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1,3‐Dipolar Cycloadditions of Azides and Alkynes: A Universal Ligation Tool in Polymer and Materials Science

Lutz, Jean‐François·2007·Angewandte Chemie International Edition

Abstract

In 2001, Sharpless and co‐workers introduced “click” chemistry, a new approach in organic synthesis that involves a handful of almost perfect chemical reactions. Among these carefully selected reactions, Huisgen 1,3‐dipolar cycloadditions were shown to be the most effective and versatile and thus became the prime example of click chemistry. Hence, these long‐neglected reactions were suddenly re‐established in organic synthesis and, in particular, have gained popularity in materials science. The number of publications dealing with click chemistry has grown exponentially over the last two years. The Minireview discusses whether click chemistry is a miracle tool or an ephemeral trend.

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Metadata

Authors
Lutz, J.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2007-01-29
Volume
46
Issue
7
Pages
1018-1025
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
OpenAlex
W2171660150
Cited by
1,516
References
6
FWCI
96.71
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: 1,3‐Dipolar Cycloadditions of Azides and Alkynes: A Universal Ligation Tool in Polymer and Materials Science. https://app.cochat.ai/papers/10.1002/anie.200604050
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Lutz, J. (2007). 1,3‐Dipolar Cycloadditions of Azides and Alkynes: A Universal Ligation Tool in Polymer and Materials Science. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.200604050

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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