The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Phage‐Enabled Nanomedicine: From Probes to Therapeutics in Precision Medicine
Open accessAbstract
Both lytic and temperate bacteriophages (phages) can be applied in nanomedicine, in particular, as nanoprobes for precise disease diagnosis and nanotherapeutics for targeted disease treatment. Since phages are bacteria‐specific viruses, they do not naturally infect eukaryotic cells and are not toxic to them. They can be genetically engineered to target nanoparticles, cells, tissues, and organs, and can also be modified with functional abiotic nanomaterials for disease diagnosis and treatment. This Review will summarize the current use of phage structures in many aspects of precision nanomedicine, including ultrasensitive biomarker detection, enhanced bioimaging for disease diagnosis, targeted drug and gene delivery, directed stem cell differentiation, accelerated tissue formation, effective vaccination, and nanotherapeutics for targeted disease treatment. We will also propose future directions in the area of phage‐based nanomedicines, and discuss the state of phage‐based clinical trials.
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Cites
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Cited by
Dong, X., Pan, P., Zheng, D.-W., Bao, P., Zeng, X., & Zhang, X.-Z. (2020) · Science Advances · doi:10.1126/sciadv.aba1590 · Cited by 282
Applications of Phyto-Nanotechnology for the Treatment of Neurodegenerative Disorders
Bhattacharya, T., Soares, G. A. B. E., Chopra, H., Rahman, M. M., Hasan, Z., Swain, S. S., & Cavalu, S. (2022) · Materials · doi:10.3390/ma15030804 · Cited by 259
Intestinal phages interact with bacteria and are involved in human diseases
Shuwen, H., & Kefeng, D. (2022) · Gut Microbes · doi:10.1080/19490976.2022.2113717 · Cited by 124
(2023) · doi:10.1016/j.mtbio.2023.100612 · Cited by 71
Bacteriophages as Potential Clinical Immune Modulators
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Metadata
- Authors
- Sunderland, K. S., Yang, M., & Mao, C.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2017-01-24
- Volume
- 56
- Issue
- 8
- Pages
- 1964-1992
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2476758090
- Cited by
- 171
- References
- 11
- FWCI
- 15.33
- Type
- journal article
- Language
- en
- Open access
- green
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