Yoga for symptom management in oncology: a review of the evidence base and future directions for research
Open accessAbstract
Because yoga is increasingly recognized as a complementary approach to cancer symptom management, patients/survivors and providers need to understand its potential benefits and limitations both during and after treatment. The authors reviewed randomized controlled trials (RCTs) of yoga conducted at these points in the cancer continuum (N = 29; n = 13 during treatment, n = 12 post‐treatment, and n = 4 with mixed samples). Findings both during and after treatment demonstrated the efficacy of yoga to improve overall quality of life (QOL), with improvement in subdomains of QOL varying across studies. Fatigue was the most commonly measured outcome, and most RCTs conducted during or after cancer treatment reported improvements in fatigue. Results also suggested that yoga can improve stress/distress during treatment and post‐treatment disturbances in sleep and cognition. Several RCTs provided evidence that yoga may improve biomarkers of stress, inflammation, and immune function. Outcomes with limited or mixed findings (eg, anxiety, depression, pain, cancer‐specific symptoms, such as lymphedema) and positive psychological outcomes (such as benefit‐finding and life satisfaction) warrant further study. Important future directions for yoga research in oncology include: enrolling participants with cancer types other than breast, standardizing self‐report assessments, increasing the use of active control groups and objective measures, and addressing the heterogeneity of yoga interventions, which vary in type, key components (movement, meditation, breathing), dose, and delivery mode.
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A review of 29 RCTs based on cancer patients' stage of treatment reported significant improvements for pain, sleep measured via actigraphy, biomarkers, and distress during cancer treatment, as well as significant improvements in self-reported cancer-related side effects and sleep following treatment.
“In another review of yoga outcomes based on cancer patients' stage of treatment (29 RCTs, including n = 13 undergoing treatment, n = 12 post-treatment, and n = 4 mixed samples; Danhauer et al. 2019), significant improvements were reported for pain, sleep measured via actigraphy, biomarkers (e.g., inflammation, cortisol), and distress during cancer treatment, as well as significant improvements in”
From Psychosocial and Integrative Oncology: Interventions Across the Disease Trajectory. (2023) · cites this paper as Danhauer et al. 2019
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Experimental — accuracy not yet measuredThere has historically been incomplete reporting of compliance to prescribed FITT programs in published studies.
“there has historically been incomplete reporting of compliance to a prescribed FITT program in published studies, likely because tracking and quantifying compliance can be burdensome (74–76).”
From Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable (2019) · cites this paper as [74]
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“However, trials are emerging of yoga for participants with other types of cancers, including ovarian, prostate, colorectal, brain, and blood cancers and advanced lung cancer, and the findings may be different for a more heterogeneous group of cancer survivors.(69,75-77,82,83) Another inherent challenge is that most st…”
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Sleep moderates the effects of Tibetan yoga for women with breast cancer undergoing chemotherapy
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Effect of yoga as a complementary therapy in prostate cancer survivors: a systematic review
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The Use of Yoga in Clinical Practice: A Descriptive Study
Adams, E. V., Crowe, B. M., Vanadore, J., Puymbroeck, M. V., & Schmid, A. A. (2022) · OBM Integrative and Complementary Medicine · doi:10.21926/obm.icm.2202020 · Cited by 3 · see citing works
Momeni, M., Khatooni, M., Alizadeh, A., & Mohebbi, S. (2025) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-025-04981-0 · Cited by 2 · see citing works
Jiang, L., Liu, R., Tan, X., Wang, F., & Sun, L. (2025) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2025.101567 · Cited by 3 · see citing works
Quality of life after breast cancer: Assessment, relevance and effective interventions
Schmidt, M. E., & Steindorf, K. (2020) · Senologie - Zeitschrift für Mammadiagnostik und -therapie · doi:10.1055/a-1030-9792 · Cited by 2 · see citing works
McDowell, I. (2023) · Springer eBooks · doi:10.1007/978-3-031-28986-6_8 · Cited by 3 · see citing works
Brunet, J., Hussien, J., Pitman, A., Wurz, A. J., Conte, E., Polskaia, N., & Seely, D. (2024) · Integrative Cancer Therapies · doi:10.1177/15347354241233517 · Cited by 2 · see citing works
Giridharan, S., Soumian, S., & Ansari, J. (2024) · Cureus · doi:10.7759/cureus.71857 · Cited by 2 · see citing works
Gonzalez, M., Grant, S. J., de Manincor, M., Lacey, J., & Sarris, J. J. (2022) · EXPLORE · doi:10.1016/j.explore.2022.10.003 · Cited by 2 · see citing works
Enhancing Access to Yoga for Older Male Veterans After Cancer: Examining Beliefs About Yoga
Auguste, E. J. (2021) · Federal Practitioner · doi:10.12788/fp.0180 · Cited by 2 · see citing works
KANSER TEDAVİSİ ALAN ÇOCUKLARDA YOGA TERAPİ: SİSTEMATİK DERLEME
Özdemir, B., & Gerçeker, G. Ö. (2022) · Sağlık Bilimleri Dergisi · doi:10.34108/eujhs.872346 · Cited by 1 · see citing works
- Authors
- Danhauer, S. C., Addington, E. L., Cohen, L., Sohl, S. J., Van Puymbroeck, M., Albinati, N. K., & Culos‐Reed, S. N.
- Affiliations
- Wake Forest University Health Sciences (US)
- Northwestern University (US)
- The University of Texas MD Anderson Cancer Center (US)
- School of Health Research, College of Behavioral, Social, and Health Sciences, Department of Parks, Recreation, and Tourism Management Clemson University Clemson South Carolina
- University of Calgary (CA)
- Faculty of Kinesiology University of Calgary Calgary Alberta Canada
- Corresponding author
- Danhauer, Suzanne C.
- ORCID
- Venue
- Cancer
- Publisher
- Wiley
- Published
- 2019-04
- Volume
- 125
- Issue
- 12
- Pages
- 1979-1989
- ISSN
- 0008-543X (ISSN-L)
- 1097-0142
- PMC
- PMC6541520
- OpenAlex
- W2932171133
- Cited by
- 174
- References
- 80
- Citations by year
- 2026: 22 · 2025: 13 · 2024: 29 · 2023: 21 · 2022: 25 · 2021: 26 · 2020: 22 · 2019: 16
- FWCI
- 2.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Cancer (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Center for Complementary and Integrative Health (K01AT008219)
- National Cancer Institute (CA193193)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Keywords
- yoga, cancer symptom management, quality of life, cancer-related fatigue, sleep disorders, cognitive function, inflammatory markers, immune function, complementary therapy, cancer survivors, breast cancer, meditation, benefit finding, life satisfaction
- MeSH terms
- Cancer Survivors, Humans, Neoplasms, Prognosis, Quality of Life, Yoga, Disease Management
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