Precise Diffusion of Gaseous H 2 S “Bomb” Potentiates NIR‐II Imaging‐Guided Photothermal Therapy by Relieving Heat Tolerance and Disturbing Cellular Homeostasis for Synergistic Orthotopic Glioblastoma Treatment
Open accessAbstract
Although photothermal therapy (PTT) has thrived as a novel cancer treatment method with the merits of high spatiotemporal specificity and minimal invasion, the limited penetration depth and poor blood−brain barrier permeability pose significant challenges in glioblastoma (GBM) treatment. Here, a near‐infrared‐II (NIR‐II) emissive nanosystem based on aggregation‐induced emission photothermal agents and H 2 S prodrug for brain‐targeted orthotopic GBM synergistic therapy is innovatively developed. It achieves through‐skull tumor visualization by NIR‐II/photothermal imaging, assisting in real‐time monitoring of GBM in the brain area. Moreover, the in situ released H 2 S triggered by photothermal stimulation efficiently infiltrates deep tumors and evokes mitochondrial dysfunction and cellular apoptosis. The gas therapy can also deplete ATP and subsequently downregulate HSP90 expression, thus inhibiting the heat tolerance of lethal tumors and enhancing PTT for GBM. Incorporating non invasive H 2 S gas “bomb” in GBM therapy may drive the clinical application of PTT, reducing the risk of incomplete tumor cell eradication due to intrinsic resistance to thermal.
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The photothermal effect of ApoE@TAhL promoted deformation of the temperature-sensitive liposomal membrane, triggering H2S release, which induced intracellular oxidative stress and downregulation of ATP levels.
“The photothermal effect further promoted the deformation of the temperature-sensitive liposomal membrane, triggering the release of H2S, which induced intracellular oxidative stress and downregulation of ATP levels.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [234]
In vivo, ApoE@TAhL effectively penetrated the BBB and accumulated at the GBM site, exhibiting superior NIR-II real-time imaging performance and photothermal effect under 808 nm laser irradiation.
“In vivo experiments showed that ApoE@TAhL effectively penetrated the BBB and accumulated at the GBM site, exhibiting superior NIR-II real-time imaging performance and photothermal effect under 808 nm laser irradiation.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [234]
Reduced ATP levels led to decreased HSP90 expression, thereby suppressing tumor thermotolerance and enhancing PTT efficacy.
“Reduced ATP levels led to decreased HSP90 expression, thereby suppressing tumor thermotolerance and enhancing PTT efficacy.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [234]
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Cites
Double-slit photoelectron interference in strong-field ionization of the neon dimer
Kunitski, M., Eicke, N., Huber, P., Köhler, J., Zeller, S., Voigtsberger, J., Schlott, N., Henrichs, K., Sann, H., Trinter, F., et al. (2019) · Institutional Repository of Leibniz Universität Hannover (Leibniz Universität Hannover) · doi:10.15488/5174 · Cited by 8,378 · see citing works
Double-slit photoelectron interference in strong-field ionization of the neon dimer
Kunitski, M., Eicke, N., Huber, P., Köhler, J., Zeller, S., Voigtsberger, J., Schlott, N., Henrichs, K., Sann, H., Trinter, F., et al. (2019) · Nature Communications · doi:10.1038/s41467-018-07882-8 · Cited by 8,162 · see citing works
Targeting the dynamic HSP90 complex in cancer
Trepel, J. B., Mollapour, M., Giaccone, G., & Neckers, L. (2010) · Nature reviews. Cancer · doi:10.1038/nrc2887 · Cited by 1,523 · see citing works
Key principles and methods for studying the endocytosis of biological and nanoparticle therapeutics
Rennick, J. J., Johnston, A. P. R., & Parton, R. G. (2021) · Nature Nanotechnology · doi:10.1038/s41565-021-00858-8 · Cited by 1,500 · see citing works
Strategies for delivering therapeutics across the blood–brain barrier
Terstappen, G. C., Meyer, A. H., Bell, R. D., & Zhang, W. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00139-y · Cited by 1,138 · see citing works
Synthesis of Copper Peroxide Nanodots for H 2 O 2 Self-Supplying Chemodynamic Therapy
Lin, L., Huang, T., Song, J., Ou, X., Wang, Z., Deng, H., Tian, R., Liu, Y., Wang, J., Liu, Y., et al. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.9b03457 · Cited by 1,133 · see citing works
Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics
Tang, W., Fan, W., Lau, J., Deng, L., Shen, Z., & Chen, X. S. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00805a · Cited by 606 · see citing works
Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells
Chen, J., McKay, R. M., & Parada, L. F. (2012) · Cell · doi:10.1016/j.cell.2012.03.009 · Cited by 526 · see citing works
NIR‐II AIEgens: A Win–Win Integration towards Bioapplications
Xu, W., Wang, D., & Tang, B. Z. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202005899 · Cited by 460 · see citing works
Self-citationActivatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer
Jiang, Y., Huang, J., Xu, C., & Pu, K. (2021) · Nature Communications · doi:10.1038/s41467-021-21047-0 · Cited by 443 · see citing works
Guo, B., Sheng, Z., Hu, D., Liu, C., Zheng, H., & Liu, B. (2018) · Advanced Materials · doi:10.1002/adma.201802591 · Cited by 437 · see citing works
Zhou, J., Li, M., Hou, Y., Luo, Z., Chen, Q., Cao, H., Huo, R., Xue, C., Sutrisno, L., Hao, L., et al. (2018) · ACS Nano · doi:10.1021/acsnano.8b00309 · Cited by 424 · see citing works
Local generation of hydrogen for enhanced photothermal therapy
Zhao, P., Jin, Z., Chen, Q., Yang, T., Chen, D., Jin, M., Lu, X., Gu, Z., & He, Q. (2018) · Nature Communications · doi:10.1038/s41467-018-06630-2 · Cited by 381 · see citing works
Self-citationAdvances in local therapy for glioblastoma — taking the fight to the tumour
van Solinge, T. S., Nieland, L., Chiocca, E. A., & Broekman, M. L. D. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-022-00621-0 · Cited by 335 · see citing works
Jiang, L., Bai, H., Liu, L., Lv, F., Ren, X., & Wang, S. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201905884 · Cited by 289 · see citing works
Deng, G., Peng, X., Sun, Z., Zheng, W., Yu, J., Du, L., Chen, H., Gong, P., Zhang, P., Cai, L., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c03824 · Cited by 252 · see citing works
Self-citationZou, Y., Sun, X., Yang, Q., Zheng, M., Shimoni, O., Ruan, W., Wang, Y., Zhang, D., Yin, J., Huang, X., et al. (2022) · Science Advances · doi:10.1126/sciadv.abm8011 · Cited by 227 · see citing works
A Bacteria‐Responsive Porphyrin for Adaptable Photodynamic/Photothermal Therapy
Hu, H., Wang, H., Yang, Y., Xu, J., & Zhang, X. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202200799 · Cited by 211 · see citing works
Jiang, Y., Zhang, J., Meng, F., & Zhong, Z. (2018) · ACS Nano · doi:10.1021/acsnano.8b05265 · Cited by 201 · see citing works
FeS@BSA Nanoclusters to Enable H 2 S‐Amplified ROS‐Based Therapy with MRI Guidance
Xie, C., Cen, D., Ren, Z., Wang, Y., Wu, Y., Li, X., Han, G., & Cai, X. (2020) · Advanced Science · doi:10.1002/advs.201903512 · Cited by 178 · see citing works
Xiao, P., Xie, W., Zhang, J., Wu, Q., Shen, Z., Guo, C., Wu, Y., Wang, F., Tang, B. Z., & Wang, D. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c10076 · Cited by 177 · see citing works
Self-citationA “Closed‐Loop” Therapeutic Strategy Based on Mutually Reinforced Ferroptosis and Immunotherapy
Du, Y., Zhang, R., Yang, J., Liu, S., Zhou, J., Zhao, R., He, F., Zhang, Y., Yang, P., & Lin, J. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202111784 · Cited by 169 · see citing works
Gold‐Nanosponge‐Based Multistimuli‐Responsive Drug Vehicles for Targeted Chemo‐Photothermal Therapy
Zheng, T., Li, G. G., Zhou, F., WU, R. T., Zhu, J., & Wang, H. (2016) · Advanced Materials · doi:10.1002/adma.201602486 · Cited by 165 · see citing works
Wang, J., Liu, Y., Morsch, M., Lu, Y., Shangguan, P., Han, L., Wang, Z., Chen, X., Song, C., Liu, S., et al. (2022) · Advanced Materials · doi:10.1002/adma.202106082 · Cited by 163 · see citing works
Self-citationWang, Y., Li, Y., Zhang, Z., Wang, L., Wang, D., & Tang, B. Z. (2021) · Advanced Materials · doi:10.1002/adma.202103748 · Cited by 153 · see citing works
Self-citationKuo, P., Chen, C., & Hsu, Y. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-1089 · Cited by 152 · see citing works
Du, Y., Zhao, X., He, F., Gong, H., Yang, J., Wu, L., Cui, X., Gai, S., Yang, P., & Lin, J. (2024) · Advanced Materials · doi:10.1002/adma.202403253 · Cited by 130 · see citing works
Zhang, D., Tian, S., Liu, Y., Zheng, M., Yang, X., Zou, Y., Shi, B., & Luo, L. (2022) · Nature Communications · doi:10.1038/s41467-022-34462-8 · Cited by 121 · see citing works
Liu, Y., Wang, W., Zhang, D., Sun, Y., Li, F., Zheng, M., Lovejoy, D. B., Zou, Y., & Shi, B. (2022) · Exploration · doi:10.1002/exp.20210274 · Cited by 120 · see citing works
Gas‐Mediated Tumor Energy Remodeling for Sensitizing Mild Photothermal Therapy
Cheng, J., Zhu, Y., Dai, Y., Li, L., Zhang, M., Jin, D., Liu, M., Yu, J., Yu, W., Su, D., et al. (2023) · Angewandte Chemie International Edition · doi:10.1002/anie.202304312 · Cited by 114 · see citing works
Li, Y., Tang, R., Liu, X., Gong, J., Zhao, Z., Sheng, Z., Zhang, J., Li, X., Niu, G., Kwok, R. T. K., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c05610 · Cited by 104 · see citing works
Self-citationBreaking barriers for glioblastoma with a path to enhanced drug delivery
Noorani, I., & Rosa, J. D. L. (2023) · Nature Communications · doi:10.1038/s41467-023-41694-9 · Cited by 102 · see citing works
Yang, L., Zhao, Z., Tian, B., Yang, M., Dong, Y., Zhou, B., Gai, S., Xie, Y. H., & Lin, J. (2024) · Nature Communications · doi:10.1038/s41467-024-51772-1 · Cited by 101 · see citing works
He, X., Luo, Y., Li, Y., Pan, Y., Kwok, R. T. K., He, L., Duan, X., Zhang, P., Wu, A., Tang, B. Z., et al. (2023) · Aggregate · doi:10.1002/agt2.396 · Cited by 87 · see citing works
Self-citationSimulating the exchange of Majorana zero modes with a photonic system
Xu, J., Sun, K., Han, Y., Li, C.-F., Pachos, J. K., & Guo, G.-C. (2016) · Nature Communications · doi:10.1038/ncomms13194 · Cited by 70 · see citing works
Chen, L., Chen, S., Yuan, Y., Leng, X., Xu, X., Chen, J., Shi, J., Qian, K., Xie, Y., Ding, Q., et al. (2024) · Aggregate · doi:10.1002/agt2.657 · Cited by 68 · see citing works
Jiang, S., Li, W., Yang, J. J., Zhang, T., Zhang, Y., Xu, L., Hu, B., Li, Z., Gao, H., Huang, Y., et al. (2024) · ACS Nano · doi:10.1021/acsnano.3c11958 · Cited by 62 · see citing works
Self-citationAnalysis and modeling of cancer drug responses using cell cycle phase-specific rate effects
Gross, S. M., Mohammadi, F., Sanchez-Aguila, C., Zhan, P. J., Liby, T. A., Dane, M. A., Meyer, A. S., & Heiser, L. M. (2023) · Nature Communications · doi:10.1038/s41467-023-39122-z · Cited by 55 · see citing works
Qi, M., Wang, D., Wang, Q., Zhang, Z., Ao, Y., Li, J., & Huang, S. (2024) · Advanced Materials · doi:10.1002/adma.202412191 · Cited by 55 · see citing works
You, P., Suo, M., Huang, Q., Lyu, M., Jiang, Y. H., Wang, S., Tang, W., Ning, S., & Zhang, T. (2023) · Aggregate · doi:10.1002/agt2.432 · Cited by 53 · see citing works
Self-citationZhang, J., Han, L., Wu, H., Zhong, Y., Shangguan, P., Liu, Y., He, M., Sun, H., Song, C., Wang, X., et al. (2023) · Advanced Science · doi:10.1002/advs.202206333 · Cited by 47 · see citing works
Self-citationCai, F., Xu, H., Cao, N., Zhang, X., Liu, J., Lu, Y., Chen, J., Yang, Y., Cheng, J. G., Hua, Z.-C., et al. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-2222-9 · Cited by 46 · see citing works
Li, S., Chen, Z., Guo, W., Tan, L., Wu, Q., Ren, X., Fu, C., Wang, Q., Huang, Z., & Meng, X. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202314742 · Cited by 35 · see citing works
Lin, X., Sun, Z., Huang, S., Liu, C., Peng, J., Li, Y., Xiong, Y., Gao, H., Chen, J., Qi, J., et al. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202310237 · Cited by 28 · see citing works
Walker, F. M., Sobral, L. M., Danis, E. P., Sanford, B. L., Donthula, S., Balakrishnan, I., Wang, D., Pierce, A. M., Karam, S. D., Kargar, S., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-48214-3 · Cited by 11 · see citing works
Flagged first, then by citations
Research works printed but not linked: 43
- J. Chen, R. M. McKay, L. F. Parada, Cell 2012, 149, 36.
- T. S. van Solinge, L. Nieland, E. A. Chiocca, M. L. D. Broekman, Nat. Rev. Neurol. 2022, 18, 221.
- X. He, Y. Luo, Y. Li, Y. Pan, R. T. K. Kwok, L. He, X. Duan, P. Zhang, A. Wu, B. Z. Tang, J. Li, Aggregate 2024, 5, e396.
- Y. Du, R. Zhang, J. Yang, S. Liu, J. Zhou, R. Zhao, F. He, Y. Zhang, P. Yang, J. Lin, Adv. Funct. Mater. 2022, 32, 2111784.
- L. Yang, Z. Zhao, B. Tian, M. Yang, Y. Dong, B. Zhou, S. Gai, Y. Xie, J. Lin, Nat. Commun. 2024, 15, 7499.
- I. Noorani, J. de la Rosa, Nat. Commun. 2023, 14, 5909.
- G. C. Terstappen, A. H. Meyer, R. D. Bell, W. Zhang, Nat. Rev. Drug. Discov. 2021, 20, 362.
- W. Tang, W. Fan, J. Lau, L. Deng, Z. Shen, X. Chen, Chem. Soc. Rev. 2019, 48, 2967.
- S. Jiang, W. Li, J. Yang, T. Zhang, Y. Zhang, L. Xu, B. Hu, Z. Li, H. Gao, Y. Huang, S. Ruan, ACS Nano 2024, 18, 6445.
- Y. Zou, X. Sun, Q. Yang, M. Zheng, O. Shimoni, W. Ruan, Y. Wang, D. Zhang, J. Yin, X. Huang, W. Tao, J. B. Park, X.-J. Liang, K. W. Leong, B. Shi, Sci. Adv. 2025, 8, 8011.
- Q. Chen, L. Xu, C. Liang, C. Wang, R. Peng, Z. Liu, Nat. Commun. 2016, 7, 13194.
- Y. Jiang, J. Huang, C. Xu, K. Pu, Nat. Commun. 2021, 12, 742.
- L. Jiang, H. Bai, L. Liu, F. Lv, X. Ren, S. Wang, Angew. Chem. Inter. Ed. 2019, 58, 10660.
- Y. Pan, M. Suo, Q. Huang, M. Lyu, Y. Jiang, S. Wang, W. Tang, S. Ning, T. Zhang, Aggregate 2023, 5, 432.
- L. Chen, S.-L. Chen, Y. Yuan, X. Leng, X. Xu, J. Chen, J. Shi, K. Qian, Y. Xie, Q. Ding, Z. Cheng, M. Gu, Aggregate 2024, 5, 657.
- M.-H. Qi, D.-D. Wang, W. Qian, Z.-L. Zhang, Y.-W. Ao, J.-M. Li, S.-W. Huang, Adv. Mater. 2025, 37, 2412191.
- Y. Du, X. Zhao, F. He, H. Gong, J. Yang, L. Wu, X. Cui, S. Gai, P. Yang, J. Lin, Adv. Mater. 2024, 36, 2403253.
- T. Zheng, G. G. Li, F. Zhou, R. Wu, J.-J. Zhu, H. Wang, Adv. Mater. 2016, 28, 8218.
- G. Deng, X. Peng, Z. Sun, W. Zheng, J. Yu, L. Du, H. Chen, P. Gong, P. Zhang, L. Cai, B. Z. Tang, ACS Nano 2020, 14, 11452.
- P. Xiao, W. Xie, J. Zhang, Q. Wu, Z. Shen, C. Guo, Y. Wu, F. Wang, B. Z. Tang, D. Wang, J. Am. Chem. Soc. 2023, 145, 334.
- Y. Li, R. Tang, X. Liu, J. Gong, Z. Zhao, Z. Sheng, J. Zhang, X. Li, G. Niu, R. T. K. Kwok, W. Zheng, X. Jiang, B. Z. Tang, ACS Nano 2020, 14, 16840.
- Y. Wang, Y. Li, Z. Zhang, L. Wang, D. Wang, B. Z. Tang, Adv. Mater. 2021, 33, 2103748.
- S. Gao, G. Wei, S. Zhang, B. Zheng, J. Xu, G. Chen, M. Li, S. Song, W. Fu, Z. Xiao, W. Lu, Nat. Commun. 2019, 10, 1.
- W. Xu, D. Wang, B. Z. Tang, Angew. Chem. Inter. Ed. 2021, 60, 7476.
- B. Guo, Z. Sheng, D. Hu, C. Liu, H. Zheng, B. Liu, Adv. Mater. 2018, 30, 1802591.
- X. He, Y. Luo, Y. Li, Y. Pan, R. T. K. Kwok, L. He, X. Duan, P. Zhang, A. Wu, B. Z. Tang, J. Li, Aggregate 2024, 5, 396.
- X. Lin, Z. Sun, S. Huang, C. Liu, J. Peng, Y. Li, Y. Xiong, H. Gao, J. Chen, J. Qi, C. Sun, L. Cai, G. Deng, W. Deng, Adv. Funct. Mater. 2024, 34, 2310237.
- J. Zhang, L. Han, H. Wu, Y. Zhong, P. Shangguan, Y. Liu, M. He, H. Sun, C. Song, X. Wang, Y. Liu, J. Wang, L. Zheng, B. Shi, B. Z. Tang, Adv. Sci. 2023, 10, 2206333.
- J. Wang, Y. Liu, M. Morsch, Y. Lu, P. Shangguan, L. Han, Z. Wang, X. Chen, C. Song, S. Liu, B. Shi, B. Z. Tang, Adv. Mater. 2022, 34, 2106082.
- S. Li, Z. Chen, W. Guo, L. Tan, Q. Wu, X. Ren, C. Fu, Q. Wang, Z. Huang, X. Meng, Adv. Funct. Mater. 2024, 34, 2314742.
- P. Zhao, Z. Jin, Q. Chen, T. Yang, D. Chen, J. Meng, X. Lu, Z. Gu, Q. He, Nat. Commun. 2018, 9, 4241.
- X. Yao, B. Yang, J. Xu, Q. He, W. Yang, View 2022, 3, 1.
- C. Xie, D. Cen, Z. Ren, Y. Wang, Y. Wu, X. Li, G. Han, X. Cai, C. Xie, Z. Ren, Y. Wu, X. Li, G. Han, D. Cen, Y. Wang, X. Cai, Adv. Sci. 2020, 7, 1903512.
- F. Cai, H. Xu, N. Cao, X. Zhang, J. Liu, Y. Lu, J. Chen, Y. Yang, J. Cheng, Z.-C. Hua, H. Zhuang, Cell Death. Dis. 2020, 11, 33.
- J. Zhou, M. Li, Y. Hou, Z. Luo, Q. Chen, H. Cao, R. Huo, C. Xue, L. Sutrisno, L. Hao, Y. Cao, H. Ran, L. Lu, K. Li, K. Cai, ACS Nano 2018, 12, 2858.
- J. Trepel, M. Mollapour, G. Giaccone, L. Neckers, Nat. Rev. Cancer 2010, 10, 537.
- Y. Jiang, J. Zhang, F. Meng, Z. Zhong, ACS Nano 2018, 12, 11070.
- D. Zhang, S. Tian, Y. Liu, M. Zheng, X. Yang, Y. Zou, B. Shi, L. Luo, Nat. Commun. 2022, 13, 6835.
- L.-S. Lin, T. Huang, J. Song, X.-Y. Ou, Z. Wang, H. Deng, R. Tian, Y. Liu, J.-F. Wang, Y. Liu, G. Yu, Z. Zhou, S. Wang, G. Niu, H.-H. Yang, X. Chen, J. Am. Chem. Soc. 2019, 141, 9937.
- J. J. Rennick, A. P. R. Johnston, R. G. Parton, Nat. Nanotechnol. 2021, 16, 266.
- P.-L. Kuo, C.-Y. Chen, Y.-L. Hsu, Cancer Res. 2007, 67, 7406.
- F. M. Walker, L. M. Sobral, E. Danis, B. Sanford, S. Donthula, I. Balakrishnan, D. Wang, A. Pierce, S. D. Karam, S. Kargar, N. J. Serkova, N. K. Foreman, S. Venkataraman, R. Dowell, R. Vibhakar, N. A. Dahl, Nat. Commun. 2024, 15, 4616.
- S. M. Gross, F. Mohammadi, C. Sanchez-Aguila, P. J. Zhan, T. A. Liby, M. A. Dane, A. S. Meyer, L. M. Heiser, Nat. Commun. 2023, 14, 3450.
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Xiang, D., Wang, Z., Zheng, H., Tang, Y., & Li, Q. (2026) · Light: Science & Applications · doi:10.1038/s41377-026-02212-w · Cited by 22 · see citing works
“23b) 234 .”
Bai, Y., Zhang, C., Wu, Z., Jing, H., Zhao, X., Zhang, A., Shi, P., & Zhang, S. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.5c05448 · Cited by 7 · see citing works
Tripartite Cascading Functions of Ultrathin RhMo Nanozymes in Tumor Catalytic Therapy
Li, A., Zhao, T., Yuan, M., He, Y., Tu, W., Zhang, X., Gao, D., Su, J., Jiang, X., & Xue, W. (2026) · Advanced Functional Materials · doi:10.1002/adfm.202532065 · Cited by 4 · see citing works
Guo, H., Shao, Z., Wang, G., Cheng, Y., & Zhang, S. (2025) · Nano Letters · doi:10.1021/acs.nanolett.5c04383 · Cited by 4 · see citing works
Shi, S. Q., Cao, Y., Zuo, J., Li, Q., Zeng, X., Du, J., Fan, J., Sun, W. C., & Peng, X. (2026) · Smart Molecules · doi:10.1002/smo2.70073 · Cited by 1 · see citing works
Wang, H., Guo, L., Li, J., Zhang, C., Gao, Y., Ma, J., Xiong, J., Huang, S., Wu, Q., Wang, J., et al. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.180704 · Cited by 1 · see citing works
NIR‐II Light‐Activated Nanoplatform for Synergistic Photothermal and H 2 S‐Mediated Thrombolysis
Chen, L., Song, J., Shen, Z., & Qi, J. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.202505802
Chu, T., Fan, M., Guo, Y., Liu, M.-L., Tan, M., Deng, X., & Zhao, Z. (2026) · Materials Chemistry Frontiers · doi:10.1039/d5qm00815h
Wu, H., Zhang, J., Huang, X., Zhang, B., Xie, Y., Li, Q., Yang, L., Wu, W., Zheng, Z., Huang, Z., et al. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04581-1
Self-citationLi, Y., Xu, S., Wang, G., Song, Z., Zhang, S., Dai, X., & Wang, S. (2026) · ACS Nano · doi:10.1021/acsnano.6c06383
Chen, Y., Zhao, Y., Tang, L., Zhu, L., Li, X., Luo, X. Y., Zhang, W., 喻兆阳, Liu, F., Tang, B. Z., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-9660011/v1
Self-citationYang, S., Gao, W., Yu, X., Wang, H. T., Ao, G., Ye, T., Wang, H. T., Du, H., Zhang, Y., Li, D., et al. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.71437
Liu, W.-C., Wang, Y., Hao, X., Wang, Y., Zhang, X., Zhang, J., Ge, K., & Zhou, G. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04795-3
Li, Z., Zheng, H., Ma, Y., Li, T., Ma, S., Mi, L., Xu, H., Zheng, S., Guo, H., Wang, X., et al. (2026) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2026.119299
- Authors
- Zou, D., Guo, F., Jiang, Q., Liang, G., Meng, Z., Bao, Z., Lu, X., Pan, M., Zou, C., Xie, J., Ling, G., Zhang, T., Shangguan, P., Ning, S., & Tang, B. Z.
- Affiliations
- Guangxi Medical University (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Guangzhou Medical University Cancer Hospital (CN)
- Capital Medical University (CN)
- Chinese University of Hong Kong (HK)
- Corresponding author
- Shangguan, Ping
- Ning, Shipeng
- Tang, Ben Zhong
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2025-05-29
- Volume
- 35
- Issue
- 46
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W4410906486
- Cited by
- 13
- References
- 45
- Citations by year
- 2026: 11 · 2025: 2
- FWCI
- 3.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Advanced Functional Materials (publishedVersion)
- Rare & Special e-Zone (The Hong Kong University of Science and Technology) (submittedVersion)
- Funders
- National Natural Science Foundation of China (82303797, 82473348, 52303224, 52333007)
- National Key Research and Development Program of China (2023YFB3810001)
- Science, Technology and Innovation Commission of Shenzhen Municipality (KQTD20210811090142053)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
- Health Sciences › Medicine › Genetics › Glioma Diagnosis and Treatment
- Keywords
- photothermal therapy, glioblastoma, gas release, NIR-II imaging, aggregation-induced emission, heat tolerance, mitochondrial dysfunction, apoptosis, HSP90, ATP depletion, brain tumor imaging, orthotopic glioma, synergistic therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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