The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Actimetric evidence that CLOCK 3111 T/C SNP influences sleep and activity patterns in patients affected by bipolar depression
Abstract
Depressive insomnia and diurnal fluctuations of mood and activity are core clinical features of mood disorders. Here we studied the effect of CLOCK 3111 T/C SNP (rs1801260) on the actimetric recorded diurnal activity and nocturnal sleep of 39 bipolar depressed inpatients. Compared to T/T homozygotes, carriers of the C allele had a similar degree of severity of depression, but showed higher activity levels in the evening, a delayed sleep onset (mean 79 min later), and a reduced amount of sleep during the night (mean 75 min less). Ongoing lithium treatment significantly interacted with rs1801260 by enhancing activity levels in the evening and reducing the differences among genotype groups. Individual characteristics of the molecular clock can influence sleep symptoms in mood disorders. © 2007 Wiley‐Liss, Inc.
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Self-citationInsomnia improvement during antidepressant treatment andCLOCK gene polymorphism
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Chronotype and circadian rhythm in bipolar disorder: A systematic review
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Genome-wide association scan for five major dimensions of personality
Terracciano, A., Sanna, S., Uda, M., Deiana, B., Usala, G., Busonero, F., Maschio, A., Scally, M., Patriciu, N., Chen, W.-M., et al. (2010) · Molecular Psychiatry · doi:10.1038/mp.2008.113 · Cited by 286
Metadata
- Authors
- Benedetti, F., Dallaspezia, S., Fulgosi, M. C., Lorenzi, C., Serretti, A., Barbini, B., Colombo, C., & Smeraldi, E.
- Venue
- American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
- Publisher
- Wiley
- Published
- 2007-01-12
- Volume
- 144B
- Issue
- 5
- Pages
- 631-635
- ISSN
- 1552-4841 (ISSN-L)
- 1552-485X
- OpenAlex
- W2065080899
- Cited by
- 204
- References
- 8
- FWCI
- 6.24
- Type
- journal article
- Language
- en
- Open access
- closed
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- Benedetti, F., Dallaspezia, S., Fulgosi, M. C., Lorenzi, C., Serretti, A., Barbini, B., Colombo, C., & Smeraldi, E. (2007). Actimetric evidence that CLOCK 3111 T/C SNP influences sleep and activity patterns in patients affected by bipolar depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. https://doi.org/10.1002/ajmg.b.30475
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