Cited by 867Cannabis and Cannabinoid ResearchSchizophrenia research and treatmentPsychedelics and Drug Studies

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Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review

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Volkow, Nora D., Swanson, James M., Evins, A. Eden, DeLisi, Lynn E., Meier, Madeline H., Gonzalez, Raul, Bloomfield, Michael A. P., Curran, H. Valerie, Baler, Ruben·2016·JAMA Psychiatry

DOI 10.1001/jamapsychiatry.2015.3278

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Abstract

With a political debate about the potential risks and benefits of cannabis use as a backdrop, the wave of legalization and liberalization initiatives continues to spread. Four states (Colorado, Washington, Oregon, and Alaska) and the District of Columbia have passed laws that legalized cannabis for recreational use by adults, and 23 others plus the District of Columbia now regulate cannabis use for medical purposes. These policy changes could trigger a broad range of unintended consequences, with profound and lasting implications for the health and social systems in our country. Cannabis use is emerging as one among many interacting factors that can affect brain development and mental function. To inform the political discourse with scientific evidence, the literature was reviewed to identify what is known and not known about the effects of cannabis use on human behavior, including cognition, motivation, and psychosis.

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Authors: Volkow, N. D., Swanson, J. M., Evins, A. E., DeLisi, L. E., Meier, M. H., Gonzalez, R., Bloomfield, M. A. P., Curran, H. V., & Baler, R.
Affiliations: National Institutes of Health (US)
University of California, Irvine (US)
Harvard University (US)
Arizona State University (US)
Center for Children and Families, Department of Psychology, Florida International University, Miami
Hammersmith Hospital (GB)
University College London (GB)
National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland
ORCID: Volkow, Nora D.
Swanson, James M.
Evins, A. Eden
DeLisi, Lynn E.
Meier, Madeline H.
Bloomfield, Michael A. P.
Curran, H. Valerie
Venue: JAMA Psychiatry
Publisher: American Medical Association (AMA)
Published: 2016-03-01
Volume: 73
Issue: 3
Pages: 292
ISSN: 2168-622X (ISSN-L)
DOI: 10.1001/jamapsychiatry.2015.3278
OpenAlex: W2264173627
Cited by: 867
References: 77
Citations by year: 2026: 46 · 2025: 85 · 2024: 64 · 2023: 85 · 2022: 81 · 2021: 87 · 2020: 105 · 2019: 102 · 2018: 97 · 2017: 74 · 2016: 40
FWCI: 84.45
Type: journal article
Language: en
Open access: green
discovery.ucl.ac.uk
Locations: JAMA Psychiatry (publishedVersion)
PubMed (publishedVersion)
UCL Discovery (University College London) (submittedVersion)
Research Bank (Australian Catholic University) (submittedVersion)
Funders: FORUM Pharmaceuticals
National Institute for Health and Care Research (CL-2015-18-005, ACF-2014-18-010)
British Medical Association
National Institutes of Health
Medical Research Council (MR/K015524/1)
National Institute on Drug Abuse (R01DA021576, R01DA021245, R01DA030992)
Topics: Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
Keywords: cannabis use, recreational cannabis legalization, medical cannabis, cognition, motivation, psychosis, brain development, mental health, cannabis policy
MeSH terms: Adult, Behavior, Cannabis, Marijuana Abuse, Cognition, Humans, Legislation, Drug, Motivation, Psychoses, Substance-Induced, United States

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Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review

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