JNK1 but not JNK2 promotes the development of steatohepatitis in mice

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2. Berberine Ameliorates Hepatic Steatosis and Suppresses Liver and Adipose Tissue Inflammation in Mice with Diet-induced Obesity
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3. Endoplasmic Reticulum Stress and the Unfolded Protein Response
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4. Mitochondrial DNA–enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity
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5. Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model
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6. Pathogenesis of NASH: Animal Models
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7. Obesity depresses the anti‐inflammatory HSP 70 pathway, contributing to NAFLD progression
   Fábio Cangeri Di Naso, Rossana Rosa Porto, Henrique Sarubbi Fillmann, Lucas Maggioni, Alexandre Vontobel Padoin, Rafael Jacques Ramos, Cláudio Corá Mottin, Aline Bittencourt, Norma Possa Marroni, Paulo Ivo Homem de Bittencourt · 2014 · Obesity
8. Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection
   Virginia Pardo, Águeda González‐Rodríguez, Jordi Muntané, Sara C. Kozma, Ángela M. Valverde · 2015 · Food and Chemical Toxicology
9. Endoplasmic Reticulum Stress and the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease
   Christopher L. Gentile, Melinda A. Frye, Michael J. Pagliassotti · 2010 · Antioxidants and Redox Signaling
10. Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling
    Jörn Markus Schattenberg, Mark J. Czaja · 2014 · Redox Biology
11. Lycium barbarum polysaccharides protect rat liver from non-alcoholic steatohepatitis-induced injury
    Jia Xiao, Eleanore C. Liong, Y P Ching, Raymond Chuen‐Chung Chang, Man‐Lung Fung, Aimin Xu, Kwok‐Fai So, George Lim Tipoe · 2013 · Nutrition and Diabetes
12. RETRACTED ARTICLE: Apoptosis and insulin resistance in liver and peripheral tissues of morbidly obese patients is associated with different stages of non-alcoholic fatty liver disease
    Duarte M. S. Ferreira, Rui Eduardo Castro, Mariana Verdelho Machado, Teresinha Evangelista, Ana Rita Silvestre, A. Costa, José Ricardo Hildebrandt Coutinho, Fátima Carepa, Helena Cortez‐Pinto, Cecília M. P. Rodrigues · 2011 · Diabetologia · Retracted
13. Chemoprevention of nonalcoholic fatty liver disease by dietary natural compounds
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14. Inhibition of lncRNA HULC improves hepatic fibrosis and hepatocyte apoptosis by inhibiting the MAPK signaling pathway in rats with nonalcoholic fatty liver disease
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15. Antiapoptotic Effect of c-Jun N-terminal Kinase-1 through Mcl-1 Stabilization in TNF-Induced Hepatocyte Apoptosis
    Yuzo Kodama, Kojiro Taura, Kouichi Miura, Bernd Schnabl, Yosuke Osawa, David A. Brenner · 2009 · Gastroenterology
16. Pathophysiological underpinnings of metabolic dysfunction-associated steatotic liver disease
    Mohammad Shafi Kuchay, Narendra Singh Choudhary, Bruno Ramos‐Molina · 2025 · American Journal of Physiology-Cell Physiology
17. Cellular stress in the pathogenesis of nonalcoholic steatohepatitis and liver fibrosis
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18. Intrahepatic insulin resistance in a murine model of steatohepatitis: effect of PPARγ agonist pioglitazone
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19. Peroxisome proliferator‐activated receptor‐α agonist, Wy 14 643, improves metabolic indices, steatosis and ballooning in diabetic mice with non‐alcoholic steatohepatitis
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20. Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis
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21. In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice
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22. Mitochondrial dysfunction in nonalcoholic steatohepatitis
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23. Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver
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24. Innate immune regulatory networks in hepatic lipid metabolism
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25. Inflammation in nonalcoholic steatohepatitis
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26. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK
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27. TLR9 is up-regulated in human and murine NASH: pivotal role in inflammatory recruitment and cell survival
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28. Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes
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29. Osteocalcin improves nonalcoholic fatty liver disease in mice through activation of Nrf2 and inhibition of JNK
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30. Liver-specific Inducible Nitric-oxide Synthase Expression Is Sufficient to Cause Hepatic Insulin Resistance and Mild Hyperglycemia in Mice
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31. Stress kinases in the modulation of metabolism and energy balance
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32. Genetically modified mouse models for the study of nonalcoholic fatty liver disease
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33. To die or not to die: death signaling in nonalcoholic fatty liver disease
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34. Systematic review on the treatment of pentoxifylline in patients with non-alcoholic fatty liver disease
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35. Evaluating causality of cellular senescence in non-alcoholic fatty liver disease
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36. The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one disease?
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37. Heme Oxygenase-1 Protects Against Steatohepatitis in Both Cultured Hepatocytes and Mice
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38. The activation of c-Jun NH2-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells
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39. Three-colour fluorescence immunohistochemistry reveals the diversity of cells staining for macrophage markers in murine spleen and liver
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40. c‐Jun N‐terminal kinase signaling in the pathogenesis of nonalcoholic fatty liver disease
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41. Anti-apoptotic and anti-inflammatory effects of Silybum marianum in treatment of experimental steatohepatitis
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42. SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high‐fat‐diet‐fed mice
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43. Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation
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44. Resolvin D1 reduces ER stress-induced apoptosis and triglyceride accumulation through JNK pathway in HepG2 cells
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45. Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis
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46. Activation of peroxisome proliferator‐activated receptor α by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation
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48. CYP2E1 Sensitizes the Liver to LPS- and TNFα-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases
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49. Hepatic free fatty acids accumulate in experimental steatohepatitis: Role of adaptive pathways
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50. Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury
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57. Ubiquitin‐Specific Protease 4 Is an Endogenous Negative Regulator of Metabolic Dysfunctions in Nonalcoholic Fatty Liver Disease in Mice
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58. Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation in high-fat-diet induced mice
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59. Chlorogenic acid alleviates autophagy and insulin resistance by suppressing JNK pathway in a rat model of nonalcoholic fatty liver disease
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60. Eicosapentaenoic Acid Improves Hepatic Metabolism and Reduces Inflammation Independent of Obesity in High-Fat-Fed Mice and in HepG2 Cells
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63. Adipokines and Redox Signaling: Impact on Fatty Liver Disease
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64. Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis
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67. Stress Signaling in the Methionine-Choline–Deficient Model of Murine Fatty Liver Disease
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69. Gene Expression Patterns in Hepatic Tissue and Visceral Adipose Tissue of Patients with Non-Alcoholic Fatty Liver Disease
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71. Baicalin attenuates diet induced nonalcoholic steatohepatitis by inhibiting inflammation and oxidative stress via suppressing JNK signaling pathways
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74. CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction
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79. Diabetic liver injury from streptozotocin is regulated through the caspase-8 homolog cFLIP involving activation of JNK2 and intrahepatic immunocompetent cells
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80. Tumor necrosis factor receptor-associated factor 5 (Traf5) acts as an essential negative regulator of hepatic steatosis
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81. An inhibitor of c-Jun NH2-terminal kinase, SP600125, protects mice from d-galactosamine/lipopolysaccharide-induced hepatic failure by modulating BH3-only proteins
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82. Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1 inhibition
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84. Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis
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85. Adenosine A2a receptor stimulation prevents hepatocyte lipotoxicity and non-alcoholic steatohepatitis (NASH) in rats
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86. Tissue Factor-Deficiency and Protease Activated Receptor-1-Deficiency Reduce Inflammation Elicited by Diet-Induced Steatohepatitis in Mice
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88. Non alcoholic steatohepatitis a precursor for hepatocellular carcinoma development
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91. Role of C-Jun N-terminal Kinase in Hepatocellular Carcinoma Development
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92. PNPLA3 I148M mediates the regulatory effect of NF‐kB on inflammation in PA‐treated HepG2 cells
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94. Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice
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95. Asking the Right Questions With Animal Models: Methionine- and Choline-Deficient Model in Predicting Adverse Drug Reactions in Human NASH
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96. Exercise retards hepatocarcinogenesis in obese mice independently of weight control
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97. Stress kinases in the development of liver steatosis and hepatocellular carcinoma
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98. New Insights from Rodent Models of Fatty Liver Disease
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99. Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis
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