Yoga and meditation for menopausal symptoms in breast cancer survivors—a randomized controlled trial
Abstract
BACKGROUND: Breast cancer survivors have only very limited treatment options for menopausal symptoms. The objective of this trial was to evaluate the effects of a 12-week traditional Hatha yoga and meditation intervention on menopausal symptoms in breast cancer survivors. METHODS: Patients were randomly assigned either to a 12-week yoga and meditation intervention or to usual care. The primary outcome measure was total menopausal symptoms (Menopause Rating Scale [MRS] total score). Secondary outcome measures included MRS subscales, quality of life (Functional Assessment of Cancer Therapy-Breast), fatigue (Functional Assessment of Chronic Illness Therapy-Fatigue), depression, and anxiety (Hospital Anxiety and Depression Scale). Outcomes were assessed at week 12 and week 24 after randomization. RESULTS: In total, 40 women (mean age ± standard deviation, 49.2 ± 5.9 years) were randomized to yoga (n = 19) or to usual care (n = 21). Women in the yoga group reported significantly lower total menopausal symptoms compared with the usual care group at week 12 (mean difference, -5.6; 95% confidence interval, -9.2 to -1.9; P = .004) and at week 24 (mean difference, -4.5; 95% confidence interval, -8.3 to -0.7; P = .023). At week 12, the yoga group reported less somatovegetative, psychological, and urogenital menopausal symptoms; less fatigue; and improved quality of life (all P < .05). At week 24, all effects persisted except for psychological menopausal symptoms. Short-term effects on menopausal symptoms remained significant when only women who were receiving antiestrogen medication (n = 36) were analyzed. Six minor adverse events occurred in each group. CONCLUSIONS: Yoga combined with meditation can be considered a safe and effective complementary intervention for menopausal symptoms in breast cancer survivors. The effects seem to persist for at least 3 months.
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Mindful yoga and meditation led to significantly more improvement in depression than control (Cramer et al. 2015).
“Mindful yoga and meditation led to significantly more improvement in depression and quality of life than control.”
From The effectiveness of psychosocial interventions on non-physiological symptoms of menopause: A systematic review and meta-analysis (2024) · cites this paper as Cramer et al. (2015)
Mindful yoga and meditation led to significantly more improvement in quality of life than control (Cramer et al. 2015).
“Mindful yoga and meditation led to significantly more improvement in depression and quality of life than control.”
From The effectiveness of psychosocial interventions on non-physiological symptoms of menopause: A systematic review and meta-analysis (2024) · cites this paper as Cramer et al. (2015)
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- Authors
- Cramer, H., Rabsilber, S., Lauche, R., Kümmel, S., & Dobos, G.
- Affiliations
- University of Technology Sydney (AU)
- Malteser Krankenhaus St. Anna (DE)
- Kliniken Essen-Mitte (DE)
- Corresponding author
- Cramer, Holger
- Venue
- Cancer
- Publisher
- Wiley
- Published
- 2015-03-04
- Volume
- 121
- Issue
- 13
- Pages
- 2175-2184
- ISSN
- 0008-543X (ISSN-L)
- 1097-0142
- OpenAlex
- W1488819801
- Cited by
- 131
- References
- 54
- Citations by year
- 2026: 13 · 2025: 13 · 2024: 19 · 2023: 9 · 2022: 9 · 2021: 15 · 2020: 10 · 2019: 15 · 2018: 12 · 2017: 9 · 2016: 5 · 2015: 1 · 2014: 1
- FWCI
- 3.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cancer (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Keywords
- hatha yoga, meditation, menopausal symptoms, breast cancer survivors, complementary therapy, quality of life, fatigue, depression, anxiety, antiestrogen therapy, Menopause Rating Scale
- MeSH terms
- Breast Neoplasms, Female, Humans, Menopause, Middle Aged, Quality of Life, Yoga, Treatment Outcome, Survivors, Meditation
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