The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Biomimetic Scaffolds for Tissue Engineering
Open accessAbstract
Biomimetic scaffolds mimic important features of the extracellular matrix (ECM) architecture and can be finely controlled at the nano‐ or microscale for tissue engineering. Rational design of biomimetic scaffolds is based on consideration of the ECM as a natural scaffold; the ECM provides cells with a variety of physical, chemical, and biological cues that affect cell growth and function. There are a number of approaches available to create 3D biomimetic scaffolds with control over their physical and mechanical properties, cell adhesion, and the temporal and spatial release of growth factors. Here, an overview of some biological features of the natural ECM is presented and a variety of original engineering methods that are currently used to produce synthetic polymer‐based scaffolds in pre‐fabricated form before implantation, to modify their surfaces with biochemical ligands, to incorporate growth factors, and to control their nano‐ and microscale geometry to create biomimetic scaffolds are discussed. Finally, in contrast to pre‐fabricated scaffolds composed of synthetic polymers, injectable biomimetic scaffolds based on either genetically engineered‐ or chemically synthesized‐peptides of which sequences are derived from the natural ECM are discussed. The presence of defined peptide sequences can trigger in situ hydrogelation via molecular self‐assembly and chemical crosslinking. A basic understanding of the entire spectrum of biomimetic scaffolds provides insight into how they can potentially be used in diverse tissue engineering, regenerative medicine, and drug delivery applications.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Matrix elasticity directs stem cell lineage specification
Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915
Mussel-inspired surface chemistry for multifunctional coatings
Lee, H., Dellatore, S. M., Miller, W. M., & Messersmith, P. B. (2007) · Science · doi:10.1126/science.1147241 · Cited by 10,965
Hynes (2002) · doi:10.1016/s0092-8674(02)00971-6 · Cited by 8,606
Mediation of biomaterial-cell interactions by adsorbed proteins: a review
Wilson, C. J., Clegg, R. E., Leavesley, D. I., & Pearcy, M. J. (2005) · Tissue Engineering · doi:10.1089/ten.2005.11.1 · Cited by 1,696
The effect of scaffold degradation rate on three-dimensional cell growth and angiogenesis
Sung, H.-J., Meredith, C., Johnson, C., & Galis, Z. S. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2004.01.066 · Cited by 804
Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation
Keselowsky, B. G., Collard, D. M., & García, A. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407356102 · Cited by 687
Fedorovich, N. E., Alblas, J., de Wijn, J. R., Hennink, W. E., Verbout, A. J., & Dhert, W. J. A. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0175 · Cited by 467
Electrospun nanostructured scaffolds for bone tissue engineering
Prabhakaran, M. P., Venugopal, J., & Ramakrishna, S. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.05.007 · Cited by 430
Lyons, F. G., Al-Munajjed, A. A., Kieran, S. M., Toner, M. E., Murphy, C. M., Duffy, G. P., & O’Brien, F. J. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.08.056 · Cited by 222
Substrate topography shapes cell function
Kulangara, K., & Leong, K. W. (2009) · Soft Matter · doi:10.1039/b910132m · Cited by 145
Cited by
Hinderer, S., Layland, S. L., & Schenke-Layland, K. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.11.019 · Cited by 469
Amani, H., Arzaghi, H., Bayandori, M., Dezfuli, A. S., Pazoki‐Toroudi, H., Shafiee, A., & Moradi, L. (2019) · Advanced Materials Interfaces · doi:10.1002/admi.201900572 · Cited by 436
Hinderer, S., Brauchle, E., & Schenke‐Layland, K. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201400762 · Cited by 68
Zheng, T., Guo, L., Du, Z., Leng, H., Cai, Q., & Yang, X. (2021) · Ceramics International · doi:10.1016/j.ceramint.2021.03.234 · Cited by 39
Luo, P., Huang, R., Wu, Y., Liu, X., Shan, Z., Gong, L., Deng, S., Liu, H., Fang, J., Wu, S., et al. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.05.011 · Cited by 36
Colangelo, M. T., Belletti, S., Govoni, P., Guizzardi, S., & Galli, C. (2021) · Applied Sciences · doi:10.3390/app11104405 · Cited by 28
Metadata
- Authors
- Kim, T. G., Shin, H., & Lim, D. W.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2012-03-21
- Volume
- 22
- Issue
- 12
- Pages
- 2446-2468
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2026916005
- Cited by
- 459
- References
- 11
- FWCI
- 12.73
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
