Dysexecutive syndrome: diagnostic criteria and validation study
Abstract
OBJECTIVE: Disorders of executive functions are among the most frequent cognitive deficits, but they remain poorly defined and are subject to heterogeneous assessment. To address this major issue, the Groupe de Réflexion sur l'Evaluation des Fonctions Exécutives (GREFEX) group has proposed criteria for behavioral and cognitive dysexecutive syndromes and has designed a battery including a specific heteroquestionnaire and 7 cognitive tests. We investigated the frequency of behavioral and cognitive dysexecutive disorders in patients suffering from various diseases and the association of these disorders with loss of autonomy. METHODS: A total of 461 patients aged between 16 and 90 years with severe traumatic brain injury, stroke, mild cognitive impairment, Alzheimer disease, multiple sclerosis, and Parkinson disease were recruited into this prospective cohort study by 21 centers between September 2003 and June 2006. Behavioral and cognitive dysexecutive disorders were examined using the GREFEX battery. RESULTS: A dysexecutive syndrome was observed in 60% of patients, concerning both behavioral and cognitive domains in 26% and dissociated in 34%. All behavioral and cognitive dysexecutive disorders discriminated (p = 0.001, all) patients from controls. The pattern of cognitive syndrome differed (p = 0.0001) according to the disease. Finally, behavioral (odds ratio [OR], 4.6; 95% confidence interval [CI], 2. 3-9.1; p = 0.0001) and cognitive (OR, 3.36; 95% CI, 1.7-6.6; p = 0.001) dysexecutive syndromes and Mini Mental State Examination score (OR, 0.79; 95% CI, 0.68-0.91; p = 0.002) were independent predictors of loss of autonomy. INTERPRETATION: This study provided criteria of dysexecutive syndrome and showed that both behavioral and cognitive syndromes contribute to loss of autonomy. Profiles vary across patients and diseases, and therefore systematic assessment of behavioral and cognitive disorders in reference to diagnostic criteria is needed.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Cognition is affected early and progresses with disease severity and involves dopaminergic, serotoninergic, noradrenergic, and cholinergic systems.
“Cognition is affected early and progresses with disease severity and involves a number of neurotransmitter systems including dopaminergic, serotoninergic, noradrenergic, and cholinergic 60, 61.”
From Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease (2013) · cites this paper as [61]
Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282 · see citing works
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915 · see citing works
Studies of interference in serial verbal reactions
Stroop, J. R. (1935) · Journal of Experimental Psychology · doi:10.1037/h0054651 · Cited by 18,622 · see citing works
Assessment of Older People: Self-Maintaining and Instrumental Activities of Daily Living
Lawton, M. P., & Brody, E. M. (1969) · The Gerontologist · doi:10.1093/geront/9.3_part_1.179 · Cited by 18,540 · see citing works
Mild Cognitive Impairment: Clinical Characterization and Outcome
Petersen, R. C., Smith, G. E., Waring, S. C., Ivnik, R. J., Tangalos, E. G., & Kokmen, E. (1999) · Archives of Neurology · doi:10.1001/archneur.56.3.303 · Cited by 8,980 · see citing works
VALIDITY OF THE TRAIL MAKING TEST AS AN INDICATOR OF ORGANIC BRAIN DAMAGE
Reitan, R. M. (1958) · Perceptual and Motor Skills · doi:10.2466/pms.1958.8.3.271 · Cited by 7,925 · see citing works
The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia
Cummings, J. L., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D. A., & Gornbein, J. (1994) · Neurology · doi:10.1212/wnl.44.12.2308 · Cited by 7,568 · see citing works
New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
Poser, C. M., Paty, D. W., Scheinberg, L., McDonald, W. I., Davis, F. A., Ebers, G. C., Johnson, K. P., Sibley, W. A., Silberberg, D. H., & Tourtellotte, W. W. (1983) · Annals of Neurology · doi:10.1002/ana.410130302 · Cited by 7,384 · see citing works
McDonald, W. I., Compston, A., Edan, G., Goodkin, D., Hartung, H., Lublin, F. D., McFarland, H. F., Paty, D. W., Polman, C. H., Reingold, S. C., et al. (2001) · Annals of Neurology · doi:10.1002/ana.1032 · Cited by 6,969 · see citing works
Interobserver agreement for the assessment of handicap in stroke patients
van Swieten, J. C., Koudstaal, P. J., Visser, M. C., Schouten, H. J., & van Gijn, J. (1988) · Stroke · doi:10.1161/01.str.19.5.604 · Cited by 6,512 · see citing works
Higher cortical functions in man
Lurii︠a︡, A. R., Teuber, H., Pribram, K. H., & Haigh, B. (1966) · Basic Books · Cited by 2,858 · see citing works
A Modified Card Sorting Test Sensitive to Frontal Lobe Defects
Nelson, H. E. (1976) · Cortex · doi:10.1016/s0010-9452(76)80035-4 · Cited by 2,454 · see citing works
DEFICITS IN STRATEGY APPLICATION FOLLOWING FRONTAL LOBE DAMAGE IN MAN
SHALLICE, T., & BURGESS, P. W. (1991) · Brain · doi:10.1093/brain/114.2.727 · Cited by 2,017 · see citing works
Severe disturbance of higher cognition after bilateral frontal lobe ablation: Patient EVR
Eslinger, P. J., & Damasio, A. R. (1985) · Neurology · doi:10.1212/wnl.35.12.1731 · Cited by 1,426 · see citing works
Dissociation Of Working Memory from Decision Making within the Human Prefrontal Cortex
Bechara, A., Damásio, H., Tranel, D., & Anderson, S. W. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-01-00428.1998 · Cited by 1,059 · see citing works
Standardizing Assessment of Elderly People in Acute Care: The interRAI Acute Care Instrument
Gray, L., Bernabei, R., Berg, K., Finne‐Soveri, H., Fries, B. E., Hirdes, J. P., Jónsson, P. V., Morris, J. N., Steel, K., & Ariño‐Blasco, S. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01590.x · Cited by 967 · see citing works
Impaired social response reversal. A case of 'acquired sociopathy'.
Blair, R., & Cipolotti, L. (2000) · Brain : a journal of neurology · doi:10.1093/brain/123.6.1122 · Cited by 963 · see citing works
A Clinicopathologic Study of 100 Cases of Parkinson's Disease
Hughes, A. J., Daniel, S. E., Blankson, S., & Lees, A. J. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540020018011 · Cited by 945 · see citing works
The Problem of Assessing Executive Functions
Lezak, M. D. (1982) · International Journal of Psychology · doi:10.1080/00207598208247445 · Cited by 827 · see citing works
Cardebat, D., Doyon, B., Puel, M., Goulet, P., & Joanette, Y. (1990) · PubMed · Cited by 698 · see citing works
Baddeley, A., Logie, R. H., Bressi, S., Sala, S. D., & Spinnler, H. R. (1986) · The Quarterly Journal of Experimental Psychology Section A · doi:10.1080/14640748608401616 · Cited by 698 · see citing works
Is there a dysexecutive syndrome?
Stuss, D. T., & Alexander, M. P. (2007) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2007.2096 · Cited by 557 · see citing works
Wisconsin Card Sorting Test Performance as a Measure of Frontal Lobe Damage
Anderson, S. W., Damasio, H., Jones, R., & Tranel, D. (1991) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/01688639108405107 · Cited by 518 · see citing works
Wisconsin card sorting test performance as a measure of frontal lobe damage
(1991) · Neuropsychological Rehabilitation · doi:10.1080/09602019108520169 · Cited by 505 · see citing works
Assessment of global function: The Reintegration to Normal Living Index.
Wood-Dauphinée, S., Opzoomer, M. A., Williams, J., Marchand, B., & Spitzer, W. O. (1988) · PubMed · Cited by 437 · see citing works
Barberger‐Gateau, P., Commenges, D., Gagnon, M., Letenneur, L., Sauvel, C., & Dartigues, J. (1992) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1992.tb01802.x · Cited by 427 · see citing works
Frontal amnesia and the dysexecutive syndrome
Baddeley, A., & Wilson, B. A. (1988) · Brain and Cognition · doi:10.1016/0278-2626(88)90031-0 · Cited by 420 · see citing works
Bizarre Responses, Rule Detection and Frontal Lobe Lesions
Burgess, P. W., & Shallice, T. (1996) · Cortex · doi:10.1016/s0010-9452(96)80049-9 · Cited by 300 · see citing works
Impaired awareness of behavioral limitations after traumatic brain injury.
Prigatano, G. P., & Altman, I. M. (1990) · PubMed · Cited by 265 · see citing works
Frontal syndrome and disorders of executive functions
Godefroy, O. (2003) · Journal of Neurology · doi:10.1007/s00415-003-0918-2 · Cited by 263 · see citing works
Self-citationHigher Cortical Functions in Man
Krieg, W. J. S. (1966) · JAMA · doi:10.1001/jama.1966.03110040111037 · Cited by 185 · see citing works
Control Functions of the Frontal Lobes. Modularity of the Central-Supervisory System?
Godefroy, O., Cabaret, M., Petit-Chenal, V., Pruvo, J.-P., & Rousseaux, M. (1999) · Cortex · doi:10.1016/s0010-9452(08)70782-2 · Cited by 141 · see citing works
Self-citationMRI correlates of executive dysfunction in patients with ischaemic stroke
Vataja, R., Pohjasvaara, T., Mäntylä, R., Ylikoski, R., Leppävuori, A., Leskelä, M., Kalska, H., Hietanen, M., Aronen, H. J., Salonen, O. L. M., et al. (2003) · European Journal of Neurology · doi:10.1046/j.1468-1331.2003.00676.x · Cited by 122 · see citing works
The Behavioral and Cognitive Neurology of Stroke
(2007) · Cambridge University Press eBooks · doi:10.1017/cbo9780511544880 · Cited by 101 · see citing works
Godefroy, O. (1998) · Brain · doi:10.1093/brain/121.8.1545 · Cited by 100 · see citing works
Self-citationAge-Related Slowing: Perceptuomotor, Decision, or Attention Decline?
Godefroy, O., Roussel, M., Despretz, P., Quaglino, V., & Boucart, M. (2010) · Experimental Aging Research · doi:10.1080/03610731003613615 · Cited by 94 · see citing works
Self-citationPérin, B., Godefroy, O., Fall, S., & de Marco, G. (2009) · Brain and Cognition · doi:10.1016/j.bandc.2009.09.010 · Cited by 86 · see citing works
Self-citationBailon, O., Roussel, M., Boucart, M., Krystkowiak, P. C., & Godefroy, O. (2010) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000305095 · Cited by 56 · see citing works
Self-citationSyndromes frontaux et dysexécutifs
Godefroy, O. (2004) · Revue Neurologique · doi:10.1016/s0035-3787(04)71071-1 · Cited by 54 · see citing works
Self-citationDeficit of Episodic Memory: Anatomy and Related Patterns in Stroke Patients
Godefroy, O., Roussel, M., Leclerc, X., & Leys, D. (2009) · European Neurology · doi:10.1159/000197107 · Cited by 51 · see citing works
Self-citationStroke and Action Slowing: Mechanisms, Determinants and Prognosis Value
Godefroy, O., Spagnolo, S., Roussel, M., & Boucart, M. (2010) · Cerebrovascular Diseases · doi:10.1159/000297968 · Cited by 46 · see citing works
Self-citationSRT lengthening: role of an alertness deficit in frontal damaged patients.
Godefroy, O., Lhullier-Lamy, C., & Rousseaux, M. (2002) · Neuropsychologia · doi:10.1016/s0028-3932(02)00109-4 · Cited by 42 · see citing works
Self-citationMotor and cognitive slowing in multiple sclerosis: An attentional deficit?
Stoquart-Elsankari, S., Bottin, C., Roussel, M., & Godefroy, O. (2009) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2009.11.017 · Cited by 33 · see citing works
Self-citationGodefroy, O., & Stuss, D. T. (2007) · Cambridge University Press eBooks · doi:10.1017/cbo9780511544880.020 · Cited by 29 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease
Petzinger, G. M., Fisher, B. E., McEwen, S., Beeler, J. A., Walsh, J. P., & Jakowec, M. W. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70123-6 · Cited by 798 · see citing works
Executive dysfunction in <scp>P</scp> arkinson's disease: A review
Dirnberger, G., & Jahanshahi, M. (2013) · Journal of Neuropsychology · doi:10.1111/jnp.12028 · Cited by 486 · see citing works
Godefroy, O., Fickl, A., Roussel, M., Auribault, C., Bugnicourt, J. M., Lamy, C., Canaple, S., & Petitnicolas, G. (2011) · Stroke · doi:10.1161/strokeaha.110.606277 · Cited by 303 · see citing works
Self-citationBayot, M., Dujardin, K., Tard, C., Defebvre, L., Bonnet, C. T., Allart, E., & Delval, A. (2018) · Neurophysiologie Clinique · doi:10.1016/j.neucli.2018.10.003 · Cited by 289 · see citing works
Executive Functioning in Schizophrenia
Orellana, G., & Slachevsky, A. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00035 · Cited by 283 · see citing works
Phenotypic spectrum of probable and genetically-confirmed idiopathic basal ganglia calcification
Nicolas, G., Pottier, C. P., Charbonnier, C., Guyant‐Maréchal, L., Ber, I. L., Pariente, J., Labauge, P. M., Ayrignac, X., Defebvre, L., Maltête, D., et al. (2013) · Brain · doi:10.1093/brain/awt255 · Cited by 240 · see citing works
da Costa, A. L. C., Bagoj, E., Monaco, M., Zabberoni, S., Rosa, S. D., Papantonio, A. M., Mundi, C., Caltagirone, C., & Carlesimo, G. A. (2013) · Neurological Sciences · doi:10.1007/s10072-013-1520-8 · Cited by 172 · see citing works
Bouc, R. L., Lenfant, P., Delbeuck, X., Ravasi, L., Lebert, F., Semah, F., & Pasquier, F. (2012) · Brain · doi:10.1093/brain/aws237 · Cited by 138 · see citing works
Louapre, C., Perlbarg, V., García-Lorenzo, D., Urbanski, M., Benali, H., Assouad, R., Damien Galanaud, E., Freeman, L. A., Bodini, B., Papeix, C., et al. (2014) · Human Brain Mapping · doi:10.1002/hbm.22505 · Cited by 134 · see citing works
Dopaminergic modulation of motor network dynamics in Parkinson's disease
Michely, J., Volz, L. J., Barbe, M. T., Hoffstaedter, F., Viswanathan, S., Timmermann, L., Eickhoff, S. B., Fink, G. R., & Grefkes, C. (2015) · Brain · doi:10.1093/brain/awu381 · Cited by 124 · see citing works
Plantier, D., & Luauté, J. (2016) · Annals of Physical and Rehabilitation Medicine · doi:10.1016/j.rehab.2015.10.003 · Cited by 112 · see citing works
Mild cognitive impairment and cognitive reserve in Parkinson’s disease
Poletti, M., Emre, M., & Bonuccelli, U. (2011) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2011.03.013 · Cited by 102 · see citing works
Narme, P., Mouras, H., Roussel, M., Duru, C., Krystkowiak, P. C., & Godefroy, O. (2013) · Neuropsychology · doi:10.1037/a0031522 · Cited by 104 · see citing works
Self-citationStefan, A., & Mathé, J.-F. (2016) · Annals of Physical and Rehabilitation Medicine · doi:10.1016/j.rehab.2015.11.002 · Cited by 102 · see citing works
Vallat‐Azouvi, C., Pradat-Diehl, P., & Azouvi, P. (2012) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2012.681110 · Cited by 95 · see citing works
Self-citationInitial Experience Using Awake Surgery for Glioma
Mandonnet, E., Hamer, P. C. D. W., Poisson, I., Whittle, I. R., Bernat, A.-L., Bresson, D., Madadaki, C., Bouazza, S., Ursu, R., Carpentier, A. F., et al. (2015) · Neurosurgery · doi:10.1227/neu.0000000000000644 · Cited by 91 · see citing works
Corbo, I., & Casagrande, M. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11051204 · Cited by 93 · see citing works
Available Virtual Reality-Based Tools for Executive Functions: A Systematic Review
Borgnis, F., Baglio, F., Pedroli, E., Rossetto, F., Uccellatore, L., Oliveira, J., Riva, G., & Cipresso, P. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.833136 · Cited by 89 · see citing works
Godefroy, O., Gibbons, L. E., Diouf, M., Nyenhuis, D. L., Roussel, M., Black, S. E., & Bugnicourt, J. M. (2014) · Cortex · doi:10.1016/j.cortex.2014.01.016 · Cited by 71 · see citing works
Self-citationMontalan, B., Lelard, T., Godefroy, O., & Mouras, H. (2012) · Frontiers in Psychology · doi:10.3389/fpsyg.2012.00389 · Cited by 68 · see citing works
Self-citationDissociation between verbal response initiation and suppression after prefrontal lesions.
Volle, E., Costello, A. D. L., Coates, L. M., McGuire, C., Towgood, K., Gilbert, S., Kinkingnéhun, S., McNeil, J., Greenwood, R., Papps, B., et al. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhr322 · Cited by 64 · see citing works
Marras, C., Tröster, A. I., Kulisevsky, J., & Stebbins, G. T. (2014) · Movement Disorders · doi:10.1002/mds.25874 · Cited by 66 · see citing works
Nonmotor Symptoms in Parkinson Disease: A Descriptive Review on Social Cognition Ability
Palmeri, R., Buono, V. L., Corallo, F., Foti, M., Lorenzo, G. D., Bramanti, P., & Marino, S. (2017) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988716687872 · Cited by 66 · see citing works
Dulau, C., Deloire, M., Diaz, H., Saubusse, A., Charré‐Morin, J., Prouteau, A., & Brochet, B. (2017) · Journal of Neurology · doi:10.1007/s00415-017-8417-z · Cited by 66 · see citing works
Kocka, A., & Gagnon, J. (2014) · Behavioral Sciences · doi:10.3390/bs4040352 · Cited by 65 · see citing works
Vallet, G. T., Hudon, C., Bier, N., Macoir, J., Versace, R., & Simard, M. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01493 · Cited by 64 · see citing works
The Behavioral and Cognitive Executive Disorders of Stroke: The GREFEX Study
Roussel, M., Martinaud, O., Hénon, H., Vercelletto, M., Bindschaedler, C. R., Joseph, P., Robert, P. H., Labauge, P. M., Godefroy, O., & on behalf of the GREFEX study group (2016) · PLoS ONE · doi:10.1371/journal.pone.0147602 · Cited by 63 · see citing works
Self-citationA Qualitative Review of Instrumental Activities of Daily Living in Dementia: what’s cooking?
Sikkes, S. A. M., & de Rotrou, J. (2014) · Neurodegenerative Disease Management · doi:10.2217/nmt.14.24 · Cited by 63 · see citing works
Autism spectrum disorder associated with 49,XYYYY: case report and review of the literature
Demily, C., Poisson, A., Peyroux, É., Gatellier, V., Nicolas, A., Rigard, C., Schluth‐Bolard, C., Sanlaville, D., & Rossi, M. (2017) · BMC Medical Genetics · doi:10.1186/s12881-017-0371-1 · Cited by 62 · see citing works
Executive functions in clinical and preclinical Alzheimer's disease
Allain, P., Etcharry‐Bouyx, F., & Verny, C. (2013) · Revue Neurologique · doi:10.1016/j.neurol.2013.07.020 · Cited by 61 · see citing works
Cognitive and behavioral disorders in Parkinson’s disease: an update. II: behavioral disorders
Trojano, L., & Papagno, C. (2017) · Neurological Sciences · doi:10.1007/s10072-017-3155-7 · Cited by 61 · see citing works
Changes in weight after traumatic brain injury in adult patients: A longitudinal study
Crenn, P. P., Hamchaoui, S., Massari, A., Hanachi, M., Melchior, J., & Azouvi, P. (2013) · Clinical Nutrition · doi:10.1016/j.clnu.2013.06.003 · Cited by 60 · see citing works
Self-citationCognitive impairment after cerebral venous thrombosis: a two-center study
Bugnicourt, J., Guegan-Massardier, E., Roussel, M., Martinaud, O., Canaple, S., Triquenot-Bagan, A., Wallon, D., Lamy, C., Leclercq, C., Hannequin, D., et al. (2012) · Journal of Neurology · doi:10.1007/s00415-012-6799-5 · Cited by 62 · see citing works
Self-citationPlasticity in striatopallidal projection neurons mediates the acquisition of habitual actions
Shan, Q., Christie, M. J., & Balleine, B. W. (2015) · European Journal of Neuroscience · doi:10.1111/ejn.12971 · Cited by 57 · see citing works
Demyelination in Mild Cognitive Impairment Suggests Progression Path to Alzheimer’s Disease
Carmeli, C., Donati, A., Antille, V., Viceic, D., Ghika, J. A., von Gunten, A., Clarke, S., Meuli, R. A., Frackowiak, R. S. J., & Knyazeva, M. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072759 · Cited by 57 · see citing works
Dysexecutive disorders and their diagnosis: A position paper
Godefroy, O., Martinaud, O., Narme, P., Joseph, P., Mosca, C., Lhommée, E., Meulemans, T., Czernecki, V., Bertola, C., Labauge, P. M., et al. (2018) · Cortex · doi:10.1016/j.cortex.2018.09.026 · Cited by 58 · see citing works
Self-citationPhenotypic variability of PINK1 expression: 12 Years' clinical follow‐up of two Italian families
Ricciardi, L., Petrucci, S., Guidubaldi, A., Ialongo, T., Serra, L., Ferraris, A., Spanò, B., Bozzali, M., Valente, E. M., & Bentivoglio, A. R. (2014) · Movement Disorders · doi:10.1002/mds.25994 · Cited by 57 · see citing works
Narme, P., Mouras, H., Roussel, M., Devendeville, A., & Godefroy, O. (2013) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2013.823911 · Cited by 55 · see citing works
Self-citationIntraoperative Monitoring of an Aspect of Executive Functions
Wager, M., Boisguéheneuc, F. D., Pluchon, C., Bouyer, C., Stal, V., Bataille, B., Guillevin, C., & Gil, R. (2012) · Operative Neurosurgery · doi:10.1227/neu.0b013e31827bf1d6 · Cited by 55 · see citing works
PDGFB Partial Deletion: a New, Rare Mechanism Causing Brain Calcification with Leukoencephalopathy
Nicolas, G., Rovelet‐Lecrux, A., Pottier, C. P., Martinaud, O., Wallon, D., Vernier, L., Landemore, G., Chapon, F., Prieto-Morin, C., Tournier‐Lasserve, E., et al. (2014) · Journal of Molecular Neuroscience · doi:10.1007/s12031-014-0265-z · Cited by 55 · see citing works
Ihnen, J., Antivilo-Bruna, A., Muñoz‐Neira, C., & Slachevsky, A. (2013) · Dementia & Neuropsychologia · doi:10.1590/s1980-57642013dn70100007 · Cited by 54 · see citing works
Merck, C., Charnallet, A., Auriacombe, S., Belliard, S., Hahn‐Barma, V., Kremin, H., Lemesle, B., Mahieux, F., Moreaud, O., Perrier, D., et al. (2011) · Revue de neuropsychologie · doi:10.3917/rne.034.0235 · Cited by 49 · see citing works
Self-citationIncreased activation in Broca's area after cognitive remediation in schizophrenia
Vianin, P., Urben, S., Magistretti, P. J., Marquet, P. P., Fornari, E., & Jaugey, L. (2014) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2014.01.004 · Cited by 49 · see citing works
Prevalence and profile of cognitive impairment in adult glioma: a sensitivity analysis
Boone, M., Roussel, M., Chauffert, B., Gars, D. L., & Godefroy, O. (2016) · Journal of Neuro-Oncology · doi:10.1007/s11060-016-2152-7 · Cited by 49 · see citing works
Self-citationPeltier, J., Roussel, M., Gerard, Y., Lassonde, M. C., Deramond, H., Gars, D. L., Beaumont, L. D., & Godefroy, O. (2012) · Journal of Neurology · doi:10.1007/s00415-012-6421-x · Cited by 48 · see citing works
Self-citationPasseri, E., Villa, C., Couette, M., Itti, E., Brugières, P., Césaro, P., Gherardi, R. K., Bachoud‐Lévi, A., & Authier, F. (2011) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2011.08.006 · Cited by 48 · see citing works
Mandonnet, E., Cerliani, L., Siuda-Krzywicka, K., Poisson, I., Zhi, N., Emmanuelle Volle, C., & de Schotten, M. T. (2017) · Neurochirurgie · doi:10.1016/j.neuchi.2017.03.003 · Cited by 47 · see citing works
Godefroy, O., Leclercq, C., Roussel, M., Moroni, C., Quaglino, V., Beaunieux, H., Tallia, H., Nédélec-Ciceri, C., Bonnin, C. A., Thomas-Antérion, C., et al. (2012) · International Journal of Stroke · doi:10.1111/j.1747-4949.2012.00794.x · Cited by 47 · see citing works
Self-citationThe impact of inhibition capacities and age on number–space associations
Hoffmann, D., Pigat, D., & Schiltz, C. (2014) · Cognitive Processing · doi:10.1007/s10339-014-0601-9 · Cited by 46 · see citing works
Bertoux, M., O’Callaghan, C., Dubois, B., & Hornberger, M. (2015) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2015-311643 · Cited by 47 · see citing works
Alteration profile of executive functions in multiple sclerosis
García, M. C., Plasencia, P. M., & Aladro, Y. (2015) · Acta Neurologica Scandinavica · doi:10.1111/ane.12345 · Cited by 46 · see citing works
Roussel, M., Dujardin, K., Hénon, H., & Godefroy, O. (2012) · Brain · doi:10.1093/brain/aws132 · Cited by 45 · see citing works
Self-citationMandonnet, E. (2019) · World Neurosurgery · doi:10.1016/j.wneu.2019.08.071 · Cited by 45 · see citing works
The Epidemiology and Clinical Manifestations of Dysexecutive Syndrome in Parkinson’s Disease
Ceravolo, R., Pagni, C., Tognoni, G., & Bonuccelli, U. (2012) · Frontiers in Neurology · doi:10.3389/fneur.2012.00159 · Cited by 45 · see citing works
Kiosses, D. N., Gross, J. J., Banerjee, S., Duberstein, P. R., Putrino, D. F., & Alexopoulos, G. S. (2017) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2017.01.011 · Cited by 46 · see citing works
Zhou, Z., Yan, Y., Gu, H., Sun, R., Liao, Z., Xue, K., & Tang, C. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.389631 · Cited by 44 · see citing works
Executive Functions Deficits After Severe Traumatic Brain Injury
Azouvi, P., Vallat‐Azouvi, C., Joseph, P., Meulemans, T., Bertola, C., Gall, D. L., Bellmann, A., Roussel, M., Coyette, F., Krier, M., et al. (2015) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0000000000000169 · Cited by 45 · see citing works
Self-citationCognitive Impairments and Dysexecutive Behavioral Disorders in Chronic Kidney Disease
Puy, L., Bugnicourt, J., Liabeuf, S., Desjardins, L., Roussel, M., Diouf, M., Chillon, J., Choukroun, G. J., Massy, Z. A., & Godefroy, O. (2018) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.18030047 · Cited by 44 · see citing works
Self-citationIs Reaction Time Slowing an Early Sign of Alzheimer’s Disease? A Meta-Analysis
Andriuta, D., Diouf, M., Roussel, M., & Godefroy, O. (2019) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000500348 · Cited by 44 · see citing works
Self-citationGonthier, C., Longuépée, L., & Bouvard, M. A. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2850-1 · Cited by 43 · see citing works
Course and etiology of dysexecutive MCI in a community sample
Huey, E. D., Manly, J. J., Tang, M., Schupf, N., Brickman, A. M., Manoochehri, M., Mez, J. B., DeCarli, C. S., Devanand, D. P., & Mayeux, R. P. (2013) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2012.10.014 · Cited by 45 · see citing works
Ecological validity of the Dysexecutive Questionnaire: Results from the PariS-TBI study
Azouvi, P., Vallat‐Azouvi, C., Millox, V., Darnoux, E., Ghout, I., Azerad, S., Ruet, A., Bayen, É., Pradat-Diehl, P., Aegerter, P., et al. (2014) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2014.990907 · Cited by 42 · see citing works
Self-citationMandonnet, E., Vincent, M., Valero‐Cabré, A., Facque, V., Barberis, M., Bonnetblanc, F., Rheault, F., Emmanuelle Volle, C., Descoteaux, M., & Margulies, D. S. (2020) · Cortex · doi:10.1016/j.cortex.2020.08.021 · Cited by 42 · see citing works
Schumacher, L. V., Schmidt, C. S. M., Egger, K. E., Amtage, F., Peter, J., Klöppel, S., Beume, L.-A., Hoeren, M., Weiller, C., & Kaller, C. P. (2015) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2015.07.017 · Cited by 42 · see citing works
Longitudinal changes of cortical morphology in CADASIL
Jouvent, É., Mangin, J., Duchesnay, É., Porcher, R., Duering, M., Mewald, Y., Guichard, J., Hervé, D., Reyes, S., Zieren, N., et al. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.09.013 · Cited by 40 · see citing works
Grossi, D., Santangelo, G., Barbarulo, A. M., Vitale, C., Castaldo, G., Proto, M. G., Siano, P., Barone, P., & Trojano, L. (2013) · Behavioural Neurology · doi:10.1155/2013/781029 · Cited by 39 · see citing works
Murray, L. L. (2016) · Aphasiology · doi:10.1080/02687038.2016.1261248 · Cited by 39 · see citing works
Vascular cognitive impairment: Advances and trends
Barbay, M., Taillia, H., Nédélec-Ciceri, C., Arnoux, A., Puy, L., Wiener, E., Canaple, S., Lamy, C., Godefroy, O., & Roussel, M. (2017) · Revue Neurologique · doi:10.1016/j.neurol.2017.06.009 · Cited by 39 · see citing works
Self-citationde Rotrou, J., Wu, Y.-H., Hugonot-Diener, L., Thomas-Antérion, C., Vidal, J., Plichart, M., Rigaud, A., & Hanon, O. (2012) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000338232 · Cited by 36 · see citing works
Salas, C. E., Radovic, D., Yuen, K. S. L., Yeates, G., Castro, O., & Turnbull, O. H. (2014) · Bulletin of the Menninger Clinic · doi:10.1521/bumc.2014.78.4.301 · Cited by 35 · see citing works
Andriuta, D., Si-Ahmed, C., Roussel, M., Constans, J., Makki, M., Aarabi, A., Basille, D., Andréjak, C., & Godefroy, O. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-215506 · Cited by 35 · see citing works
Self-citationThe Evolution of Personality in Patients with Mild Cognitive Impairment
Donati, A., Studer, J., Petrillo, S. M., Pocnet, C., Popp, J., Rossier, J., & von Gunten, A. (2013) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000353895 · Cited by 34 · see citing works
Identifying bvFTD within the wide spectrum of late onset frontal lobe syndrome: a clinical approach
Krudop, W. A., Kerssens, C. J., Dols, A., Prins, N. D., Möller, C., Schouws, S., van der Flier, W. M., Scheltens, P., Sikkes, S., Stek, M. L., et al. (2015) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2015.04.002 · Cited by 33 · see citing works
Dysexecutive syndrome in amnesic mild cognitive impairment: a multicenter study
Martín, E. B., Serrano, I. U., Martín, X. E., Alcelay, L. G., Salazar, A. M., Gandarias, R. B., Borda, S. I., Valiente, J., Juanbeltz, M. B. I., López, J. M., et al. (2016) · BMC Neurology · doi:10.1186/s12883-016-0607-2 · Cited by 32 · see citing works
Traumatic Brain Injury and Suicidal Behavior: A Review
Wadhawan, A., Stiller, J. W., Potocki, E., Okusaga, O. O., Dagdag, A., Lowry, C. A., Benros, M. E., & Postolache, T. T. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-181055 · Cited by 32 · see citing works
Juan, E., Marzia De Lucia, E., Beaud, V., Oddo, M., Rusca, M., Viceic, D., Clarke, S., & Rossetti, A. O. (2018) · Critical Care Medicine · doi:10.1097/ccm.0000000000002946 · Cited by 31 · see citing works
Douven, E., Köhler, S., Schievink, S. H. J., van Oostenbrugge, R. J., Staals, J., Verhey, F. R. J., & Aalten, P. (2017) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2017.09.022 · Cited by 31 · see citing works
Comparison of Neuropsychological Assessment by Videoconference and Face to Face
Gnassounou, R., Defontaines, B., Denolle, S., Brun, S. D. L., Germain, R., Schwartz, D., Schück, S., Michon, A., Belin, C., & Maillet, D. (2021) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617721000679 · Cited by 30 · see citing works
Vlagsma, T. T., Koerts, J., Fasotti, L., Tucha, O. M., van Laar, T., Dijkstra, H. T., & Spikman, J. M. (2015) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2015.1013138 · Cited by 30 · see citing works
Association Between Traumatic Brain Injury-Related Brain Lesions and Long-term Caregiver Burden
Guevara, A. B., Démonet, J., Polejaeva, E., Knutson, K. M., Wassermann, E. M., Grafman, J. H., & Krüeger, F. (2015) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0000000000000151 · Cited by 29 · see citing works
Frontal Assessment Battery in Parkinson’s Disease: Validity and Morphological Correlates
Bezdíček, O., Růžička, F., Mazancová, A. F., Roth, J., Dušek, P., Mueller, K., Růžička, E., & Jech, R. (2017) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617717000522 · Cited by 29 · see citing works
Personality and behavioral changes after brain tumor resection: a lesion mapping study
Lemaitre, A., Herbet, G., Duffau, H., & Lafargue, G. (2021) · Acta Neurochirurgica · doi:10.1007/s00701-021-04756-9 · Cited by 27 · see citing works
Granziera, C., Daducci, A., Donati, A., Bonnier, G., Romascano, D., Roche, A., Cuadra, M. B., Schmitter, D., Klöppel, S., Meuli, R. A., et al. (2015) · NeuroImage Clinical · doi:10.1016/j.nicl.2015.06.003 · Cited by 28 · see citing works
Impact of pain on cognitive functions in primary Sjögren syndrome with small fiber neuropathy
Indart, S., Hugon, J., Guillausseau, P. J., Gilbert, A., Dumurgier, J., Paquet, C., & Sène, D. (2017) · Medicine · doi:10.1097/md.0000000000006384 · Cited by 28 · see citing works
Kasai, M., Meguro, K., Nakamura, K., Nakatsuka, M., Ouchi, Y., & Tanaka, N. (2012) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000340047 · Cited by 27 · see citing works
Narme, P., Roussel, M., Mouras, H., Krystkowiak, P. C., & Godefroy, O. (2016) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2016.1171291 · Cited by 26 · see citing works
Self-citationMartínez‐Pernía, D., Núñez-Huasaf, J., del Blanco, Á., Ruiz‐Tagle, A., Velásquez, J. D., Gomez, M. A. A., Blesius, C. R., Ibáñez, A. M., Fernández‐Manjón, B., & Slachevsky, A. (2017) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2017.08.012 · Cited by 26 · see citing works
The clinical and anatomical heterogeneity of environmental dependency phenomena
Lagarde, J., Valabrègue, R., Corvol, J., Ber, I. L., Colliot, O., Vidailhet, M., & Lévy, R. (2013) · Journal of Neurology · doi:10.1007/s00415-013-6976-1 · Cited by 21 · see citing works
Role of Executive Dysfunction and Dysexecutive Behavior in Late-Life Depression and Disability
Gansler, D. A., Suvak, M., Arean, P., & Alexopoulos, G. S. (2015) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2015.05.003 · Cited by 24 · see citing works
Daulatzai, M. A. (2016) · Neurotoxicity Research · doi:10.1007/s12640-016-9643-3 · Cited by 25 · see citing works
Wang, X., Wu, J., Zhang, H., & Zheng, G. (2023) · Clinical Rehabilitation · doi:10.1177/02692155231215891 · Cited by 23 · see citing works
Ratovohery, S., Baudouin, A., Palisson, J., Maillet, D., Bailon, O., Belin, C., & Narme, P. (2019) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2019.1650897 · Cited by 24 · see citing works
Network-level prediction of set-shifting deterioration after lower-grade glioma resection
Mrah, S., Descoteaux, M., Wager, M., Boré, A., Rheault, F., Thirion, B., & Mandonnet, E. (2022) · Journal of neurosurgery · doi:10.3171/2022.1.jns212257 · Cited by 23 · see citing works
The role of exercise in Parkinson’s Disease
Almikhlafi, M. A. (2023) · Neurosciences · doi:10.17712/nsj.2023.1.20220105 · Cited by 22 · see citing works
Martínez‐Pernía, D., Olavarría, L., Fernández‐Manjón, B., Cabello, V., Henríquez, F., Robert, P. H., Alvarado, L., Barría, S., Antivilo-Bruna, A., Velásquez, J. D., et al. (2023) · Applied Neuropsychology Adult · doi:10.1080/23279095.2023.2174438 · Cited by 22 · see citing works
Self-citationSelf-Generated Strategic Behavior in an Ecological Shopping Task
Bottari, C. L., Shun, P. L. W., Dorze, G. L., Gosselin, N., & DAWSON, D. R. (2013) · American Journal of Occupational Therapy · doi:10.5014/ajot.2014.008987 · Cited by 22 · see citing works
Episodic Memory Impairment Mediates the Loss of Awareness in Mild Cognitive Impairment
Gagliardi, G. P., & Vannini, P. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.802501 · Cited by 21 · see citing works
Determinants of disability at 6 months after stroke: The GRECogVASC Study
Tasseel‐Ponche, S., Barbay, M., Roussel, M., Lamrani, A., Sader, T., Arnoux, A., Canaple, S., Lamy, C., Leclercq, C., Aarabi, A., et al. (2022) · European Journal of Neurology · doi:10.1111/ene.15319 · Cited by 21 · see citing works
Self-citationAssessing the dysexecutive syndrome in dementia
Gansler, D. A., Huey, E. D., Pan, J. J., Wasserman, E. M., & Grafman, J. H. (2016) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2016-313576 · Cited by 21 · see citing works
Andriuta, D., Roussel, M., Barbay, M., Wannepain, S., Godefroy, O., Godefroy and GRECogVASC study group, Godefroy, O., Roussel, M., Barbay, M., Canaple, S., et al. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-171097 · Cited by 21 · see citing works
Self-citation
- Authors
- Godefroy, O., Azouvi, P., Robert, P., Roussel, M., LeGall, D., Meulemans, T., & Behalf of the Groupe de Réflexion sur l'Evaluation des Fonctions Exécutives Study Group
- Affiliations
- Centre Hospitalier Universitaire Amiens-Picardie (FR)
- Hôpital Raymond-Poincaré (FR)
- Centre Hospitalier Universitaire de Nice (FR)
- Université d'Angers (FR)
- University of Liège (BE)
- Corresponding author
- Godefroy, Olivier
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 2010-12
- Volume
- 68
- Issue
- 6
- Pages
- 855-864
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2098389807
- Cited by
- 293
- References
- 44
- Citations by year
- 2026: 5 · 2025: 14 · 2024: 16 · 2023: 21 · 2022: 17 · 2021: 20 · 2020: 14 · 2019: 19 · 2018: 19 · 2017: 28 · 2016: 24 · 2015: 23 · 2014: 19 · 2013: 29 · 2012: 17
- FWCI
- 18.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- dysexecutive syndrome, executive dysfunction, diagnostic criteria, loss of autonomy, traumatic brain injury, stroke, mild cognitive impairment, Alzheimer's disease, multiple sclerosis, Parkinson's disease, cognitive assessment
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Cognition Disorders, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Personality Disorders, Personal Autonomy, Young Adult, Executive Function
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review