The DOI matches its Crossref record; 67 of the 68 references it cites were found in a registry or an index.
An introduction to the free radical hypothesis in Parkinson's disease
Abstract
Iron-induced oxidant stress has been implicated in the pathogenesis of Parkinson's disease. An increasing body of evidence now indicates that in Parkinson's disease the environment within the substantia nigra is conducive to the formation of cytotoxic free radicals and cell degeneration. Dopamine neurons may be particularly vulnerable because of the oxidative metabolism of dopamine and the potential of neuromelanin to promote the site-specific accumulation and reduction of iron. This hypothesis has attracted considerable attention because it opens the way for employing antioxidant strategies as possible neuroprotective treatment for Parkinson's disease. Although the concept is appealing, free radicals have not yet been proven to play a role in Parkinson's disease, and many important issues remain to be resolved before the oxidative hypothesis can ultimately be confirmed or refuted.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“This observation is in agreement with a similar analysis that was performed on autopsy specimens ([51](#R51)).”
From Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease (1997) · cites this paper as [51]
Citations
Cites
McCord, J. M., & Fridovich, I. (1969) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63504-5 · Cited by 12,952
Oxygen toxicity, oxygen radicals, transition metals and disease
Halliwell, B., & Gutteridge, J. M. C. (1984) · Biochemical Journal · doi:10.1042/bj2190001 · Cited by 5,330
Mitochondrial DNA and human evolution
Cann, R. L., Stoneking, M., & Wilson, A. C. (1987) · Nature · doi:10.1038/325031a0 · Cited by 3,100
Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts
Halliwell, B., & Gutteridge, J. M. C. (1986) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(86)90305-x · Cited by 2,038
DNA damage and oxygen radical toxicity
Imlay, J. A., & Linn, S. (1988) · Science · doi:10.1126/science.3287616 · Cited by 1,974
Oxygen radicals and human disease
CROSS, C. E., HALLIWELL, B., BORISH, E. T., PRYOR, W. A., AMES, B. N., SAUL, R. L., McCORD, J. M., & HARMAN, D. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-107-4-526 · Cited by 1,856
MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE
Schapira, A. H. V., Cooper, J. A. D., Dexter, D. T., Jenner, P. G., Clark, J. B., & MARSDEN, C. D. (1989) · The Lancet · doi:10.1016/s0140-6736(89)92366-0 · Cited by 1,757
The effect of age on the non-haemin iron in the human brain
Hallgren, B., & Sourander, P. (1958) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1958.tb12607.x · Cited by 1,427
Basal Lipid Peroxidation in Substantia Nigra Is Increased in Parkinson's Disease
Dexter, D. T., Carter, C. J., Wells, F. R., Javoy-Agid, F., Agid, Y., Lees, A. J., Jenner, P. G., & MARSDEN, C. D. (1989) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1989.tb09133.x · Cited by 1,397
Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains
Riederer, P., Sofic, E., Rausch, W., Schmidt, B., Reynolds, G. P., Jellinger, K., & Youdim, M. B. H. (1989) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1989.tb09150.x · Cited by 1,383
Research works printed but not linked: 14
- Halliwell, 1985, TINS, 8, 22
- Cohen, 1990, Neural Transm, 32, 229
- Olanow, 1990, Neurology, 40, 32
- Halliwell, 1988, ISI Atlas Sci Biochem, 1, 48
- Potts, 1976, Exp Eye Res, 48, 221
- Sarna, 1976, Science, 1132, 192
- Brain iron: MRI studies in Parkinson's syndrome. In: eds. Florham Park, New Jersey: MacMillan Healthcare, 1987: 135-143
- Sengstock, 1991, Movement Dis, 6, 272
- Olanow, 1991, Neurology, 42, 13
- Riederer, 1989, J Neurochem, 52, 515, 10.1111/j.1471-4159.1989.tb09150.x · DOI · Paper page
- Good, 1992, J Neuropathol Exp Neurol, 51, 327
- et al. Vitamin E levels in brain are not altered in Parkinson's disease. Ann Neurol 1992 (in press)
- et al. Brain skeletal muscle and platelet mitochondrial function in Parkinson's disease. Brain 1992 (in press)
- Spina, 1988, J Pharmacol Exp Ther, 247, 502
Cited by
Sorted by citations
Items 201–300 of 381
NF-?B modulates lipopolysaccharide-induced microglial nerve growth factor expression
Heese, K., Fiebich, B. L., Bauer, J., & Otten, U. (1998) · Glia · doi:10.1002/(sici)1098-1136(199804)22:4 · Cited by 96
Zhang, J., Cazers, A. R., Lutzke, B. S., & Hall, E. D. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)e0090-6 · Cited by 32
Neurologic disease among women with breast implants
Winther, J. F., Bach, F. W., Friis, S., Blot, W. J., Mellemkjær, L., Kjøller, K., Høgsted, C., McLaughlin, J. K., & Olsen, J. H. (1998) · Neurology · doi:10.1212/wnl.50.4.951 · Cited by 31
Maurice, T., Roman, F. J., & Privat, A. (1996) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19961215)46:6 · Cited by 100
Barkats, M., Nakao, N., Grasbon-Frodl, E. M., Bilang‐Bleuel, A., Revah, F., Mallet, J. J., & Brundin, P. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00526-x · Cited by 31
Neuroprotective Therapy for Parkinson's Disease
Koller, W. C. (1997) · Experimental Neurology · doi:10.1006/exnr.1996.6383 · Cited by 30
Expression of Superoxide Dismutase Following Axotomy
Rosenfeld, J., Cook, S., & James, R. (1997) · Experimental Neurology · doi:10.1006/exnr.1997.6604 · Cited by 30
Growing old: the most common mitochondrial disease of all?
Harding, A. E. (1992) · Nature Genetics · doi:10.1038/ng1292-251 · Cited by 29
Langeveld, C. H., Schepens, E., Stoof, J. C., Bast, A., & Drukarch, B. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(95)00014-o · Cited by 29
Muscarinic receptor subtype determines vulnerability to oxidative stress in COS-7 cells
Joseph, J. A., Fisher, D. R., & Strain, J. G. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00779-1 · Cited by 29
Konings, C. H., Kuiper, M. A., Teerlink, T., Mulder, C., Scheltens, P., & Wolters, E. C. (1999) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(99)00167-7 · Cited by 28
Zhang, J., Andrus, P. K., & Hall, E. D. (1994) · Brain Research · doi:10.1016/0006-8993(94)91741-8 · Cited by 28
Joseph, J. A., Cao, G., & Cutler, R. (1995) · Brain Research · doi:10.1016/0006-8993(94)01320-h · Cited by 28
Noschang, C. G., Krolow, R., Fontella, F. U., Arcego, D. M., Diehl, L. A., Weis, S. N., Arteni, N. S., & Dalmaz, C. (2010) · Neurochemical Research · doi:10.1007/s11064-010-0158-7 · Cited by 27
Experience with tranylcypromine in early Parkinson’s disease
Fahn, S., & Chouinard, S. (1998) · Journal of neural transmission. Supplementum · doi:10.1007/978-3-7091-6499-0_6 · Cited by 27
Neuronal protective and rescue effects of deprenyl against MPP+ dopaminergic toxicity
Wu, R., Murphy, D. L., & Chiueh, C. C. (1995) · Journal of Neural Transmission · doi:10.1007/bf01276865 · Cited by 27
Siddique, Y. H., Faisal, M., Naz, F., Jyoti, S., & Rahul, R. (2014) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(14)60118-7 · Cited by 26
da-Rosa, D. D., Valvassori, S. S., Steckert, A. V., Arent, C. O., Ferreira, C. L., Lopes-Borges, J., Varela, R. B., Mariot, E., Dal‐Pizzol, F., Andersen, M. L., et al. (2011) · Journal of Neural Transmission · doi:10.1007/s00702-011-0691-9 · Cited by 26
Vitamin A and E levels are normal in amyotrophic lateral sclerosis
Iwasaki, Y., Ikeda, K., & Kinoshita, M. (1995) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(95)00145-r · Cited by 26
Psychomotor Effects of Dopamine Infusion Under Decreased Glutathione Conditions
Shukitt‐Hale, B., Denisova, N. A., Strain, J. G., & Joseph, J. A. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(97)00094-4 · Cited by 26
The Role of Iron in Parkinson Disease and 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Toxicity
Yantiri, F., & Andersen, J. K. (1999) · IUBMB Life · doi:10.1080/713803493 · Cited by 25
Zhao, M., Li, Z., Wu, Y., Tang, Y., Wang, C., Zhang, Z., & Peng, S. (2007) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2006.12.027 · Cited by 25
TOPA quinone, a kainate-like agonist and excitotoxin is generated by a catecholaminergic cell line
Newcomer, T. A., Rosenberg, P. A., & Aizenman, E. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-04-03172.1995 · Cited by 25
Ellmore, T. M., Suescun, J., Castriotta, R. J., & Schiess, M. C. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.00815 · Cited by 24
Noschang, C. G., Krolow, R., Arcego, D. M., Toniazzo, A. P., Huffell, A. P., & Dalmaz, C. (2012) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2012.01.010 · Cited by 24
Antinociceptive Effects of Intraperitoneal and Intrathecal Vitamin E in the Rat Formalin Test
Kim, M. J., Hong, B., Zhang, E. J., Ko, Y., & Lee, W. H. (2012) · The Korean journal of pain · doi:10.3344/kjp.2012.25.4.238 · Cited by 24
Ginseng berry aqueous extract prevents scopolamine‑induced memory impairment in mice
Hu, J., Chun, Y., Kim, J., Cho, I. J., & Ku, S. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.8090 · Cited by 24
Pioro, E. P. (2000) · Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders · doi:10.1080/14660820050515656 · Cited by 24
Chen, L., Cai, C., Yang, T., Lin, J., Cai, S., Zhang, J., & Chen, Z. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.12.033 · Cited by 24
Anti-stress Effects of Flavonoids from Buckwheat Sprouts in Mice Subjected to Restraint Stress
Watanabe, M., & Ayugase, J. (2008) · Food Science and Technology Research · doi:10.3136/fstr.14.253 · Cited by 23
Wengenack, T. M., Curran, G. L., Olson, E. E., & Poduslo, J. F. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00565-9 · Cited by 23
The Role of Oxidative Stress in Signal Transduction Changes and Cell Loss in Senescence
Joseph, J. A., & Cutler, R. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb21787.x · Cited by 23
Olanow, C. W. (1996) · Springer eBooks · doi:10.1007/978-3-7091-7494-4_7 · Cited by 23
Self-citationLiu, G., Men, P., Perry, G. L., & Smith, M. A. (2009) · Progress in brain research · doi:10.1016/s0079-6123(08)80005-2 · Cited by 22
Effect of reactive oxygen species on the metabolism of tryptophan in rat brain: Influence of age
Hussain, A. M., & Mitra, A. K. (2004) · Molecular and Cellular Biochemistry · doi:10.1023/b:mcbi.0000012849.16750.00 · Cited by 22
Leaf, C. D., & Pace, G. W. (1994) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.3.12.1293 · Cited by 22
Lee, C., Wu, D., Chen, S., Lin, Y., & Lee, T. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16816 · Cited by 21
Antioxidant systemic effect of short-term Cerebrolysin® administration
González, M. E., Turner, L. F., & Castellano, O. (1998) · Journal of neural transmission. Supplementum · doi:10.1007/978-3-7091-6467-9_29 · Cited by 20
Hu, C., Sung, S., Liu, H., & Chang, J. (1999) · European Neurology · doi:10.1159/000008008 · Cited by 20
The neuromythology of silicone breast implants
Rosenberg, N. L. (1996) · Neurology · doi:10.1212/wnl.46.2.308 · Cited by 20
Wakai, M., Mokuno, K., Hashizume, Y., & Kato, K. (1994) · Acta Neuropathologica · doi:10.1007/bf00294508 · Cited by 20
Maternal Depression Model: Long-Lasting Effects on the Mother Following Separation from Pups
Toigo, E. V. P., Diehl, L. A., Ferreira, A. G. K., Mackendanz, V., Krolow, R., Benitz, A. N. D., Noschang, C. G., Huffell, A. P., Silveira, P. P., Wyse, Â. T. D. S., et al. (2011) · Neurochemical Research · doi:10.1007/s11064-011-0590-3 · Cited by 19
Isoprenoid pathway and free radical generation and damage in neuropsychiatric disorders.
Ravikumar, A., Arun, P., Devi, K. V. D., Augustine, J., & Kurup, P. A. (2000) · PubMed · Cited by 19
Influence of exercise-induced oxidative stress on the central nervous system
Somani, S. M., & Husain, K. M. (2000) · Elsevier eBooks · doi:10.1016/b978-044482650-3/50026-2 · Cited by 19
Pentoxifylline attenuates iminodipropionitrile-induced behavioral abnormalities in rats
Kadasah, S., Mutairy, A. A., Siddiquei, M. M., Khan, H. A., Arif, I. A., Moutaery, K. A., & Tariq, M. (2009) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e32832ec5ea · Cited by 18
Yang, X., Wang, T., Guo, J.-L., Sun, M., Wong, M. W., & Huang, D. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b06689 · Cited by 16
Thong, P. S. P., Watt, F., Ponraj, D., Leong, S. K., He, Y., & Lee, T. K. Y. (1999) · Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms · doi:10.1016/s0168-583x(99)00390-0 · Cited by 18
Pérez, V., Romera, M., Lizcano, J. M., Marco, J. L., & Unzeta, M. (2003) · Journal of Pharmacy and Pharmacology · doi:10.1211/002235703765344649 · Cited by 18
Kopalli, S. R., Koppula, S., Shin, K. Y., Noh, S.-J., Jin, Q., Hwang, B. Y., & Suh, Y. (2012) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2012.07.032 · Cited by 18
Liu, Y., Zhang, Z., & Yang, X. (2011) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb.9000341 · Cited by 17
Neurobehavioural deficits following postnatal iron overload: I spontaneous motor activity
Fredriksson, A., Schröder, N., & Archer, T. (2003) · Neurotoxicity Research · doi:10.1007/bf03033373 · Cited by 17
The Generation of Free Radicals by Blood Platelets
Joseph, M. (1995) · Elsevier eBooks · doi:10.1016/b978-012390120-0/50013-7 · Cited by 17
Modulation of brain catecholamine absorbing proteins by dopaminergic agents
Modi, P. I., Kashyap, A., Nair, V. D., Ross, G. M., Fu, M., Savelli, J. E., Marcotte, E. R., Barlas, C., & Mishra, R. K. (1996) · European Journal of Pharmacology · doi:10.1016/0014-2999(95)00849-7 · Cited by 16
Lack of toxicity of human neuromelanin to rat brain dopaminergic neurons
Aimi, Y., & McGeer, P. L. (1996) · Parkinsonism & Related Disorders · doi:10.1016/1353-8020(96)00004-1 · Cited by 16
Wang, W., Huang, X., Zhang, Y., Deng, G., Liu, X., Fan, C., Xi, Y., Yu, J., & Ye, X. (2018) · RSC Advances · doi:10.1039/c8ra01906a · Cited by 15
Simultaneous editing of GABA and glutathione at 7T using semi‐LASER localization
Saleh, M. G., Mikkelsen, M. E., Oeltzschner, G., Chan, K. L., Berrington, A., Barker, P. B., & Edden, R. A. E. (2017) · Magnetic Resonance in Medicine · doi:10.1002/mrm.27044 · Cited by 15
Khan, H. A., Deeb, S. A., Moutaery, K. A., & Tariq, M. (2004) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2004.09.006 · Cited by 15
Lorenc-Koci, E., Antkiewicz-Michaluk, L., Wardas, J., Zapała, M., & Wierońska, J. (2004) · Brain Research · doi:10.1016/j.brainres.2004.02.044 · Cited by 15
Coffee and its Active Compounds are Neuroprotective
Kim, J., & Lee, K. W. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-409517-5.00046-2 · Cited by 14
The early treatment of Parkinson's disease: levodopa, dopamine agonists or both
Stern, M. B. (2000) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(00)00045-6 · Cited by 14
Ropinirole‐Induced Symptomatic Sinus Node Dysfunction
Szymanski, C., Boey, S., & Hermida, J. S. (2008) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2008.01141.x · Cited by 14
Development of an in vitro model for cysteine dioxygenase expression in the brain
Qusti, S. Y., Parsons, R. B., Abouglila, K. D. H., Waring, R. H., Williams, A. C., & Ramsden, D. B. (2000) · Cell Biology and Toxicology · doi:10.1023/a:1007634110983 · Cited by 14
Striatal Dopamine Dynamics Are Altered Following an Intranigral Infusion of Iron in Adult Rats
Lin, A. M. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(97)00398-5 · Cited by 14
Metman, L. V., Sethy, V. H., Roberts, J. R., Bravi, D., Hoff, J. I., Mouradian, M. M., & Chase, T. N. (1994) · Movement Disorders · doi:10.1002/mds.870090512 · Cited by 14
Willis, G. L., & Armstrong, S. M. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00013-7 · Cited by 14
Nappi, A. J., & Vass, E. (1994) · Journal of Liquid Chromatography · doi:10.1080/10826079408013369 · Cited by 13
Neurobehavioural deficits following postnatal iron overload: II instrumental learning performance
Archer, T., Schoröder, N., & Fredriksson, A. (2003) · Neurotoxicity Research · doi:10.1007/bf03033374 · Cited by 13
Rationale for dopamine agonist use as monotherapy in Parkinsonʼs disease
Schwarz, J. (2003) · Current Opinion in Neurology · doi:10.1097/00019052-200312001-00006 · Cited by 13
Increased dopamine turnover in the putamen after MPTP treatment in common marmosets
Nomoto, M., Iwata, S.-I., Kaseda, S., Fukuda, T., & Nakagawa, S. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00584-2 · Cited by 13
Marco‐Contelles, J. (2024) · Antioxidants · doi:10.3390/antiox13040440 · Cited by 12
Sathyanarayana, R., Poojary, B., Revanasiddappa, B. C., Kumar, H., & Merugumolu, V. K. (2020) · Journal of the Chinese Chemical Society · doi:10.1002/jccs.201900452 · Cited by 12
Lee, T., Lee, C.-C., Harn, H., Chiou, T., Chuang, M., Chen, C., Chuang, C., Lin, P., & Lin, S. (2021) · Journal of Molecular Medicine · doi:10.1007/s00109-021-02135-6 · Cited by 12
Bashkatova, V. G., Mathieu-Kia, A.-M., DURAND, C., & Penit-Soria, J. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04160.x · Cited by 12
Neurotoxicity of methamphetamine and methylenedioxymethamphetamine
Seiden, L. S., Lew, R., & Malberg, J. E. (2001) · Neurotoxicity Research · doi:10.1007/bf03033233 · Cited by 12
Smith, R. A., Balis, F. M., Ott, K. H., Elsberry, D. D., Sherman, M. R., & Saifer, M. G. P. (1995) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(95)00051-3 · Cited by 12
Extracellular ATP-Induced Apoptosis in PC12 Cells
Sun, A. Y., & Chen, Y. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4869-0_5 · Cited by 12
Arendash, G. W., Olanow, C. W., & Sengstock, G. J. (1993) · Key topics in brain research · doi:10.1007/978-3-7091-9322-8_8 · Cited by 12
Self-citationLiu, X., Kato, H., Araki, T., Itoyama, Y., Kato, K., & Kogure, K. (1994) · Neuroscience Letters · doi:10.1016/0304-3940(94)90159-7 · Cited by 12
Burke, R. E. (1999) · Humana Press eBooks · doi:10.1007/978-1-4612-1602-5_22 · Cited by 12
Krolow, R., Noschang, C. G., Arcego, D. M., Pettenuzzo, L. F., Weis, S. N., Marcolin, M. L., Huffell, A. P., Mota, C. S., & Dalmaz, C. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0915-x · Cited by 11
Reinholz, M. M., Haggard, J. J., Curran, G. L., & Poduslo, J. F. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7117 · Cited by 11
Hassan, W. N., Cantuti‐Castelvetri, I., Denisova, N. A., Yee, A. S., Joseph, J. A., & Paulson, K. E. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00744-x · Cited by 11
Ma, T. C., Mihm, M. J., Bauer, J. A., & Hoyt, K. R. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04735.x · Cited by 11
Further Evidences for Neuroprotective Effects of Melatonin
Franceschini, D., Skaper, S. D., Floreani, M., Borin, G., & Giusti, P. (1999) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-4709-9_27 · Cited by 11
Elevated cerebrospinal fluid levels of manganese superoxide dismutase in bacterial meningitis
Hirose, Y., Mokuno, K., Wakai, M., Takahashi, A., Hashizume, Y., Yanagi, T., & Kato, K. (1995) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(95)00040-9 · Cited by 11
Reactive Oxygen Involvement in Neurodegenerative Pathways
Hensley, K., Pye, Q. N., Tabatabaie, T., Stewart, C. A., & Floyd, R. A. (1998) · Humana Press eBooks · doi:10.1007/978-1-59259-473-3_10 · Cited by 11
Striatal Metabolism of Hexanal, a Lipid Peroxidation Product, in the Rat
Jaar, V., Ste‐Marie, L., & Montgomery, J. A. (1999) · Metabolic Brain Disease · doi:10.1023/a:1020701612639 · Cited by 10
Kashihara, K., Sakai, K., Marui, K., & Shohmori, T. (1998) · Life Sciences · doi:10.1016/s0024-3205(98)00275-6 · Cited by 10
Tacrine in Alzheimer's Disease
Cutler, N. R., & Sramek, J. J. (1993) · New England Journal of Medicine · doi:10.1056/nejm199303183281114 · Cited by 11
Fyffe, W. E., Kronz, J. D., Edmonds, P. A., & Donndelinger, T. M. (1999) · Cell and Tissue Research · doi:10.1007/s004410051241 · Cited by 9
Rieder, C. R. D. M., Williams, A. C., & Ramsden, D. B. (2004) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2004000700015 · Cited by 9
Hydrogen peroxide modulates K+ ion currents in cultured Aplysia sensory neurons
Chang, D., Lim, C., Lee, S., & Kaang, B. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02316-3 · Cited by 9
OXIDATIVE STRESS AND PARKINSON DISEASE
Nikolova, G. (2012) · Cited by 8
Wąsik, A., Romańska, I., Michaluk, J., & Antkiewicz‐Michaluk, L. (2012) · Pharmacological Reports · doi:10.1016/s1734-1140(12)70880-0 · Cited by 8
Metabolomics and mitochondrial dysfunction in Alzheimer’s disease
Kim, D., Gim, J., Yoon, D., Kim, S., & Kim, H. (2016) · Genes & Genomics · doi:10.1007/s13258-016-0494-3 · Cited by 8
Gille, G., Radad, K., Reichmann, H., & Rausch, W. (2005) · Journal of Neural Transmission · doi:10.1007/s00702-005-0369-2 · Cited by 8
Joseph, J. A. (1995) · Neurobiology of Aging · doi:10.1016/0197-4580(95)00073-n · Cited by 8
Do, E., Taira, E., Irie, Y., Gan, Y., Tanaka, H., Kuo, C., & Miki, N. (2003) · Molecular and Cellular Biochemistry · doi:10.1023/a:1024157515342 · Cited by 8
Thong, P. S. P., He, Y., Lee, T., & Watt, F. (1997) · Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms · doi:10.1016/s0168-583x(97)00239-5 · Cited by 8
Joseph, J., & Gibson, G. (2007) · Springer eBooks · doi:10.1007/978-0-387-30411-3_12 · Cited by 6
Metadata
- Authors
- Olanow, C. W.
- Affiliations
- University of South Florida (US)
- Corresponding author
- Olanow, C. W.
- ORCID
- Olanow, C. W.
- Venue
- Annals of Neurology
- Publisher
- Wiley
- Published
- 1992
- Volume
- 32
- Issue
- S1
- Pages
- S2-S9
- ISSN
- 0364-5134 (ISSN-L)
- 1531-8249
- OpenAlex
- W2156259977
- Cited by
- 382
- References
- 68
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2023: 1 · 2021: 5 · 2020: 3 · 2019: 3 · 2018: 5 · 2017: 6 · 2016: 7 · 2015: 2 · 2014: 6 · 2013: 5 · 2012: 13
- FWCI
- 3.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Life Sciences › Neuroscience › Neurology › Neurological diseases and metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nuclear Receptors and Signaling
- Keywords
- Parkinson's disease, oxidative stress, iron accumulation, substantia nigra, dopaminergic neurons, neuromelanin, dopamine oxidation, neuroprotection, antioxidants, neurodegeneration
- MeSH terms
- Animals, Free Radicals, Humans, Iron, Parkinson Disease, Substantia Nigra, Lipid Peroxidation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review