Osteoblasts engulf apoptotic bodies during alveolar bone formation in the rat maxilla

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

Gavrieli, Y., Sherman, Y., & Ben-Sasson, S. A. (1992) · The Journal of cell biology · doi:10.1083/jcb.119.3.493 · Cited by 9,444 · see citing works

Cell Death: The Significance of Apoptosis

Wyllie, A. H., Kerr, J. F. R., & Currie, A. R. (1980) · International review of cytology · doi:10.1016/s0074-7696(08)62312-8 · Cited by 7,235 · see citing works

Cell Death

Danial, N. N., & Korsmeyer, S. J. (2004) · Cell · doi:10.1016/s0092-8674(04)00046-7 · Cited by 4,651 · see citing works

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis

Manolagas, S. C. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.2.0395 · Cited by 2,575 · see citing works

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis

Manolagas, S. C. (2000) · Endocrine Reviews · doi:10.1210/er.21.2.115 · Cited by 1,318 · see citing works

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

Kraupp, B. G., Ruttkay-Nedecký, B., Koudelka, H., Bukowska, K., Bursch, W., & Schulte‐Hermann, R. (1995) · Hepatology · doi:10.1002/hep.1840210534 · Cited by 1,167 · see citing works

Loss of Osteocyte Integrity in Association with Microdamage and Bone Remodeling After Fatigue In Vivo

Verborgt, O., Gibson, G. J., & Schaffler, M. B. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.1.60 · Cited by 731 · see citing works

Apoptosis, autophagy, and more

Lockshin, R. A., & Zakeri, Z. F. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2004.04.011 · Cited by 701 · see citing works

Cell suicide for beginners

RAFF, M. C. (1998) · Nature · doi:10.1038/24055 · Cited by 692 · see citing works

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells

Fadok, V. A., Savill, J., Haslett, C., Bratton, D. L., Doherty, D. E., Campbell, P. A., & Henson, P. M. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.149.12.4029 · Cited by 596 · see citing works

Molecular Biology of Matrix Vesicles

Anderson, H. C. (1995) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199505000-00034 · Cited by 585 · see citing works

Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines

Jilka, R. L., Weinstein, R. S., Bellido, T., Parfitt, A. M., & Manolagas, S. C. (1998) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1998.13.5.793 · Cited by 578 · see citing works

In situ detection of fragmented DNA (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note*1

Grasl‐Kraupp, B. (1995) · Hepatology · doi:10.1016/0270-9139(95)90071-3 · Cited by 517 · see citing works

To Die or Not to Die

Hetts, S. W. (1998) · JAMA · doi:10.1001/jama.279.4.300 · Cited by 506 · see citing works

Recognizing death: the phagocytosis of apoptotic cells

Platt, N., da Silva, R. P., & Gordon, S. (1998) · Trends in Cell Biology · doi:10.1016/s0962-8924(98)01329-4 · Cited by 375 · see citing works

The Role of Estrogen in the Control of Rat Osteocyte Apoptosis

Tomkinson, A., Gevers, E. F., Wit, J. M., REEVE, J., & Noble, B. (1998) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1998.13.8.1243 · Cited by 302 · see citing works

Death without caspases, caspases without death

Abraham, M. C., & Shaham, S. (2004) · Trends in Cell Biology · doi:10.1016/j.tcb.2004.03.002 · Cited by 302 · see citing works

Molecular and cellular biology of alveolar bone

SODEK, J., & MCKEE, M. D. (2000) · Periodontology 2000 · doi:10.1034/j.1600-0757.2000.2240106.x · Cited by 283 · see citing works

Osteoblasts: novel roles in orchestration of skeletal architecture

Mackie, E. J. (2003) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(03)00107-9 · Cited by 279 · see citing works

Identification of apoptotic changes in osteocytes in normal and pathological human bone

Noble, B. S., Stevens, H., Loveridge, N., & Reeve, J. (1997) · Bone · doi:10.1016/s8756-3282(96)00365-1 · Cited by 230 · see citing works

Recent advances in bone biology provide insight into the pathogenesis of bone diseases.

Boyce, B. F., Hughes, D. E., Wright, K. R., Xing, L., & Dai, A. (1999) · PubMed · Cited by 145 · see citing works

DNA fragmentation during bone formation in neonatal rodents assessed by transferase-mediated end labeling

Bronckers, A. L. J. J., Goei, W., Luo, G., Karsenty, G., D’Souza, R. N., Lyaruu, D. M., & Burger, E. H. (1996) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650110913 · Cited by 145 · see citing works

Apoptotic DNA fragmentation and tissue homeostasis

Zhang, J., & Xu, M. (2002) · Trends in Cell Biology · doi:10.1016/s0962-8924(01)02206-1 · Cited by 134 · see citing works

Aspects of Collagen Mineralization in Hard Tissue Formation

Wiesmann, H., Meyer, U., Plate, U., & Höhling, H. J. (2004) · International review of cytology · doi:10.1016/s0074-7696(04)42003-8 · Cited by 128 · see citing works

Deciphering the apoptotic pathway: All roads lead to death

Lincz, L. F. (1998) · Immunology and Cell Biology · doi:10.1046/j.1440-1711.1998.00712.x · Cited by 123 · see citing works

Staining methods applied to glycol methacrylate embedded tissue sections

Cerri, P. S., & Sasso‐Cerri, E. (2003) · Micron · doi:10.1016/s0968-4328(03)00098-2 · Cited by 117 · see citing works

Apoptosis in murine calvarial bone and suture development

Rice, D. P. C., Kim, H., & Thesleff, I. (1999) · European Journal Of Oral Sciences · doi:10.1046/j.0909-8836.1999.eos107406.x · Cited by 100 · see citing works

Combined TUNEL and TRAP methods suggest that apoptotic bone cells are inside vacuoles of alveolar bone osteoclasts in young rats

Cerri, P. S., Boabaid, F., & Katchburian, E. (2003) · Journal of Periodontal Research · doi:10.1034/j.1600-0765.2003.02006.x · Cited by 57 · see citing works

Apoptotic bone cells may be engulfed by osteoclasts during alveolar bone resorption in young rats

Boabaid, F., Cerri, P. S., & Katchburian, E. (2001) · Tissue and Cell · doi:10.1054/tice.2001.0179 · Cited by 53 · see citing works

Activity‐induced fiber regeneration in rat soleus muscle

Wanek, L., & Snow, M. H. (2000) · The Anatomical Record · doi:10.1002/(sici)1097-0185(20000201)258:2 · Cited by 43 · see citing works

Junctions between Early Developing Osteoblasts of Rat Calvaria as Revealed by Freeze-Fracture and Ultrathin Section Electron Microscopy.

Arana-Chavez, V. E., Soares, A., & Katchburian, E. (1995) · Archivum histologicum japonicum · doi:10.1679/aohc.58.285 · Cited by 42 · see citing works

Apoptosis during intramembranous ossification

Palumbo, C., Ferretti, M., & Pol, A. D. (2003) · Journal of Anatomy · doi:10.1046/j.1469-7580.2003.00247.x · Cited by 34 · see citing works

Degeneration of osteoblasts involved in intramembranous ossification of fetal rat calvaria

Zimmermann, B. A. (1992) · Cell and Tissue Research · doi:10.1007/bf00318693 · Cited by 30 · see citing works

Apoptosis in the early involuting stellate reticulum of rat molar tooth germs

Baratella, L., Arana-Chavez, V. E., & Katchburian, E. (1999) · Anatomy and Embryology · doi:10.1007/s004290050258 · Cited by 22 · see citing works

Ultrastructural and lanthanum tracer examination of rapidly resorbing rat alveolar bone suggests that osteoclasts internalize dying bone cells

Taniwaki, N. N., & Katchburian, E. (1998) · Cell and Tissue Research · doi:10.1007/s004410051109 · Cited by 17 · see citing works

Embryology and Cellular Biology of Bone

Raisz, L. G., & Rodan, G. A. (1998) · Elsevier eBooks · doi:10.1016/b978-012068700-8/50002-5 · Cited by 17 · see citing works

Collagen phagocytosis by cementoblasts at the periodontal ligament-cementum interface.

Yajima, T., Matsuo, A., & Hirai, T. (1989) · Archivum histologicum japonicum · doi:10.1679/aohc.52.521 · Cited by 7 · see citing works

Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells

Florencio-Silva, R., Sasso, G. R. D. S., Sasso-Cerri, E., Simões, M. J., & Cerri, P. S. (2015) · BioMed Research International · doi:10.1155/2015/421746 · Cited by 2,044 · see citing works

Mature osteoclast–derived apoptotic bodies promote osteogenic differentiation via RANKL-mediated reverse signaling

Ma, Q., Liang, M., Wu, Y., Ding, N., Duan, L., Yu, T., Bai, Y., Kang, F., Dong, S., Xu, J., et al. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.007625 · Cited by 107 · see citing works

Extracellular Vesicles Derived From Apoptotic Cells: An Essential Link Between Death and Regeneration

Li, M., Liao, L., & Tian, W. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.573511 · Cited by 104 · see citing works

EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis

Tonna, S. J., Takyar, F. M., Vrahnas, C., Crimeen‐Irwin, B., Ho, P. W. M., Poulton, I. J., Brennan, H. J., McGregor, N. E., Allan, E. H., Nguyen, H., et al. (2014) · The FASEB Journal · doi:10.1096/fj.14-254300 · Cited by 94 · see citing works

Morphological evidences indicate that the interference of cimetidine on the peritubular components is responsible for detachment and apoptosis of Sertoli cells

Sasso‐Cerri, E., & Cerri, P. S. (2008) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-6-18 · Cited by 64 · see citing works

Comparison of immunotherapy mediated by apoptotic bodies, microvesicles and exosomes: apoptotic bodies’ unique anti-inflammatory potential

Wen, J., Creaven, D., Luan, X., & Wang, J. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04342-w · Cited by 58 · see citing works

Effects of estrogen status in osteocyte autophagy and its relation to osteocyte viability in alveolar process of ovariectomized rats

Florencio‐Silva, R., Sasso, G. R. D. S., Sasso‐Cerri, E., Simões, M. D. J., & Cerri, P. S. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.12.089 · Cited by 55 · see citing works

Simvastatin therapy in cyclosporine A‐induced alveolar bone loss in rats

Nassar, P. O., Nassar, C. A., Guimarães, M. R., de Aquino, S. G., Andia, D. C., Muscará, M. N., Spolidório, D. M. P., Rossa, C., & Spolidório, L. C. (2008) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2008.01143.x · Cited by 54 · see citing works

Apoptosis in Bone for Tissue Engineering

Bran, G. M., Stern‐Straeter, J., Hörmann, K., Riedel, F., & GOESSLER, U. R. (2008) · Archives of Medical Research · doi:10.1016/j.arcmed.2008.02.007 · Cited by 45 · see citing works

Decrease in the number and apoptosis of alveolar bone osteoclasts in estrogen‐treated rats

Faloni, A. P. S., Sasso‐Cerri, E., Katchburian, E., & Cerri, P. S. (2007) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2006.00932.x · Cited by 40 · see citing works

Immunohistochemical detection of estrogen receptor β in alveolar bone cells of estradiol‐treated female rats: possible direct action of estrogen on osteoclast life span

Cruzoé‐Souza, M., Sasso‐Cerri, E., & Cerri, P. S. (2009) · Journal of Anatomy · doi:10.1111/j.1469-7580.2009.01158.x · Cited by 38 · see citing works

Immunoinflammatory response and bioactive potential of GuttaFlow bioseal and MTA Fillapex in the rat subcutaneous tissue

Delfino, M. M., Guerreiro‐Tanomaru, J. M., Tanomaru‐Filho, M., Sasso‐Cerri, E., & Cerri, P. S. (2020) · Scientific Reports · doi:10.1038/s41598-020-64041-0 · Cited by 37 · see citing works

Survival of Staphylococcus epidermidis in Fibroblasts and Osteoblasts

Perez, K., & Patel, R. (2018) · Infection and Immunity · doi:10.1128/iai.00237-18 · Cited by 35 · see citing works

Structural and functional changes in the alveolar bone osteoclasts of estrogen‐treated rats

Faloni, A. P. D. S., Sasso‐Cerri, E., Rocha, F. R. G., Katchburian, E., & Cerri, P. S. (2012) · Journal of Anatomy · doi:10.1111/j.1469-7580.2011.01449.x · Cited by 31 · see citing works

Matrix Metalloproteinase-1 and Acid Phosphatase in the Degradation of the Lamina Propria of Eruptive Pathway of Rat Molars

Júnior, J. P. D. P., Sasso‐Cerri, E., & Cerri, P. S. (2018) · Cells · doi:10.3390/cells7110206 · Cited by 31 · see citing works

Increased apoptosis in osteoclasts and decreased RANKL immunoexpression in periodontium of cimetidine‐treated rats

Longhini, R., de Oliveira, P. A., de Souza Faloni, A. P., Sasso‐Cerri, E., & Cerri, P. S. (2013) · Journal of Anatomy · doi:10.1111/joa.12011 · Cited by 23 · see citing works

The phytochemical plumbagin reciprocally modulates osteoblasts and osteoclasts

Yadav, A. M., Bagade, M. M., Ghumnani, S., Raman, S., Saha, B., Kubatzky, K. F., & Ashma, R. (2021) · Biological Chemistry · doi:10.1515/hsz-2021-0290 · Cited by 20 · see citing works

Cell death and quantitative reduction of rests of Malassez according to age

Gonçalves, J. S., Sasso‐Cerri, E., & Cerri, P. S. (2008) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2007.01050.x · Cited by 18 · see citing works

Cimetidine-induced vascular cell apoptosis impairs testicular microvasculature in adult rats.

Beltrame, F. L., Yamauti, C. T., Caneguim, B. H., Cerri, P. S., Miraglia, S. M., & Sasso‐Cerri, E. (2012) · PubMed · doi:10.14670/hh-27.1343 · Cited by 17 · see citing works

Efferocytosis in inflammatory bone disorders

Wen, L., Ye, R., Zhai, W., Li, D., & Sun, H. (2025) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2025.04.001 · Cited by 16 · see citing works

Treatment with tacrolimus enhances alveolar bone formation and decreases osteoclast number in the maxillae: a histomorphometric and ultrastructural study in rats.

Andia, D. C., Nassar, C. A., Nassar, P. O., Guimarães, M. R., Cerri, P. S., & Spolidório, L. C. (2008) · PubMed · doi:10.14670/hh-23.1177 · Cited by 15 · see citing works

Apoptosis and reduced microvascular density of the lamina propria during tooth eruption in rats

Júnior, J. P. D. P., Sasso‐Cerri, E., & Cerri, P. S. (2015) · Journal of Anatomy · doi:10.1111/joa.12359 · Cited by 14 · see citing works

Wettability and pre-osteoblastic behavior evaluations of a dense bovine hydroxyapatite ceramics

Pires, L. A., de Meira, C. R., Tokuhara, C. K., de Oliveira, F. A., Dainezi, V. B., Graeff, M. S. Z., Fortulan, C. A., de Oliveira, R. C., Puppin‐Rontani, R. M., & Borges, A. F. S. (2020) · Journal of Oral Science · doi:10.2334/josnusd.19-0007 · Cited by 13 · see citing works

Area of Rests of Malassez in Young and Adult Rat Molars: Evidences in the Formation of Large Rests

Cerri, P. S., Gonçalves, J. D. S., & Sasso‐Cerri, E. (2008) · The Anatomical Record · doi:10.1002/ar.20826 · Cited by 9 · see citing works

Immunosuppressant Prograf® (Tacrolimus) Induces Histopathological Disorders in the Peritubular Tissue of Rat Testes

Caneguim, B. H., Cerri, P. S., Spolidório, L. C., Miraglia, S. M., & Sasso‐Cerri, E. (2011) · Cells Tissues Organs · doi:10.1159/000322901 · Cited by 7 · see citing works

Reduction of osteoclast formation and survival following suppression of cytokines by diacerein in periodontitis

Oliveira, G. D., Rodrigues, L. D. A., da Silva, A. A. S., Gouvea, L. C., Silva, R. C. L., Sasso‐Cerri, E., & Cerri, P. S. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117086 · Cited by 6 · see citing works

Immunoexpression pattern of autophagy mediators in alveolar bone osteoclasts following estrogen withdrawal in female rats

Florencio‐Silva, R., Sasso, G. R. D. S., Sasso‐Cerri, E., Simões, M. D. J., & Cerri, P. S. (2021) · Journal of Molecular Histology · doi:10.1007/s10735-020-09953-x · Cited by 6 · see citing works

The intravestibular source of the vestibular aqueduct. III: Osseous pathology of Ménière's disease, clarified by a developmental study of the intraskeletal channels of the otic capsule

Michaels, L., & Soucek, S. (2010) · Acta Oto-Laryngologica · doi:10.3109/00016480903443183 · Cited by 4 · see citing works

Diacerein Downregulates Nfkb, Induces ALP Activity and Inhibits Osteoblast Apoptosis in Alveolar Bone of Rats with Periodontitis

Cerri, P. S., Rodrigues, L. D. A., Gouvea, L. C., de Oliveira, G. H., & Cerri, E. S. (2026) · Biomedicines · doi:10.3390/biomedicines14020306 · Cited by 1 · see citing works

The opportunity of using alloplastic bone augmentation materials in the maxillofacial region– Literature review

Bran, S., Băciuț, G., Băciuț, M. F., Mitre, I., Onisor, F. G., Hedesiu, M. C., & Manea, A. (2018) · Particulate Science And Technology · doi:10.1080/02726351.2018.1455784 · Cited by 1 · see citing works

Caracterização morfométrica e molecar do papel da iNOS no processo de reparo ósseo alveolar em condições homeostáticas e infecciosas

Francisconi, C. F. (2013) · doi:10.11606/d.25.2013.tde-14082013-095031

Avaliação do efeito da Sinvastatina em ratos submetidos a periodontite experimental e imunossuprimidos por Ciclosporina-A e Tacrolimus

Nassar, P. O. (2008) · Americanae (AECID Library)

Regeneração óssea guiada utilizando membrana reabsorvível fixada com etilcianoacrilato

Pereira, N. S., Souza, L. R. D. B., Soares, L. C., Santos, Í. M. S. P., & de Araújo, K. S. (2012) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · doi:10.18363/rbo.v68n2.p.233

ALVEOLAR DE RATOS TRATADOS COM CICLOSPORINA-A OU TACROLIMUS

Araraquara, F. D. O. D. (2006)

Modelação matemática para avaliar o risco de fratura por desmineralização óssea

Teixeira, D. J. S. (2014) · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)

Regeneração óssea guiada utilizando membrana reabsorvível fixada com etilcianoacrilato Guided bone regeneration using resorbable membrane fixed with ethyl cyanoacrylate.

Pereira, N. S., Soares, L. C., Santos, Í. M. S. P., Portela, S., & de Araújo, K. S. (2012)

Effect of Grape Juice Consumption and Red Wine in the Osteoprotegerin Level and Systolic Blood Pressure in Rats Wistar Fed High - Fat Diet

Bedê, T. P. (2016) · International Journal of Nutrition and Food Sciences · doi:10.11648/j.ijnfs.20160503.13

Novel Events in Cartilage Remodeling During Endochondral Bone Formation

Soliman, S. A. (2014)

Impacto do tabagismo na composição da matriz extracelular óssea: modelo de fratura de tíbia em camundongos

Barbosa, A. P. (2019) · doi:10.11606/t.5.2019.tde-21082019-092319

Efeitos da radiação ionizante nas proteínas presentes em ossos humanos desmineralizados, liofilizados ou congelados

Antebi, U. (2015) · doi:10.11606/d.85.2015.tde-06102015-102027

References

(2015) · Elsevier eBooks · doi:10.1016/b978-0-12-416678-3.00059-8

Effects of differential and combinatorial inhibition of myostatin and activin A in the G610 murine model of osteogenesis imperfecta

Omosule, C. L. (2021) · doi:10.32469/10355/90078

Análise comparativa da integração de enxertos alógenos liofilizados e irradiados versus enxertos xenógenos em áreas submetidas à cirurgia de levantamento de seio maxilar bilateral para implantes dentários

Hayek, R. R. A. (2023) · doi:10.11606/t.85.2023.tde-06062023-154353

Análise morfológica dos efeitos do tratamento tópico da melatonina associada à esponja de colágeno e à proteína rhbmp-2 sobre o remodelamento ósseo

Montarele, L. F. (2023) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.58.2023.tde-23102023-155043

Effects of Vitamin C and E Supplementation with High-Intensity Swimming on Bone Adaption in Mice

Sari, G. M., Swannjo, J. B., Arifandi, Y. A., Herawati, L., Irwadi, I., & Ananta, S. M. (2024) · Current Research in Nutrition and Food Science Journal · doi:10.12944/crnfsj.12.3.26

Apoptotic bone cells may be engulfed by osteoclasts during alveolar bone resorption in young rats

Boabaid, F., Cerri, P. S., & Katchburian, E. (2001) · Tissue and Cell · doi:10.1054/tice.2001.0179 · Cited by 53 · see citing works

Combined TUNEL and TRAP methods suggest that apoptotic bone cells are inside vacuoles of alveolar bone osteoclasts in young rats

Cerri, P. S., Boabaid, F., & Katchburian, E. (2003) · Journal of Periodontal Research · doi:10.1034/j.1600-0765.2003.02006.x · Cited by 57 · see citing works

Ultrastructural and lanthanum tracer examination of rapidly resorbing rat alveolar bone suggests that osteoclasts internalize dying bone cells

Taniwaki, N. N., & Katchburian, E. (1998) · Cell and Tissue Research · doi:10.1007/s004410051109 · Cited by 17 · see citing works

Apoptose durante a reabsorção do osso alveolar e erupção dental em ratos

Boabaid, F. (2000) · UNIFESP Institutional Repository (Universidade Federal de São Paulo)

Apoptotic Bodies Convey Activity Capable of Initiating Osteoclastogenesis and Localized Bone Destruction

Kogianni, G., Mann, V., & Noble, B. (2008) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.080207 · Cited by 221 · see citing works