Cooperation between C1q and DNase I in the clearance of necrotic cell–derived chromatin

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

Nicoletti, I., Migliorati, G., Pagliacci, M. C., Grignani, F., & Riccardi, C. (1991) · Journal of Immunological Methods · doi:10.1016/0022-1759(91)90198-o · Cited by 4,580 · see citing works

Features of apoptotic cells measured by flow cytometry

Darżynkiewicz, Z., Bruno, S., Bino, G. D., Gorczyca, W., Hotz, M. A., Lassota, P., & Traganos, F. (1992) · Cytometry · doi:10.1002/cyto.990130802 · Cited by 1,885 · see citing works

Endonuclease G is an apoptotic DNase when released from mitochondria

Li, L. Y., Luo, X., & Wang, X. (2001) · Nature · doi:10.1038/35083620 · Cited by 1,787 · see citing works

A blast from the past: clearance of apoptotic cells regulates immune responses

Savill, J., Dransfield, I., Gregory, C. D., & Haslett, C. (2002) · Nature reviews. Immunology · doi:10.1038/nri957 · Cited by 1,574 · see citing works

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

Botto, M., Dell' Agnola, C., Bygrave, A. E., Thompson, E. M., Cook, H. T., Petry, F., Loos, M., Pandolfi, P. P., & Walport, M. J. (1998) · Nature Genetics · doi:10.1038/ng0598-56 · Cited by 1,434 · see citing works

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway

Basu, S., Binder, R. J., Suto, R., Anderson, K. M., & Srivastava, P. K. (2000) · International Immunology · doi:10.1093/intimm/12.11.1539 · Cited by 1,305 · see citing works

Phagocytosis and clearance of apoptotic cells is mediated by MER

Scott, R. S., McMahon, E. J., Pop, S. M., Reap, E. A., Caricchio, R., Cohen, P. L., Earp, H. S., & Matsushima, G. K. (2001) · Nature · doi:10.1038/35075603 · Cited by 1,215 · see citing works

C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells

Ogden, C. A., deCathelineau, A. M., Hoffmann, P. R., Bratton, D. L., Ghebrehiwet, B., Fadok, V. A., & Henson, P. M. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.6.781 · Cited by 1,148 · see citing works

CD91 Is a Common Receptor for Heat Shock Proteins gp96, hsp90, hsp70, and Calreticulin

Basu, S., Binder, R. J., Ramalingam, T. R., & Srivastava, P. K. (2001) · Immunity · doi:10.1016/s1074-7613(01)00111-x · Cited by 1,123 · see citing works

Features of systemic lupus erythematosus in Dnase1-deficient mice

Napirei, M., Karsunky, H., Zevnik, B., Stephan, H., Mannherz, H. G., & Möröy, T. (2000) · Nature Genetics · doi:10.1038/76032 · Cited by 789 · see citing works

Complement-dependent Clearance of Apoptotic Cells by Human Macrophages

Mevorach, D., Mascarenhas, J., Gershov, D., & Elkon, K. (1998) · Journal of Experimental Medicine · doi:10.1084/jem.188.12.2313 · Cited by 776 · see citing works

C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited

Korb, L. C., & Ahearn, J. M. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.10.4525 · Cited by 659 · see citing works

Actin Is the Naturally Occurring Inhibitor of Deoxyribonuclease I

Lazarides, E., & Lindberg, U. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.12.4742 · Cited by 634 · see citing works

Mutation of DNASE1 in people with systemic lupus erythematosus

Yasutomo, K., Horiuchi, T., Kagami, S., Tsukamoto, H., Hashimura, C., Urushihara, M., & Kuroda, Y. (2001) · Nature Genetics · doi:10.1038/91070 · Cited by 598 · see citing works

Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity

Bickerstaff, M., Botto, M., Hutchinson, W., Herbert, J., Tennent, G., Bybee, A., Mitchell, D., Cook, H., Butler, P., Walport, M., et al. (1999) · Nature Medicine · doi:10.1038/9544 · Cited by 548 · see citing works

Granulocyte Apoptosis and Its Role in the Resolution and Control of Lung Inflammation

Haslett, C. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.supplement_1.4 · Cited by 517 · see citing works

Mitochondria, the killer organelles and their weapons

Ravagnan, L., Roumier, T., & Kroemer, G. (2002) · Journal of Cellular Physiology · doi:10.1002/jcp.10111 · Cited by 484 · see citing works

Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation

Sahara, S., Aoto, M., Eguchi, Y., Imamoto, N., Yoneda, Y., & Tsujimoto, Y. (1999) · Nature · doi:10.1038/43678 · Cited by 431 · see citing works

Inflammation in the course of early myocardial ischemia

Entman, M. L., Michael, L., Rossen, R. D., Dreyer, W. J., Anderson, D. C., Taylor, A. A., & Smith, C. W. (1991) · The FASEB Journal · doi:10.1096/fasebj.5.11.1868978 · Cited by 387 · see citing works

Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM

Boes, M. L., Schmidt, T., Linkemann, K., Beaudette-Zlatanova, B. C., Marshak‐Rothstein, A., & Chen, J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1184 · Cited by 370 · see citing works

The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells

Rovere, P. Q., Peri, G., Fazzini, F., Bottazzi, B., Doni, A., Bondanza, A., Zimmermann, V. S., Garlanda, C., Fascio, U., Sabbadini, M. G., et al. (2000) · Blood · doi:10.1182/blood.v96.13.4300 · Cited by 326 · see citing works

The phosphatidylserine receptor: a crucial molecular switch?

Henson, P. M., Bratton, D. L., & Fadok, V. A. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35085094 · Cited by 321 · see citing works

Evaluation of the structure-modifying effects of diacerein in hip osteoarthritis: ECHODIAH, a three-year, placebo-controlled trial

Dougados, M., Nguyen, M., Berdah, L., Mazi�res, B., Vignon, E. P., Lequesne, M. G., & for the ECHODIAH Investigators Study Group (2001) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200111)44:11 · Cited by 320 · see citing works

Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor ? and interleukin-1 in rheumatoid arthritis

Paleolog, E. M., Young, S., Stark, A. C., McCloskey, R. V., Feldmann, M., & Maini, R. N. (1998) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199807)41:7 · Cited by 318 · see citing works

The Globular Heads of C1q Specifically Recognize Surface Blebs of Apoptotic Vascular Endothelial Cells

Navratil, J. S., Watkins, S. C., Wisnieski, J. J., & Ahearn, J. M. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.5.3231 · Cited by 262 · see citing works

Deficiency in Serum Immunoglobulin (Ig)m Predisposes to Development of Igg Autoantibodies

Ehrenstein, M. R., Cook, H. T., & Neuberger, M. S. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.191.7.1253 · Cited by 246 · see citing works

Complement and apoptosis

Fishelson, Z. (2001) · Molecular Immunology · doi:10.1016/s0161-5890(01)00055-4 · Cited by 190 · see citing works

Circulating plasma levels of nucleosomes in patients with systemic lupus erythematosus. Correlation with serum antinucleosome antibody titers and absence of clear association with disease activity

Amoura, Z., Pietté, J. C., Chabre, H., Cacoub, P., Papo, T., Wechsler, B., Bach, J., & Koutouzov, S. (1997) · Arthritis & Rheumatism · doi:10.1002/art.1780401217 · Cited by 178 · see citing works

Serum deoxyribonuclease I and clinical activity in systemic lupus erythematosus

Chitrabamrung, S., Rubin, R. L., & Tan, E. M. (1981) · Rheumatology International · doi:10.1007/bf00541153 · Cited by 160 · see citing works

Complement binding is an early feature of necrotic and a rather late event during apoptotic cell death

Gaipl, U. S., Kuenkele, S., Voll, R. E., Beyer, T. D., Kolowos, W., Heyder, P., Kalden, J. R., & i, M. H. (2001) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4400826 · Cited by 159 · see citing works

Lupus, DNase and defective disposal of cellular debris

Walport, M. J. (2000) · Nature Genetics · doi:10.1038/75963 · Cited by 146 · see citing works

Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritis

Berden, J. H. M., Licht, R., van Bruggen, M. C. J., & Tax, W. J. M. (1999) · Current Opinion in Nephrology & Hypertension · doi:10.1097/00041552-199905000-00005 · Cited by 144 · see citing works

Etiopathogenesis of systemic lupus erythematosus

i, M. H., Voll, R. E., & Kalden, J. R. (2000) · Immunology Today · doi:10.1016/s0167-5699(00)01675-3 · Cited by 141 · see citing works

A Role of the Ca2+/Mg2+-dependent Endonuclease in Apoptosis and Its Inhibition by Poly(ADP-ribose) Polymerase

Yakovlev, A. G., Wang, G., Stoica, B. A., Boulares, H. A., Spoonde, A. Y., Yoshihara, K., & Smulson, M. E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001087200 · Cited by 131 · see citing works

Condensed matter in cell death

Zamzami, N., & Kroemer, G. (1999) · Nature · doi:10.1038/43591 · Cited by 122 · see citing works

Immune Response of a Patient with Deficiency of the Fourth Component of Complement and Systemic Lupus Erythematosus

Jackson, C. G., Ochs, H. D., & WEDGWOOD, R. J. P. (1979) · New England Journal of Medicine · doi:10.1056/nejm197905173002002 · Cited by 120 · see citing works

Chromatin-Independent Binding of Serum Amyloid P Component to Apoptotic Cells

Familian, A., Zwart, B., Huisman, H. G., Rensink, I., Roem, D., Hordijk, P. L., Aarden, L. A., & Hack, C. E. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.2.647 · Cited by 117 · see citing works

Pentraxin-chromatin interactions: serum amyloid P component specifically displaces H1-type histones and solubilizes native long chromatin

Butler, P., Tennent, G., & Pepys, M. (1990) · Journal of Experimental Medicine · doi:10.1084/jem.172.1.13 · Cited by 112 · see citing works

Solution Structure of the CIDE-N Domain of CIDE-B and a Model for CIDE-N/CIDE-N Interactions in the DNA Fragmentation Pathway of Apoptosis

Lugovskoy, A. A., Zhou, P., Chou, J. J., McCarty, J. S., Li, P., & Wagner, G. (1999) · Cell · doi:10.1016/s0092-8674(00)81672-4 · Cited by 108 · see citing works

Molecular basis of polymorphisms of human complement component C3.

Botto, M., Fong, K. Y., So, A. K. L., Koch, C., & Walport, M. J. (1990) · The Journal of Experimental Medicine · doi:10.1084/jem.172.4.1011 · Cited by 96 · see citing works

Treatment with annexin V increases immunogenicity of apoptotic human T-cells in Balb/c mice

Stach, C. M., Turnay, J., Voll, R. E., Kern, P. M., Kolowos, W., Beyer, T. D., Kalden, J. R., & i, M. H. (2000) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4400715 · Cited by 89 · see citing works

Pharmacodynamics of recombinant human DNase I in serum

Prince, W. S., Baker, D. L., Dodge, A., Ahmed, A. E. E., Chestnut, R. W., & Sinicropi, D. V. (1998) · Clinical & Experimental Immunology · doi:10.1046/j.1365-2249.1998.00647.x · Cited by 77 · see citing works

Implications of CAD and DNase II in ischemic neuronal necrosis specific for the primate hippocampus

Tsukada, T., Watanabe, M., & Yamashima, T. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00679.x · Cited by 68 · see citing works

Involvement of DNase γ in Apoptosis Associated with Myogenic Differentiation of C2C12 Cells

Shiokawa, D., Kobayashi, T., & Tanuma, S. I. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204038200 · Cited by 58 · see citing works

Complement mediated cell death is associated with DNA fragmentation

Cragg, M. S., Howatt, W. J., Bloodworth, L., Anderson, V. A., Morgan, B. P., & Glennie, M. J. (2000) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4400627 · Cited by 55 · see citing works

Activation of the alternative pathway of complement by Entamoeba histolytica.

Ortíz-Ortíz, L., Capín, R., Capin, N. R., Sepúlveda, B., & Zamacona, G. (1978) · PubMed Central · Cited by 54 · see citing works

Complete functional C1q deficiency associated with systemic lupus erythematosus (SLE)

Kirschfink, M., Petry, F., Khirwadkar, K., Wigand, R., Kaltwasser, J. P., & Loos, M. (1993) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.1993.tb03442.x · Cited by 45 · see citing works

DNaseY: A Rat DNaseI-like Gene Coding for a Constitutively Expressed Chromatin-Bound Endonuclease‡

Liu, Q. Y., Pandey, S., Singh, R. K., Lin, W., Ribecco, M. T. S., Borowy‐Borowski, H., Smith, B., Leblanc, J. E., Walker, P. R., & Sikorska, M. (1998) · Biochemistry · doi:10.1021/bi9800597 · Cited by 44 · see citing works

Etiopathogenesis of Systemic Lupus Erythematosus

i, M. H., Winkler, T., Gaipl, U. S., Lorenz, H., Geiler, T., & Kalden, J. R. (2000) · International Archives of Allergy and Immunology · doi:10.1159/000024421 · Cited by 43 · see citing works

Immune response to DNA in systemic lupus erythematosus.

Pisetsky, D. S. (2001) · PubMed · Cited by 30 · see citing works

The bovine complement system.

Linscott, W. D., & Triglia, R. P. (1981) · PubMed · Cited by 25 · see citing works

The distribution of cofilin and DNase I in vivo

CHHABRA, D., Bao, S., & dos Remedios, C. G. (2002) · Cell Research · doi:10.1038/sj.cr.7290126 · Cited by 22 · see citing works

Caspase-3-dependent and caspase-3-independent pathways leading to chromatin DNA fragmentation in HL-60 cells

Meng, X. W., Fraser, M. J., Feller, J. M., & Ziegler, J. B. (2000) · APOPTOSIS · doi:10.1023/a:1009689710184 · Cited by 21 · see citing works

Deficient expression of antibodies specific for bacterial DNA by patients with systemic lupus erythematosus.

Ds, P., & Dm, D. (1997) · PubMed · Cited by 21 · see citing works

Preferential sites of early DNA cleavage in apoptosis and the pathway of nuclear damage

Krystosek, A. (1999) · Histochemistry and Cell Biology · doi:10.1007/s004180050357 · Cited by 20 · see citing works

DNASE I mutation and systemic lupus erythematosus in a Spanish population: Comment on the article by Tew et al

Balada, E., Ordi‐Ros, J., Hernanz, S., Villarreal, J. S. C., Cortes, F., Vilardell, M., & Labrador‐Horrillo, M. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10349 · Cited by 18 · see citing works

A nonsense mutation in exon 2 of the DNase I gene is not present in UK subjects with systemic lupus erythematosus and Graves' disease: Comment on the article by Rood et al

Simmonds, M. J., Heward, J. M., Kelly, M. A., Allahabadia, A., Foxall, H., Gordon, C., Franklyn, J. A., & Gough, S. C. L. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10414 · Cited by 16 · see citing works

DNase I Primary Transcript Is Alternatively Spliced in Both Normal and Apoptotic Cells: No Evidence of Up-Regulation in Apoptosis

LIU, Q. Y., Ribecco, M. T. S., HOU, Y., Walker, P. R., & Sikorska, M. (1997) · DNA and Cell Biology · doi:10.1089/dna.1997.16.911 · Cited by 12 · see citing works

Crystallization of cytoplasmic actin in complex with deoxyribonuclease I

Mannherz, H. G., Kabsch, W., Suck, D., Friebel, K., & Frimmer, M. (1985) · Biochemical Journal · doi:10.1042/bj2250517 · Cited by 8 · see citing works

Untitled work

Wilson (1999) · doi:10.1002/1529-0131(199907)42:7

Untitled work

(2002) · doi:10.1002/1521-4141(200206)32:6

New insights into the immunopathogenesis of systemic lupus erythematosus

Tsokos, G. C., Lo, M. S., Costa‐Reis, P., & Sullivan, K. E. (2016) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2016.186 · Cited by 1,225 · see citing works

Organoids

Zhao, Z., Chen, X., Dowbaj, A. M., Sljukic, A., Bratlie, K., Lin, L., Fong, E. L. S., Balachander, G. M., Chen, Z., Soragni, A., et al. (2022) · Nature Reviews Methods Primers · doi:10.1038/s43586-022-00174-y · Cited by 1,001 · see citing works

Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease

Leffler, J., Martin, M., Gullstrand, B., Tydén, H., Lood, C., Truedsson, L., Bengtsson, A. A., & Blom, A. M. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1102404 · Cited by 519 · see citing works

Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process

Farrera, C., & Fadeel, B. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300436 · Cited by 447 · see citing works

Molecular mechanisms of late apoptotic/necrotic cell clearance

Poon, I. K. H., Hulett, M. D., & Parish, C. R. (2009) · Cell Death and Differentiation · doi:10.1038/cdd.2009.195 · Cited by 353 · see citing works

Clearance Deficiency and Cell Death Pathways: A Model for the Pathogenesis of SLE

Mahajan, A., i, M. H., & Munoz, L. E. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00035 · Cited by 309 · see citing works

Cell-Free DNA as a Biomarker in Autoimmune Rheumatic Diseases

Duvvuri, B., & Lood, C. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00502 · Cited by 282 · see citing works

The immune response to secondary necrotic cells

Sachet, M., Liang, Y. Y., & Oehler, R. (2017) · Apoptosis · doi:10.1007/s10495-017-1413-z · Cited by 282 · see citing works

Clearance deficiency and systemic lupus erythematosus (SLE)

Gaipl, U. S., Munoz, L. E., Grossmayer, G., Lauber, K., Franz, S., Sarter, K., Voll, R. E., Winkler, T., Kuhn, A., Kalden, J., et al. (2007) · Journal of Autoimmunity · doi:10.1016/j.jaut.2007.02.005 · Cited by 277 · see citing works

Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro‐inflammatory and anti‐inflammatory agents: key role for TNF‐α

Michlewska, S., Dransfield, I., Megson, I. L., & Rossi, A. G. (2008) · The FASEB Journal · doi:10.1096/fj.08-121228 · Cited by 228 · see citing works

Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation

Marsman, G., Zeerleder, S. S., & Luken, B. M. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.410 · Cited by 227 · see citing works

Impaired clearance of dying cells in systemic lupus erythematosus

Gaipl, U. S., Voll, R. E., Sheriff, A., Franz, S., Kalden, J. R., & i, M. H. (2004) · Autoimmunity Reviews · doi:10.1016/j.autrev.2004.10.007 · Cited by 212 · see citing works

Phagocytosis of Necrotic Debris at Sites of Injury and Inflammation

Westman, J., Grinstein, S., & Marques, P. E. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.03030 · Cited by 206 · see citing works

SLE—a disease of clearance deficiency?

Munoz, L. E., Gaipl, U. S., Franz, S., Sheriff, A., Voll, R. E., Kalden, J. R., & i, M. H. (2005) · Lara D. Veeken · doi:10.1093/rheumatology/keh693 · Cited by 202 · see citing works

Role of complement and complement regulators in the removal of apoptotic cells

Trouw, L. A., Blom, A. M., & Gasque, P. (2007) · Molecular Immunology · doi:10.1016/j.molimm.2007.09.008 · Cited by 192 · see citing works

Extracellular DNA traps in inflammation, injury and healing

Daniel, C., Leppkes, M., Munoz, L. E., Schley, G., Schett, G. A., & i, M. H. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0163-2 · Cited by 189 · see citing works

Clearance of Apoptotic Cells in Human SLE

Gaipl, U. S., Kuhn, A., Sheriff, A., Munoz, L. E., Franz, S., Voll, R. E., Kalden, J. R., & i, M. H. (2005) · KARGER eBooks · doi:10.1159/000090781 · Cited by 170 · see citing works

Autoimmunity and chronic inflammation — Two clearance-related steps in the etiopathogenesis of SLE

Munoz, L. E., Janko, C., Schulze, C., Schorn, C., Sarter, K., Schett, G. A., & i, M. H. (2010) · Autoimmunity Reviews · doi:10.1016/j.autrev.2010.08.015 · Cited by 156 · see citing works

Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population

Tao, K., Fujii, M., Tsukumo, S., Maekawa, Y., Kishihara, K., Kimoto, Y., Horiuchi, T., Hisaeda, H., Akira, S., Kagami, S., et al. (2007) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2006.065961 · Cited by 168 · see citing works

Insights from Mendelian Interferonopathies: Comparison of CANDLE, SAVI with AGS, Monogenic Lupus

Kim, H., Sanchez, G. A. M., & Goldbach‐Mansky, R. T. (2016) · Journal of Molecular Medicine · doi:10.1007/s00109-016-1465-5 · Cited by 137 · see citing works

Systemic activation of NLRP3 inflammasome in patients with severe primary Sjögren's syndrome fueled by inflammagenic DNA accumulations

Vakrakou, A. G., Boiu, S., Ziakas, P. D., Xingi, E., Boleti, H., & Manoussakis, M. N. (2018) · Journal of Autoimmunity · doi:10.1016/j.jaut.2018.02.010 · Cited by 135 · see citing works

The complement cascade as a mediator of tissue growth and regeneration

Rutkowski, M. J., Sughrue, M. E., Kane, A. J., Ahn, B. J., Fang, S., & Parsa, A. T. (2010) · Inflammation Research · doi:10.1007/s00011-010-0220-6 · Cited by 133 · see citing works

Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus

Munoz, L. E., Janko, C., Grossmayer, G. E., Frey, B., Voll, R. E., Kern, P., Kalden, J. R., Schett, G. A., Fietkau, R., i, M. H., et al. (2009) · Arthritis & Rheumatism · doi:10.1002/art.24535 · Cited by 119 · see citing works

Extracellular traps and macrophages: new roles for the versatile phagocyte

Boe, D. M., Curtis, B. J., Chen, M. M., Ippolito, J. A., & Kovacs, E. J. (2015) · Journal of Leukocyte Biology · doi:10.1189/jlb.4ri1014-521r · Cited by 117 · see citing works

NETs: the missing link between cell death and systemic autoimmune diseases?

Darrah, E., & Andrade, F. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00428 · Cited by 115 · see citing works

Nucleic acids and endosomal pattern recognition: how to tell friend from foe?

Brencicova, E., & Diebold, S. S. (2013) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2013.00037 · Cited by 114 · see citing works

Bonding the foe – NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals

Schorn, C., Janko, C., Krenn, V., Zhao, Y., Munoz, L. E., Schett, G. A., & i, M. H. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00376 · Cited by 112 · see citing works

C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation

Trouw, L. A., Nilsson, S. C., Gonçalves, I., Landberg, G., & Blom, A. M. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20050189 · Cited by 112 · see citing works

Inflammatory etiopathogenesis of systemic lupus erythematosus: an update

i, M. H., Podolska, M. J., Biermann, M. H. C., Maueröder, C., & Hahn, J. (2015) · Journal of Inflammation Research · doi:10.2147/jir.s70325 · Cited by 105 · see citing works

Complement in Lupus Nephritis: New Perspectives

Bao, L., Cunningham, P. N., & Quigg, R. J. (2015) · Kidney Diseases · doi:10.1159/000431278 · Cited by 105 · see citing works

The immune functions of phosphatidylserine in membranes of dying cells and microvesicles

Frey, B., & Gaipl, U. S. (2010) · Seminars in Immunopathology · doi:10.1007/s00281-010-0228-6 · Cited by 97 · see citing works

Involvement of phosphatidylserine, αvβ3, CD14, CD36, and complement C1q in the phagocytosis of primary necrotic lymphocytes by macrophages

Böttcher, A., Gaipl, U. S., Fürnrohr, B. G., i, M. H., Girkontaitė, I., Kalden, J. R., & Voll, R. E. (2006) · Arthritis & Rheumatism · doi:10.1002/art.21660 · Cited by 93 · see citing works

Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players

Kruse, K., Janko, C., Urbonaviciute, V., Mierke, C. T., Winkler, T., Voll, R. E., Schett, G. A., Munoz, L. E., & i, M. H. (2010) · APOPTOSIS · doi:10.1007/s10495-010-0478-8 · Cited by 92 · see citing works

Inefficient Clearance of Dying Cells and Autoreactivity

Gaipl, U. S., Sheriff, A., Franz, S., Munoz, L. E., Voll, R. E., Kalden, J. R., & i, M. H. (2006) · Springer eBooks · doi:10.1007/3-540-29714-6_8 · Cited by 90 · see citing works

Genetics of SLE: mechanistic insights from monogenic disease and disease-associated variants

Vinuesa, C. G., Shen, N., & Ware, T. (2023) · Nature Reviews Nephrology · doi:10.1038/s41581-023-00732-x · Cited by 83 · see citing works

Complement deficiencies in humans and animals: Links to autoimmunity

Lewis, M., & Botto, M. (2006) · Autoimmunity · doi:10.1080/08916930600739233 · Cited by 83 · see citing works

Complement, interferon and lupus

Elkon, K. B., & Santer, D. M. (2012) · Current Opinion in Immunology · doi:10.1016/j.coi.2012.08.004 · Cited by 81 · see citing works

Inflammatory clearance of apoptotic remnants in systemic lupus erythematosus (SLE)

Janko, C., Schorn, C., Grossmayer, G. E., Frey, B., i, M. H., Gaipl, U. S., & Munoz, L. E. (2008) · Autoimmunity Reviews · doi:10.1016/j.autrev.2008.07.015 · Cited by 79 · see citing works

Autoimmunity versus tolerance: Can dying cells tip the balance?

Viorritto, I. C. B., Nikolov, N. P., & Siegel, R. M. (2006) · Clinical Immunology · doi:10.1016/j.clim.2006.07.012 · Cited by 78 · see citing works

Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis

Zykova, S. N., Tveita, A. A., & Rekvig, O. P. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012096 · Cited by 78 · see citing works

Neutrophils’ Extracellular Trap Mechanisms: From Physiology to Pathology

Schoen, J., Euler, M., Schauer, C., Schett, G. A., i, M. H., Knopf, J., & Yaykaşlı, K. O. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112855 · Cited by 76 · see citing works

The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: dendritic cells as potential targets

Biermann, M. H. C., Veissi, S., Maueröder, C., Chaurio, R. A., Berens, C., i, M. H., & Munoz, L. E. (2014) · Expert Review of Clinical Immunology · doi:10.1586/1744666x.2014.944162 · Cited by 77 · see citing works

DNase 1 activity in patients with systemic lupus erythematosus: relationship with epidemiological, clinical, immunological and therapeutical features

Martínez‐Valle, F., Balada, E., Ordi‐Ros, J., Buján-Rivas, S., Sellas, A., & Vilardell, M. (2009) · Lupus · doi:10.1177/0961203308098189 · Cited by 76 · see citing works

Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids

Lauber, K., Keppeler, H., Munoz, L. E., Koppe, U., Schröder, K., Yamaguchi, H., Krönke, G., Uderhardt, S., Wesselborg, S., Belka, C., et al. (2013) · Cell Death and Differentiation · doi:10.1038/cdd.2013.82 · Cited by 73 · see citing works

Apoptosis and systemic lupus erythematosus

Sheriff, A., Gaipl, U. S., Voll, R. E., Kalden, J. R., & i, M. H. (2004) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2004.04.006 · Cited by 71 · see citing works

Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling

Böhm, B. B., Aigner, T. G., Roy, B., Brodie, T. A., Blobel, C., & Burkhardt, H. (2005) · Arthritis & Rheumatism · doi:10.1002/art.20974 · Cited by 66 · see citing works

Chance, genetics, and the heterogeneity of disease and pathogenesis in systemic lupus erythematosus

Marion, T. N., & Postlethwaite, A. E. (2014) · Seminars in Immunopathology · doi:10.1007/s00281-014-0440-x · Cited by 64 · see citing works

Circulating Free DNA and Its Emerging Role in Autoimmune Diseases

Mondelo‐Macía, P., Castro, P. G., Castillo‐García, A., Muinelo‐Romay, L., & Díaz‐Peña, R. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11020151 · Cited by 66 · see citing works

A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources

Leffler, J., Ciacma, K., Gullstrand, B., Bengtsson, A. A., Martin, M., & Blom, A. M. (2015) · Arthritis Research & Therapy · doi:10.1186/s13075-015-0726-y · Cited by 55 · see citing works

Advancing Organoid Engineering for Tissue Regeneration and Biofunctional Reconstruction

Jin, H., Xue, Z., Liu, J., Ma, B., Yang, J., & Lei, L. (2024) · Biomaterials Research · doi:10.34133/bmr.0016 · Cited by 53 · see citing works

Cell-free DNA beyond a biomarker for rejection: Biological trigger of tissue injury and potential therapeutics

Tsuji, N., & Agbor-Enoh, S. T. (2021) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2021.03.007 · Cited by 51 · see citing works

Cooperation of Factor VII–Activating Protease and Serum DNase I in the Release of Nucleosomes From Necrotic Cells

Stephan, F., Marsman, G., Bakker, L. M., Bulder, I., Stavenuiter, F., Aarden, L. A., & Zeerleder, S. S. (2013) · Arthritis & Rheumatology · doi:10.1002/art.38265 · Cited by 50 · see citing works

Extracellular histones as damage-associated molecular patterns in neuroinflammatory responses

Richards, C. M., McRae, S. A., Ranger, A. L., & Klegeris, A. (2022) · Reviews in the Neurosciences · doi:10.1515/revneuro-2022-0091 · Cited by 50 · see citing works

Acute DNase1 treatment improves left ventricular remodeling after myocardial infarction by disruption of free chromatin

Vogel, B., Shinagawa, H., Hofmann, U., Ertl, G., & Frantz, S. (2015) · Basic Research in Cardiology · doi:10.1007/s00395-015-0472-y · Cited by 49 · see citing works

The Role of Extracellular DNA in Autoimmunity in SLE

Su, K., & Pisetsky, D. S. (2009) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.2009.02300.x · Cited by 49 · see citing works

Neutrophil extracellular traps-associated markers are elevated in patients with systemic lupus erythematosus

Jeremić, I., Djurić, O., Nikolic, M. M., Vlajnic, M., Nikolić, A., Radojkovic, D. P., & Nikolic, B. B. (2019) · Rheumatology International · doi:10.1007/s00296-019-04426-1 · Cited by 46 · see citing works

Apoptotic molecular mechanisms implicated in autoimmune diseases.

Cacciapaglia, F., Spadaccio, C., Chello, M., Gigante, A., Coccia, R., Afeltra, A., & Amoroso, A. (2009) · PubMed · Cited by 46 · see citing works

Control of apoptosis in autoimmunity

Maniati, E., Potter, P. K., Rogers, N., & Morley, B. (2007) · The Journal of Pathology · doi:10.1002/path.2270 · Cited by 45 · see citing works

Clearance of dying cells and autoimmunity

Michlewska, S., McColl, A., Rossi, A. G., Megson, I. L., & Dransfield, I. (2007) · Autoimmunity · doi:10.1080/08916930701357208 · Cited by 42 · see citing works

Histidine-rich Glycoprotein Specifically Binds to Necrotic Cells via Its Amino-terminal Domain and Facilitates Necrotic Cell Phagocytosis

Jones, A. L., Poon, I. K. H., Hulett, M. D., & Parish, C. R. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m504384200 · Cited by 40 · see citing works

Nucleic acid‐mediated inflammatory diseases

Rigby, R. E., Leitch, A., & Jackson, A. P. (2008) · BioEssays · doi:10.1002/bies.20808 · Cited by 38 · see citing works

Incomplete clearance of apoptotic cells in systemic lupus erythematosus: pathogenic role and potential biomarker

Jung, J., & Suh, C. (2015) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.12568 · Cited by 36 · see citing works

Missing in action—The meaning of cell death in tissue damage and inflammation

Munoz, L. E., Leppkes, M., Fuchs, T. A., Hoffmann, M. H., & i, M. H. (2017) · Immunological Reviews · doi:10.1111/imr.12569 · Cited by 36 · see citing works

Defects in the disposal of dying cells lead to autoimmunity

Gaipl, U. S., Franz, S., Voll, R. E., Sheriff, A., Kalden, J. R., & i, M. H. (2004) · Current Rheumatology Reports · doi:10.1007/s11926-004-0016-1 · Cited by 36 · see citing works

Nephritogenic-antinephritogenic antibody network in lupus glomerulonephritis

Doria, A., & Gatto, M. (2012) · Lupus · doi:10.1177/0961203312462267 · Cited by 35 · see citing works

A plasma nucleosome releasing factor (NRF) with serine protease activity is instrumental in removal of nucleosomes from secondary necrotic cells

Zeerleder, S. S., Zwart, B., Velthuis, H. T., Manoe, R., Bulder, I., Rensink, I., & Aarden, L. A. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.10.037 · Cited by 35 · see citing works

DNase γ, DNase I and caspase‐activated DNase cooperate to degrade dead cells

Koyama, R., Arai, T., Kijima, M., Sato, S., Miura, S., Yuasa, M., Kitamura, D., & Mizuta, R. (2016) · Genes to Cells · doi:10.1111/gtc.12433 · Cited by 35 · see citing works

Role of Bacterial and Host DNases on Host-Pathogen Interaction during Streptococcus suis Meningitis

Meurer, M., Öhlmann, S., Bonilla, M. C., Valentin‐Weigand, P., Beineke, A., Hennig‐Pauka, I., Schwerk, C., Schroten, H., Baums, C. G., von Köckritz‐Blickwede, M., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155289 · Cited by 34 · see citing works

Removal of dying cells and systemic lupus erythematosus

Grossmayer, G. E., Munoz, L. E., Gaipl, U. S., Franz, S., Sheriff, A., Voll, R. E., Kalden, J. R., & i, M. H. (2005) · Modern Rheumatology · doi:10.1007/s10165-005-0430-x · Cited by 34 · see citing works

Cell-Free DNA in the Pathogenesis and Therapy of Non-Infectious Inflammations and Tumors

Műzes, G., Barta, B. B., Szabó, O., Horgas, V., & Sípos, F. (2022) · Biomedicines · doi:10.3390/biomedicines10112853 · Cited by 34 · see citing works

Involvement of lysosomal cathepsins in the cleavage of DNA topoisomerase I during necrotic cell death

Pacheco, F. J., Servin, J. A., Dang, D., Kim, J., Molinaro, C. A., Daniels‐Wells, T. R., Brown‐Bryan, T. A., Egami, M. I., & Casiano, C. A. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21147 · Cited by 32 · see citing works

The role of nuclear factors as “Find-Me”/alarmin signals and immunostimulation in defective efferocytosis and related disorders

Tajbakhsh, A., Rezaee, M., Barreto, G. E., Moallem, S. A., Henney, N. C., & Sahebkar, A. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2019.106134 · Cited by 30 · see citing works

Extracellular nucleic acids in immunity and cardiovascular responses: between alert and disease

Preissner, K. T., & Herwald, H. (2017) · Thrombosis and Haemostasis · doi:10.1160/th-16-11-0858 · Cited by 30 · see citing works

Reduced expression of C1q-mRNA in monocytes from patients with systemic lupus erythematosus

Moosig, F., Damm, F., Knorr-Spahr, A., Ritgen, M., Zeuner, R. A., Kneba, M., Ernst, M., & Schröder, J. O. (2006) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2006.03225.x · Cited by 29 · see citing works

Serum-dependent processing of late apoptotic cells for enhanced efferocytosis

Liang, Y. Y., Arnold, T., Michlmayr, A., Rainprecht, D., Perticevic, B., Spittler, A., & Oehler, R. (2014) · Cell Death and Disease · doi:10.1038/cddis.2014.210 · Cited by 27 · see citing works

Impaired degradation and aberrant phagocytosis of necrotic cell debris in the peripheral blood of patients with primary Sjögren's syndrome

Fragoulis, G. E., Vakrakou, A. G., Papadopoulou, A., Germenis, A. E., Kanavakis, E., Moutsopoulos, H. Μ., & Manoussakis, M. N. (2014) · Journal of Autoimmunity · doi:10.1016/j.jaut.2014.08.004 · Cited by 24 · see citing works

Towards a pro-resolving concept in systemic lupus erythematosus

Boeltz, S., Hagen, M., Knopf, J., Mahajan, A., Schick, M., Zhao, Y., Erfurt-Berge, C. S., Rech, J., Munoz, L. E., & i, M. H. (2019) · Seminars in Immunopathology · doi:10.1007/s00281-019-00760-5 · Cited by 24 · see citing works

Neutrophil extracellular traps generation and degradation in patients with granulomatosis with polyangiitis and systemic lupus erythematosus

Pruchniak, M. P., Ostafin, M., Wachowska, M., Jakubaszek, M. P., Kwiatkowska, B., Olesińska, M., Życińska, K., & Demkow, U. A. (2019) · Autoimmunity · doi:10.1080/08916934.2019.1631812 · Cited by 23 · see citing works

DNase1 activity in systemic lupus erythematosus patients with and without nephropathy

Martínez‐Valle, F., Balada, E., Ordi‐Ros, J., Buján-Rivas, S., Sellas, A., & Vilardell, M. (2009) · Rheumatology International · doi:10.1007/s00296-009-1199-6 · Cited by 23 · see citing works

Immunology of Apoptosis and Necrosis

Proskuryakov, S. Y., Gabai, V. L., Konoplyannikov, A. G., Александровна, З. И., & Kolesnikova, A. I. (2005) · Biochemistry (Moscow) · doi:10.1007/s10541-005-0263-4 · Cited by 22 · see citing works

Deoxyribonuclease 1-Mediated Clearance of Circulating Chromatin Prevents From Immune Cell Activation and Pro-inflammatory Cytokine Production, a Phenomenon Amplified by Low Trap1 Activity: Consequences for Systemic Lupus Erythematosus

Felux, J., Erbacher, A., Breckler, M., Hervé, R., Lemeiter, D., Mannherz, H. G., Napirei, M., Rammensee, H., & Decker, P. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.613597 · Cited by 20 · see citing works

Role of Mitochondria in the Chronification of Inflammation: Focus on Dysfunctional Mitophagy and Mitochondrial DNA Mutations

Orekhov, A. N., Summerhill, V. I., Khotina, V. A., Popov, M. A., Uzokov, J., & Sukhorukov, V. N. (2023) · Gene Expression · doi:10.14218/ge.2023.00061 · Cited by 19 · see citing works

Emerging cell-free DNA scavenging biomaterials for inflammatory diseases: From mechanisms to therapies

Xie, L., Lu, C., Wu, H., Zha, Z., Wang, H., & Miao, Z. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.07.051 · Cited by 18 · see citing works

Novel therapeutics for systemic lupus erythematosus

Wiesendanger, M., Stanevsky, A., Kovsky, S., & Diamond, B. (2006) · Current Opinion in Rheumatology · doi:10.1097/01.bor.0000218941.04613.85 · Cited by 16 · see citing works

The danger model in deciphering autoimmunity

Tveita, A. A. (2010) · Lara D. Veeken · doi:10.1093/rheumatology/keq004 · Cited by 16 · see citing works

Elevated levels of endogenous apoptotic DNA and IFN‐α in complement C4‐deficient mice: Implications for induction of systemic lupus erythematosus

Finke, D., Randers, K., Hoerster, R., Hennig, H., Zawatzky, R., Marion, T. N., Brockmann, C., Klempt‐Giessing, K., Jacobsen, K., Kirchner, H., et al. (2007) · European Journal of Immunology · doi:10.1002/eji.200636719 · Cited by 15 · see citing works

Cell free DNA biology and its involvement in breast carcinogenesis.

Delmonico, L., Alves, G., & Bines, J. (2020) · Advances in Clinical Chemistry · doi:10.1016/bs.acc.2019.12.006 · Cited by 12 · see citing works

Serum-dependent processing of late apoptotic cells and their immunogenicity

Liang, Y. Y., Rainprecht, D., Eichmair, E., Meßner, B., & Oehler, R. (2015) · APOPTOSIS · doi:10.1007/s10495-015-1163-8 · Cited by 10 · see citing works

Eine unzureichende Erkennung und Beseitigung von sterbenden Zellen kann zur Entstehung von chronischer Autoimmunität führen

Munoz, L. E., i, M. H., & Gaipl, U. S. (2005) · Zeitschrift für Rheumatologie · doi:10.1007/s00393-005-0769-6 · Cited by 10 · see citing works

Effects of exogenous deoxyribonuclease I in collagen antibody-induced arthritis

Macáková, K., Borbélyová, V., Tekeľová, M., Janko, J., Pastorek, M., Hokša, R., Moravanský, N., Šteňová, E., Vlková, B., & Celec, P. (2024) · Journal of Inflammation · doi:10.1186/s12950-024-00403-z · Cited by 8 · see citing works

Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes

Zhdanov, D. D., Plyasova, A. A., Pokrovsky, V. S., Pokrovskaya, M. V., Alexandrova, S. S., Gladilina, Y. A., & Sokolov, N. N. (2020) · Biochimie · doi:10.1016/j.biochi.2020.04.009 · Cited by 8 · see citing works

Prevalence and clinical significance of anti-C1q antibodies in cutaneous and systemic lupus erythematosus

Hegazy, A., Barakat, A. F., Gayyar, M. A. E., & Arafa, L. F. (2012) · Egyptian Journal of Medical Human Genetics · doi:10.1016/j.ejmhg.2012.01.006 · Cited by 8 · see citing works

Anti C1q antibodies in cutaneous lupus erythematosus.

Balanescu, A., Tanasescu, C., Balanescu, P. C., Olteanu, R., Badea, C. G., Petruţescu, B., Grancea, C., Vagu, C. D., Bleoţu, C., Ruță, S. M., et al. (2010) · PubMed · Cited by 7 · see citing works

Stripping cell-free DNA from its immune complex is essential for inflammation control using DNase I

Chen, S., Du, Y., Zhu, C., Li, C., Liu, L., Liu, L., & Chen, Y. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.123992 · Cited by 6 · see citing works

Effect of SARS-CoV-2 Infection and COVID-19 Vaccination on Oxidative Status of Human Placenta: A Preliminary Study

Macáková, K., Pšenková, P., Šupčíková, N., Vlková, B., Celec, P., & Záhumenský, J. (2023) · Antioxidants · doi:10.3390/antiox12071403 · Cited by 6 · see citing works

Molecules Involved in Recognition and Clearance of Apoptotic/Necrotic Cells and Cell Debris

Napirei, M., & Mannherz, H. G. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9293-0_4 · Cited by 5 · see citing works

The role of apoptosis and removal of apoptotic cells in the genesis of systemic lupus erythematosus

Fransen, J. H., Hilbrands, L. B., Koeter, C. M., & van der Vlag, J. (2009) · Cited by 4 · see citing works

Apo material as a trigger for inflammation in systemic lupus erythematosus

Meesmann, H. M., Parčina, M., Lorenz, H., Blank, N., & Schiller, M. R. (2009) · Autoimmunity · doi:10.1080/08916930902827819 · Cited by 4 · see citing works

No littering: The clearance of dead cells and leaking cellular contents and possible pathological complications

Brauner, J., Grosse‐Holz, F. M., Schett, G. A., i, M. H., & Munoz, L. E. (2013) · OA Arthritis · doi:10.13172/2052-9554-1-2-717 · Cited by 3 · see citing works

Cellular interactions and signalling defects in lupus (1)

Zouali, M., & Mageed, R. (2008) · Lupus · doi:10.1177/0961203307088247 · Cited by 2 · see citing works

Chromatin breakdown during necrosis by serum Dnase1 and the plasminogen system

Napirei, M., Wulf, S., & Mannherz, H. G. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20267 · Cited by 134 · see citing works

Role of C1q and DNase I in the control of autoimmunity towards nucleosomes in systemic lupus erythematosus

Erbacher, A. (2009)

Cooperation of Factor VII–Activating Protease and Serum DNase I in the Release of Nucleosomes From Necrotic Cells

Stephan, F., Marsman, G., Bakker, L. M., Bulder, I., Stavenuiter, F., Aarden, L. A., & Zeerleder, S. S. (2013) · Arthritis & Rheumatology · doi:10.1002/art.38265 · Cited by 50 · see citing works

Defects in the disposal of dying cells lead to autoimmunity

Gaipl, U. S., Franz, S., Voll, R. E., Sheriff, A., Kalden, J. R., & i, M. H. (2004) · Current Rheumatology Reports · doi:10.1007/s11926-004-0016-1 · Cited by 36 · see citing works

Lupus, DNase and defective disposal of cellular debris

Walport, M. J. (2000) · Nature Genetics · doi:10.1038/75963 · Cited by 146 · see citing works