Cited by 40Artificial Intelligence in Healthcare and EducationAI in cancer detectionRadiomics and Machine Learning in Medical Imaging

Artificial intelligence across the cancer care continuum

Open access
Riaz, Irbaz Bin, Khan, Muhammad Ali, Osterman, Travis J.·2025·Cancer

Abstract

Artificial intelligence (AI) holds significant potential to enhance various aspects of oncology, spanning the cancer care continuum. This review provides an overview of current and emerging AI applications, from risk assessment and early detection to treatment and supportive care. AI‐driven tools are being developed to integrate diverse data sources, including multi‐omics and electronic health records, to improve cancer risk stratification and personalize prevention strategies. In screening and diagnosis, AI algorithms show promise in augmenting the accuracy and efficiency of medical image analysis and histopathology interpretation. AI also offers opportunities to refine treatment planning, optimize radiation therapy, and personalize systemic therapy selection. Furthermore, AI is explored for its potential to improve survivorship care by tailoring interventions and to enhance end‐of‐life care through improved symptom management and prognostic modeling. Beyond care delivery, AI augments clinical workflows, streamlines the dissemination of up‐to‐date evidence, and captures critical patient‐reported outcomes for clinical decision support and outcomes assessment. However, the successful integration of AI into clinical practice requires addressing key challenges, including rigorous validation of algorithms, ensuring data privacy and security, and mitigating potential biases. Effective implementation necessitates interdisciplinary collaboration and comprehensive education for health care professionals. The synergistic interaction between AI and clinical expertise is crucial for realizing the potential of AI to contribute to personalized and effective cancer care. This review highlights the current state of AI in oncology and underscores the importance of responsible development and implementation.

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  • Generative AI systems can summarize studies, identify key themes, and surface relevant literature more efficiently than manual review.

    “Generative AI (GenAI) systems can summarize studies, identify key themes, and surface relevant literature more efficiently than manual review.8,9”

    From Artificial Intelligence in Oncology: Practical Applications Across Clinical Care, Scholarship, and Translation. (2026) · cites this paper as [8]

    The Evidence Generation and Synthesis section says LLMs can search literature, screen relevant citations, and extract data, while streamlining tasks that are time-consuming when done manually. The Care Delivery section describes evidence distillation and summarization of clinical narratives. These passages support finding relevant literature and improving efficiency, but do not specifically establish that the systems summarize studies or identify key themes across them. (LLM, conf=0.82)

    Experimental — accuracy not yet measured

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Authors
Riaz, I. B., Khan, M. A., & Osterman, T. J.
Affiliations
  • Mayo Clinic (US)
  • Vanderbilt University Medical Center (US)
Corresponding author
Osterman, Travis J.
Venue
Cancer
Publisher
Wiley
Published
2025-08-14
Volume
131
Issue
16
Pages
e70050-e70050
ISSN
  • 0008-543X (ISSN-L)
  • 1097-0142
OpenAlex
W4413116454
Cited by
40
References
119
Citations by year
2026: 32 · 2025: 8
FWCI
2.36
Type
journal article
Language
en
Open access
Locations
  • Cancer (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
National Cancer Institute (1R21CA274545‐01, P30 CA068485)
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiomics and Machine Learning in Medical Imaging
Keywords
artificial intelligence in oncology, cancer care continuum, cancer risk stratification, early cancer detection, medical image analysis, histopathology interpretation, radiation therapy optimization, survivorship care, end-of-life care, symptom management, prognostic model, clinical decision support, multi-omics integration, electronic health records, algorithm validation, data privacy and security, algorithmic bias, clinical workflow integration, patient-reported outcomes
MeSH terms
Artificial Intelligence, Continuity of Patient Care, Humans, Medical Oncology, Neoplasms, Risk Assessment, Precision Medicine

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