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Mitochondrial organization and structure are compromised in fibroblasts from patients with Huntington’s disease

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VGF and striatal cell damage in in vitro and in vivo models of Huntington's disease

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Sub-Chronic Copper Pretreatment Reduces Oxidative Damage in an Experimental Huntington’s Disease Model

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Reduced mitochondrial complex II activity enhances cell death via intracellular reactive oxygen species in STHdhQ111 striatal neurons with mutant huntingtin

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Time-Course Analysis of Protein and Lipid Oxidation in the Brains of Yac128 Huntington's Disease Transgenic Mice

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Geldanamycin attenuates 3-nitropropionic acid-induced apoptosis and JNK activation through the expression of HSP 70 in striatal cells

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The Drosophila Model: Exploring Novel Therapeutic Compounds against Neurodegenerative Diseases

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An abnormal striatal synaptic plasticity may account for the selective neuronal vulnerability in Huntington's disease

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Bypassing mitochondrial defects rescues Huntington's phenotypes in Drosophila

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Deficits of glutamate transmission in the striatum of toxic and genetic models of Huntington's disease

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Increased expression of transglutaminase 2 drives glycolytic metabolism in renal carcinoma cells

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Delayed Onset and Reduced Cognitive Deficits through Pre-Conditioning with 3-Nitropropionic Acid is Dependent on Sex and CAG Repeat Length in the R6/2 Mouse Model of Huntington’s Disease

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Role of Phosphorylated Tau and Glucose Synthase Kinase 3 Beta in Huntington’s Disease Progression

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Study of Oxidative Damage and Antioxidant Systems in Two Huntington’s Disease Rodent Models

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An Integrated Strategy for Evaluation of Metabolic and Oxidative Defects in Neurodegenerative Illness Using Magnetic Resonance Techniques

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DNA Damage and Chromatin Rearrangement Work Together to Promote Neurodegeneration

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Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics

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Mitochondrial Biology and the Identification of Biomarkers of Huntington’s Disease

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Impaired XK recycling for importing manganese underlies striatal vulnerability in Huntington's disease

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Huntington’s Disease-Like 2

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4‐hydroxy tempo improves mitochondrial and neurobehavioral deficits in experimental model of H untington's disease

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Challenges of Huntington's disease and quest for therapeutic biomarkers

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Investigation of tRNALeu/Lys and ATPase 6 Genes Mutations in Huntington’s Disease

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Prospects for redox-based therapy in neurodegenerative diseases

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Neuroprotective therapy for Huntington’s disease: new prospects and challenges

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Neuroprotective possibilities for Huntington’s disease

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Huntington's disease: The mystery unfolds?

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Oxidative Stress in Huntington’s Disease

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Melatonin reverses the oxidative stress and mitochondrial dysfunction caused by LETM1 silencing

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Vitamin E Status and Neurodegenerative Disease

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6.4 Mitochondrial Permeability Transition in the CNS—Composition, Regulation, and Pathophysiological Relevance

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Systemic Neuroprotection by Chlorogenic Acid: Antioxidant and Anti-inflammatory Evaluation in Early Neurodegeneration Induced by 3-Nitropropionic Acid in Mice

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Mitochondrial Dynamics in Neurodegenerative Diseases

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Surveying the Landscape of Huntington's Disease Mechanisms, Measurements, and Medicines

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Oxidative Damage in Huntington's Disease

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Discovery of Bioactive Small-Molecule Inhibitor of Poly ADP-Ribose Polymerase: Implications for Energy-Deficient Cells

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Nucleocytoplasmic transport of huntingtin and Huntington's disease

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Mitochondria in neurodegeneration

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The Role of Impaired Mitochondrial Transport in the Development of Neurodegenerative Diseases

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Adhesion Regulating Molecule 1 Mediates HAP40 Overexpression-Induced Mitochondrial Defects

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Physiopathologie de la maladie de Huntington : état des connaissances

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Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets

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Translational research in Huntington’s disease: opening up for disease modifying treatment

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Inhibitory effect of 8-oxo-7,8-dihydro-2′-deoxyguanosine on the growth of KG-1 myelosarcoma in Balb/c nude mice

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Thiol-disulfide Oxidoreductases TRX1 and TMX3 Decrease Neuronal Atrophy in a Lentiviral Mouse Model of Huntington’s Disease

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Metabolite measurements in the caudate nucleus, anterior cingulate cortex and hippocampus among patients with mitochondrial disorders: a case-control study using proton magnetic resonance spectroscopy

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Promethazine protects against 3-nitropropionic acid-induced neurotoxicity

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Mitochondrial dysfunction and increased sensitivity to excitotoxicity in mice deficient in DNA mismatch repair

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Mitochondrial Medicine: The Central Role of Cellular Energetic Depression and Mitochondria in Cell Pathophysiology

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Introduction: Immunosuppressants as Neuroprotective Agents

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Chemotherapy-induced neuronal DNA damage: an intriguing toolbox to elucidate DNA repair mechanisms in the brain

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Mono- and Biallelic Inactivation of Huntingtin Gene in Patient-Specific Induced Pluripotent Stem Cells Reveal HTT Roles in Striatal Development and Neuronal Functions

Louessard, M., Cailleret, M., Jarrige, M., Bigarreau, J., Lenoir, S., Dufour, N., Rey, M. J., Saudou, F., Déglon, N., & Perrier, A. L. (2024) · Journal of Huntington s Disease · doi:10.3233/jhd-231509 · Cited by 7

Neurodegeneration Caused by Accumulation of an Oxidized Base Lesion, 8-oxoguanine, in Nuclear and Mitochondrial DNA: From Animal Models to Human Diseases

Nakabeppu, Y. (2016) · WORLD SCIENTIFIC eBooks · doi:10.1142/9789814719735_0015 · Cited by 7

Determining the Fate of Neurons in SCA3: ATX3, a Rising Decision Maker in Response to DNA Stresses and Beyond

Tu, Y., Li, X., Zhu, X., Liu, X., Guo, C., Jia, D., & Tang, T.-S. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.619911 · Cited by 8

Transcriptomic analysis of human endometrial stromal cells during early embryo invasion

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Temporal Characterization of Behavioral and Hippocampal Dysfunction in the YAC128 Mouse Model of Huntington’s Disease

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Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington’s disease model

Jiang, A., You, L., Handley, R. R., Hawkins, V., Reid, S. J., Jacobsen, J. C., Patassini, S., Rudiger, S. R., McLaughlan, C. J., Kelly, J. M., et al. (2024) · Human Molecular Genetics · doi:10.1093/hmg/ddae087 · Cited by 8

Oxidative Changes and Possible Effects of Polymorphism of Antioxidant Enzymes in Neurodegenerative Disease

Babušíková, E., Evinová, A., Hatok, J., Dobrota, D., & Jurecekov, J. (2013) · InTech eBooks · doi:10.5772/54619 · Cited by 8

Doença de Huntington

Gil‐Mohapel, J., & Rego, A. C. (2001) · Revista Neurociências · doi:10.34024/rnc.2011.v19.8332 · Cited by 7

Of mice and men: solving the molecular mysteries of Huntington's disease

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Consequences of Mitochondrial Dysfunction in Huntington's Disease and Protection via Phosphorylation Pathways

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Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: Relevance for transcriptional changes in Huntington disease

Fox, S. N., Savage, C. H., Amireddy, N., McMeekin, L. J., Crossman, D. K., Detloff, P. J., Gray, M., & Cowell, R. M. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106818 · Cited by 8

Role of mitochondria in neuronal function and survival in the enteric and central nervous systems

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The Essential Role of Astrocytes in Neurodegeneration and Neuroprotection

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Pathophysiological Mechanisms of Huntington’s Disease

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Neural Transplantation in Huntington's Disease

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Adenosine Receptors in Huntington’s Disease

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Polyalanine and Polyglutamine Diseases: Possible Common Mechanisms?

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Machado-Joseph Disease / Spinocerebellar Ataxia Type 3

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The Use of the Mitochondrial Toxin 3-NP to Uncover Cellular Dysfunction in Huntington’s Disease

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