CoChat
Sign Up
Cited by 2,002Colorectal Cancer Screening and DetectionGlobal Cancer Incidence and ScreeningColorectal Cancer Surgical Treatments

Annual report to the nation on the status of cancer, 1975‐2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates

Open access
Edwards, Brenda K., Ward, Elizabeth, Kohler, Betsy A., Eheman, Christie, Zauber, Ann G., Anderson, Robert N., Jemal, Ahmedin, Schymura, Maria J. +5 more·2010·Cancer
DOI 10.1002/cncr.24760PMC PMC3619726
Open this paper in CoChat — free account

Abstract

BACKGROUND.: The American Cancer Society, the Centers for Disease Control and Prevention (CDC), the National Cancer Institute (NCI), and the North American Association of Central Cancer Registries (NAACCR) collaborate annually to provide updated information regarding cancer occurrence and trends in the United States. This year's report includes trends in colorectal cancer (CRC) incidence and death rates and highlights the use of microsimulation modeling as a tool for interpreting past trends and projecting future trends to assist in cancer control planning and policy decisions. METHODS.: Information regarding invasive cancers was obtained from the NCI, CDC, and NAACCR; and information on deaths was obtained from the CDC's National Center for Health Statistics. Annual percentage changes in the age‐standardized incidence and death rates (based on the year 2000 US population standard) for all cancers combined and for the top 15 cancers were estimated by joinpoint analysis of long‐term trends (1975‐2006) and for short‐term fixed‐interval trends (1997‐2006). All statistical tests were 2‐sided. RESULTS.: Both incidence and death rates from all cancers combined significantly declined ( P < .05) in the most recent time period for men and women overall and for most racial and ethnic populations. These decreases were driven largely by declines in both incidence and death rates for the 3 most common cancers in men (ie, lung and prostate cancers and CRC) and for 2 of the 3 leading cancers in women (ie, breast cancer and CRC). The long‐term trends for lung cancer mortality in women had smaller and smaller increases until 2003, when there was a change to a nonsignificant decline. Microsimulation modeling demonstrates that declines in CRC death rates are consistent with a relatively large contribution from screening and with a smaller but demonstrable impact of risk factor reductions and improved treatments. These declines are projected to continue if risk factor modification, screening, and treatment remain at current rates, but they could be accelerated further with favorable trends in risk factors and higher utilization of screening and optimal treatment. CONCLUSIONS.: Although the decrease in overall cancer incidence and death rates is encouraging, rising incidence and mortality for some cancers are of concern. Cancer 2010. © 2009 American Cancer Society.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1002/cncr.24760

Cites

158 of 158 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The declines in colorectal cancer incidence in many high-incidence countries over the last decades have been considered the result of population-level shifts toward a healthier lifestyle and the introduction of screening.

    “The declines in colorectal cancer incidence in many high-incidence countries over the last decades have been considered the result of population-level shifts toward a healthier lifestyle (e.g., increased access to sources of fiber, such as fruits and vegetables) and the introduction of screening, 63,70”

    From Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. (2024) · cites this paper as [70]

    The Results section (page unavailable) attributes the U.S. colorectal cancer incidence decline from 1975 to 2000 to changes in risk factors and screening. The Discussion (page unavailable) notes that rates have stabilized or declined in economically developed countries, but it does not establish those causes across many countries or identify increased access to fiber-rich foods as a cause of the declines. (LLM, conf=0.86)

    Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 7

  1. [1]Wingo PA Ries LA Rosenberg HM Miller DS Edwards BK Cancer incidence and mortality, 1973–1995: a report card for the U.S Cancer 3 15 1998 82 6 1197 1207 9506368
  2. [11]Ries LA Wingo PA Miller DS The annual report to the nation on the status of cancer, 1973–1997, with a special section on colorectal cancer Cancer 5 15 2000 88 10 2398 2424 10820364
  3. [18]Manual of the international statistical classification of diseases, injuries, and causes of death, based on the recommendations of the ninth revision conference, 1975 Geneva, Switzerland World Health Organization 1977
  4. [27]Clegg LX Hankey BF Tiwari R Feuer EJ Edwards BK Estimating average annual percent change in trend analysis Statistics in Medicine 2009 PMC2843083 19856324
  5. [67]Jemal A Siegel R Ward E Hao Y Xu J Thun MJ Cancer statistics CA Cancer J Clin Jul-Aug 2009 59 4 225 249 19474385
  6. [128]Becker TM DKE Lawson H Saraiya M Jim M Waxman A Regional differences in cervical cancer incidence among American Indians and Alaska Natives, 1999–2004 Cancer 2008 In press 18720379
  7. [136]CDC CDC Weight of the Nation Conference Available from: http://www.cdc.gov/media/transcripts/2009/t090727.htm accessed August 19, 2009

Cited by

Sorted by citations

Related

Authors
Edwards, B. K., Ward, E., Kohler, B. A., Eheman, C., Zauber, A. G., Anderson, R. N., Jemal, A., Schymura, M. J., Lansdorp‐Vogelaar, I., Seeff, L. C., van Ballegooijen, M., Goede, S. L., & Ries, L. A. G.
Affiliations
  • National Institutes of Health (US)
  • American Cancer Society (US)
  • North American Association of Central Cancer Registries (US)
  • Centers for Disease Control and Prevention (US)
  • Memorial Sloan Kettering Cancer Center (US)
  • Erasmus MC (NL)
  • National Cancer Institute (US)
Corresponding author
Edwards, Brenda K.
ORCID
Venue
Cancer
Publisher
Wiley
Published
2009-12-07
Volume
116
Issue
3
Pages
544-573
ISSN
  • 0008-543X (ISSN-L)
  • 1097-0142
DOI
10.1002/cncr.24760
PMC
PMC3619726
OpenAlex
W2089300758
Cited by
2,002
References
158
Citations by year
2026: 37 · 2025: 52 · 2024: 73 · 2023: 92 · 2022: 112 · 2021: 115 · 2020: 125 · 2019: 128 · 2018: 136 · 2017: 115 · 2016: 134 · 2015: 167 · 2014: 157 · 2013: 149 · 2012: 187
FWCI
68.06
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Cancer (publishedVersion)
  • PubMed (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • Lincoln (University of Nebraska) (submittedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
  • RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
  • RePub (Erasmus University Rotterdam) (submittedVersion)
Funders
  • National Institutes of Health (Z99 CA999999)
  • National Cancer Institute (Y99 CA999999, P30CA008748)
Topics
  • Health Sciences › Medicine › Oncology › Colorectal Cancer Screening and Detection
  • Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
  • Health Sciences › Medicine › Oncology › Colorectal Cancer Surgical Treatments
Keywords
cancer incidence trends, cancer mortality trends, colorectal cancer, lung cancer, prostate cancer, breast cancer, cancer screening, cancer risk factors, cancer therapy, microsimulation, cancer control planning, racial and ethnic disparities, age-standardized rates
MeSH terms
Aged, Computer Simulation, Female, Humans, Male, Middle Aged, Mortality, Neoplasms, Registries, Risk Factors, Time Factors, United States, Colorectal Neoplasms, Incidence, Early Diagnosis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review