Culture, distress, and oxytocin receptor polymorphism (OXTR) interact to influence emotional support seeking
Open accessAbstract
Research has demonstrated that certain genotypes are expressed in different forms, depending on input from the social environment. To examine sensitivity to cultural norms regarding emotional support seeking as a type of social environment, we explored the behavioral expression of oxytocin receptor polymorphism (OXTR) rs53576, a gene previously related to socio-emotional sensitivity. Seeking emotional support in times of distress is normative in American culture but not in Korean culture. Consequently, we predicted a three-way interaction of culture, distress, and OXTR genotype on emotional support seeking. Korean and American participants (n = 274) completed assessments of psychological distress and emotional support seeking and were genotyped for OXTR. We found the predicted three-way interaction: among distressed American participants, those with the GG/AG genotypes reported seeking more emotional social support, compared with those with the AA genotype, whereas Korean participants did not differ significantly by genotype; under conditions of low distress, OXTR groups did not differ significantly in either cultural group. These findings suggest that OXTR rs53576 is sensitive to input from the social environment, specifically cultural norms regarding emotional social support seeking. These findings also indicate that psychological distress and culture are important moderators that shape behavioral outcomes associated with OXTR genotypes.
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Men and women homozygous for the A allele of rs53576 reported seeking less emotional social support.
“men and women homozygous for the A allele reported seeking less emotional social support (Kim et al., 2010).”
From Vasopressin and oxytocin receptor systems in the brain: Sex differences and sex-specific regulation of social behavior (2016) · cites this paper as Kim et al., 2010
The OXT receptor (rs53576) polymorphism is associated with emotional social support seeking in Americans but not in Koreans.
“A recent genetic study has also reported that while the OXT receptor (rs53576) polymorphism is associated with emotional social support seeking in Americans, it is not in Koreans [Kim et al., 2010].”
From Oxytocin blurs the self-other distinction during trait judgments and reduces medial prefrontal cortex responses: Oxytocin Blurs Self-Other Distinction (2016) · cites this paper as Kim et al., 2010
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Cites
A Global Measure of Perceived Stress
Cohen, S., Kamarck, T., & Mermelstein, R. (1983) · Journal of Health and Social Behavior · doi:10.2307/2136404 · Cited by 32,807 · see citing works
Assessing coping strategies: A theoretically based approach.
Carver, C. S., Scheier, M. F., & Weintraub, J. K. (1989) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.56.2.267 · Cited by 11,682 · see citing works
Assessing coping strategies: A theoretically based approach.
Carver, C. S., Scheier, M. F., & Weintraub, J. K. (1989) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.56.2.267 · Cited by 11,507 · see citing works
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120 · see citing works
Culture and the Evolutionary Process
Griesemer, J. R., Boyd, R. T., & Richerson, P. J. (1986) · Ornithological Applications · doi:10.2307/1367778 · Cited by 7,133 · see citing works
Social Relationships and Health
House, J. S., Landis, K. R., & Umberson, D. (1988) · Science · doi:10.1126/science.3399889 · Cited by 7,073 · see citing works
Role of genotype in the cycle of violence in maltreated children
Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., Taylor, A., & Poulton, R. (2002) · Science · doi:10.1126/science.1072290 · Cited by 4,842 · see citing works
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690 · see citing works
The oxytocin receptor system: structure, function, and regulation
Gimpl, G., & Fahrenholz, F. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.2.629 · Cited by 3,089 · see citing works
Oxytocin improves “mind-reading” in humans
Domes, G., Heinrichs, M., Michel, A., Berger, C., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.015 · Cited by 1,298 · see citing works
Kim, H. S., Sherman, D. K., & Taylor, S. E. (2008) · American Psychologist · doi:10.1037/0003-066x · Cited by 1,252 · see citing works
Self-citationCulture and Social Support: Who Seeks It and Why?
Taylor, S. E., Sherman, D. K., Kim, H. S., Jarcho, J. M., Takagi, K., & Dunagan, M. S. (2004) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.87.3.354 · Cited by 974 · see citing works
Self-citationMeaney, M. J., & Szyf, M. (2005) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2005.7.2/mmeaney · Cited by 958 · see citing works
Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans
Rodrigues, S. M., Saslow, L. R., Garcia, N., John, O. P., & Keltner, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909579106 · Cited by 812 · see citing works
Culture–gene coevolution of individualism–collectivism and the serotonin transporter gene
Chiao, J. Y., & Blizinsky, K. D. (2009) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2009.1650 · Cited by 672 · see citing works
Positive Association of the Oxytocin Receptor Gene (OXTR) with Autism in the Chinese Han Population
Wu, S., Jia, M., Ruan, Y., Liu, J., Guo, Y., Mei, S., Gong, X., Zhang, Y., Yang, X., & Zhang, D. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.03.013 · Cited by 553 · see citing works
Neural pathways link social support to attenuated neuroendocrine stress responses
Eisenberger, N. I., Taylor, S. E., Gable, S. L., Hilmert, C. J., & Lieberman, M. D. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.01.038 · Cited by 543 · see citing works
Self-citationBakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2006) · Developmental Psychobiology · doi:10.1002/dev.20152 · Cited by 526 · see citing works
Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2008) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsn004 · Cited by 474 · see citing works
Kitayama, S. (2002) · Psychological Bulletin · doi:10.1037/0033-2909.128.1.89 · Cited by 465 · see citing works
Gelernter, J. E., Kranzler, H. R., & Cubells, J. F. (1997) · Human Genetics · doi:10.1007/s004390050624 · Cited by 435 · see citing works
Taylor, S. E., Way, B. M., Welch, W. T., Hilmert, C. J., Lehman, B. J., & Eisenberger, N. I. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.019 · Cited by 432 · see citing works
Self-citationPursuit of Comfort and Pursuit of Harmony: Culture, Relationships, and Social Support Seeking
Kim, H. S., Sherman, D. K., Ko, D. M., & Taylor, S. E. (2006) · Personality and Social Psychology Bulletin · doi:10.1177/0146167206291991 · Cited by 424 · see citing works
Self-citationTaylor, S. E., Welch, W. T., Kim, H. S., & Sherman, D. K. (2007) · Psychological Science · doi:10.1111/j.1467-9280.2007.01987.x · Cited by 423 · see citing works
Self-citationMoffitt, T. E., Caspi, A., & Rutter, M. (2006) · Perspectives on Psychological Science · doi:10.1111/j.1745-6916.2006.00002.x · Cited by 389 · see citing works
Oxytocin receptor polymorphisms and adult attachment style in patients with depression
Costa, B., Pini, S., Gabelloni, P., Abelli, M., Lari, L., Cardini, A., Muti, M., Gesi, C., Landi, S., Galderisi, S., et al. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.05.006 · Cited by 282 · see citing works
Lucht, M. J., Barnow, S., Sonnenfeld, C., Rosenberger, A., Grabe, H. J., Schroeder, W., Völzke, H., Freyberger, H. J., Herrmann, F. H., Kroemer, H., et al. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.04.004 · Cited by 271 · see citing works
Strobel, A., Gutknecht, L., Rothe, C., Reif, A., M�ssner, R., Zeng, Y., Brocke, B., & Lesch, K. (2003) · Journal of Neural Transmission · doi:10.1007/s00702-003-0072-0 · Cited by 228 · see citing works
Social Regulation of Human Gene Expression
Cole, S. W. (2009) · Current Directions in Psychological Science · doi:10.1111/j.1467-8721.2009.01623.x · Cited by 187 · see citing works
Social support, depressed mood, and adjustment to stress: A genetic epidemiologic investigation.
Kessler, R. C., Kendler, K. S., Heath, A. C., Neale, M. C., & al, E. (1992) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.62.2.257 · Cited by 162 · see citing works
Obradović, J., & Boyce, W. T. (2009) · Developmental Neuroscience · doi:10.1159/000216541 · Cited by 134 · see citing works
Social support, depressed mood, and adjustment to stress: A genetic epidemiologic investigation.
Kessler, R. C., Kendler, K. S., Heath, A. C., Neale, M. C., & Eaves, L. J. (1992) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.62.2.257 · Cited by 132 · see citing works
Genetic and Environmental Influences on Coping Styles
Busjahn, A., Faulhaber, H., Freier, K., & Luft, F. C. (1999) · Psychosomatic Medicine · doi:10.1097/00006842-199907000-00011 · Cited by 83 · see citing works
Culture, serotonin receptor polymorphism and locus of attention
Kim, H. S., Sherman, D. K., Taylor, S. E., Sasaki, J. Y., Chu, T. Q., Ryu, C., Suh, E. M., & Xu, J. (2009) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsp040 · Cited by 79 · see citing works
Self-citationSocial Influences on Health: Is Serotonin a Critical Mediator?
Way, B. M., & Taylor, S. E. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181ce6a7d · Cited by 75 · see citing works
Self-citationA developmental-contextual model of depressive symptoms in Mexican-origin female adolescents.
Bámaca‐Colbert, M. Y., Umaña‐Taylor, A. J., & Gayles, J. G. (2011) · Developmental Psychology · doi:10.1037/a0025666 · Cited by 69 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- [26]Derogatis LR, Spencer PM. Brief Symptom Inventory: Administration, Scoring, and Procedures Manual-I. Baltimore: Clinical Psychometric Research; 1982. [Google Scholar]
- [32]Lumsden CJ, Wilson EO. Genes, Mind, & Culture. Cambridge, MA: Harvard University Press; 1981. [Google Scholar]
Cited by
Sorted by citations
Social effects of oxytocin in humans: context and person matter
Bartz, J. A., Zaki, J., Bolger, N., & Ochsner, K. N. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.05.002 · Cited by 1,572 · see citing works
The oxytocin receptor: from intracellular signaling to behavior
Jurek, B., & Neumann, I. D. (2018) · Physiological Reviews · doi:10.1152/physrev.00031.2017 · Cited by 999 · see citing works
Neumann, I. D., & Landgraf, R. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2012.08.004 · Cited by 954 · see citing works
Oxytocin and social affiliation in humans
Feldman, R. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.01.008 · Cited by 767 · see citing works
Dumais, K. M., & Veenema, A. H. (2016) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2015.04.003 · Cited by 520 · see citing works
“Further, men and women homozygous for the A allele reported seeking less emotional social support (Kim et al., 2010).”
BackgroundSensitive Parenting Is Associated with Plasma Oxytocin and Polymorphisms in the OXTR and CD38 Genes
Feldman, R., Zagoory-Sharon, O., Weisman, O., Schneiderman, I., Gordon, I., Maoz, R., Shalev, I., & Ebstein, R. P. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.12.025 · Cited by 393 · see citing works
Feldman, R., Monakhov, M., Pratt, M., & Ebstein, R. P. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.08.008 · Cited by 352 · see citing works
Genetics of Human Social Behavior
Ebstein, R. P., Israel, S., Chew, S. H., Zhong, S., & Knafo, A. (2010) · Neuron · doi:10.1016/j.neuron.2010.02.020 · Cited by 323 · see citing works
Psychobiology of social support: The social dimension of stress buffering
Ditzen, B., & Heinrichs, M. (2014) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-139008 · Cited by 298 · see citing works
The contributions of oxytocin and vasopressin pathway genes to human behavior
Ebstein, R. P., Knafo, A., Mankuta, D., Chew, S. H., & Lai, P. S. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.014 · Cited by 283 · see citing works
Kogan, A., Saslow, L. R., Impett, E. A., Oveis, C., Keltner, D., & Rodrigues Saturn, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1112658108 · Cited by 279 · see citing works
Oxytocin receptor gene ( <i>OXTR</i> ) is related to psychological resources
Saphire-Bernstein, S., Way, B. M., Kim, H. S., Sherman, D. K., & Taylor, S. E. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113137108 · Cited by 262 · see citing works
Parker, K. J., Garner, J. P., Libove, R. A., Hyde, S. A., Hornbeak, K. B., Carson, D. S., Liao, C.-P., Phillips, J. M., Hallmayer, J. F., & Hardan, A. Y. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402236111 · Cited by 215 · see citing works
Bradley, B., Westen, D., Mercer, K. B., Binder, E. B., Jovanovic, T., Crain, D., Wingo, A., & Heim, C. (2011) · Development and Psychopathology · doi:10.1017/s0954579411000162 · Cited by 213 · see citing works
Variation in the Oxytocin Receptor Gene Is Associated with Pair-Bonding and Social Behavior
Walum, H., Lichtenstein, P., Neiderhiser, J. M., Reiss, D., Ganiban, J. M., Spotts, E. L., Pedersen, N. L., Anckarsäter, H., Larsson, H., & Westberg, L. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.09.002 · Cited by 211 · see citing works
Oxytocin receptor genetic variation promotes human trust behavior
Krueger, F., Parasuraman, R., Iyengar, V., Thornburg, M., Weel, J., Lin, M., Clarke, E., McCabe, K., & Lipsky, R. H. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00004 · Cited by 207 · see citing works
“In contrast, other studies combined the GG/AG groups and demonstrated that individuals with the GG/AG genotypes (compared with those with the AA genotype) seek more emotional social support (Kim et al., 2010) and show higher positive affect (Lucht et al., 2009).”
Smith, K. E., Porges, E. C., Norman, G. J., Connelly, J. J., & Decety, J. (2014) · Social Neuroscience · doi:10.1080/17470919.2013.863223 · Cited by 195 · see citing works
Oxytocin improves behavioural and neural deficits in inferring others’ social emotions in autism
Aoki, Y., Yahata, N., Watanabe, T., Takano, Y., Kawakubo, Y., Kuwabara, H., Iwashiro, N., Natsubori, T., Inoue, H., Suga, M., et al. (2014) · Brain · doi:10.1093/brain/awu231 · Cited by 187 · see citing works
Yamasue, H., Yee, J. R., Hurlemann, R., Rilling, J. K., Chen, F. S., Meyer-Lindenberg, A., & Tost, H. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3327-12.2012 · Cited by 149 · see citing works
Oxytocin׳s role in anxiety: A critical appraisal
MacDonald, K., & Feifel, D. (2014) · Brain Research · doi:10.1016/j.brainres.2014.01.025 · Cited by 139 · see citing works
Sex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin
MacDonald, K. S. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00194 · Cited by 119 · see citing works
Overview of human oxytocin research
Kendrick, K. M., Guastella, A. J., & Becker, B. (2017) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2017_19 · Cited by 121 · see citing works
Hormonal contraceptives suppress oxytocin-induced brain reward responses to the partner’s face
Scheele, D., Plota, J., Stoffel-Wagner, B., Maier, W., & Hurlemann, R. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsv157 · Cited by 116 · see citing works
“Interestingly, an OXTR polymorphism has been linked to social support seeking, but the direction of this effect was dependent on cultural norms (Kim et al., 2010).”
BackgroundLuo, S., Ma, Y., Liu, Y., Li, B., Wang, C., Shi, Z., Li, X., Zhang, W., Rao, Y., & Han, S. (2015) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsv019 · Cited by 111 · see citing works
Oxytocin and stress-related disorders: neurobiological mechanisms and treatment opportunities
Sippel, L. M., Allington, C. E., Pietrzak, R. H., Harpaz-Rotem, I., Mayes, L. C., & Olff, M. (2017) · Chronic Stress · doi:10.1177/2470547016687996 · Cited by 99 · see citing works
Aoki, Y., Watanabe, T., Abe, O., Kuwabara, H., Yahata, N., Takano, Y., Iwashiro, N., Natsubori, T., Takao, H., Kawakubo, Y., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.74 · Cited by 95 · see citing works
Oxytocin receptor gene and racial ingroup Bias in empathy-related brain activity
Luo, S., Li, B., Ma, Y., Zhang, W., Rao, Y., & Han, S. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.01.042 · Cited by 85 · see citing works
Geng, Y., Zhao, W., Zhou, F., Ma, X., Yao, S., Hurlemann, R., Becker, B., & Kendrick, K. M. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00512 · Cited by 78 · see citing works
Linking neurogenetics and individual differences in language learning: the dopamine hypothesis.
Wong, P. C. M., Morgan-Short, K., Ettlinger, M., & Zheng, J. (2012) · Cortex · doi:10.1016/j.cortex.2012.03.017 · Cited by 67 · see citing works
Distress of ostracism: oxytocin receptor gene polymorphism confers sensitivity to social exclusion
McQuaid, R. J., McInnis, O. A., Matheson, K., & Anisman, H. (2015) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsu166 · Cited by 67 · see citing works
Zhao, W., Yao, S., Li, Q., Geng, Y., Ma, X., Luo, L., Xu, L., & Kendrick, K. M. (2016) · Human Brain Mapping · doi:10.1002/hbm.23190 · Cited by 65 · see citing works
Smearman, E. L., Winiarski, D. A., Brennan, P. A., Najman, J., & Johnson, K. C. (2015) · Development and Psychopathology · doi:10.1017/s0954579414000649 · Cited by 60 · see citing works
Genetic modulation of oxytocin sensitivity: A pharmacogenetic approach
Chen, F. S., Kumsta, R., Dvorak, F., Domes, G., Yim, O. S., Ebstein, R. P., & Heinrichs, M. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.163 · Cited by 59 · see citing works
Oxytocin and anxiety disorders
Gottschalk, M. G., & Domschke, K. (2017) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2017_25 · Cited by 61 · see citing works
Lucas-Thompson, R. G., & Holman, E. A. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.02.015 · Cited by 51 · see citing works
Montag, C., Sindermann, C., Melchers, M., Jung, S., Luo, R., Becker, B., Xie, J., Xu, W., Guastella, A. J., & Kendrick, K. M. (2017) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32596 · Cited by 50 · see citing works
Huetter, F. K., Bachmann, H. S., Reinders, A., Siffert, D., Stelmach, P., Knop, D., Horn, P. A., & Siffert, W. (2016) · PLOS ONE · doi:10.1371/journal.pone.0160059 · Cited by 50 · see citing works
Genetic and Environmental Multidimensionality of Well- and Ill-Being in Middle Aged Twin Men
Franz, C. E., Panizzon, M. S., Eaves, L. J., Thompson, W., Lyons, M. J., Jacobson, K. C., Tsuang, M., Glatt, S. J., & Kremen, W. S. (2012) · Behavior Genetics · doi:10.1007/s10519-012-9538-x · Cited by 36 · see citing works
Shao, D., Zhang, H.-H., Long, Z.-T., Li, J., Bai, H.-Y., Li, J.-J., & Cao, F.-L. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.06.002 · Cited by 37 · see citing works
Flasbeck, V., Moser, D., Kumsta, R., & Brüne, M. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00359 · Cited by 34 · see citing works
Kushner, S. C., Herzhoff, K., Vrshek‐Schallhorn, S., & Tackett, J. L. (2018) · Aggressive Behavior · doi:10.1002/ab.21724 · Cited by 31 · see citing works
Lee, K. W., Ching, S. M., Ramachandran, V., Tusimin, M., Mohd Nordin, N., Chong, S. C., & Hoo, F. K. (2019) · Genes · doi:10.3390/genes10120988 · Cited by 14 · see citing works
Interactive effects of OXTR and GAD1 on envy-associated behaviors and neural responses
Tanaka, T., Nishimura, F., Kakiuchi, C., Kasai, K., Kimura, M., & Haruno, M. (2019) · PLOS ONE · doi:10.1371/journal.pone.0210493 · Cited by 9 · see citing works
- Authors
- Kim, H. S., Sherman, D. K., Sasaki, J. Y., Xu, J., Chu, T. Q., Ryu, C., Suh, E. M., Graham, K., & Taylor, S. E.
- Affiliations
- University of California, Santa Barbara (US)
- Tufts University (US)
- Yonsei University (KR)
- University of California, Los Angeles (US)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2010-08-19
- Volume
- 107
- Issue
- 36
- Pages
- 15717-15721
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC2936623
- OpenAlex
- W2140989038
- Cited by
- 341
- References
- 36
- Citations by year
- 2025: 4 · 2024: 10 · 2023: 6 · 2022: 19 · 2021: 16 · 2020: 20 · 2019: 18 · 2018: 31 · 2017: 39 · 2016: 34 · 2015: 30 · 2014: 31 · 2013: 28 · 2012: 32
- FWCI
- 36.12
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation (0734230, 0729532)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Social Sciences › Psychology › Social Psychology › Attachment and Relationship Dynamics
- Keywords
- oxytocin receptor, OXTR rs53576, emotional support seeking, psychological distress, cultural norms, gene-environment interaction, Korean culture, American culture, social support
- MeSH terms
- Cultural Characteristics, Emotions, Humans, Polymorphism, Genetic, Social Support, Stress, Psychological, United States, Receptors, Oxytocin, Republic of Korea
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