A functional polymorphism of the OXTR gene is associated with autistic traits in Caucasian and Asian populations
Abstract
There is increasing evidence for associations between polymorphisms of the oxytocin receptor (OXTR) gene and autism spectrum disorder, but to date no study has established links with autistic traits in healthy subjects and potential cultural differences. The present research firstly investigated associations between three widely studied OXTR SNPs and autistic and empathic traits (rs53576 (G/A); rs2254298 (G/A); rs2268498 (T/C)) in two independent studies on male and female Caucasian (n = 537) and Chinese students (n = 280). Autistic and empathic traits were measured in all subjects in the two independent groups using the Autism -Spectrum Quotient (AQ) and the Interpersonal Reactivity Index (IRI) respectively, together with their sub-scales. For both sites, genotyping of the OXTR SNPs was conducted on buccal swab samples using a Cobas Z 480 Light Cycler following automated DNA extraction. Associations at the genotype level with autism trait scores were found in Caucasian subjects for rs2268498 only, with TT carriers having the lowest AQ scores compared with those carrying at least one C-allele. This finding was independently replicated in the Chinese sample although a smaller proportion carried the C-allele compared with the Caucasian sample. Some minor associations were found between empathy trait scores and the three SNPs but were not consistent between the samples. These findings show for the first time that the rs2268498 SNP localized in the promoter flanking region of the OXTR gene is associated with autistic traits in different ethnic/cultural groups. This provides further support for the role of the OXTR gene in relation to autism.
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In the Chinese study cohort, there were no sex differences in EE, trait empathy, or trait autism scores.
“there were no sex-differences in EE, trait empathy (Wu et al., 2012) or trait autism (Kawamura et al., 2011; Montag et al., 2017) scores in our Chinese study cohort”
From Oxytocin Enhancement of Emotional Empathy: Generalization Across Cultures and Effects on Amygdala Activity (2018) · cites this paper as Montag et al., 2017
Cites
Measuring individual differences in empathy: Evidence for a multidimensional approach.
Davis, M. H. (1983) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.44.1.113 · Cited by 10,272 · see citing works
Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1005653411471 · Cited by 6,450 · see citing works
Baron-Cohen, S., & Wheelwright, S. (2004) · Journal of Autism and Developmental Disorders · doi:10.1023/b:jadd.0000022607.19833.00 · Cited by 4,093 · see citing works
Sex differences in empathy and related capacities.
Eisenberg, N., & Lennon, R. (1983) · Psychological Bulletin · doi:10.1037/0033-2909.94.1.100 · Cited by 1,310 · see citing works
Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders.
Guastella, A. J., Einfeld, S. L., Gray, K. M., Rinehart, N. J., Tonge, B. J., Lambert, T. J., & Hickie, I. B. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.020 · Cited by 962 · see citing works
Ruzich, E., Allison, C. L., Smith, P. L., Watson, P., Bonnie Auyeung, B., RING, H. A., & Baron‐Cohen, S. (2015) · Molecular Autism · doi:10.1186/2040-2392-6-2 · Cited by 612 · see citing works
Tost, H., Kolachana, B., Hakimi, S., Lemaitre, H., Verchinski, B. A., Mattay, V. S., Weinberger, D. R., & Meyer–Lindenberg, A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1003296107 · Cited by 564 · see citing works
Positive Association of the Oxytocin Receptor Gene (OXTR) with Autism in the Chinese Han Population
Wu, S., Jia, M., Ruan, Y., Liu, J., Guo, Y., Mei, S., Gong, X., Zhang, Y., Yang, X., & Zhang, D. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.03.013 · Cited by 553 · see citing works
The Autism-Spectrum Quotient (AQ)—Adolescent Version
Baron-Cohen, S., Hoekstra, R. A., Knickmeyer, R., & Wheelwright, S. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0073-6 · Cited by 546 · see citing works
Wheelwright, S., Baron-Cohen, S., Goldenfeld, N., Delaney, J., Fine, D., Smith, R. J. H., Weil, L., & Wakabayashi, A. (2006) · Brain Research · doi:10.1016/j.brainres.2006.01.012 · Cited by 493 · see citing works
Austin, E. J. (2005) · Personality and Individual Differences · doi:10.1016/j.paid.2004.04.022 · Cited by 435 · see citing works
Anagnostou, E., Soorya, L., Chaplin, W., Bartz, J., Halpern, D., Wasserman, S., Wang, A. T., Pepa, L., Tanel, N., Kushki, A., et al. (2012) · Molecular Autism · doi:10.1186/2040-2392-3-16 · Cited by 350 · see citing works
Yatawara, C. J., Einfeld, S. L., Hickie, I. B., Davenport, T. A., & Guastella, A. J. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.162 · Cited by 344 · see citing works
The oxytocin receptor gene (OXTR) is associated with autism spectrum disorder: a meta-analysis
LoParo, D., & Waldman, I. D. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.77 · Cited by 343 · see citing works
Kim, H. S., Sherman, D. K., Sasaki, J. Y., Xu, J., Chu, T. Q., Ryu, C., Suh, E. M., Graham, K., & Taylor, S. E. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010830107 · Cited by 341 · see citing works
Oxytocin improves specific recognition of positive facial expressions
Marsh, A. A., Yu, H. H., Pine, D. S., & Blair, R. J. R. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1780-4 · Cited by 321 · see citing works
The contributions of oxytocin and vasopressin pathway genes to human behavior
Ebstein, R. P., Knafo, A., Mankuta, D., Chew, S. H., & Lai, P. S. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.014 · Cited by 283 · see citing works
Oxytocin, stress and social behavior: neurogenetics of the human oxytocin system
Kumsta, R., & Heinrichs, M. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.09.004 · Cited by 265 · see citing works
Validation of the Interpersonal Reactivity Index in a Chinese Context
Siu, A. M. H., & Shek, D. T. L. (2005) · Research on Social Work Practice · doi:10.1177/1049731504270384 · Cited by 241 · see citing works
Guastella, A. J., & Hickie, I. B. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.06.028 · Cited by 223 · see citing works
The association between oxytocin receptor gene polymorphism (OXTR) and trait empathy
Wu, N., Li, Z., & Su, Y. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.01.009 · Cited by 221 · see citing works
A sociability gene? Meta-analysis of oxytocin receptor genotype effects in humans
Bakermans‐Kranenburg, M. J., & van IJzendoorn, M. H. (2013) · Psychiatric Genetics · doi:10.1097/ypg.0b013e3283643684 · Cited by 217 · see citing works
The effect of intranasal administration of oxytocin on fear recognition
Fischer-Shofty, M., Shamay-Tsoory, S. G., Harari, H., & Levkovitz, Y. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.09.003 · Cited by 184 · see citing works
Oxytocin increases recognition of masked emotional faces
Schulze, L., Lischke, A., Greif, J., Herpertz, S. C., Heinrichs, M., & Domes, G. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.03.011 · Cited by 180 · see citing works
Uzefovsky, F., Shalev, I., Israel, S., Edelman, S., Raz, Y., Mankuta, D., Knafo-Noam, A., & Ebstein, R. P. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2014.11.007 · Cited by 131 · see citing works
Luo, S., Ma, Y., Liu, Y., Li, B., Wang, C., Shi, Z., Li, X., Zhang, W., Rao, Y., & Han, S. (2015) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsv019 · Cited by 111 · see citing works
A Cross-Cultural Comparison of Autistic Traits in the UK, India and Malaysia
Freeth, M., Sheppard, E., Ramachandran, R., & Milne, E. (2013) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-013-1808-9 · Cited by 108 · see citing works
Christ, C. C., Carlo, G., & Stoltenberg, S. F. (2014) · Journal of Personality · doi:10.1111/jopy.12152 · Cited by 81 · see citing works
Oxytocin and Vasopressin Receptor Gene Polymorphisms: Role in Social and Psychiatric Traits
Aspé-Sánchez, M., Moreno, M., Rivera, M. I., Rossi, A., & Ewer, J. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00510 · Cited by 68 · see citing works
Walter, N. T., Montag, C., Markett, S. A., Felten, A., Voigt, G., & Reuter, M. (2012) · Brain and Cognition · doi:10.1016/j.bandc.2012.01.003 · Cited by 63 · see citing works
Yamasue, H. (2012) · Brain and Development · doi:10.1016/j.braindev.2012.08.010 · Cited by 57 · see citing works
Laursen, H. R., Siebner, H. R., Haren, T., Madsen, K., Grønlund, R., Hulme, O., & Henningsson, S. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00423 · Cited by 56 · see citing works
A comprehensive meta-analysis of common genetic variants in autism spectrum conditions
Warrier, V., Chee, V., Smith, P. L., Chakrabarti, B., & Baron‐Cohen, S. (2015) · Molecular Autism · doi:10.1186/s13229-015-0041-0 · Cited by 50 · see citing works
Kranz, T. M., Kopp, M., Waltes, R., Sachse, M., Duketis, E., Jarczok, T. A., Degenhardt, F., Görgen, K., Meyer, J., Freitag, C. M., et al. (2016) · Autism Research · doi:10.1002/aur.1597 · Cited by 46 · see citing works
Primal emotional-affective expressive foundations of human facial expression
Montag, C., & Panksepp, J. (2016) · Motivation and Emotion · doi:10.1007/s11031-016-9570-x · Cited by 43 · see citing works
Relationship between oxytocin receptor genotype and recognition of facial emotion.
Melchers, M., Montag, C., Markett, S. A., & Reuter, M. (2013) · Behavioral Neuroscience · doi:10.1037/a0033748 · Cited by 41 · see citing works
The Oxytocin Receptor Gene ( OXTR ) and Face Recognition
Verhallen, R. J., Bosten, J. M., Goodbourn, P. T., Lawrance-Owen, A. J., Bargary, G., & Mollon, J. D. (2016) · Psychological Science · doi:10.1177/0956797616672269 · Cited by 25 · see citing works
The oxytocin receptor gene and social perception
Melchers, M., Montag, C., Felten, A., & Reuter, M. (2015) · Social Neuroscience · doi:10.1080/17470919.2015.1008646 · Cited by 21 · see citing works
O’Connell, G., Whalley, H. C., Mukherjee, P., Stanfield, A. C., Montag, C., Hall, J., & Reuter, M. (2012) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2012.21007 · Cited by 17 · see citing works
Kawamura, Y., Liu, X., Shimada, T., Otowa, T., Kakiuchi, C., Akiyama, T., Umekage, T., & Sasaki, T. (2011) · Asia-Pacific Psychiatry · doi:10.1111/j.1758-5872.2011.00132.x · Cited by 7 · see citing works
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- Authors
- Montag, C., Sindermann, C., Melchers, M., Jung, S., Luo, R., Becker, B., Xie, J., Xu, W., Guastella, A. J., & Kendrick, K. M.
- Affiliations
- University of Electronic Science and Technology of China (CN)
- Universität Ulm (DE)
- University of Bonn (DE)
- Third People's Hospital of Chengdu (CN)
- Chinese University of Hong Kong (HK)
- The University of Sydney (AU)
- Corresponding author
- Montag, Christian
- Kendrick, Keith M.
- ORCID
- Venue
- American Journal of Medical Genetics Part B Neuropsychiatric Genetics
- Publisher
- Wiley
- Published
- 2017-10-13
- Volume
- 174
- Issue
- 8
- Pages
- 808-816
- ISSN
- 1552-4841 (ISSN-L)
- 1552-485X
- OpenAlex
- W2763124390
- Cited by
- 50
- References
- 40
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 1 · 2022: 5 · 2021: 4 · 2020: 10 · 2019: 8 · 2018: 14 · 2017: 1
- FWCI
- 5.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Medical Genetics Part B Neuropsychiatric Genetics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (31530032)
- Deutsche Forschungsgemeinschaft (MO 2363/2‐1, MO 2363/3‐1)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- oxytocin receptor gene, oxytocin receptor, autism spectrum disorder, autistic traits, empathy, single nucleotide polymorphisms, promoter, rs53576, rs2254298, genetic association, ethnic differences, Caucasian population, Chinese population
- MeSH terms
- Adult, Alleles, Autistic Disorder, Female, Genotype, Humans, Male, Linkage Disequilibrium, Case-Control Studies, Receptors, Oxytocin, Quantitative Trait, Heritable, Polymorphism, Single Nucleotide, White People, Asian People, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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