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Sex and Race Differences in the Association Between Statin Use and the Incidence of Alzheimer Disease
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Long-term statin usage correlates with reduced AD incidence in some human studies.
“In humans, long-term statin usage has been shown to correlate with reduced AD incidence in some studies (Shepardson et al., 2011a, Shepardson et al., 2011b, Zissimopoulos et al., 2017), although the underlying mechanisms have been debated.”
From Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons (2019) · cites this paper as Zissimopoulos et al., 2017
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Cites
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A systemic view of Alzheimer disease — insights from amyloid-β metabolism beyond the brain
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Impact of Statin Use on Dementia Incidence in Elderly Men and Women with Ischemic Heart Disease
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Metadata
- Authors
- Zissimopoulos, J. M., Barthold, D., Brinton, R. D., & Joyce, G.
- Affiliations
- Leonard D. Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles
- Leonard D. Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles2Center for Innovation in Brain Science, University of Arizona Health Sciences, Tucson
- Venue
- JAMA Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 2017-02-01
- Volume
- 74
- Issue
- 2
- Pages
- 225
- ISSN
- 2168-6149
- PMC
- PMC5646357
- Cited by
- 163
- References
- 2
- Language
- en
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