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The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
Open accessAbstract
Peroxisome proliferators are a diverse group of chemicals, including several hypolipidaemic drugs, that activate a nuclear hormone receptor termed the peroxisome proliferator activated receptor (PPAR). The peroxisomal enzyme acyl CoA oxidase (ACO) is the most widely used marker of peroxisome proliferator action. We have examined the 5' flanking region of the rat ACO gene for sequences that mediate the transcriptional effect of peroxisome proliferators and have identified an element located 570 bp upstream of the ACO gene that confers responsiveness to the hypolipidaemic peroxisome proliferator Wy-14,643. This peroxisome proliferator response element (PPRE) contains a direct repeat of the sequence motifs TGACCT and TGTCCT and binds PPAR. These data therefore indicate an important role of PPAR in mediating the action of peroxisome proliferators including the induction of ACO.
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“PPAR␥ heterodimerizes with RXRs (Tugwood et al., 1992), and, during ligand activation, the PPAR/RXR heterodimer recruits coactivators and binds to sequence-specific PPAR response elements present in the promoter region of several target genes.”
From PPARγ/RXRα-Induced and CD36-Mediated Microglial Amyloid-β Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice (2012) · cites this paper as Tugwood et al., 1992
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In the citing paper
“PPAR␥ heterodimerizes with RXRs (Tugwood et al., 1992), and, during ligand activation, the PPAR/RXR heterodimer recruits coactivators and binds to sequence-specific PPAR response elements present in the promoter region of several target genes.”
From PPARγ/RXRα-Induced and CD36-Mediated Microglial Amyloid-β Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice (2012) · cites this paper as Tugwood et al., 1992
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Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
The Steroid and Thyroid Hormone Receptor Superfamily
Evans, R. M. (1988) · Science · doi:10.1126/science.3283939 · Cited by 7,394
HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS
Berry, M. N., & Friend, D. S. (1969) · The Journal of Cell Biology · doi:10.1083/jcb.43.3.506 · Cited by 4,407
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
Issemann, I., & Green, S. (1990) · Nature · doi:10.1038/347645a0 · Cited by 3,519
Self-citationUmesono, K., Murakami, K. K., Thompson, C. C., & Evans, R. M. (1991) · Cell · doi:10.1016/0092-8674(91)90020-y · Cited by 1,688
Lazarow, P. B., & de Duve, C. (1976) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.73.6.2043 · Cited by 1,044
Nuclear receptors enhance our understanding of transcription regulation
Green, S., & Chambon, P. (1988) · Trends in Genetics · doi:10.1016/0168-9525(88)90108-4 · Cited by 1,042
Self-citationIdentification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene
de Thé, H., Vivanco, M. D., Tiollais, P., Stunnenberg, H. G., & Dejean, A. (1990) · Nature · doi:10.1038/343177a0 · Cited by 991
Reddy, J. K., Lalvvai, N. D., & Farber, E. (1983) · Critical Reviews in Toxicology · doi:10.3109/10408448309029317 · Cited by 879
Steroid Receptor Family: Structure and Functions
Carson, M. A., Schrader, W. T., & O’Malley, B. W. (1990) · Endocrine Reviews · doi:10.1210/edrv-11-2-201 · Cited by 813
Research works printed but not linked: 4
- Lazarow,P.B. and de Duve,C. (1976) Proc. Natl. Acad. Sci. USA, 73, 2043-2046.
- Reddy,J.K. Goel,S.K., Nemali,M.R., Carrino,J.J., Laffler,T.G., Reddy,M.K., Sperbeck,S.J., Osumi,T., Hashimoto,T., Lalwani,N.D. and Rao,M.S. (1986) Proc. Natl. Acad. Sci. USA, 83, 1747-1751.
- Ausubel,F.M., Brent,R., Kingston,R.E., Moore,D.D., Seidman,J.G., Smith,J.A. and Struhl,K. (eds) (1990) Current Protocols in Molecular Biology. Wiley, New York.
- Green,S. (1991) Biochem. Pharmacol., in press.
Cited by
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Items 701–800 of 898
Sato, H., Ishikawa, M., Sugai, H., Funaki, A., Kimura, Y., Sumitomo, M., & Ueno, K. (2014) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2014-0026 · Cited by 12
Micronized Fenofibrate in Dyslipidemia
Sharpe, M., Ormrod, D. J., & Jarvis, B. (2002) · American Journal of Cardiovascular Drugs · doi:10.2165/00129784-200202020-00006 · Cited by 13
Kim, H. J., Woo, I. S., Kang, E. S., Eun, S. Y., Kim, G. H., Ham, S. A., Kim, H. J., Lee, J. H., Chang, K. C., Kim, J., et al. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.08.085 · Cited by 12
Leaver, M. J., & George, S. G. (1996) · Marine Environmental Research · doi:10.1016/0141-1136(95)00080-1 · Cited by 12
Ye, X., Lu, L., & Gill, S. S. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.7529 · Cited by 12
Pacot, C., Charmoillaux, M., Goudonnet, H., Truchot, R., & Latruffe, N. (1993) · Biochemical Pharmacology · doi:10.1016/0006-2952(93)90043-v · Cited by 12
Radioautographic Study on the Intracellular Localization of Bezafibrate in Cultured Rat Hepatocytes.
Momose, Y., Naito, J., SUZAWA, H., Kanzawa, M., & Nagata, T. (1995) · ACTA HISTOCHEMICA ET CYTOCHEMICA · doi:10.1267/ahc.28.61 · Cited by 11
Ham, S. A., Lee, H., Hwang, J. S., Kang, E. S., Yoo, T., Paek, K. S., Tae, J., Park, C., Oh, J., Kim, J., et al. (2014) · Journal of Vascular Research · doi:10.1159/000365250 · Cited by 11
tert-Butylhydroquinone reduces lipid accumulation in C57BL/6 mice with lower body weight gain
Nam, K., Kim, Y. H., Kwon, H. J., Rhee, S., Kim, W.-J., & Han, M. (2013) · Archives of Pharmacal Research · doi:10.1007/s12272-013-0109-3 · Cited by 11
Caira, F., Pacot, C., Bardot, O., Cherkaoui‐Malki, M., & Latruffe, N. (1995) · Biochemical Pharmacology · doi:10.1016/0006-2952(94)00480-a · Cited by 11
Towards the Management of Inflammation: Recent Developments of mPGES-1 Inhibitors
Dallaporta, M., Pecchi, É., Thirion, S., Jean, A., & Troadec, J. (2009) · Recent Patents on CNS Drug Discovery · doi:10.2174/157488910789753549 · Cited by 11
Lipid‐activated nuclear receptors: from gene transcription to the control of cellular metabolism
Crestani, M., Mitro, N., & Fabiani, E. D. (2004) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.200300936 · Cited by 11
Ding, S., Li, Y., Nestor, K., Velleman, S. G., & Mersmann, H. J. (2003) · Poultry Science · doi:10.1093/ps/82.1.17 · Cited by 11
Heinlein, C. A., & Chang, C. (2003) · Endocrine · doi:10.1385/endo:21:2:139 · Cited by 11
Garberg, P., & Thullberg, M. (1996) · Chemico-Biological Interactions · doi:10.1016/0009-2797(95)03667-9 · Cited by 11
Genome Science of Lipid Metabolism and Obesity
Takahashi, N., Goto, T., Hirai, S., Uemura, T., & Kawada, T. (2009) · Forum of nutrition/Bibliotheca Nutritio et dieta · doi:10.1159/000212736 · Cited by 10
Yamashita, M. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.10.032 · Cited by 10
Lipid accumulation mediated by adiponectin in C2C12 myogenesis
Yin, C., Long, Q., Lei, T., Chen, X., Long, H., Feng, B., Peng, Y., Wu, Y., & Yang, Z. (2009) · BMB Reports · doi:10.5483/bmbrep.2009.42.10.667 · Cited by 9
Cellular responses to excess fatty acids
Kim, H., & Ye, J. (2013) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000048 · Cited by 10
Lee, M. J., Gee, P., & Beard, S. E. (1997) · PubMed · Cited by 10
Molecular analysis of peroxisome proliferation in the hamster
Choudhury, A. I., Sims, H. M., Horley, N., Roberts, R. A., Tomlinson, S. R., Salter, A. M., Bruce, M., Shaw, P. N., Kendall, D. A., Barrett, D. A., et al. (2004) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2004.01.019 · Cited by 10
Molecular and genetic aspects of cardiac fatty acid homeostasis in health and disease
Windt, L. J. D. (2002) · European Heart Journal · doi:10.1053/euhj.2001.2979 · Cited by 10
Perturbation of the Mitosis/Apoptosis Balance: A Fundamental Mechanism in Toxicology
Roberts, R. A., Nebert, D. W., Hickman, J. A., Richburg, J. H., & Goldsworthy, T. L. (1997) · Toxicological Sciences · doi:10.1093/toxsci/38.2.107 · Cited by 10
Winrow, C. J., Kassam, A., Miyata, K., Marcus, S. L., HUNTER, J., Capone, J. P., & Rachubinski, R. A. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb18618.x · Cited by 10
Sun, J. H., Li, H., Luo, X., Lu, R., & Ji, H. (2020) · Fish Physiology and Biochemistry · doi:10.1007/s10695-020-00816-6 · Cited by 9
Rangel-Torres, B. E., García-Montoya, I. A., Rodríguez‐Tadeo, A., & Jiménez-Vega, F. (2022) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-022-10012-y · Cited by 9
Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-α
Martinsen, T. C., Bakke, I., Chen, D., Sandvik, A. K., Zahlsen, K., Aamo, T. O., & Waldum, H. L. (2005) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00268.2005 · Cited by 9
Effects of Δ12‐prostaglandin J2 on bone regeneration and growth factor expression in rats
Damrongsri, D., Geva, S., Salvi, G. E., Cooper, L. F., Limwongse, V., & Offenbacher, S. (2005) · Clinical Oral Implants Research · doi:10.1111/j.1600-0501.2005.01181.x · Cited by 9
Brétillon, L., Alexson, S. E. H., Joffre, F., Pasquis, B., & Sébédio, J. (2003) · Lipids · doi:10.1007/s11745-003-1149-y · Cited by 9
PPARα stimulates the rat gastrin-producing cell
Bakke, I., Hammer, T. A., Sandvik, A. K., & Waldum, H. L. (2002) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(02)00187-9 · Cited by 9
Impact of dietary protein content on uncoupling protein mRNA abundance in swine
Ramsay, T. G., & Mitchell, A. D. (2007) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2007.11.007 · Cited by 9
Kanbe, E., Abe, A., Towatari, M., Kawabe, T., Saito, H., & Emi, N. (2003) · Experimental Hematology · doi:10.1016/s0301-472x(03)00003-1 · Cited by 9
An Updated Review of its Clinical Efficacy in the Management of Dyslipidaemia
Drury, P., Franceschini, G., Malík, J., Melenovský, V., & Pasceri, V. (2002) · Cited by 9
Analysis of Peroxisome Proliferator–responsive Enhancer of the Rat Acyl‐CoA Oxidase Genea
Osumi, T., Osada, S., & Tsukamoto, T. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb18617.x · Cited by 9
Ahn, M. Y., Ham, S. A., Yoo, T., Lee, W. J., Hwang, J. S., Paek, K. S., Lim, D., Han, S. G., Lee, C.-H., & Seo, H. G. (2018) · Journal of Vascular Research · doi:10.1159/000486570 · Cited by 8
Tissue-Specific 5′ Heterogeneity of PPARα Transcripts and Their Differential Regulation by Leptin
Garratt, E. S., Vickers, M. H., Gluckman, P. D., Hanson, M. A., Burdge, G. C., & Lillycrop, K. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067483 · Cited by 8
Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator
Steffensen, K. R., Bouzga, M. M., Skjeldal, F. M., Kasi, C., Karahasan, A., Matre, V., Bakke, O., Guérin, S. L., & Eskild, W. (2007) · BMC Molecular Biology · doi:10.1186/1471-2199-8-106 · Cited by 8
González, M. D. C., Corton, J. C., Acero, N., Mingarro, D. M., Quirós, Y., Álvarez‐Millán, J. J., Herrera, E., & Bocos, C. (2012) · PPAR Research · doi:10.1155/2012/483536 · Cited by 8
Gene Expression in Low Glycemic Index Diet – Impact on Metabolic Control
Takeda, E., Arai, H., Muto, K., Matsuo, K., Sakuma, M., Fukaya, M., Yamanaka‐Okumura, H., Yamamoto, H., & Taketani, Y. (2007) · Forum of nutrition/Bibliotheca Nutritio et dieta · doi:10.1159/000107089 · Cited by 8
Molavi, B., Rasouli, N., & Mehta, J. L. (2002) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/107424840200700i101 · Cited by 8
The Role of PPARα as a“lipostat” Transcription Factor
Djouadi, F., Weinheimer, C. J., & Kelly, D. P. (2006) · Kluwer Academic Publishers eBooks · doi:10.1007/0-306-46818-2_25 · Cited by 8
Singh, M. K., Yadav, R., Bhaskar, A. K., Sengupta, S., & Sachidanandan, C. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2022.159246 · Cited by 7
Mirisola, M. G. (2023) · Genes · doi:10.3390/genes14111997 · Cited by 8
Biermanns, M., & Gärtner, J. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3039 · Cited by 7
Suzuki, M., Nakamura, F., Taguchi, E., Nakata, M., Wada, F., Takihi, M., Inoue, T., Ohta, S., & Kawachi, H. (2018) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-018-3270-7 · Cited by 7
Lee, J., Lee, J., & Cho, Y. S. (2018) · Journal of Clinical Medicine · doi:10.3390/jcm7120488 · Cited by 7
Wu, J., Chu, E., Paul, B. A., & Kang, Y. (2022) · Cancers · doi:10.3390/cancers14215272 · Cited by 7
Banner, C. D., Rafter, J. J., & Gustafsson, J.-Α. (1996) · Springer eBooks · doi:10.1007/978-1-4612-2332-0_4 · Cited by 7
Dadras, S. S., Cook, W. S., Yeldandi, A. V., Wq, C., Rao, M. S. R., Wang, Z., & Reddy, J. K. (2001) · Gene Expression · doi:10.3727/000000001783992579 · Cited by 7
Bayly, A. C., Roberts, R. A., & Dive, C. (1997) · Advances in molecular and cell biology · doi:10.1016/s1569-2558(08)60275-1 · Cited by 7
Lewis, D. F. V., & Lake, B. G. (1997) · Toxicology in Vitro · doi:10.1016/s0887-2333(96)00067-7 · Cited by 7
Nuclear Receptors and Female Reproduction: A Tale of 3 Scientists, Jensen, Gustafsson, and O’Malley
Chaudhuri, G. (2008) · Reproductive Sciences · doi:10.1177/1933719108314516 · Cited by 7
Giddings, S. J., Clarke, S. E., & Gibson, G. G. (1997) · European Journal of Drug Metabolism and Pharmacokinetics · doi:10.1007/bf03190963 · Cited by 7
Pacot, C., & Latruffe, N. (1993) · Biochimie · doi:10.1016/0300-9084(93)90082-4 · Cited by 7
Peroxisome Proliferators: Response
Melnick, R. L. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.109-a463 · Cited by 7
Scott, D. K., Hall, R. K., & Granner, D. K. (1995) · Biochemical Journal · doi:10.1042/bj3100483 · Cited by 7
Liu, J., Yu, B., Mao, X., Huang, Z., Zheng, P., Yu, J., He, J., & Chen, D. (2014) · The Journal of Animal and Plant Sciences · Cited by 6
Nagy, G., Dániel, B., Cuaranta‐Monroy, I., & Nagy, L. (2020) · Molecular and Cellular Biology · doi:10.1128/mcb.00547-19 · Cited by 6
Sabzevari, O., Hatcher, M., Kentish, P., O'Sullivan, M., & Gibson, G. G. (1996) · Toxicology · doi:10.1016/0300-483x(95)03150-e · Cited by 6
Waxman, D. J. (1996) · Advances in molecular and cell biology · doi:10.1016/s1569-2558(08)60349-5 · Cited by 6
Motoki, Y., Tamura, H., Watanabe, T., & Suga, T. (1999) · Cancer Letters · doi:10.1016/s0304-3835(98)00287-0 · Cited by 6
Clofibric acid down-regulation of metallothionein IIA in HepG2 human hepatoma cells
Bianchi, A., Bécuwe, P., Collet, P., Keller, J. M., Domenjoud, L., & Dauça, M. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(01)00863-2 · Cited by 6
Exposure to Peroxisome Proliferators: Reassessment of the Potential Carcinogenic Hazard
Roberts, R. A., Moffat, G., & Ashby, J. (2001) · Environmental Health Perspectives · doi:10.1289/ehp.109-a462 · Cited by 6
Marilley, D., Mahfoudi, A., & Wahli, W. (1994) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(94)90239-9 · Cited by 6
Hayashida, K., Kume, N., Minami, M., Inui-Hayashida, A., Mukai, E., Toyohara, M., & Kita, T. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.08.193 · Cited by 6
Farrants, A. Ö., Nilsson, A., Trøen, G., Blomhoff, R., & Pedersen, J. I. (1993) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(93)90272-b · Cited by 6
Hur, J., Kang, E. S., Hwang, J. S., Lee, W. J., Won, J. P., Lee, H. G., Kim, E., & Seo, H. G. (2021) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2021.08.003 · Cited by 5
Apolipoprotein AV: gene expression,physiological role in lipid metabolism and clinical relevance
Prieur, X., Huby, T., Rodríguez, J. C., Couvert, P., & Chapman, J. (2008) · Future Lipidology · doi:10.2217/17460875.3.4.371 · Cited by 5
González, M. D. C., Corton, J. C., Cattley, R. C., Herrera, E., & Bocos, C. (2009) · Biochimie · doi:10.1016/j.biochi.2009.05.007 · Cited by 5
Balogun, K. A., & Cheema, S. K. (2015) · Springer eBooks · doi:10.1007/978-3-319-15961-4_27 · Cited by 5
Isolation and Cloning of Human Peroxisome Proliferator Activated Receptor Gamma CDNA
Greene, M. E., Blumberg, B., Kwan, K. W., Hsieh, L., Greene, G. L., & Nimer, S. D. (1997) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-5325-0_37 · Cited by 5
Roberts, R. A., Goodman, J. I., Shertzer, H. G., Dalton, T. P., & Farland, W. H. (2003) · Toxicology Mechanisms and Methods · doi:10.1080/15376510309823 · Cited by 5
Amsaguine, S., Bianchi, A., Collet, P., Huin‐Schohn, C., Jeanvoine, A., Bécuwe, P., Krémarik, P., Domenjoud, L., Keller, J. M., Schohn, H., et al. (2003) · Microscopy Research and Technique · doi:10.1002/jemt.10328 · Cited by 5
Peroxisome biogenesis occurs in late dorsal‐anterior structures in the development of Xenopus laevis
Cooper, C. A., Walsh, L. A., & Damjanovski, S. (2007) · Developmental Dynamics · doi:10.1002/dvdy.21370 · Cited by 4
PPARs: Important Regulators in Metabolism and Inflammation
Sanderson, L. M., & Kersten, S. (2010) · Springer eBooks · doi:10.1007/978-90-481-3303-1_10 · Cited by 4
Park, B.-M., Yoon, O.-J., & Lee, D.-H. (2017) · Korean Journal of Clinical Laboratory Science · doi:10.15324/kjcls.2017.49.1.28 · Cited by 4
Pharmacological and Toxicological Advances in PPAR-Related Medicines
Kamijo, Y., Nicol, C. J. B., & Alexson, S. E. H. (2012) · PPAR Research · doi:10.1155/2012/940964 · Cited by 4
Kim, S., Hong, M., Song, K., Lee, H., Ryoo, S., & Heo, T.-H. (2014) · Biological Research · doi:10.1186/0717-6287-47-42 · Cited by 4
Tugwood, J. D., Aldridge, T. C., Lambe, K. G., Macdonald, N., & Woodyatt, N. J. (1998) · Archives of toxicology. Supplement · doi:10.1007/978-3-642-46856-8_33 · Cited by 4
Self-citationActivation of a peroxisome-proliferating catabolite of cholic acid to its CoA ester
Nishimaki‐Mogami, T., Takahashi, A., & Hayashi, Y. (1993) · Biochemical Journal · doi:10.1042/bj2960265 · Cited by 4
Peroxisome Proliferator–Activated Receptors and The Metabolic Syndrome
Meiliana, A., & Wijaya, A. (2009) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v1i1.79 · Cited by 4
Eacho, P. I., FOXWORTHY, P. S., Lawrence, J. W., Herron, D. K., & Noonan, D. J. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb18630.x · Cited by 4
Cohen, R. A. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000137187.16206.79 · Cited by 4
Rodriíguez, C., Noé, V., Cabrero, C., Ciudad, C. J., & Laguna, J. C. (2000) · Molecular Pharmacology · doi:10.1016/s0026-895x(24)12155-4 · Cited by 3
Hosseini, A., Salman, M., Zhou, Z., Drackley, J. K., Trevisi, E., & Loor, J. J. (2017) · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology · doi:10.1186/s40104-017-0196-y · Cited by 3
PPARα, A Key Regulator of Hepatic Energy Homeostasis in Health and Disease
Leuenberger, N., & Wahli, W. (2009) · Springer eBooks · doi:10.1007/978-3-642-00150-5_20 · Cited by 3
Carvalho, D. E. D., Citro, M., & Tibbles, A. C. (2008) · PubMed Central · Cited by 3
Karahashi, M., Fukuhara, H., Hoshina, M., Sakamoto, T., Yamazaki, T., Mitsumoto, A., Kawashima, Y., & Kudo, N. (2013) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b13-00631 · Cited by 3
Ramsay, T. G., Mitchell, A. D., & Richards, M. P. (2008) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2007.12.001 · Cited by 3
PPARs, RXRs, and Drug‐Metabolizing Enzymes
Hardwick, J. P., & Chiang, J. Y. L. (2009) · PPAR Research · doi:10.1155/2009/589626 · Cited by 4
Kang, K. (2014) · Korean Journal of Acupuncture · doi:10.14406/acu.2014.025 · Cited by 3
Nishida, T., Tsuneyama, K., Tago, Y., Nomura, K., Fujimoto, M., Nakajima, T., Noguchi, A., Minamisaka, T., Hatta, H., & Imura, J. (2021) · The Scientific World JOURNAL · doi:10.1155/2021/1583154 · Cited by 3
Receptor-Mediated Non-Genotoxic Carcinogenesis: New Models for Risk Assessment?
Green, S. (1991) · Human & Experimental Toxicology · doi:10.1177/096032719101000602 · Cited by 3
Self-citationAkter, M. H., Razzaque, A. M., Liu, Y., Fumoto, T., Motojima, K., Yamaguchi, T., Hirose, F., & Osumi, T. (2006) · PPAR Research · doi:10.1155/ppar/2006/71916 · Cited by 3
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Abadin, H. G., Ashizawa, A. E., Stevens, Y.-W., Llados, F., Diamond, G., Sage, G. W., Citra, M. J., Quinones, A., Bosch, S. J., & Swarts, S. G. (2007) · Cited by 3
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Metadata
- Authors
- Tugwood, J. D., Issemann, I., Anderson, R. G., Bundell, K. R., McPheat, W. L., & Green, S.
- Venue
- The EMBO Journal
- Published
- 1992-02-01
- Volume
- 11
- Issue
- 2
- Pages
- 433-439
- ISSN
- 0261-4189 (ISSN-L)
- 1460-2075
- PMC
- PMC556472
- OpenAlex
- W98247596
- Cited by
- 895
- References
- 33
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 8 · 2020: 9 · 2019: 7 · 2018: 16 · 2017: 8 · 2016: 14 · 2015: 12 · 2014: 24 · 2013: 27 · 2012: 16
- FWCI
- 20.01
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The EMBO Journal (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Peroxisome Proliferator-Activated Receptors
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nuclear Receptors and Signaling
- Keywords
- peroxisome proliferator-activated receptors, peroxisome proliferators, acyl-CoA oxidase, peroxisome proliferator response element, 5'-flanking region, transcriptional regulation, Wy-14,643, hypolipidaemic drugs
- MeSH terms
- Animals, Anticholesteremic Agents, Base Sequence, Binding Sites, Cell Line, Humans, Kinetics, Methylation, Microbodies, Molecular Sequence Data, Oligodeoxyribonucleotides, Oxidoreductases, Plasmids, Promoter Regions, Genetic, Pyrimidines, Repetitive Sequences, Nucleic Acid, Transfection, Chloramphenicol O-Acetyltransferase, Baculoviridae, Acyl-CoA Oxidase, Fatty Acid Desaturases, Rats
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