The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Metal‐Organic Framework Nanoparticles in Photodynamic Therapy: Current Status and Perspectives
Abstract
This feature article covers the recent applications of metal‐organic framework nanoparticles (MOF NPs) in photodynamic therapy (PDT) of cancer. It aims at giving the reader an overview about these two current research fields, i.e., MOF and PDT, and at highlighting the potential synergistic effect that could result from their association. After describing the general photophysics and photochemistry that underlie PDT, the relationship between photosensitizer (PS) properties and PDT requirements is discussed throughout the PSs historical development. This development reveals the advantages of using nanotechnology platforms for the creation of the ideal PS and leads us to define the fourth generation of PSs, which includes NPs built from the PS itself as porphysomes or PS‐based MOF NPs. Especially, the precise spatial control over the PS assembly into well‐defined MOF NPs, which keeps the PS in its monomeric form and prevents PS self‐quenching, appears as a notable feature to solve PS solubility and aggregation issues and therefore improves the PDT efficiency. Finally, we discuss the future perspectives of MOF NPs in PDT and shed light on how promising these nanomaterials are.
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Cites
Nanocarriers as an emerging platform for cancer therapy
Peer, D., Karp, J. M., Hong, S., Farokhzad, O. C., Margalit, R., & Langer, R. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.387 · Cited by 8,710
Metal-organic framework materials as catalysts
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Photodynamic therapy of cancer: An update
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Drug Delivery Systems: Entering the Mainstream
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Oxygen Consumption and Diffusion Effects in Photodynamic Therapy
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Cited by
Supramolecular cancer nanotheranostics
Zhou, J., Rao, L., Yu, G., Cook, T. R., Chen, X., & Huang, F. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00011f · Cited by 411
Min, H., Wang, J., Qi, Y., Zhang, Y., Han, X., Xu, Y., Xu, J., Li, Y., Chen, L., Cheng, K., et al. (2019) · Advanced Materials · doi:10.1002/adma.201808200 · Cited by 394
Jiang, X., Zhang, L., Liu, S., Zhang, Y., He, Z., Li, W., Zhang, F., Shi, Y., Lü, W., Li, Y., et al. (2018) · Advanced Optical Materials · doi:10.1002/adom.201800561 · Cited by 336
Dong, Z., Sun, Y., Chu, J., Zhang, X., & Deng, H. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b07392 · Cited by 282
Endogenous Hydrogen Sulfide-Triggered MOF-Based Nanoenzyme for Synergic Cancer Therapy
Li, Y., Zhou, J., Wang, L., & Xie, Z. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c08659 · Cited by 125
Metadata
- Authors
- Lismont, M., Dreesen, L., & Wuttke, S.
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2017-03-03
- Volume
- 27
- Issue
- 14
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2594479214
- Cited by
- 622
- References
- 6
- FWCI
- 56.50
- Type
- journal article
- Language
- en
- Open access
- closed
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