The DOI matches its Crossref record; 69 of the 71 references it cites were found in a registry or an index.
Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue: A Meta-analysis
Open accessAbstract
IMPORTANCE: Cancer-related fatigue (CRF) remains one of the most prevalent and troublesome adverse events experienced by patients with cancer during and after therapy. OBJECTIVE: To perform a meta-analysis to establish and compare the mean weighted effect sizes (WESs) of the 4 most commonly recommended treatments for CRF-exercise, psychological, combined exercise and psychological, and pharmaceutical-and to identify independent variables associated with treatment effectiveness. DATA SOURCES: PubMed, PsycINFO, CINAHL, EMBASE, and the Cochrane Library were searched from the inception of each database to May 31, 2016. STUDY SELECTION: Randomized clinical trials in adults with cancer were selected. Inclusion criteria consisted of CRF severity as an outcome and testing of exercise, psychological, exercise plus psychological, or pharmaceutical interventions. DATA EXTRACTION AND SYNTHESIS: Studies were independently reviewed by 12 raters in 3 groups using a systematic and blinded process for reconciling disagreement. Effect sizes (Cohen d) were calculated and inversely weighted by SE. MAIN OUTCOMES AND MEASURES: Severity of CRF was the primary outcome. Study quality was assessed using a modified 12-item version of the Physiotherapy Evidence-Based Database scale (range, 0-12, with 12 indicating best quality). RESULTS: From 17 033 references, 113 unique studies articles (11 525 unique participants; 78% female; mean age, 54 [range, 35-72] years) published from January 1, 1999, through May 31, 2016, had sufficient data. Studies were of good quality (mean Physiotherapy Evidence-Based Database scale score, 8.2; range, 5-12) with no evidence of publication bias. Exercise (WES, 0.30; 95% CI, 0.25-0.36; P < .001), psychological (WES, 0.27; 95% CI, 0.21-0.33; P < .001), and exercise plus psychological interventions (WES, 0.26; 95% CI, 0.13-0.38; P < .001) improved CRF during and after primary treatment, whereas pharmaceutical interventions did not (WES, 0.09; 95% CI, 0.00-0.19; P = .05). Results also suggest that CRF treatment effectiveness was associated with cancer stage, baseline treatment status, experimental treatment format, experimental treatment delivery mode, psychological mode, type of control condition, use of intention-to-treat analysis, and fatigue measures (WES range, -0.91 to 0.99). Results suggest that the effectiveness of behavioral interventions, specifically exercise and psychological interventions, is not attributable to time, attention, and education, and specific intervention modes may be more effective for treating CRF at different points in the cancer treatment trajectory (WES range, 0.09-0.22). CONCLUSIONS AND RELEVANCE: Exercise and psychological interventions are effective for reducing CRF during and after cancer treatment, and they are significantly better than the available pharmaceutical options. Clinicians should prescribe exercise or psychological interventions as first-line treatments for CRF.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source doesn’t support the claim as written.
In the citing paper
“fewer than 10% of prior interventions targeting cancer-related fatigue have included patients with metastatic disease [42].”
From Pilot randomized trial of an acceptance-based telehealth intervention for women with ovarian cancer and PARP inhibitor-related fatigue (2023) · cites this paper as [42]
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Existing behavioral symptom management interventions for cancer survivors have been primarily developed and tested among older cancer survivors (aged > 40) [27–32].”
From Improving symptom management for survivors of young adult cancer: rationale and study protocol for a pilot randomized controlled trial (2024) · cites this paper as [29]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“prior exercise and psychosocial interventions for cancer-related fatigue have beenlong and demanding, requiring an average of 43 one-hour sessions [42]”
From Pilot randomized trial of an acceptance-based telehealth intervention for women with ovarian cancer and PARP inhibitor-related fatigue (2023) · cites this paper as [42]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Physical activity training has proven effective and is recommended in guidelines for treating CRF.10,42”
From Exploring the dynamic interconnectedness of protective and perpetuating factors of cancer-related fatigue (2023) · cites this paper as [42]
The cited source says what the claim attributes to it.
In the citing paper
“the few studies that have included patients with advanced cancers have demonstrated smaller effect sizes compared with early-stage cancers [42].”
From Pilot randomized trial of an acceptance-based telehealth intervention for women with ovarian cancer and PARP inhibitor-related fatigue (2023) · cites this paper as [42]
The cited source says what the claim attributes to it.
In the citing paper
“Patients are also recommended various forms of psychotherapy [10,11,12], such as relaxation and guided imagery [13,14], mindfulness meditation (mindfulness-based stress reduction) [14], music therapy [15,16], occupational therapy [17,18,19], and breathing exercises [20,21,22].”
From The Effect of Vinyasa Yoga Practice on the Well-Being of Breast-Cancer Patients during COVID-19 Pandemic (2023) · cites this paper as [11]
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“The basis for screening and intervention is the National Comprehensive Cancer Network guideline on fatigue [38–42].”
From The BrEasT cancer afTER-CARE (BETTER-CARE) programme to improve breast cancer follow-up: design and feasibility study results of a cluster-randomised complex intervention trial (2024) · cites this paper as [39]
Experimental — accuracy not yet measuredIn the citing paper
“The effect of exercise was strongest for moderate to vigorous intensity exercise whereas the effect for low intensity training was weak and this level of exercise is unlikely to reduce fatigue(22, 24, 26, 28).”
From Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable (2019) · cites this paper as [26]
In the citing paper
“Moderate intensity combined aerobic plus resistance training sessions performed 2–3 times per week or twice weekly moderate intensity resistance training may also be effective(21, 24–26), and the latter particularly in prostate cancer(27).”
From Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable (2019) · cites this paper as [26]
In the citing paper
“The effect of exercise was strongest for moderate to vigorous intensity exercise whereas the effect for low intensity training was weak and this level of exercise is unlikely to reduce fatigue(22, 24, 26, 28).”
From Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable (2019) · cites this paper as [26]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554
Conducting Meta-Analyses in R with the metafor Package
Viechtbauer, W. (2010) · Journal of Statistical Software · doi:10.18637/jss.v036.i03 · Cited by 20,464
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.005 · Cited by 19,575
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2009) · doi:10.1002/9780470743386 · Cited by 14,225
CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
the CONSORT Group, Schulz, K. F., Altman, D. G., & Moher, D. (2010) · BMC Medicine · doi:10.1186/1741-7015-8-18 · Cited by 13,371
Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2021) · doi:10.1002/9781119558378 · Cited by 9,799
Verhagen, A. P., de Vet, H. C. W., de Bie, R. A., Kessels, A. G. H., Boers, M., Bouter, L. M., & Knipschild, P. G. (1998) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(98)00131-0 · Cited by 2,470
Publication Bias in Meta‐Analysis: Prevention, Assessment and Adjustments
(2005) · doi:10.1002/0470870168 · Cited by 2,368
Research works printed but not linked: 1
- [46]Higgins JPT Green S Cochrane Collaboration: Cochrane Handbook for Systematic Reviews of Interventions Hoboken, NJ Wiley-Blackwell 2008
Cited by
Sorted by citations
Items 701–800 of 932
Geheilt, aber nicht gesund: Das Problem der Langzeitnebenwirkungen
Horneber, M., Lüftner, D., & Pister, R. (2019) · Oncology Research and Treatment · doi:10.1159/000500817
Otto, S., de Gregorio, N., Volz, S., Janni, W., de Gregorio, A., Steinacker, J. M., & Ebner, F. K. (2019) · B&G Bewegungstherapie und Gesundheitssport · doi:10.1055/a-9056-1133
Cohen, J. D., & Mullen, S. P. (2019) · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign) · doi:10.17605/osf.io/xkv6t
Adaptation psychologique au diagnostic et aux traitements
Razavi, D., Lewis, F., Hertay, A., Delvaux, N., & Farvacques, C. (2019) · Elsevier eBooks · doi:10.1016/b978-2-294-75811-9.00005-2
Advanced Cancers, Metastatic Disease, and Palliative Care
Lowe, S. S., Sellar, C. M., Suderman, K., & McNeely, M. L. (2020) · Springer eBooks · doi:10.1007/978-3-030-42011-6_16
Metastatic Bladder Cancer and the Use of Cisplatin Chemotherapy
Mille, P. J., & Carsello, J. (2020) · Springer eBooks · doi:10.1007/978-3-030-52021-2_16
Die Rolle von bewegungstherapeutischen Therapiekonzepten
Siebert, S., & Baumann, F. T. (2020) · InFo Hämatologie + Onkologie · doi:10.1007/s15004-020-8280-4
Leben nach Krebs: Gezielte Bewegungstherapie bei einer chronischen Fatigue
Siebert, S., Baumann, F. T., & Salchow, J. L. (2021) · Deutsche Zeitschrift für Onkologie · doi:10.1055/a-1386-2436
Sierra-Murguía, M. A., González-Alcocer, L. D. C., Contreras, G. N., Guevara-Sanginés, M. L., & Blázquez, F. P. (2021) · Psicooncología · doi:10.5209/psic.74533 · Cited by 1
Féger, C., & Petitjean, F. (2021) · HEGEL - HEpato-GastroEntérologie Libérale · doi:10.3917/heg.112.0119
Wagoner, C. W. (2021) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/eb1f-6z43
Hauth, F., & Gani, C. (2021) · Forum · doi:10.1007/s12312-021-01023-x
Sport als Prävention und Therapie bei Krebs
Götte, M., & Kesting, S. (2021) · Elsevier eBooks · doi:10.1016/b978-3-437-23461-3.00032-8
Luo, X., Xie, Q., Shi, Q., Miao, Y., Yu, Q., Yu, H., Yin, H. X., Leng, X., Han, Y., & Zhou, H. (2021) · Research Square · doi:10.21203/rs.3.rs-593275/v1
Sun, X., Chen, Y., Cheung, W. K. W., Wu, X., Xiao, F., & Chung, V. C. (2021) · doi:10.2196/preprints.29231
Effects of a Physical Exercise Program in Quality of Life of Breast Cancer Survivors
(2019) · Case Medical Research · doi:10.31525/ct1-nct04024280
Bucio, D., & Bertram, J. J. (2022) · Rehabilitation Oncology · doi:10.1097/01.reo.0000000000000295
Ausdauersport als Rehabilitationsmaßnahme bei Krebs
Mathias, D. (2022) · Springer eBooks · doi:10.1007/978-3-662-64209-2_76
Rüffer, J. U., Horneber, M., & Schwarz, R. (2020) · Springer Reference Medizin · doi:10.1007/978-3-662-46764-0_90-1
Yennurajalingam, S., & Bruera, E. D. (2021) · Oxford University Press eBooks · doi:10.1093/med/9780198821328.003.0066
Bartolo, M. (2019) · Springer eBooks · doi:10.1007/978-3-319-95684-8_1
Kiemeney, L. A. L. M., Assendelft, W. J., Vrieling, A., de Bruin, M., & Buffart, L. M. (2020) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-2449-1_42
Albert, Y., Bien, J., Blum, D., van Caster, P., Coym, A., Doll, A., Eisenmann, Y., Glahn, S., Goldbach, S., Hlawatsch, C., et al. (2019) · Elsevier eBooks · doi:10.1016/b978-3-437-15315-0.00002-4
The Role of Diet, Physical Activity, and Body Composition in Cancer Prevention
Thomson, C. A., & Bea, J. W. (2019) · Springer eBooks · doi:10.1007/978-3-030-15935-1_4
荒金, 英. (2018) · The Japanese Journal of SURGICAL METABOLISM and NUTRITION · doi:10.11638/jssmn.52.6_317
Follow-up Guidelines, Evidence, and Recommendations
Kimman, M., van Hezewijk, M., & Boersma, L. J. (2022) · Springer eBooks · doi:10.1007/978-3-030-91170-6_30
Ali, D. (2022) · Queensland University of Technology · doi:10.5204/thesis.eprints.233465
Zimmerman, C. S., Temereanca, S., Daniels, D. S., Penner, C., Cannonier, T., Jones, S. R., & Kerr, C. E. (2022) · medRxiv · doi:10.1101/2022.08.18.22278965
Future Directions in the Management of Non–Small Cell Lung Cancer Harboring Driver Mutations
Herbst, R. S. (2022) · ONCOLOGY · doi:10.46883/2022.25920974
Palliative care and quality of life
Chase, D. M., Satero, J., Wenzel, L. B., & Monk, B. J. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-77684-4.00028-3
Nursing management of fatigue in cancer patients
Machálková, L., Štureková, L., & Ročková, Š. (2022) · Onkologie · doi:10.36290/xon.2022.053
Sarcopenia and Physical Performance in Patients with Cancer
Tanaka, S., & Tatematsu, N. (2022) · Springer eBooks · doi:10.1007/978-981-19-6710-8_23
Wei, H., Sun, Y., He, J., Liu, J.-W., Xie, K., Zheng, Y., & Zhu, J. (2023) · PubMed Central · doi:10.12182/20230160109
Wiskemann, J. (2022) · Springer eBooks · doi:10.1007/978-3-662-64257-3_11
Shambhavi, S., & Lobo, D. (2022) · Journal of Complementary and Alternative Medical Research · doi:10.9734/jocamr/2022/v20i4422
Hofmann, H. (2023) · PiD - Psychotherapie im Dialog · doi:10.1055/a-1817-9267
Ralec, C., Creff, L., Verdun, S., Buyse, M., & Bouée, J.-B. (2023) · Movement & Sport Sciences - Science & Motricité · doi:10.1051/sm/2022029
Sport- und Bewegungstherapie in der Onkologie
Wefelnberg, M. M., Baumann, F. T., & Schmidt, T. (2023) · Springer Reference Medizin · doi:10.1007/978-3-662-46764-0_346-1
Popp, B., Bressler, T., Schmitz, S., & Donahue, B. R. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-87688-9.00036-2
Functional Capacity in Cardiotoxicity: Effects of Physical Exercise
Rodrigues, A. G., & Trindade, A. C. (2022) · ABC Heart Failure & Cardiomyopathy · doi:10.36660/abchf.20220089
Behandlung der tumorassoziierten Fatigue in der Rehabilitation
Baumann, F. T., Horneber, M., & Weis, J. (2023) · Springer Reference Medizin · doi:10.1007/978-3-662-46764-0_317-1
Intervensi Latihan Tai-Chi pada Pasien Kanker yang Mengalami Fatigue
Ramadhana, A., & Gayatri, D. (2023) · Jurnal Keperawatan Silampari · doi:10.31539/jks.v6i2.5675
Serrano, L. (2023) · La Presse Médicale Formation · doi:10.1016/j.lpmfor.2023.10.020
Tumorkachexie: die Bedeutung von Ernährung und Bewegung in der Onkologie
Zopf, Y., Herrmann, H. J., Reljic, D., & Hardt, L. (2023) · Zeitschrift für Komplementärmedizin · doi:10.1055/a-2188-3671
Otto, S., Horneber, M., & Weis, J. (2023) · Springer eBooks · doi:10.1007/978-3-662-64615-1_4
INGETROKKEN HOOFDSTUK: Vermoeidheid
van der Lee, M. L., & van den Brink, M. J. (2024) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-2853-6_4
Early Survivorship: Rehabilitation and Reintegration
Kechagioglou, P., & Fuller-Shavel, N. (2023) · Springer eBooks · doi:10.1007/978-3-031-51216-2_14 · Cited by 1
Integrative Oncology Matters: Building the Foundations
Kechagioglou, P., & Fuller-Shavel, N. (2023) · Springer eBooks · doi:10.1007/978-3-031-51216-2_4
Palliativmedizinische Behandlung von gynäkologischen Malignomen und Mammakarzinomen
Schubert, M., Korff, N., Rieke, K., Bauerschlag, D., & Brügge, S. (2024) · Die Gynäkologie · doi:10.1007/s00129-024-05208-y
Javid, M., Maredpour, A., & MALEKZADEH, M. H. (2023) · Armaghane Danesh · doi:10.61186/armaghanj.28.6.6
van der Lee, M. L., & van den Brink, M. J. (2024) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-368-3023-2_5
Physical Therapy for Patients With Breast Cancer
Waltke, L. J. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-93249-3.00011-4
Palliative Care for Geriatric Psychiatric Patients with Life-Limiting Illness
Leung, M. W., Santo, E. C., Kaplan, L. E., & Bourgeois, J. A. (2024) · Springer eBooks · doi:10.1007/978-3-031-47802-4_31
Physical, Psychological/Psychiatric, Social, and Spiritual Problems and Symptoms
Siddall, P. J., & MacLeod, R. (2024) · Springer eBooks · doi:10.1007/978-3-319-31738-0_9-2
Önal, G., & Yılmaz, G. G. (2024) · Interdisciplinary cancer research · doi:10.1007/16833_2024_319
Karšaj, J. M., Brnić, V., & Brnić, S. (2024) · Liječnički vjesnik · doi:10.26800/lv-146-5-6-4
Smuszkiewicz-Różański, P., Różańska-Smuszkiewicz, G., Ragan, D., Długosz, J., Staszczak, P., Bara, M., Kmiotek, W., Jaworska, B., Oronowicz, R., & Jama, G. (2024) · Quality in Sport · doi:10.12775/qs.2024.20.53434
Jung, M. W., Schubert, P., Stephenson, A., & Bader, P. (2024) · Physiotherapy Quarterly · doi:10.5114/pq/174936
A Fact-Finding Survey of the Concerns of Patients with Cancer: A Network AnalysisPreprint
Yamamoto, K., Tanabe, Y., Nonogaki, K., Okumura, H., Ozaki, H., Kuno, M., Watanabe, S., Takemura, K., Yamanaka, T., Kizawa, R., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4849633/v1
Emerging trends in oncology: a comprehensive literature review
Eskandar, K. (2024) · Surgery and Oncology · doi:10.17650/2949-5857-2024-14-3-59-68
Multisymptom Burden in Cancer Survivors: Benefits of Physical Activity
Cardaci, T. D., VanderVeen, B. N., Bullard, B. M., Carson, J. A., & Murphy, E. A. (2024) · Exercise Sport and Movement · doi:10.1249/esm.0000000000000029
Exercise and Sports in Cancer Patients
Gerçek, H. (2024) · doi:10.69860/nobel.9786053358893.5
Ensuring Functional Recovery After Radiothrapy
Düzova, M. (2024) · doi:10.69860/nobel.9786053358893.3
Muench, A., Lampe, E. W., Garland, S. N., Dhaliwal, S. S., & Perlis, M. L. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-08930-4
Exercise in Breast Cancer: A Key Factor for the Management of Side Effects of Breast Cancer
Kaya, G., & Tuğral, A. (2024) · Springer eBooks · doi:10.1007/978-3-031-75480-7_17
Patra, B., & Mishra, S. (2024) · Springer eBooks · doi:10.1007/978-981-97-7755-6_47
Leben mit krebsassoziierter Fatigue
Wagner, A. S., Schmidt, M. E., Blickle, P., Jentschke, E., Steindorf, K., & Maatouk, I. (2025) · Die Onkologie · doi:10.1007/s00761-025-01692-6
(2025) · Elsevier eBooks · doi:10.1016/b978-3-437-21835-4.00116-5
Antonen, E. M., Nadler, M. B., Langelier, D. M., Campbell, K. L., Flamer, D., Cho, J. H., Capozza, S. J., Avery, L. M., Bland, K. A., Leatherdale, S. T., et al. (2025) · PLoS ONE · doi:10.1371/journal.pone.0322371
Prevalence of Cancer-Related Fatigue: A Prospective Observational Study
Reddy, P. K., Rajkumar, B., Shrivastava, S. P., Soumya, P., Divya, B., Anvesh, R., Bhavani, B. N., Gouthami, G., Niharika, K., & Bhatnagar, S. (2025) · South Asian Journal of Cancer · doi:10.1055/s-0045-1808237
Kleckner, A. S., Mocci, E., Clingan, C. L., Youngblood, S. M., Rosenblatt, P., Tkaczuk, K. H. R., Kleckner, I. R., & Dorsey, S. G. (2025) · European Journal of Cancer Care · doi:10.1155/ecc/1092518
Self-citationYajima, S., Kobayashi, S., Hashimoto, T., Nakamura, Y., Yamashita, R., Misumi, T., Sakamoto, Y., Horasawa, S., Fujisawa, T., Imai, M., et al. (2025) · International Journal of Clinical Oncology · doi:10.1007/s10147-025-02798-y
Wu, Q., Su, C., Xing, M., & Ouyang, L. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1497151
Ghosh, S., Siddique, M., Chatterjee, K., Pal, R. K., Alam, S. M., Halder, I., Chandra, S., Midya, A., & Saha, S. (2025) · Homeopathy · doi:10.1055/a-2547-9741
Bøhn, S., Reinertsen, K. V., Kiserud, C. E., Loge, J. H., Fosså, A., Skaali, T., Blomhoff, R., Oldervoll, L. M., Courneya, K. S., Raastad, T., et al. (2025) · JMIR Research Protocols · doi:10.2196/69336
Huda, N., Gautama, M. S. N., Dewi, W. N., Waluyo, A. D., Chang, H., & Shaw, M. K. (2025) · Journal of Nursing Scholarship · doi:10.1111/jnu.70031
Huizinga, F., Westerink, N.-D. L., Walenkamp, A., Berendsen, A. J., Berger, M. Y., & Brandenbarg, D. (2025) · Translational Behavioral Medicine · doi:10.1093/tbm/ibaf029
Manisundaram, N. V., Portuondo, J. I., Chen, C. G., Bloomston, M., Schmidt, C. R., Zyromski, N. J., Ball, C. G., Morgan, K. A., Hughes, S. J., Karanicolas, P. J., et al. (2025) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2025.116523
Chiu, H., Zhuang, S. R., Shen, Y., Thangaleela, S., & Wang, C. (2025) · Nutrients · doi:10.3390/nu17152433
Meier, S.-F. (2025) · Elsevier eBooks · doi:10.1016/b978-3-437-45117-1.00011-3
Zhang, M., & Liu, X. (2025) · Research Square · doi:10.21203/rs.3.rs-6932631/v1
Kiemeney, L. A. L. M., Assendelft, W. J., Vrieling, A., de Bruin, M., & Buffart, L. M. (2025) · doi:10.1007/978-90-368-3138-3_39
Wilson, C., Pickering, K., Wane, S., Cohen, J., Huang, C., Northgraves, M. J., Crank, H., Anderson, A. R. A., Cain, H. J., Copeland, R. J., et al. (2025) · Pilot and Feasibility Studies · doi:10.1186/s40814-025-01689-3
Pichel, R. C., Soares‐Miranda, L., Miranda, H. M., Vale, S. M. C. G., Coelho, J. Q., Guerra, L. P., Braga, M. M., Pinhol, G., Fidalgo, P., Araújo, A., et al. (2025) · Supportive Care in Cancer · doi:10.1007/s00520-025-09824-9 · Cited by 1
Carpenter, K. M., Conroy, K., Black, L. L., Salani, R., & Lustberg, M. B. (2025) · Supportive Care in Cancer · doi:10.1007/s00520-025-09858-z · Cited by 1
Relationship of Resilience With Fatigue and Quality of Life in Uro‐Oncological Surgery
Sakarya, R., & Yılmaz, M. (2025) · International Journal of Urological Nursing · doi:10.1111/ijun.70033
Bécourt, S., Abadie‐Lacourtoisie, S., Calvat, T., Coudurier-Curveur, I., Fiteni, F., Méry, B., Meynard, G., Scotté, F., Vaflard, P., & Zelek, L. H. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1617600
Physical activity levels of women with breast cancer during treatment: a case-control study
Silva, N. P., Marques, V. A., Ferreira‐Júnior, J. B., & Vieira, C. A. (2025) · Revista Brasileira de Atividade Física & Saúde · doi:10.12820/rbafs.30e0406
Timm, E., Berlowitz, I., & Wolf, U. (2025) · The Oncologist · doi:10.1093/oncolo/oyaf343
Symptom Management for Older Adults with Pulmonary Disease
Spathis, A., & Donesky, D. (2025) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2025.07.007
Hiensch, A. E., Müller, J., Zopf, E. M., Schmidt, M. E., Monninkhof, E. M., Trevaskis, M., Belloso, J., Clauss, D., Gunasekara, N., Joaquim, A. V., et al. (2025) · Trials · doi:10.1186/s13063-025-09263-1
Pelzer, F., Loef, M., Martin, D. D., & Baumgartner, S. (2022) · Zeitschrift für Phytotherapie · doi:10.1055/s-0042-1749298
Righes, S., Waroquier, P., Caillier, M., Verkaeren, O., Kristanto, P., & Merckaert, I. (2025) · European Journal of Cancer Care · doi:10.1155/ecc/6659905
Zhang, L., Fang, H., Zhang, Y., Su, X., Zhang, J., He, L., Bo, C., Yan, Y., Liu, J., & Wang, F. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1685591
Physical activity patient education needs in cancer care: a cross-sectional study
Kridis, W. B., Hassen, C. B., Hammouda, I. B., & Khanfir, A. (2025) · BMJ Supportive & Palliative Care · doi:10.1136/spcare-2025-005805
Lun, Q., Gong, M., & Qin, Q. (2025) · Psycho-Oncologie · doi:10.18282/po5611
Metadata
- Authors
- Mustian, K. M., Alfano, C. M., Heckler, C., Kleckner, A. S., Kleckner, I. R., Leach, C. R., Mohr, D., Palesh, O. G., Peppone, L. J., Piper, B. F., Scarpato, J., Smith, T., Sprod, L. K., & Miller, S. M.
- Affiliations
- University of Rochester Medicine (US)
- American Cancer Society (US)
- Northwestern University (US)
- Stanford Cancer Institute (US)
- National University (US)
- Fox Chase Cancer Center (US)
- University of North Carolina Wilmington (US)
- Corresponding author
- Mustian, Karen M.
- ORCID
- Venue
- JAMA Oncology
- Publisher
- American Medical Association (AMA)
- Published
- 2017-07-01
- Volume
- 3
- Issue
- 7
- Pages
- 961
- ISSN
- 2374-2437 (ISSN-L)
- PMC
- PMC5557289
- OpenAlex
- W2593266874
- Cited by
- 932
- References
- 71
- Citations by year
- 2026: 126 · 2025: 97 · 2024: 96 · 2023: 109 · 2022: 129 · 2021: 116 · 2020: 97 · 2019: 78 · 2018: 57 · 2017: 25
- FWCI
- 30.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA Oncology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (UL1TR001422)
- National Cancer Institute (R01CA181659, K07CA168911, R25CA102618, R01CA181064, UG1CA189961, R21CA185678, T32CA102618)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Keywords
- cancer-related fatigue, exercise therapy, psychological intervention, pharmacotherapy, treatment effectiveness comparison, cancer survivors, cancer patients, fatigue severity, quality of evidence, publication bias, treatment effect heterogeneity, exercise duration, exercise frequency
- MeSH terms
- Modafinil, Central Nervous System Stimulants, Benzhydryl Compounds, Dextroamphetamine, Exercise Therapy, Fatigue, Glucocorticoids, Humans, Methylphenidate, Methylprednisolone, Neoplasms, Psychotherapy, Cognitive Behavioral Therapy, Selective Serotonin Reuptake Inhibitors, Paroxetine, Wakefulness-Promoting Agents, Dexmethylphenidate Hydrochloride
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
