The DOI matches its Crossref record; 397 of the 397 references it cites were found in a registry or an index.
Tailoring Materials for Modulation of Macrophage Fate
Open accessAbstract
Human immune system acts as a pivotal role in the tissue homeostasis and disease progression. Immunomodulatory biomaterials that can manipulate innate immunity and adaptive immunity hold great promise for a broad range of prophylactic and therapeutic purposes. This review is focused on the design strategies and principles of immunomodulatory biomaterials from the standpoint of materials science to regulate macrophage fate, such as activation, polarization, adhesion, migration, proliferation, and secretion. It offers a comprehensive survey and discussion on the tunability of material designs regarding physical, chemical, biological, and dynamic cues for modulating macrophage immune response. The range of such tailorable cues encompasses surface properties, surface topography, materials mechanics, materials composition, and materials dynamics. The representative immunoengineering applications selected herein demonstrate how macrophage‐immunomodulating biomaterials are being exploited for cancer immunotherapy, infection immunotherapy, tissue regeneration, inflammation resolution, and vaccination. A perspective on the future research directions of immunoregulatory biomaterials is also provided.
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Cites
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Li, Y., Yang, L., Hou, Y., Zhang, Z., Chen, M., Wang, M., Liu, J., Wang, J., Zhao, Z., Xie, C., et al. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.03.021 · Cited by 280
Wang, T., Bai, J., Lu, M., Huang, C., Geng, D., Chen, G., Wang, L., Qi, J., Cui, W., & Deng, L. (2022) · Nature Communications · doi:10.1038/s41467-021-27816-1 · Cited by 221
Morandini, L., Avery, D., Angeles, B., Winston, P., Martin, R. K., Donahue, H. J., & Olivares-Navarrete, R. (2023) · Acta Biomaterialia · doi:10.1016/j.actbio.2023.05.016 · Cited by 40
Investigating Immunomodulatory Biomaterials for Preventing the Foreign Body Response
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Metadata
- Authors
- Li, J., Jiang, X., Li, H., Gelinsky, M., & Gu, Z.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2021-02-09
- Volume
- 33
- Issue
- 12
- Pages
- e2004172-e2004172
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W3128308879
- Cited by
- 403
- References
- 397
- FWCI
- 18.15
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
