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Cited by 42

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Cell autonomous sorting and surface positioning in the formation of primitive endoderm in embryoid bodies

Rula, Malgorzata E., Cai, Kathy Q., Moore, Robert, Yang, Dong‐Hua, Staub, Cory M., Capo‐chichi, Callinice D., Jablonski, Sandra A., Howe, Philip H., Smith, Elizabeth R., Xu, Xiang‐Xi·2007·genesis
DOI 10.1002/dvg.20298
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Abstract

The differentiation and formation of the primitive endoderm in early embryos can be mimicked in vitro by the aggregation of embryonic stem cells to form embryoid bodies. We present morphological evidence that primitive endoderm cells often first locate in the interior of embryoid bodies and subsequently migrate to the surface. Cell mixing experiments indicate that surface positioning is an intrinsic property of endoderm epithelial cells. Moreover, Disabled‐2 (Dab2) is required for surface sorting and positioning of the endoderm cells: when Dab2 expression was eliminated, the differentiated endoderm epithelial cells distributed throughout the interior of the embryoid bodies. Surprisingly, E‐cadherin is dispensable for primitive endoderm differentiation and surface sorting in embryoid bodies. These results support the model that primitive endoderm cells first emerge in the interior of the inner cell mass and are subsequently sorted to the surface to form the primitive endoderm. genesis 45: 327–338, 2007. Published 2007 Wiley‐Liss, Inc.

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Crossref · 10.1002/dvg.20298

Cites

3 of 3 references verified0 citation errors · 0 not checkable

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This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Dab2 is critical for surface targeting and restriction of cell adhesion molecules and the establishment and maintenance of epithelial polarity.

    “Analyses in embryoid bodies and cultured cells support that Dab2 is critical for the surface targeting and restriction of cell adhesion molecules and the establishment and maintenance of epithelial polarity”

    From Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice (2016) · cites this paper as Rula et al., 2007

  • Dab2 functions in endocytic trafficking to sustain cell polarity and epithelial organization; loss of Dab2 leads to endoderm epithelial disorganization and embryonic failure.

    “Therefore, Dab2 functions in endocytic trafficking to sustain cell polarity and thus epithelial organization, and hence loss of Dab2 leads to endoderm epithelial disorganization and failure of the embryos”

    From Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice (2016) · cites this paper as Rula et al., 2007

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 40

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Metadata

Authors
Rula, M. E., Cai, K. Q., Moore, R., Yang, D., Staub, C. M., Capo‐chichi, C. D., Jablonski, S. A., Howe, P. H., Smith, E. R., & Xu, X.
Venue
genesis
Publisher
Wiley
Published
2007-06
Volume
45
Issue
6
Pages
327-338
ISSN
  • 1526-954X
  • 1526-968X
DOI
10.1002/dvg.20298
Cited by
42
References
3
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

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