Longitudinal changes in intermuscular fat volume and quadriceps muscle volume in the thighs of women with knee osteoarthritis
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Objective: To quantify rates of change in quadriceps muscle (QM) and intermuscular fat (IMF) volumes over 2 years in women in the Osteoarthritis Initiative (OAI) study and examine group differences between those with radiographic osteoarthritis (ROA) and those without ROA. Methods: The OAI database was queried for women ≥50 years of age in the incident and progression cohorts with and without ROA at baseline. Midthigh magnetic resonance imaging scans (15 contiguous slices, 5 mm slice thickness) of eligible women were randomly selected and anonymized. Image pairs were registered. QM and IMF were segmented in the 12 most proximal matching slices with the segmenter blinded to image time point. Age‐adjusted differences in QM and IMF volume changes between groups were tested using analysis of covariance. Results: Forty‐one women without ROA (mean ± SD age 60.7 ± 7.6 years) and 45 women with ROA (mean ± SD age 64.5 ± 6.7 years) were included. Mean ± SD QM and IMF volume changes in the non‐ROA group were −4.1 ± 11.1 cm 3 and 3.4 ± 7.1 cm 3 , respectively, and −5.4 ± 13.5 cm 3 and 3.1 ± 7.4 cm 3 in the ROA group, respectively. Age‐adjusted between‐group differences in QM and IMF changes were not significant ( P > 0.05). Conclusion: Two‐year changes in QM and IMF volumes appear consistent with aging and do not seem to be related to OA status. Direct comparison with a control cohort without OA risk factors could confirm this. Since group assignment was based on baseline data, there may have been women in the non‐ROA group who developed ROA over followup, resulting in some overlap between groups.
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Changing rates in myosteatosis are likely more related to ageing than any particular disease.
“Furthermore, changing rates in myosteatosis are likely more related to ageing than any particular disease.[ 39 ]”
From Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review (2022) · cites this paper as [39]
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Adipose Tissue as an Endocrine Organ
Kershaw, E. E., & Flier, J. S. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0395 · Cited by 5,522 · see citing works
Longitudinal study of muscle strength, quality, and adipose tissue infiltration
Delmonico, M. J., Harris, T. B., Visser, M., Park, S. W., Conroy, M. B., Velasquez-Mieyer, P., Boudreau, R., Manini, T. M., Nevitt, M., Newman, A. B., et al. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28047 · Cited by 1,446 · see citing works
Aging of skeletal muscle: a 12-yr longitudinal study
Frontera, W. R., Hughes, V. A., Fielding, R. A., Fiatarone, M. A., Evans, W. J., & Roubenoff, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.4.1321 · Cited by 1,443 · see citing works
Visser, M., Goodpaster, B. H., Kritchevsky, S. B., Newman, A. B., Nevitt, M., Rubin, S. M., Simonsick, E. M., Harris, T. B., & Study, F. T. H. A. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.3.324 · Cited by 1,403 · see citing works
Goldring, M. B., & Goldring, S. R. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21258 · Cited by 1,179 · see citing works
Inflammatory markers and loss of muscle mass (sarcopenia) and strength
Schaap, L. A., Pluijm, S. M. F., Deeg, D. J. H., & Visser, M. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2005.10.049 · Cited by 1,047 · see citing works
Quadriceps Weakness and Osteoarthritis of the Knee
Slemenda, C. W., Brandt, K. D., Heilman, D. K., Mazzuca, S. A., Braunstein, E. M., Katz, B. P., & Wolinsky, F. D. (1997) · Annals of Internal Medicine · doi:10.7326/0003-4819-127-2-199707150-00001 · Cited by 964 · see citing works
Anderson, J. J., & Felson, D. T. (1988) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114939 · Cited by 896 · see citing works
Clark, B. C., & Manini, T. M. (2008) · The Journals of Gerontology Series A · doi:10.1093/gerona/63.8.829 · Cited by 876 · see citing works
Visser, M., Kritchevsky, S. B., Goodpaster, B. H., Newman, A. B., Nevitt, M., Stamm, E., & Harris, T. B. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50217.x · Cited by 845 · see citing works
Body Weight, Body Mass Index, and Incident Symptomatic Osteoarthritis of the Hand, Hip, and Knee
Oliveria, S. A., Felson, D. T., Cirillo, P. A., Reed, J. I., & Walker, A. M. (1999) · Epidemiology · doi:10.1097/00001648-199903000-00013 · Cited by 571 · see citing works
Evidence for a key role of leptin in osteoarthritis
Dumond, H., Presle, N., Terlain, B. L., Mainard, D., Lœuille, D., Netter, P., & Pottie, P. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11303 · Cited by 564 · see citing works
Quadriceps weakness in knee osteoarthritis: the effect on pain and disability
O’Reilly, S., Jones, A. C., Muir, K. R., & Doherty, M. (1998) · Annals of the Rheumatic Diseases · doi:10.1136/ard.57.10.588 · Cited by 534 · see citing works
The Role of Mechanical Loading in the Onset and Progression of Osteoarthritis
Griffin, T. M., & Guilak, F. (2005) · Exercise and Sport Sciences Reviews · doi:10.1097/00003677-200510000-00008 · Cited by 479 · see citing works
Skeletal muscle fat infiltration: impact of age, inactivity, and exercise
Marcus, R. L., Addison, O., Kidde, J. P., Dibble, L. E., & Lastayo, P. C. (2010) · The Journal of nutrition, health and aging · doi:10.1007/s12603-010-0081-2 · Cited by 449 · see citing works
THE ROLE OF MUSCLE WEAKNESS IN THE PATHOGENESIS OF OSTEOARTHRITIS
Hurley, M. (1999) · Rheumatic Disease Clinics of North America · doi:10.1016/s0889-857x(05)70068-5 · Cited by 432 · see citing works
Creamer, P., & Hochberg, M. C. (1997) · The Lancet · doi:10.1016/s0140-6736(97)07226-7 · Cited by 394 · see citing works
Obesity and osteoarthritis: more complex than predicted!
Pottie, P., Presle, N., Terlain, B. L., Netter, P., Mainard, D., & Berenbaum, F. (2006) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2006.061994 · Cited by 369 · see citing works
The association of obesity with osteoarthritis of the hand and knee in women: a twin study.
Cicuttini, F., Baker, J., & Spector, T. D. (1996) · PubMed · Cited by 354 · see citing works
Lewek, M. D., Rudolph, K. S., & Snyder‐Mackler, L. (2003) · Journal of Orthopaedic Research® · doi:10.1016/s0736-0266(03)00154-2 · Cited by 347 · see citing works
Sarcopenia and increased adipose tissue infiltration of muscle in elderly African American women
Song, M.-Y., Ruts, E., Kim, J., Janumala, I., Heymsfield, S., & Gallagher, D. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.874 · Cited by 324 · see citing works
The Role of Biomechanics and Inflammation in Cartilage Injury and Repair
Guilak, F., Fermor, B., Keefe, F. J., Kraus, V. B., Olson, S. A., Pisetsky, D. S., Setton, L. A., & Weinberg, J. B. (2004) · Clinical Orthopaedics and Related Research · doi:10.1097/01.blo.0000131233.83640.91 · Cited by 322 · see citing works
Quadriceps Strength and Osteoarthritis Progression in Malaligned and Lax Knees
Sharma, L., Dunlop, D. D., Cahue, S., Song, J., & Hayes, K. W. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-138-8-200304150-00006 · Cited by 319 · see citing works
Stratford, P. W. (2004) · Physiotherapy Canada · doi:10.2310/6640.2004.15377 · Cited by 304 · see citing works
van Beuningen, H. M., Glansbeek, H. L., van der Kraan, P. M., & van den Berg, W. B. (2000) · Osteoarthritis and Cartilage · doi:10.1053/joca.1999.0267 · Cited by 290 · see citing works
Simopoulou, T., Malizos, Κ. Ν., Iliopoulos, D., Stefanou, N., Papatheodorou, L. K., Ιωάννου, Μ., & Tsezou, A. (2007) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2007.01.018 · Cited by 275 · see citing works
Quadriceps weakness predicts risk for knee joint space narrowing in women in the MOST cohort
Segal, N. A., Glass, N. A., Torner, J. C., Yang, M., Felson, D. T., Sharma, L., Nevitt, M. C., & Lewis, C. E. (2010) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2010.02.002 · Cited by 253 · see citing works
Vincenti, M., Coon, C. I., & Brinckerhoff, C. (1998) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199811)41:11 · Cited by 239 · see citing works
Segal, N. A., Torner, J. C., Felson, D. T., Niu, J., Sharma, L., Lewis, C. E., & Nevitt, M. C. (2009) · Arthritis Care & Research · doi:10.1002/art.24541 · Cited by 226 · see citing works
Role of Muscle in the Genesis and Management of Knee Osteoarthritis
Bennell, K. L., Hunt, M. A., Wrigley, T. V., Lim, B., & Hinman, R. S. (2008) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2008.05.005 · Cited by 200 · see citing works
Correlation of synovial fluid leptin concentrations with the severity of osteoarthritis
Ku, J. H., Lee, C., Joo, B. S., An, B. M., Choi, S. H., Wang, T. H., & Cho, H. L. (2009) · Clinical Rheumatology · doi:10.1007/s10067-009-1242-8 · Cited by 176 · see citing works
Age-related quadriceps-dominant muscle atrophy and incident radiographic knee osteoarthritis
Ikeda, S., Tsumura, H., & Torisu, T. (2005) · Journal of Orthopaedic Science · doi:10.1007/s00776-004-0876-2 · Cited by 134 · see citing works
Osteoarthritis and obesity: Experimental models
Gabay, O., Hall, D. J., Berenbaum, F., Henrotin, Y. E., & Sanchez, C. (2008) · Joint Bone Spine · doi:10.1016/j.jbspin.2008.07.011 · Cited by 102 · see citing works
MAGNETIC RESONANCE IMAGING OF PATELLOFEMORAL KINEMATICS WITH WEIGHT-BEARING
Patel, V. V., HALL, K., Ries, M. D., Lindsey, C. T., Ozhinsky, E., Lü, Y., & Majumdar, S. (2003) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-200312000-00021 · Cited by 89 · see citing works
Cotofana, S. C., Hudelmaier, M. I., Wirth, W., Himmer, M., Ring‐Dimitriou, S., Sänger, A. M., & Eckstein, F. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1477-8 · Cited by 61 · see citing works
Quadriceps weakness in osteoarthritis
Hurley, M. (1998) · Current Opinion in Rheumatology · doi:10.1097/00002281-199805000-00015 · Cited by 60 · see citing works
Adipokines in osteoarthritis: friends or foes of cartilage homeostasis?
Pottie, P., Francin, P.-J., Mainard, D., & Presle, N. (2008) · Joint Bone Spine · doi:10.1016/j.jbspin.2008.07.008 · Cited by 48 · see citing works
Segal, N. A., Torner, J. C., Felson, D. T., Niu, J., Sharma, L., Lewis, C. E., & Nevitt, M. C. (2009) · PM&R · doi:10.1016/j.pmrj.2009.03.005 · Cited by 46 · see citing works
Hampton, T. (2004) · JAMA · doi:10.1001/jama.291.16.1951-a · Cited by 36 · see citing works
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Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review
Li, C., Yu, K., Shyh‐Chang, N., Jiang, Z., Liu, T., Ma, S., Luo, L., Guang, L., Liang, K., Ma, W., et al. (2022) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12901 · Cited by 626 · see citing works
Correa-de-Araujo, R., Addison, O., Miljkovic, I., Goodpaster, B. H., Bergman, B. C., Clark, R. V., Elena, J. W., Esser, K. A., Ferrucci, L., Harris-Love, M. O., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00963 · Cited by 468 · see citing works
Recent advances in osteoarthritis imaging—the Osteoarthritis Initiative
Eckstein, F., Wirth, W., & Nevitt, M. C. (2012) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2012.113 · Cited by 254 · see citing works
Quadriceps intramuscular fat fraction rather than muscle size is associated with knee osteoarthritis
Kumar, D., Karampinos, D. C., MacLeod, T. D., Lin, W., Nardo, L., Li, X., Link, T. M., Majumdar, S., & Souza, R. B. (2013) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2013.12.005 · Cited by 160 · see citing works
Quantity and Quality of the Lower Extremity Muscles in Women with Knee Osteoarthritis
Taniguchi, M., Fukumoto, Y., Kobayashi, M., Kawasaki, T., Maegawa, S., Ibuki, S., & Ichihashi, N. (2015) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2015.05.014 · Cited by 102 · see citing works
Eckstein, F., Kwoh, C. K., & Link, T. M. (2014) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2014-205310 · Cited by 100 · see citing works
Myosteatosis increases with aging and is associated with incident diabetes in African ancestry men
Miljkovic, I., Kuipers, A. L., Cvejkus, R., Bunker, C. H., Patrick, A. L., Gordon, C. L., & Zmuda, J. M. (2016) · Obesity · doi:10.1002/oby.21328 · Cited by 89 · see citing works
Role of Thigh Muscle Changes in Knee Osteoarthritis Outcomes: Osteoarthritis Initiative Data.
Mohajer, B., Dolatshahi, M., Moradi, K., Najafzadeh, N., Eng, J., Zikria, B., Wan, M., Cao, X., Roemer, F., Guermazi, A., et al. (2022) · Radiology · doi:10.1148/radiol.212771 · Cited by 91 · see citing works
Maly, M. R., Calder, K. M., MacIntyre, N. J., & BEATTIE, K. A. (2012) · Arthritis Care & Research · doi:10.1002/acr.21868 · Cited by 86 · see citing works
Self-citationSattler, M., Dannhauer, T., Hudelmaier, M. I., Wirth, W., Sänger, A. M., Kwoh, C. K., Hunter, D. J., & Eckstein, F. (2012) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2012.02.635 · Cited by 81 · see citing works
Ceuninck, F. D., Fradin, A., & Pastoureau, P. (2013) · Drug Discovery Today · doi:10.1016/j.drudis.2013.08.004 · Cited by 68 · see citing works
Pedroso, M., de Almeida, A. C., Aily, J., de Noronha, M. D., & Mattiello, S. (2019) · Rheumatology International · doi:10.1007/s00296-019-04271-2 · Cited by 61 · see citing works
Ruhdorfer, A., Wirth, W., Dannhauer, T., & Eckstein, F. (2015) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2015.04.004 · Cited by 50 · see citing works
Dannhauer, T., Ruhdorfer, A., Wirth, W., & Eckstein, F. (2014) · Investigative Radiology · doi:10.1097/rli.0000000000000113 · Cited by 49 · see citing works
Automated unsupervised multi‐parametric classification of adipose tissue depots in skeletal muscle
Valentinitsch, A., Karampinos, D. C., Alizai, H., Subburaj, K., Kumar, D., Link, T. M., & Majumdar, S. (2012) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.23884 · Cited by 48 · see citing works
Davison, M. J., Ioannidis, G., Maly, M. R., Adachi, J. D., & BEATTIE, K. A. (2014) · Clinical Rheumatology · doi:10.1007/s10067-014-2810-0 · Cited by 47 · see citing works
Self-citationde Almeida, A. C., Aily, J., Pedroso, M., Gonçalves, G., Felinto, J. D. C., Ferrari, R., Pastre, C. M., & Mattiello, S. (2019) · Clinical Rheumatology · doi:10.1007/s10067-019-04892-9 · Cited by 37 · see citing works
Kemnitz, J., Wirth, W., Eckstein, F., & Culvenor, A. G. (2018) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2018.05.020 · Cited by 44 · see citing works
Wong, A. K. O., Hummel, K., Moore, C., BEATTIE, K. A., Shaker, S., Craven, B. C., Adachi, J. D., Παπαϊωάννου, Α., & Giangregorio, L. (2014) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2014.04.124 · Cited by 42 · see citing works
Self-citationChen, D., Han, H., Jin, J., Zhou, G., & Li, Z. (2023) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-023-03960-w · Cited by 41 · see citing works
Liao, C., Liao, Y., Liou, T., Hsieh, C.-Y., Kuo, Y., & Chen, H. (2021) · Nutrients · doi:10.3390/nu13082487 · Cited by 41 · see citing works
Dannhauer, T., Sattler, M., Wirth, W., Hunter, D. J., Kwoh, C. K., & Eckstein, F. (2013) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-013-0418-z · Cited by 39 · see citing works
Ruhdorfer, A., Dannhauer, T., Wirth, W., Hitzl, W., Kwoh, C. K., Guermazi, A., Hunter, D. J., Bénichou, O., Eckstein, F., & For The Osteoarthritis Initiative Investigators (2013) · Arthritis Care & Research · doi:10.1002/acr.21965 · Cited by 37 · see citing works
Wong, A. K. O., BEATTIE, K. A., Min, K. K. H., Gordon, C. L., Pickard, L. E., Παπαϊωάννου, Α., & Adachi, J. D. (2014) · PubMed · Cited by 37 · see citing works
Self-citationRelationships between fatty infiltration in the thigh and calf in women with knee osteoarthritis
Davison, M. J., Maly, M. R., Adachi, J. D., Noseworthy, M. D., & BEATTIE, K. A. (2016) · Aging Clinical and Experimental Research · doi:10.1007/s40520-016-0556-z · Cited by 28 · see citing works
Self-citationRuhdorfer, A., Wirth, W., & Eckstein, F. (2015) · Arthritis & Rheumatology · doi:10.1002/art.39484 · Cited by 27 · see citing works
Ruhdorfer, A., Dannhauer, T., Wirth, W., Cotofana, S. C., Roemer, F. W., Nevitt, M. C., & Eckstein, F. (2014) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2014.06.002 · Cited by 27 · see citing works
Khanna, R., Saltzman, M. D., Elliott, J. M., Hoggarth, M. A., Marra, G. M., Omar, I. M., Parrish, T. B., & Seitz, A. L. (2019) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-019-2631-z · Cited by 24 · see citing works
Nakatani, M., Takai, Y., Akagi, R., Wakahara, T., Sugisaki, N., Ohta, M., Kawakami, Y., Fukunaga, T., & Kanehisa, H. (2016) · European Journal of Applied Physiology · doi:10.1007/s00421-016-3464-1 · Cited by 26 · see citing works
Association between sarcopenia and osteoarthritis: A protocol for meta-analysis
Wang, H., Wang, N., Wang, Y., & Li, H. (2022) · PLoS ONE · doi:10.1371/journal.pone.0272284 · Cited by 23 · see citing works
Teoli, A., Martel‐Pelletier, J., Abram, F., Pelletier, J., & Robbins, S. M. K. (2022) · Clinical Biomechanics · doi:10.1016/j.clinbiomech.2022.105669 · Cited by 21 · see citing works
Yagi, M., Taniguchi, M., Tateuchi, H., Hirono, T., Yamagata, M., Umehara, J., Nojiri, S., Kobayashi, M., & Ichihashi, N. (2021) · Clinical Biomechanics · doi:10.1016/j.clinbiomech.2021.105546 · Cited by 20 · see citing works
Karapınar, M., AYYILDIZ, V. A., Ünal, M., & Fırat, T. (2022) · Journal of Orthopaedic Science · doi:10.1016/j.jos.2022.11.011 · Cited by 20 · see citing works
Ponrartana, S., Andrade, K. E., Wren, T. A. L., Ramos-Platt, L. M., Hu, P., Blüml, S., & Gilsanz, V. (2014) · American Journal of Roentgenology · doi:10.2214/ajr.13.11081 · Cited by 18 · see citing works
Yamauchi, K., Kato, C., & Kato, T. (2019) · Rheumatology International · doi:10.1007/s00296-019-04247-2 · Cited by 17 · see citing works
Sattler, M., Dannhauer, T., Ring‐Dimitriou, S., Sänger, A. M., Wirth, W., Hudelmaier, M. I., & Eckstein, F. (2014) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2014.07.005 · Cited by 15 · see citing works
Culvenor, A. G., Boeth, H., Diederichs, G., Wirth, W., Duda, G. N., & Eckstein, F. (2016) · PubMed Central · doi:10.26181/22106396 · Cited by 15 · see citing works
Karampatos, S., Παπαϊωάννου, Α., BEATTIE, K. A., Maly, M. R., Chan, A., Adachi, J. D., & Pritchard, J. M. (2015) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-015-0510-7 · Cited by 15 · see citing works
Self-citationYamauchi, K., Yoshiko, A., Suzuki, S., Kato, C., Akima, H., Kato, T., & Ishida, K. (2017) · Journal of orthopaedic surgery · doi:10.1177/2309499017739765 · Cited by 14 · see citing works
Mohajer, B., Moradi, K., Guermazi, A., Dolatshahi, M., Zikria, B. A., Najafzadeh, N., Kalyani, R. R., Roemer, F. W., Berenbaum, F., & Demehri, S. (2022) · European Radiology · doi:10.1007/s00330-022-09035-4 · Cited by 14 · see citing works
Pritchard, J. M., Karampatos, S., BEATTIE, K. A., Giangregorio, L., Ioannidis, G., Atkinson, S. A., Thabane, L., Gerstein, H. C., Punthakee, Z., Adachi, J. D., et al. (2015) · Journal of Aging Research · doi:10.1155/2015/872726 · Cited by 12 · see citing works
Self-citationTan, C., Yan, Z., Yang, D., Li, K., Yu, H. J., Engelke, K., Miller, C. G., & Metaxas, D. (2015) · IEEE International Symposium on Biomedical Imaging (ISBI) · doi:10.1109/isbi.2015.7164071 · Cited by 11 · see citing works
Unique Barriers and Needs in Weight Management for Obese Women with Fibromyalgia
Craft, J. M., Ridgeway, J. L., Vickers, K. S., Hathaway, J. C., Vincent, A., & Oh, T. H. (2014) · EXPLORE · doi:10.1016/j.explore.2014.10.005 · Cited by 10 · see citing works
An Automated and Robust Framework for Quantification of Muscle and Fat in the Thigh
Tan, C., Yan, Z., Zhang, S., Belaroussi, B., Yu, H. J., Miller, C. G., & Metaxas, D. (2014) · Proceedings - International Conference on Pattern Recognition/Proceedings/International Conference on Pattern Recognition · doi:10.1109/icpr.2014.547 · Cited by 10 · see citing works
Arterio-venous balance studies of skeletal muscle fatty acid metabolism: what can we believe?
Guo, Z., & Jensen, M. D. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00346.2013 · Cited by 10 · see citing works
Kemnitz, J., Steidle‐Kloc, E., Wirth, W., Fürst, D., Wisser, A., Eder, S. K., & Eckstein, F. (2021) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2021.151866 · Cited by 7 · see citing works
Aily, J. B., Noronha, M. A. D., Ferrari, R. J., & Mattiello, S. M. (2025) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-025-08347-y · Cited by 5 · see citing works
Ivanochko, N. K., Gatti, A. A., Stratford, P. W., & Maly, M. R. (2024) · Clinical Rheumatology · doi:10.1007/s10067-024-07014-2 · Cited by 4 · see citing works
Self-citationManatrakul, R., Pirmoazen, A. M., Bharadwaj, U. U., Akkaya, Z., Giesler, P. J., Lynch, J. A., Nevitt, M. C., McCulloch, C. E., Joseph, G. B., & Link, T. M. (2024) · Skeletal Radiology · doi:10.1007/s00256-024-04565-y · Cited by 3 · see citing works
Steidle‐Kloc, E., Dannhauer, T., Wirth, W., & Eckstein, F. (2021) · Cells Tissues Organs · doi:10.1159/000520037 · Cited by 3 · see citing works
Perera, M. R., Bydder, G. M., Holdsworth, S. J., & Handsfield, G. G. (2025) · Journal of Imaging · doi:10.3390/jimaging11020043 · Cited by 2 · see citing works
Leonardis, J. M. (2013) · Cited by 1 · see citing works
Fitze, D. P., Mair‐Noack, N., Brun, D., Nanz, D., Snedeker, J. G., & Spörri, J. (2025) · Physiological Reports · doi:10.14814/phy2.70263 · Cited by 1 · see citing works
(2012) · Current Opinion in Rheumatology · doi:10.1097/bor.0b013e32835c12b6 · Cited by 1 · see citing works
Lorbergs, A. L., Noseworthy, M. D., & MacIntyre, N. J. (2016) · Journal of medical imaging and radiation sciences · doi:10.1016/j.jmir.2016.09.004
Self-citationHoki, A., D’Amico, E., Ambrosio, F., Matsuda, Y., & Iijima, H. (2023) · medRxiv · doi:10.1101/2023.04.16.23288640
Wang, Z., Yan, H., Yu, Y., Lian, M., hao, G., & Luo, W. (2023) · Research Square · doi:10.21203/rs.3.rs-3389378/v1
Chen, S., Han, H., Jin, J., Zhou, G., & Li, Z. (2024) · Figshare · doi:10.6084/m9.figshare.26604394
Tam, K., Liu, S. W., Ianes, S. C., Szabo, E., Reitsma, S., Gillick, H., Adachi, J. D., & Wong, A. K. O. (2026) · Calcified Tissue International · doi:10.1007/s00223-026-01529-3
Xin¹, D., Huan¹, M., Guo, X., Rui¹, L., Fei¹, F., Zhao, H., Guo, L., Yeda, W., & Zhen¹, H. (2026) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-026-10167-7
梁志, Yang, G., Zhang, J., Tan, B., Dong, Y., & Yan, Y. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1886678
Intramuscular Fat Infiltration and Knee Osteoarthritis: A Systematic Review and Meta‐Analysis
Yu, L., Chen, C., Zhang, G., Huang, Q., Miao, Y., Makihara, Y., & Nishida, Y. (2026) · Physiotherapy Research International · doi:10.1002/pri.70330
Myosteatosis: an emerging biomarker of aging
Roe, L. S., Zmuda, J. M., & Miljkovic, I. (2026) · Frontiers in Aging · doi:10.3389/fragi.2026.1868010
Davison, M. J. (2014) · MacSphere (McMaster University) · doi:10.71548/12968
- Authors
- Beattie, K. A., MacIntyre, N. J., Ramadan, K., Inglis, D., & Maly, M. R.
- Affiliations
- McMaster University (CA)
- Corresponding author
- Beattie, Karen A.
- Venue
- Arthritis Care & Research
- Publisher
- Wiley
- Published
- 2011-12-28
- Volume
- 64
- Issue
- 1
- Pages
- 22-29
- ISSN
- 0893-7524 (ISSN-L)
- 2151-464X
- 2151-4658
- PMC
- PMC3251718
- OpenAlex
- W2072412536
- Cited by
- 65
- References
- 39
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 3 · 2023: 3 · 2022: 6 · 2021: 4 · 2020: 1 · 2019: 5 · 2018: 1 · 2017: 1 · 2016: 4 · 2015: 7 · 2014: 11 · 2013: 6 · 2012: 5
- FWCI
- 4.80
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Arthritis Care & Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (n01ar22260-13-0-1, n01ar22258-16-0-1, n01ar22259-12-0-1, n01ar22262-12-0-1, n01ar22261-13-0-1)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (N01 ‐ AR ‐ 2 ‐ 2261, N01‐AR‐2‐2260, N01 AR022262, N01 AR022260, N01 ‐ AR ‐ 2 ‐ 2258, N01 AR022261, N01-AR-2- 2262, N01 AR022259, N01 AR022258, N01AR22259)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Rheumatology › Osteoarthritis Treatment and Mechanisms
- Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
- Keywords
- knee osteoarthritis, intermuscular fat, thigh muscle volume, longitudinal change, women, aging, radiographic osteoarthritis, Osteoarthritis Initiative, magnetic resonance imaging, muscle atrophy
- MeSH terms
- Age Factors, Aged, Aging, Analysis of Variance, Canada, Female, Humans, Longitudinal Studies, Magnetic Resonance Imaging, Middle Aged, Organ Size, Radiography, Sex Factors, Time Factors, Case-Control Studies, Disease Progression, Osteoarthritis, Knee, Adiposity, Quadriceps Muscle
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