Cited by 2,835Peripheral Artery Disease ManagementDiabetic Foot Ulcer Assessment and ManagementVascular Procedures and Complications

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Peripheral Arterial Disease Detection, Awareness, and Treatment in Primary Care

Hirsch, Alan T.·2001·JAMA

DOI 10.1001/jama.286.11.1317

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Abstract

Context Peripheral arterial disease (PAD) is a manifestation of systemic atherosclerosis that is common and is associated with an increased risk of death and ischemic events, yet may be underdiagnosed in primary care practice. Objective To assess the feasibility of detecting PAD in primary care clinics, patient and physician awareness of PAD, and intensity of risk factor treatment and use of antiplatelet therapies in primary care clinics. Design and setting The PAD Awareness, Risk, and Treatment: New Resources for Survival (PARTNERS) program, a multicenter, cross-sectional study conducted at 27 sites in 25 cities and 350 primary care practices throughout the United States in June-October 1999. Patients A total of 6979 patients aged 70 years or older or aged 50 through 69 years with history of cigarette smoking or diabetes were evaluated by history and by measurement of the ankle-brachial index (ABI). PAD was considered present if the ABI was 0.90 or less, if it was documented in the medical record, or if there was a history of limb revascularization. Cardiovascular disease (CVD) was defined as a history of atherosclerotic coronary, cerebral, or abdominal aortic aneurysmal disease. Main outcome measures Frequency of detection of PAD; physician and patient awareness of PAD diagnosis; treatment intensity in PAD patients compared with treatment of other forms of CVD and with patients without clinical evidence of atherosclerosis. Results PAD was detected in 1865 patients (29%); 82…

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“Introduction Lower extremity PAD is a highly prevalent atherosclerotic disease that affects more than 230 million individuals worldwide [1] and is associated with significant morbidity [2], mortality [3], and economic burden [4–6].”
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“Moreover, cardiovascular disease is more prevalent in NIU patients with PAD as both share similar atherosclerosis risk factor profiles(14); even after adjustment for known atherosclerosis-related risk factors, patients with PAD were still prospectively associated with higher risk of all-cause mortality compared with t…”
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BackgroundMethodInfluential
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Peripheral Artery Disease
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“Student10 has mixed behavior like in [34].”
Retracted
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“The mean age was 60 (53–66) years, and the mean diabetes duration was 11 (6-17) years.”
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Level of Disease and Association with Health Status in Patients Presenting with Claudication from the PORTRAIT Registry.
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“During follow-up, clinical PAD was identified by self-report of a PAD diagnosis by the participant at (1) MESA clinic visits, (2) follow-up phone call, or (3) participant notification.”
BackgroundMethod
Negotiating commissioning pathways for the successful implementation of innovative health technology in primary care
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“com considered as an earlier stage of PAD compared with chronic limb ischemia (CLI).(20,21) Our study indicates that utilization of LEB for claudication significantly increased in states that expanded Medicaid in 2014 compared with those that did not.”
Result
Peripheral Arterial Disease: Supervised Exercise Therapy Through Cardiac Rehabilitation.
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“Cooccurrence of PAD and DM reaches more than 30% [17].”
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New Curveball for Hypertension Guidelines?
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Statins in PAD: What are we waiting for?
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Association between health status and sociodemographic, clinical and treatment disparities in the Patient-centered Outcomes Related to TReatment Practices in Peripheral Arterial Disease: Investigating Trajectories (PORTRAIT) registry
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Authors: Hirsch, A. T.
Affiliations: University of Minnesota (US)
Corresponding author: Hirsch, Alan T.
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 2001-09-19
Volume: 286
Issue: 11
Pages: 1317
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.286.11.1317
OpenAlex: W2140136269
Cited by: 2,835
References: 0
Citations by year: 2026: 59 · 2025: 77 · 2024: 89 · 2023: 102 · 2022: 113 · 2021: 127 · 2020: 100 · 2019: 105 · 2018: 147 · 2017: 105 · 2016: 135 · 2015: 122 · 2014: 160 · 2013: 145 · 2012: 166
FWCI: 62.22
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5k07hl003435-05)
National Heart, Lung, and Blood Institute (1-K07-HL03435-01)
Topics: Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetic Foot Ulcer Assessment and Management
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Vascular Procedures and Complications
Keywords: peripheral arterial disease, ankle-brachial index, underdiagnosis, patient awareness, physician awareness, cardiovascular disease, atherosclerosis, antiplatelet therapy, smoking cessation, diabetes mellitus, intermittent claudication, primary care, older adults, limb revascularization, cardiovascular risk stratification, diabetes self-management education
MeSH terms: Aged, Arteriosclerosis, Cardiovascular Diseases, Cross-Sectional Studies, Family Practice, Female, Humans, Intermittent Claudication, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Platelet Aggregation Inhibitors, Risk Factors, Ultrasonography, Doppler

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Peripheral Arterial Disease Detection, Awareness, and Treatment in Primary Care

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