dawson, J. (2019) · Vascular · doi:10.1177/1708538119842395 · Cited by 16
Drug-coated balloon in peripheral artery disease.
Shanmugasundaram, M., Murugapandian, S., Truong, H., Lotun, K., & Banerjee, S. (2019) · Cardiovascular Revascularization Medicine · doi:10.1016/j.carrev.2018.04.017 · Cited by 16
Agreement of clinical tests for the diagnosis of peripheral arterial disease.
Azzopardi, Y. M., Gatt, A., Chockalingam, N., & Formosa, C. (2019) · Primary Care Diabetes · doi:10.1016/j.pcd.2018.08.005 · Cited by 16
“Effective long term care of patients with PAD requires an increase in diagnostic efforts within the clinical setting to decrease ischemic complications, systemic cardiovascular risk and improve quality of life [10].”
Background
Myocardial Injury is More Common than Deep Venous Thrombosis after Vascular Surgery and is Associated with a High One Year Mortality Risk.
Górka, J., Polok, K., Fronczek, J., Górka, K., Kózka, M., Iwaszczuk, P., Frolow, M., Devereaux, P., Biccard, B., Musial, J., et al. (2018) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2018.02.005 · Cited by 16
Ankle-Brachial Index Screening and Improving Peripheral Artery Disease Detection and Outcomes
McDermott, M. M., & Criqui, M. H. (2018) · JAMA · doi:10.1001/jama.2018.8953 · Cited by 20
Comparison of EQ-5D and SF-36 in untreated patients with symptoms of intermittent claudication
Vaidya, A., Kleinegris, M., Severens, J. L., Ramaekers, B. L. T., ten Cate‐Hoek, A. J., Cate, H. T., & Joore, M. A. (2018) · Journal of Comparative Effectiveness Research · doi:10.2217/cer-2017-0029 · Cited by 17
PAD in Women: the Ischemic Continuum
Pollak, A. (2015) · Current Atherosclerosis Reports · doi:10.1007/s11883-015-0513-x · Cited by 16
Gene therapy in peripheral artery disease
Sanada, F., Taniyama, Y., Kanbara, Y., Otsu, R., Ikeda-Iwabu, Y., Carracedo, M., Rakugi, H., & Morishita, R. (2015) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2015.1007039 · Cited by 27
Nationales Register für die Erstlinientherapiestrategien bei Patienten mit kritischer Extremitätenischämie (CRITISCH-Register)
Bisdas, T., Stachmann, A., Weiss, K., Borowski, M., Grundmann, R., Torsello, G., & CRITISCH-Kollaborators, F. D. (2014) · Gefässchirurgie · doi:10.1007/s00772-014-1305-2 · Cited by 16
Outcomes from the REACH Registry for Australian general practice patients with or at high risk of atherothrombosis
Reid, C. M., Ademi, Z., Nelson, M. R., Connor, G., Chew, D. P., Shiel, L. M., Smeath, A., de Looze, F., Steg, P. G., Bhatt, D. L., et al. (2012) · The Medical Journal of Australia · doi:10.5694/mja11.10731 · Cited by 18
Prognostic value of a low post-exercise ankle brachial index as assessed by primary care physicians.
Diehm, C., Darius, H., Pittrow, D., Schwertfeger, M., Tepohl, G., Haberl, R., Allenberg, J., Burghaus, I., & Trampisch, H. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.11.030 · Cited by 16
“[8] Hirsch AT, Criqui MH, Treat-Jacobson D, et al.”
Background
Uninsured South Florida vascular surgery patients are less likely to receive optimal medical management than their insured counterparts.
Yeh, D.-M., Jones, M., Schulman, C., Karmacharya, J., & Velazquez, O. (2010) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2010.01.035 · Cited by 16
Peripheral artery disease and glaucoma: the singapore malay eye study.
Jeganathan, V., Wong, T., Foster, P., Crowston, J., Tay, W., Lim, S.-C., Saw, S., Tai, E., & Aung, T. (2009) · A M A Archives of Ophthalmology · doi:10.1001/archophthalmol.2009.136 · Cited by 16
Biological approaches to ischemic tissue repair: gene- and cell-based strategies
Roncalli, J. G., Tongers, J., Renault, M., & Losordo, D. W. (2008) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.6.5.653 · Cited by 15
Prevalencia de enfermedad arterial periférica estimada mediante el índice tobillo-brazo en pacientes con síndrome metabólico. Estudio MERITO I
Suárez, C., Manzano, L., Mostaza, J., Cairols, M., Palma, J. C., García, I., Acosta, A., Diodado, F., Comas, L., & Marco, J. M. (2007) · doi:10.1157/13102314 · Cited by 16
Symptoms of peripheral arterial disease: a critical review.
Olson, K. W., & Treat-Jacobson, D. (2004) · Journal of Vascular Nursing · doi:10.1016/j.jvn.2004.07.003 · Cited by 16
Diabetic Foot Ulcers: Evaluation and Management
Maderal, A. D., Vivas, A. C., Zwick, T. G., & Kirsner, R. S. (2012) · Hospital Practice · doi:10.3810/hp.2012.08.994 · Cited by 15
Increased Prevalence of Moderate and Severe Peripheral Arterial Disease in the American Indian (AI)/Alaskan Native (AN) Population; a Study of 96,000 AI/AN
Baxter, A. R., Jacobowitz, G. R., Guo, Y., Maldonado, T., Adelman, M. A., Berger, J. S., & Rockman, C. B. (2017) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2016.08.002 · Cited by 15
Stem Cell Therapy in Critical Limb Ischemia
Jeyaraman, M., Nagarajan, S., Maffulli, N., Packkyarathinam, R. P., Jeyaraman, N., Arulkumar, N., Khanna, M., Yadav, S., & Gupta, A. (2023) · Cureus · doi:10.7759/cureus.41772 · Cited by 16
“Critical limb ischemia (CLI) is a serious and potentially fatal form of peripheral artery disease (PAD), with low evidence of therapeutic success with the available treatment modalities [1,2].”
BackgroundInfluential
Critical Determinants of Chronic Limb Threatening Ischemia After Endovascular Treatment
Kim, W. (2022) · Korean Circulation Journal · doi:10.4070/kcj.2022.0064 · Cited by 15
Risk factors and consequences of graft infection after femoropopliteal bypass: A 25-year experience
Kim, Y., DeCarlo, C. S., Jessula, S., Latz, C. A., Chou, E. L., Patel, S. S., Majumdar, M., Mohapatra, A., & Dua, A. (2022) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2022.02.045 · Cited by 22
Plasmatic Magnesium Deficiency in 101 Outpatients Living with Type 2 Diabetes Mellitus
Zahra, H., Berriche, O., Mizouri, R., Boukhayatia, F., Khiari, M., Gamoudi, A., Lahmar, I., Amor, N. B., Mahjoub, F., Zayet, S., et al. (2021) · Clinics and Practice · doi:10.3390/clinpract11040095 · Cited by 15
Prevalence of Peripheral Arterial Disease and Associated Vascular Risk Factors in 65-Years-Old People of Northern Barcelona
Gonçalves-Martins, G., Gil-Sala, D., Tello-Díaz, C., Tenezaca-Sari, X., Marrero, C., Puig, T., Gayarre, R., Fité, J., & Bellmunt-Montoya, S. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10194467 · Cited by 15
“Despite the feasibility of this technique, this pathology is well known to be underdiagnosed and undertreated [4,5].”
Background
Retinal and choriocapillaris perfusion are associated with ankle-brachial-pressure-index and Fontaine stage in peripheral arterial disease
Wintergerst, M. W. M., Falahat, P., Holz, F., Schaefer, C., Finger, R., & Schahab, N. (2021) · Scientific Reports · doi:10.1038/s41598-021-90900-5 · Cited by 15
A Scoping Review of Vascular Surgery Education in the Medical School Curriculum.
Lee, K., Ng, J., & Choong, A. (2021) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2021.04.024 · Cited by 15
Similarities and differences in peripheral artery disease between China and Western countries
Gao, X., Tong, Z., Wu, Y., Guo, L., Gu, Y., & Dardik, A. (2021) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2021.03.030 · Cited by 16
Toe-brachial index and toe systolic blood pressure for the diagnosis of peripheral arterial disease
Tehan, P. E., Mills, J. L., Sebastian, M. G., Oldmeadow, C. J., & Chuter, V. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013783 · Cited by 3
Effects of Dual Antiplatelet Therapy on Graft Patency after Lower Extremity Bypass.
Belkin, N. L., Stoecker, J., Jackson, B., Damrauer, S., Glaser, J., Kalapatapu, V. R., Golden, M., & Wang, G. J. (2020) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2020.06.127 · Cited by 15
The Medical and Endovascular Treatment of PAD: A Review of the Guidelines and Pivotal Clinical Trials
Patel, R. A. G., Sakhuja, R., & White, C. J. (2018) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2018.09.004 · Cited by 18
Safety and efficacy of paclitaxel drug-coated balloon in femoropopliteal in-stent restenosis
Anantha-Narayanan, M., Love, K., Nagpal, S., Sheikh, A., Regan, C. J., & Mena-Hurtado, C. (2020) · Expert Review of Medical Devices · doi:10.1080/17434440.2020.1770593 · Cited by 15
Cardiovascular Long-term Outcome and Prophylactic Treatment Patterns in Peripheral Arterial Disease in a Population-based Cohort.
Sartipy, F., Lundin, F., Wahlberg, E., & Sigvant, B. (2019) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcz037 · Cited by 15
Intermittent Claudication in Physiotherapists' Practice
Spannbauer, A., Chwała, M., Ridan, T., Berwecki, A., Mika, P., Kulik, A., Berwecka, M., & Szewczyk, M. (2019) · BioMed Research International · doi:10.1155/2019/2470801 · Cited by 15
“According to the literature, only 18% of patients with claudication will require surgical intervention and 10% will be amputated in a 10-year follow-up, while mortality from infarcts and strokes at 5, 10, and 15 years will be 30%, 50%, and 70%, respectively [21].”
Background
The Influence of Socio-economic Deprivation on Mobility, Participation, and Quality of Life Following Major Lower Extremity Amputation in the West of Scotland.
Davie-Smith, F., Paul, L., Stuart, W., Kennon, B., Young, R., & Wyke, S. (2019) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2018.10.011 · Cited by 15
A Mixed Methods Study of Perceived Barriers to Physical Activity, Geriatric Syndromes and Physical Activity Levels among Older Adults with Peripheral Artery Disease and Diabetes
Whipple, M., Schorr, E. N., Talley, K. M. C., Lindquist, R., Bronas, U., & Treat-Jacobson, D. (2019) · Journal of Vascular Nursing · doi:10.1016/j.jvn.2019.02.001 · Cited by 15
“Diabetes is a significant risk factor for PAD, and estimates suggest that 20–30% of older adults with PAD have diabetes (Beks et al., 1995; Elhadd, Robb, Jung, Stonebridge, & Belch, 1999; Hirsch et al., 2001; Marso & Hiatt, 2006).”
Background
Experience Implementing Supervised Exercise Therapy for Peripheral Artery Disease
Salisbury, D., Whipple, M., Burt, M. A., Brown, R. J. L., Mays, R. J., Bakken, M., & Treat-Jacobson, D. (2019) · Journal of Clinical Exercise Physiology · doi:10.31189/2165-6193-8.1.1 · Cited by 15
“Patient education is an essential component of SET, particularly given the lack of awareness about PAD (37), and CMS requires that patients receive educational counseling at the time of referral to SET.”
Background
Medical Therapy in Peripheral Artery Disease and Critical Limb Ischemia
Foley, T. R., Waldo, S. W., & Armstrong, E. J. (2016) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-016-0464-8 · Cited by 16
Exercise ankle brachial index adds important prognostic information on long-term out-come only in patients with a normal resting ankle brachial index.
de Liefde, I. D., Klein, J., Bax, J. J., Verhagen, H., van Domburg, R., & Poldermans, D. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.10.051 · Cited by 15
After acute coronary syndrome, diabetic patients with peripheral vascular disease remain at high risk of cardiovascular events despite secondary prevention measures
Lafitte, M., Barandon, L., Pucheu, Y., Pillois, X., Gin, H., Bonnet, J., & Couffinhal, T. (2010) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2009.12.003 · Cited by 15
Management of Peripheral Arterial Disease of the Lower Extremities
Aronow, W. (2007) · Comprehensive therapy · doi:10.1007/s12019-007-8013-8 · Cited by 15
“The prevalence of PAD in 6,979 men and women, mean age 69 years, screened for PAD by an ABI because they were aged 70 years or older or because they were aged 50–69 years with a history of cigarette smoking or diabetes mellitus was 29% ( 10 ).”
Background
Unsupervised walking therapy and atherosclerotic risk-factor management for patients with peripheral arterial disease: A pilot trial
Collins, T. C., Johnson, S. L., & Souchek, J. (2007) · Annals of Behavioral Medicine · doi:10.1007/bf02879914 · Cited by 15
“Ironically, symptoms of intermittent claudication are present in 7% to 10% of patients with PAD (6, 7 ).”
Background
Magnetic resonance imaging of the peripheral vasculature.
Auerbach, E., & Martin, E. (2004) · American Heart Journal · doi:10.1016/j.ahj.2004.04.045 · Cited by 15
Management of intermittent claudication
Shearman, C. (2002) · British Journal of Surgery · doi:10.1046/j.1365-2168.2002.02084.x · Cited by 15
Automated oscillometric measurement of the ankle–brachial index in patients with coronary artery disease
Siński, M., Styczyński, G., & Szmigielski, C. A. (2012) · Hypertension Research · doi:10.1038/hr.2012.120 · Cited by 14
Association of inflammatory biomarkers with morbidity and mortality risk in patients with peripheral artery disease: a systematic review and meta-analysis
Fragão-Marques, M., Francisca-Marques, M., Rocha-Neves, J. P., & Özben, T. (2025) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408363.2025.2512472 · Cited by 12
“As a result, understanding the association between inflammatory biomarkers and clinical outcomes in PAD is crucial for risk stratification and targeted therapeutic interventions [3,72–74].”
Polyvascular Disease: A Narrative Review of Risk Factors, Clinical Outcomes and Treatment
Tannu, M., Hess, C. N., Gutierrez, J. A., Lópes, R. D., Swaminathan, R. V., Altin, S. E., & Rao, S. V. (2024) · Current Cardiology Reports · doi:10.1007/s11886-024-02063-0 · Cited by 15
A paradigm shift for cardiovascular outcome evaluation in diabetes: Major adverse cardiovascular events (MACE) to major adverse vascular events (MAVE)
Rastogi, A., Sudhayakumar, A., Schaper, N. C., & Jude, E. B. (2023) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2023.102875 · Cited by 14
Sex-Based Differences in Clinical Characteristics and Outcomes among Patients with Peripheral Artery Disease: A Retrospective Analysis
Dematteis, G., Biscetti, F., Polla, D. D. D., Serra, A., Burzo, M. L., Fuorlo, M., Nicolazzi, M., Novelli, A., Santoliquido, A., Gambassi, G., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12155094 · Cited by 14
“Consequently, PAD is both a common and critical medical condition that requires prompt diagnosis and management in ED [1,4].”
BackgroundInfluential
Underutilization of Medical Management of Peripheral Artery Disease Among Patients with Claudication Undergoing Lower Extremity Bypass.
Howard, R., Albright, J., Powell, C., Osborne, N., Corriere, M., Laveroni, E., Sukul, D., Goodney, P., & Henke, P. (2022) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2022.05.016 · Cited by 14
Atherectomy vs Other Modalities for Treatment During Peripheral Vascular Intervention
Chowdhury, M., & Secemsky, E. (2022) · Current Cardiology Reports · doi:10.1007/s11886-022-01709-1 · Cited by 14
“There are three peripheral intravascular lithotripsy catheters available: (1) Shockwave S4 which is available in sizes 2.”
Background
Safety and Effectiveness of Endovascular Therapy for the Treatment of Peripheral Artery Disease in Patients with and without Diabetes Mellitus
Korosoglou, G., Giuşcă, S., Langhoff, R., Lichtenberg, M. K. W., Lawall, H., Schellong, S., Stausberg, J., Hoffmann, U., Enders, D., & Malyar, N. M. (2022) · Angiology · doi:10.1177/00033197221075857 · Cited by 15
“In addition, the close associations between diabetes mellitus and PAD are widely recognized.(3,4) In the present study encompassing the so far largest population of all-comer patients with symptomatic PAD and DM, we could demonstrate that:”
Background
Performance of a clinical/proteomic panel to predict obstructive peripheral artery disease in patients with and without diabetes mellitus
McCarthy, C. P., Shrestha, S., Ibrahim, N. E., van Kimmenade, R. R. J., Gaggin, H. K., Mukai, R., Magaret, C. A., Barnes, G., Rhyne, R. F., Garasic, J. M., et al. (2019) · Open Heart · doi:10.1136/openhrt-2018-000955 · Cited by 17
“1136/openhrt-2018-000955 may prevent progression of disease.(4) The ankle-brachial index (ABI) is the most common non-invasive diagnostic modality used to detect the presence of lower extremity PAD; however, its accuracy is reduced in patients with stiff, calcified arteries.”
Background
Reversible Secretome and Signaling Defects in Diabetic Mesenchymal Stem Cells from Peripheral Arterial Disease Patients
Chadid, T., Morris, A., Surowiec, A., Robinson, S. T., Sasaki, M., Galipeau, J., Pollack, B., & Brewster, L. (2018) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2018.05.223 · Cited by 14
“population older than 65 years has PAD, but diabetic patients have an incidence of 30% by the age of 50 years.(2) In general, patients with PAD have a low overall incidence of major amputation, but this is not so in diabetes.”
Trends in Procedure Type, Morbidity and In-Hospital Outcomes of Patients with Peripheral Artery Disease: Data from the Brazilian Public Health System.
Nascimento, B., Brant, L., Lana, M. L. L., Lopes, E. L. V., & Ribeiro, A. (2016) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2015.08.019 · Cited by 14
Worse blood pressure control in patients with cerebrovascular or peripheral arterial disease compared with coronary artery disease
Mechtouff, L., Touzé, E., Steg, P. G., Ohman, E. M., Goto, S., Hirsch, A. T., Röther, J., Aichner, F., Weimar, C., Bhatt, D. L., et al. (2009) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02198.x · Cited by 14
Self-citation
Simvastatin and supplementation with ω-3 polyunsaturated fatty acids and vitamins improves claudication distance in a randomized PILOT study in patients with peripheral vascular disease
Carrero, J. J., López-Huertas, E., Salmerón, L. M., Ramos, V. E., Baró, L., & Ros, E. (2006) · Nutrition Research · doi:10.1016/j.nutres.2006.09.024 · Cited by 14
“However, several studies demonstrate how risk factors of this disease are often overlooked [5-7], emphasizing the need for specific guidelines for the management of these patients, as well as strategies to ensure their implementation.”
Background
Peripheral arterial disease in the catheterization laboratory: an underdetected and undertreated risk factor.
Bhatt, D. L. (2004) · Mayo Clinic proceedings · doi:10.4065/79.9.1107 · Cited by 14
PREVALENCE OF PERIPHERAL ARTERY DISEASE IN URBAN HIGH‐RISK MALAYSIAN PATIENTS
Amudha, K., Chee, K.-H., Tan, K., Tan, C. T., & Lang, C.-C. (2003) · International journal of clinical practice · doi:10.1111/j.1742-1241.2003.tb10509.x · Cited by 14
Epidemiology of Acute Critical Limb Ischemia
Knowles, M., & Timaran, C. (2017) · doi:10.1007/978-3-319-31991-9_1 · Cited by 14
Prevention and Management of Chronic Wounds
Salcido, R., Ahn, C., Wu, S. S., & Goldman, R. J. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-0884-4.10032-1 · Cited by 14
Anesthesia for Vascular Surgery
Norris, E. (2010) · Elsevier eBooks · doi:10.1016/b978-0-443-06959-8.00062-5 · Cited by 14
Physiological and Pathological Functions of Mammalian MicroRNAs
Liu, M., Jiang, S., Lu, Z., Li, Y., & Young, K. H. (2010) · Elsevier eBooks · doi:10.1016/b978-0-08-046884-6.00223-2 · Cited by 10
“Most of the miRNA genes have been discovered by direct cloning and sequencing of small RNA fractions extracted from cells and tissue samples (Hirsch et al. 2001).”
Background
Global burden of peripheral arterial disease and its risk factors, 1990–2021
Fu, M., & Zhang, H. (2025) · BMC Cardiovascular Disorders · doi:10.1186/s12872-025-05055-2 · Cited by 15
“This lack of awareness has contributed to underdiagnosis and inadequate treatment of PAD globally [3–6].”
Findings of a Novel Barbershop‐Based Peripheral Artery Disease Screening Program for Black Men
Solaru, K. W., Coy, T., Delozier, S., Brinza, E. K., Ravenell, J. E., Longenecker, C. T., Wright, J. T., & Gornik, H. L. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.122.026347 · Cited by 13
“4 In our study, participants with PAD also had significantly higher systolic BP, low-density lipoprotein cholesterol, and blood glucose than those without PAD, identifying opportunities for medical therapy and risk factor modification in this population.”
Comparative mortality according to peripheral artery disease and coronary heart disease/stroke in the United States
Matsushita, K., Gao, Y., Sang, Y., Ballew, S. H., Salameh, M., Allison, M., Selvin, E., & Coresh, J. (2022) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2022.04.029 · Cited by 15
Prevalence and Prognostic Significance of Polyvascular Disease in Patients Hospitalized With Acute Decompensated Heart Failure: The ARIC Study
Chunawala, Z. S., Qamar, A., Arora, S., Pandey, A., Fudim, M., Vaduganathan, M., Bhatt, D. L., Mentz, R. J., & Caughey, M. C. (2022) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2022.01.002 · Cited by 16
Risk stratification and mortality prediction in octo- and nonagenarians with peripheral artery disease: a retrospective analysis
Rammos, C., Kontogiannis, A., Mahabadi, A., Steinmetz, M., Messiha, D., Lortz, J., & Rassaf, T. (2021) · BMC Cardiovascular Disorders · doi:10.1186/s12872-021-02177-1 · Cited by 13
Medikamentöse Sekundärprävention bei Patienten mit peripherer arterieller Verschlusskrankheit
Gebauer, K., Wintersohl, K., Kraska, R., Kortendick, K., Fahrland, U., Freisinger, E., Meyborg, M., Stella, J., Engelbertz, C., Reinecke, H., et al. (2020) · Herz · doi:10.1007/s00059-020-04998-w · Cited by 13
Safety, effectiveness and mid-term follow-up in 136 consecutive patients with moderate to severely calcified lesions undergoing phoenix atherectomy
Giusca, S., Lichtenberg, M., Schueler, M., Heinrich, U., Eisenbach, C., Andrassy, M., & Korosoglou, G. (2020) · Heart and Vessels · doi:10.1007/s00380-020-01695-w · Cited by 13
“The health burden of peripheral artery disease is continuously rising [14].”
Background
Entering Cardiac Rehabilitation With Peripheral Artery Disease
Nguyen, C. H., Marzolini, S., Oh, P., & Thomas, S. G. (2020) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0000000000000475 · Cited by 13
The effect of lifestyle and risk factor modification on occlusive peripheral arterial disease outcomes: standard healthcare vs structured programme—for a randomised controlled trial protocol
Elfghi, M., Jordan, F., Dunne, D., Gibson, I., Jones, J. L., Flaherty, G. T., Sultan, S., & Tawfick, W. A. (2021) · Trials · doi:10.1186/s13063-021-05087-x · Cited by 14
Peripheral Arterial Disease
Hiatt, W. R., & Nehler, M. R. (2006) · Springer eBooks · doi:10.1007/0-387-22621-4_42 · Cited by 17
Ticagrelor and the Prevention of Microvascular Complications in Diabetes Patients with Lower Extremity Arterial Disease; Rationale and Design of the Hema-Kinesis Trial
Rosenson, R., Chen, Q., Najera, S. D., Lee, M. L., & Cho, D. (2018) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-018-6815-9 · Cited by 13
Systematic Review of Methods Used for the Microvascular Assessment of Peripheral Arterial Disease
Chen, Q., & Rosenson, R. (2018) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-018-6797-7 · Cited by 13
Innovative Informatics Approaches for Peripheral Artery Disease: Current State and Provider Survey of Strategies for Improving Guideline-Based Care
Chaudhry, A. P., Afzal, N., Abidian, M. M., Mallipeddi, V. P., Elayavilli, R. K., Scott, C. G., Kullo, I. J., Wennberg, P. W., Pankratz, J. J., Liu, H., et al. (2018) · Mayo Clinic Proceedings Innovations Quality & Outcomes · doi:10.1016/j.mayocpiqo.2018.02.001 · Cited by 13
“7,10 The emerging ﬁ eld of clinical informatics brings innovative approaches to investigate where discrepancies may exist between guideline recommendation and clinical care and may also provide solutions that mitigate gaps in practice.”
Prevalence and impact of critical limb ischaemia on in-hospital outcome in transcatheter aortic valve implantation in Germany.
Malyar, N., Kaier, K., Freisinger, E., Lüders, F., Kaleschke, G., Baumgartner, H., Frankenstein, L., Reinecke, H., & Reinöhl, J. (2017) · EuroIntervention · doi:10.4244/eij-d-17-00228 · Cited by 13
Attainment of low-density lipoprotein cholesterol goal after endovascular treatment is associated with reduced cardiovascular events in patients with peripheral arterial disease
Lee, J., Ko, Y., Shin, D., Kim, J., Kim, B., Choi, D., Hong, M., & Jang, Y. (2015) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2015.09.059 · Cited by 14
Relationship between a low ankle brachial index and all-cause death and cardiovascular events in subjects with and without diabetes.
Yokoyama, H., Sone, H., Honjo, J., Okizaki, S.-I., Yamada, D., Shudo, R., Shimizu, H., Moriya, T., & Haneda, M. (2014) · Journal of atherosclerosis and thrombosis · doi:10.5551/jat.22491 · Cited by 13
Epidemiologie und Behandlung der PAVK und der akuten Extremitätenischämie in deutschen Krankenhäusern von 2005 bis 2012
Eckstein, H., Knipfer, E., Trenner, M., Kuhnl, A., & Söllner, H. (2014) · Gefässchirurgie · doi:10.1007/s00772-013-1267-9 · Cited by 13
Cryoplasty for peripheral arterial disease.
McCaslin, J., Andras, A., & Stansby, G. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005507.pub3 · Cited by 13
Klinik und Poliklinik für Gefäßmedizin im Universitären Herzzentrum des Universitätsklinikums Hamburg-Eppendorf – das Hamburger Modell
Debus, E., Larena-Avellaneda, A., Ivoghli, A., Tató, F., Meinertz, T., & Reichenspurner, H. (2010) · Gefässchirurgie · doi:10.1007/s00772-010-0784-z · Cited by 13
Aspirin and secondary prevention in peripheral artery disease: a perspective for the early 21st century.
McDermott, M., & Criqui, M. (2009) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.2009.668 · Cited by 13
Peripheral arterial disease and its clinical significance in nonagenarians
Suominen, V., Rantanen, T., Heikkinen, E., Venermo, M., & Salenius, J. (2008) · Aging Clinical and Experimental Research · doi:10.1007/bf03324767 · Cited by 13
Glycemic Control, Lipid-Lowering Treatment, and Prognosis in Diabetic Patients with Peripheral Atherosclerotic Disease
Feringa, H. H. H., Karagiannis, S. E., Vidaković, R., Elhendy, A., Schouten, O., Boersma, E. H., Bax, J. J., & Poldermans, D. (2007) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2007.04.004 · Cited by 14
Peripheral arterial disease is only the tip of the atherosclerotic "iceberg".
Futterman, L., & Lemberg, L. (2002) · American Journal of Critical Care · doi:10.4037/ajcc2002.11.4.390 · Cited by 13
Polyvascular Disease: Definition, Epidemiology, and Relevance
Aboyans, V. (2014) · Springer eBooks · doi:10.1007/978-3-642-37393-0_213-1 · Cited by 9

Authors: Hirsch, A. T.
Affiliations: University of Minnesota (US)
Corresponding author: Hirsch, Alan T.
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 2001-09-19
Volume: 286
Issue: 11
Pages: 1317
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.286.11.1317
OpenAlex: W2140136269
Cited by: 2,835
References: 0
Citations by year: 2026: 59 · 2025: 77 · 2024: 89 · 2023: 102 · 2022: 113 · 2021: 127 · 2020: 100 · 2019: 105 · 2018: 147 · 2017: 105 · 2016: 135 · 2015: 122 · 2014: 160 · 2013: 145 · 2012: 166
FWCI: 62.22
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5k07hl003435-05)
National Heart, Lung, and Blood Institute (1-K07-HL03435-01)
Topics: Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetic Foot Ulcer Assessment and Management
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Vascular Procedures and Complications
Keywords: peripheral arterial disease, ankle-brachial index, underdiagnosis, patient awareness, physician awareness, cardiovascular disease, atherosclerosis, antiplatelet therapy, smoking cessation, diabetes mellitus, intermittent claudication, primary care, older adults, limb revascularization, cardiovascular risk stratification, diabetes self-management education
MeSH terms: Aged, Arteriosclerosis, Cardiovascular Diseases, Cross-Sectional Studies, Family Practice, Female, Humans, Intermittent Claudication, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Platelet Aggregation Inhibitors, Risk Factors, Ultrasonography, Doppler

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Peripheral Arterial Disease Detection, Awareness, and Treatment in Primary Care

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Metadata

Record

About these checks