Bile Formation and Secretion

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

Gottesman, M. M., & PASTAN, I. (1993) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.62.070193.002125 · Cited by 3,569

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

Juliano, R. L., & Ling, V. W. T. (1976) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(76)90160-7 · Cited by 3,317

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

Thiebaut, F., Tsuruo, T., Hamada, H., Gottesman, M., Pastan, I., & Willingham, M. (1987) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.84.21.7735 · Cited by 2,823

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Schinkel, A. H., Smit, J., van Tellingen, O., Beijnen, J. H., Wagenaar, E., van Deemter, L., Mol, C. A. A. M., van der Valk, M. A., Robanus-Maandag, E. C., Riele, H. T., et al. (1994) · Cell · doi:10.1016/0092-8674(94)90212-7 · Cited by 2,284

The Enzymes, Regulation, and Genetics of Bile Acid Synthesis

Russell, D. W. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161712 · Cited by 2,069

BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER

Ambudkar, S. V., Dey, S., Hrycyna, C. A., Ramachandra, M., Pastan, I. H., & Gottesman, M. M. (1999) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.39.1.361 · Cited by 2,059

Membrane Fusion: Grappling with SNARE and SM Proteins

Südhof, T. C., & Rothman, J. E. (2009) · Science · doi:10.1126/science.1161748 · Cited by 2,027

The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene

Bull, P. C., Thomas, G. R., Rommens, J. M., Forbes, J., & Cox, D. W. (1993) · Nature Genetics · doi:10.1038/ng1293-327 · Cited by 1,939

Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis

Sinal, C. J., Tohkin, M., Miyata, M., Ward, J. M., Lambert, G., & Gonzalez, F. J. (2000) · Cell · doi:10.1016/s0092-8674(00)00062-3 · Cited by 1,819

Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption

Altmann, S. W., Davis, H. R., Zhu, L.-J., Yao, X., Hoos, L. M., Tetzloff, G. G., Iyer, S. P. N., Maguire, M., Golovko, A., Zeng, M., et al. (2004) · Science · doi:10.1126/science.1093131 · Cited by 1,818

Liquid-crystal organization of liver tissue

Morales-Navarrete, H. A., Nonaka, H., Scholich, A., Segovia‐Miranda, F., de Back, W., Meyer, K., Bogorad, R. L., Koteliansky, V., Brusch, L., Kalaidzidis, Y. L., et al. (2019) · eLife · doi:10.7554/elife.44860 · Cited by 62

Hepatic fibrosis: Targeting peroxisome proliferator-activated receptor alpha from mechanism to medicines

Gong, L., Wei, F., Gonzalez, F. J., & Li, G. (2023) · Hepatology · doi:10.1097/hep.0000000000000182 · Cited by 61

Primary Biliary Cholangitis and Primary Sclerosing Cholangitis: Current Knowledge of Pathogenesis and Therapeutics

Park, J. W., Kim, J. H., Kim, S. E., Jung, J. H., Jang, M. K., Park, S. H., Lee, M. S., Kim, H. S., Suk, K. T., & Kim, D. J. (2022) · Biomedicines · doi:10.3390/biomedicines10061288 · Cited by 60

The Emerging Role of Viability Testing During Liver Machine Perfusion

Brüggenwirth, I. M. A., van Leeuwen, O. B., Porte, R. J., & Martins, P. N. A. (2021) · Liver Transplantation · doi:10.1002/lt.26092 · Cited by 58

Oral bioavailability of bioactive compounds; modulating factors, in vitro analysis methods, and enhancing strategies

Dima, C. V., Assadpour, E., Nechifor, A., Dima, Ş., Li, Y., & Jafari, S. M. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2023.2199861 · Cited by 58

Animal models of cholestasis: An update on inflammatory cholangiopathies

Mariotti, V., Cadamuro, M., Spirlı̀, C., Fiorotto, R., Strazzabosco, M., & Fabris, L. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.07.025 · Cited by 58

Fenofibrate Improves Liver Function and Reduces the Toxicity of the Bile Acid Pool in Patients With Primary Biliary Cholangitis and Primary Sclerosing Cholangitis Who Are Partial Responders to Ursodiol

Ghonem, N. S., Auclair, A. M., Hemme, C. L., Gallucci, G. M., de la Rosa Rodriguez, R., Boyer, J. L., & Assis, D. N. (2020) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1930 · Cited by 57

Homozygous p.Ser267Phe in SLC10A1 is associated with a new type of hypercholanemia and implications for personalized medicine

Liu, R., Chen, C., Xia, X., Liao, Q., Wang, Q., Newcombe, P. J., Xu, S., Chen, M., Ding, Y., Li, X., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-07012-2 · Cited by 57

Bile Composition as a Diagnostic and Prognostic Tool in Liver Transplantation

Brüggenwirth, I. M. A., Porte, R. J., & Martins, P. N. A. (2020) · Liver Transplantation · doi:10.1002/lt.25771 · Cited by 55

Blood‐Bile Barrier: Morphology, Regulation, and Pathophysiology

Pradhan-Sundd, T., & Monga, S. P. (2019) · Gene Expression · doi:10.3727/105221619x15469715711907 · Cited by 54

Bile acid metabolism in type 2 diabetes mellitus

Sandoval, M. C., & Haeusler, R. A. (2025) · Nature Reviews Endocrinology · doi:10.1038/s41574-024-01067-8 · Cited by 54

Reassessing immune control of hepatitis A virus

Walker, C. M., Feng, Z., & Lemon, S. M. (2015) · Current Opinion in Virology · doi:10.1016/j.coviro.2015.01.003 · Cited by 54

Zebrafish abcb11b mutant reveals strategies to restore bile excretion impaired by bile salt export pump deficiency

Ellis, J. L., Bove, K. E., Schuetz, E. G., Leino, D. G., Valencia, C. A., Schuetz, J. D., Miethke, A. G., & Yin, C. (2017) · Hepatology · doi:10.1002/hep.29632 · Cited by 54

Bile Acid Signaling in Inflammatory Bowel Disease

Bromke, M. A., & Krzystek‐Korpacka, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22169096 · Cited by 54

Clinical and molecular study of a pediatric patient with sodium taurocholate cotransporting polypeptide deficiency

Deng, M., Mao, M., Li, G., Chen, F., Wen, W., & Song, Y. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3752 · Cited by 54

Recent advances in understanding and managing cholestasis

Wagner, M., & Trauner, M. (2016) · F1000Research · doi:10.12688/f1000research.8012.1 · Cited by 53

Spexin Acts as Novel Regulator for Bile Acid Synthesis

Lin, C., Zhao, L., Huang, T., Lü, L., Khan, M., Liu, J., Zhong, L. L. D., Cai, Z., Fan, B., Wong, A., et al. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00378 · Cited by 53

A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation

Yuan, Z., Zhang, H., Hasnat, M., Ding, J., Chen, X., Liang, P., Sun, L., Zhang, L., & Jiang, Z. (2019) · Toxicology · doi:10.1016/j.tox.2019.01.005 · Cited by 53

Bacterial second messenger c-di-GMP: Emerging functions in stress resistance

Wang, Z., Li, S., Liu, X., Shen, X., & Li, X. (2023) · Microbiological Research · doi:10.1016/j.micres.2023.127302 · Cited by 52

Validation of a Simple and Robust Liebermann–Burchard Colorimetric Method for the Assay of Cholesterol in Selected Milk Products in Ghana

Adu, J. K., Amengor, C. D. K., Kabiri, N. C., Orman, E., Patamia, S. A. G., & Okrah, B. K. (2019) · International Journal of Food Science · doi:10.1155/2019/9045938 · Cited by 52

Multi-Omics Reveals That the Rumen Transcriptome, Microbiome, and Its Metabolome Co-regulate Cold Season Adaptability of Tibetan Sheep

Liu, X., Sha, Y., Lv, W., Cao, G., Guo, X., Pu, X., Wang, J., Li, S., Hu, J., & Luo, Y. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.859601 · Cited by 51

Coagulation in liver toxicity and disease: Role of hepatocyte tissue factor

Kopec, A. K., & Luyendyk, J. P. (2014) · Thrombosis Research · doi:10.1016/j.thromres.2014.03.023 · Cited by 50

Targeted pharmacotherapies for defective ABC transporters

Vauthier, V., Housset, C., & Falguières, T. (2017) · Biochemical Pharmacology · doi:10.1016/j.bcp.2017.02.020 · Cited by 50

Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid–Induced Injury

Ferrebee, C. B., Li, J., Haywood, J., Pachura, K. J., Robinson, B. S., Hinrichs, B. H., Jones, R. M., Rao, A., & Dawson, P. A. (2018) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2018.01.006 · Cited by 50

Probiotics for the treatment of hyperlipidemia: Focus on gut-liver axis and lipid metabolism

You, M. S., Zhou, L., Wu, F., Zhang, L., Zhu, S.-X., & Zhang, H. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107694 · Cited by 53

Bile Acids in Cholestasis and its Treatment

Arab, J. P., Cabrera, D., & Arrese, M. A. (2017) · Annals of Hepatology · doi:10.5604/01.3001.0010.5497 · Cited by 49

Regulatory mechanisms of the bile salt export pump (BSEP/ABCB11) and its role in related diseases

Ren, T., Pang, L., Dai, W., Wu, S., & Kong, J. (2021) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2021.101641 · Cited by 48

Cytotoxicity ofMoringaoleiferafruits on human liver cancer and molecular docking analysis of bioactive constituents against caspase‐3 enzyme

Siddiqui, S., Upadhyay, S., Ahmad, I., Hussain, A., & Ahamed, M. (2021) · Journal of Food Biochemistry · doi:10.1111/jfbc.13720 · Cited by 47

Role of Multidrug Resistance Protein 3 in Antifungal-Induced Cholestasis

Mahdi, Z., Synal-Hermanns, U., Yoker, A., Locher, K. P., & Stieger, B. (2016) · Molecular Pharmacology · doi:10.1124/mol.116.103390 · Cited by 47

Using Zebrafish to Model Liver Diseases-Where Do We Stand?

Pham, D.-H., Zhang, C., & Yin, C. (2017) · Current Pathobiology Reports · doi:10.1007/s40139-017-0141-y · Cited by 47

Pathobiology of biliary epithelia

Cheung, A., Pisarello, M. J. L., & LaRusso, N. F. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.06.024 · Cited by 47

Repopulating the biliary tree from the peribiliary glands

de Jong, I. E. M., van Leeuwen, O. B., Lisman, T., Gouw, A. S. H., & Porte, R. J. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.07.037 · Cited by 47

High fat diet for induced dyslipidemia and cardiac pathological alterations in Wistar rats compared to Sprague Dawley rats

Udomkasemsab, A., & Prangthip, P. (2018) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/j.arteri.2018.09.004 · Cited by 46

Recent advances in the ontogeny of drug disposition

Chapron, B. D., Chapron, A., & Leeder, J. S. (2021) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.14821 · Cited by 46

Primary Cilia and Calcium Signaling Interactions

Saternos, H. C., Ley, S. T., & AbouAlaiwi, W. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197109 · Cited by 46

Metabolome and microbiome analysis revealed the effect mechanism of different feeding modes on the meat quality of Black Tibetan sheep

Zhang, X., Han, L., Gui, L., Raza, S. H. A., Hou, S., Yang, B., Wang, Z., Ma, Y., Makhlof, R. T. M., Alhuwaymil, Z., et al. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1076675 · Cited by 46

Roles of Sphincter of Oddi Laxity in Bile Duct Microenvironment in Patients with Cholangiolithiasis: From the Perspective of the Microbiome and Metabolome

Liang, T., Su, W., Zhang, Q., Li, G., Gao, S., Lou, J., Zhang, Y., Ma, T., & Bai, X. (2015) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2015.12.009 · Cited by 45

Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse

Zhang, J., He, K., Cai, L., Chen, Y., Yang, Y., Shi, Q., Woolf, T. F., Ge, W., Guo, L., Borlak, J. T., et al. (2016) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2016.03.019 · Cited by 45

Comparative genomics of Lactobacillus salivarius strains focusing on their host adaptation

Lee, J.-Y., Han, G., Kim, E. B., & Choi, Y. (2017) · Microbiological Research · doi:10.1016/j.micres.2017.08.008 · Cited by 45

Cryo-EM structure of human bile salts exporter ABCB11

Wang, L., Hou, W., Chen, L., Jiang, Y., Xu, D., Sun, L., Zhou, C., & Chen, Y. (2020) · Cell Research · doi:10.1038/s41422-020-0302-0 · Cited by 45

Bile acid metabolism and FXR-mediated effects in human cholestatic liver disorders

Molinaro, A., & Marschall, H. (2022) · Biochemical Society Transactions · doi:10.1042/bst20210658 · Cited by 44

Roles of Ileal ASBT and OSTα-OSTβ in Regulating Bile Acid Signaling

Dawson, P. A. (2017) · Digestive Diseases · doi:10.1159/000450987 · Cited by 44

Immune system and cholangiocytes: A puzzling affair in primary biliary cholangitis

Ronca, V., Mancuso, C., Milani, C., Carbone, M., Oo, Y. H., & Invernizzi, P. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.5mr0320-200r · Cited by 45

TGR5 deficiency in excitatory neurons ameliorates Alzheimer’s pathology by regulating APP processing

Li, C., Wang, L., Xie, W., Chen, E., Chen, Y., Li, H., Can, D., Lei, A., Wang, Y., & Zhang, J. (2024) · Science Advances · doi:10.1126/sciadv.ado1855 · Cited by 46

Modulation of Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles

Zhang, B., Kuipers, F., de Boer, J. F., & Kuivenhoven, J. A. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm11010004 · Cited by 43

Solute carrier transporters: potential targets for digestive system neoplasms

Xie, J., Zhu, X. Y., Liu, L.-M., & Meng, Z. Q. (2018) · Cancer Management and Research · doi:10.2147/cmar.s152951 · Cited by 42

Role of Bile Acids and the Biliary HCO3− Umbrella in the Pathogenesis of Primary Biliary Cholangitis

van Niekerk, J., Kersten, R., & Beuers, U. H. (2018) · Clinics in Liver Disease · doi:10.1016/j.cld.2018.03.013 · Cited by 42

Metabolic regulation through the endosomal system

Gilleron, J., Gerdes, J. M., & Zeigerer, A. (2019) · Traffic · doi:10.1111/tra.12670 · Cited by 44

Mitigation of organophosphorus insecticides from environment: Residual detoxification by bioweapon catalytic scavengers

Paidi, M. K., Satapute, P., Haider, M. S., Udikeri, S. S., Lakshmikantha, R. Y., Vo, D. N., Govarthanan, M., & Jogaiah, S. (2021) · Environmental Research · doi:10.1016/j.envres.2021.111368 · Cited by 42

The Role of FGF19 and MALRD1 in Enterohepatic Bile Acid Signaling

Wang, L. X., Frey, M. R., & Kohli, R. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.799648 · Cited by 42

Bile acid and nonalcoholic steatohepatitis: Molecular insights and therapeutic targets

Cheng, Z., Chen, Y., Schnabl, B., Chu, H., & Yang, L. (2023) · Journal of Advanced Research · doi:10.1016/j.jare.2023.06.009 · Cited by 41

Inhibition of MDR3 Activity in Human Hepatocytes by Drugs Associated with Liver Injury

He, K., Cai, L., Shi, Q., Liu, H., & Woolf, T. F. (2015) · Chemical Research in Toxicology · doi:10.1021/acs.chemrestox.5b00201 · Cited by 41

Mouse models of gallstone disease

Wang, T. Y., Portincasa, P., Liu, M., Tso, P., & Wang, D. Q. ‐. (2017) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000417 · Cited by 41

Intravital Dynamic and Correlative Imaging of Mouse Livers Reveals Diffusion‐Dominated Canalicular and Flow‐Augmented Ductular Bile Flux

Vartak, N., Günther, G., Joly, F., Damle‐Vartak, A., Wibbelt, G., Fickel, J., Jörs, S., Begher‐Tibbe, B., Friebel, A., Wansing, K., et al. (2020) · Hepatology · doi:10.1002/hep.31422 · Cited by 41

The Accumulation and Molecular Effects of Trimethylamine N-Oxide on Metabolic Tissues: It’s Not All Bad

Krueger, E. S., Lloyd, T. S., & Tessem, J. S. (2021) · Nutrients · doi:10.3390/nu13082873 · Cited by 41

Ursodeoxycholic acid in pregnancy?

de Vries, E., & Beuers, U. (2019) · Journal of Hepatology · doi:10.1016/j.jhep.2019.08.020 · Cited by 40

Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro

Roos, F. J. M., Wu, H., Willemse, J., Lieshout, R., Albarinos, L. A. M., Kan, Y., Poley, J., Bruno, M. J., de Jonge, J., Bártfai, R., et al. (2021) · Clinical and Translational Medicine · doi:10.1002/ctm2.566 · Cited by 40

ATP Binding Cassette Transporters and Cancer: Revisiting Their Controversial Role

Sharma, P., Singh, N., & Sharma, S. (2021) · Pharmacogenomics · doi:10.2217/pgs-2021-0116 · Cited by 40

PPAR-Mediated Bile Acid Glucuronidation: Therapeutic Targets for the Treatment of Cholestatic Liver Diseases

Gallucci, G. M., Hayes, C. M., Boyer, J. L., Barbier, O., Assis, D. N., & Ghonem, N. S. (2024) · Cells · doi:10.3390/cells13151296 · Cited by 40

Biophysical Elucidation of Amyloid Fibrillation Inhibition and Prevention of Secondary Nucleation by Cholic Acid: An Unexplored Function of Cholic Acid

Majid, N., Siddiqi, M. K., Khan, A. N., Shabnam, S., Malik, S., Alam, A., Uversky, V. N., & Khan, R. H. (2019) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.9b00482 · Cited by 40

Multidimensional analysis of human intestinal fluid composition

Pyper, K., Brouwers, J., Augustijns, P., Khadra, I., Dunn, C., WILSON, C. G., & Halbert, G. (2020) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2020.06.011 · Cited by 40

Bile Acid Sequestrants for Hypercholesterolemia Treatment Using Sustainable Biopolymers: Recent Advances and Future Perspectives

Islam, M. S., Sharif, A., Kwan, N., & Tam, K. C. (2022) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.2c00007 · Cited by 40

Bile Acid Metabolism in Health and Disease

Li, T., & Chiang, J. Y. L. (2020) · Wiley eBooks · doi:10.1002/9781119436812.ch23 · Cited by 40

Diffusible Signal Factors Act through AraC-Type Transcriptional Regulators as Chemical Cues To Repress Virulence of Enteric Pathogens

Bosire, E. M., Eade, C. R., Schiltz, C. J., Reid, A. J., Troutman, J. M., Chappie, J. S., & Altier, C. (2020) · Infection and Immunity · doi:10.1128/iai.00226-20 · Cited by 39

Hepatic gene transfer of human aquaporin‐1 improves bile salt secretory failure in rats with estrogen‐induced cholestasis

Marrone, J., Soria, L. R., Danielli, M., Lehmann, G. L., Larocca, M. C., & Marinelli, R. A. (2016) · Hepatology · doi:10.1002/hep.28564 · Cited by 39

Pediatric Cholestatic Diseases: Common and Unique Pathogenic Mechanisms

Sutton, H., Karpen, S. J., & Kamath, B. M. (2024) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-031521-025623 · Cited by 39

Can a fibrotic liver afford epithelial-mesenchymal transition?

Munker, S., Wu, Y., Ding, H.-G., Liebe, R., & Weng, H. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i26.4661 · Cited by 38

Metabolomic Profiling of Portal Blood and Bile Reveals Metabolic Signatures of Primary Sclerosing Cholangitis

Tietz-Bogert, P. S., Kim, M., Cheung, A., Tabibian, J. H., Heimbach, J. K., Rosen, C. B. B., Nandakumar, M., Lazaridis, K. N., LaRusso, N. F., Sung, J., et al. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19103188 · Cited by 38

Hypothalamus-Pituitary-Adrenal Dysfunction in Cholestatic Liver Disease

Petrescu, A. D., Kain, J., Liere, V., Heavener, T. E., & DeMorrow, S. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00660 · Cited by 38

Comparisons of the Sexual Cycles for the Coccidian Parasites Eimeria and Toxoplasma

Genova, B. M. D., & Knoll, L. J. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.604897 · Cited by 38

Piezo1–Pannexin1 complex couples force detection to ATP secretion in cholangiocytes

Desplat, A., Penalba, V., Gros, E., Parpaite, T., Coste, B., & Delmas, P. (2021) · Journal of General Physiology · doi:10.1085/jgp.202112871 · Cited by 38

Crohn’s Disease, Host–Microbiota Interactions, and Immunonutrition: Dietary Strategies Targeting Gut Microbiome as Novel Therapeutic Approaches

Núñez‐Sánchez, M. Á., Melgar, S., O'DONOGHUE, K., Martínez‐Sánchez, M. A., Fernández-Ruiz, V. E., Ferrer‐Gómez, M., Ruiz‐Alcaraz, A. J., & Ramos‐Molina, B. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158361 · Cited by 38

Knockout of the primary sclerosing cholangitis‐risk gene Fut2 causes liver disease in mice

Maroni, L., Hohenester, S. D., van de Graaf, S. F. J., Tolenaars, D., van Lienden, K. P., Verheij, J., Marzioni, M., Karlsen, T. H., Elferink, R. P. J. O., & Beuers, U. H. (2017) · Hepatology · doi:10.1002/hep.29029 · Cited by 38

Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP

Liu, H., Irobalieva, R. N., Kowal, J., Ni, D., Nosol, K., Bang-Sørensen, R., Lancien, L., Stahlberg, H., Stieger, B., & Locher, K. P. (2023) · Nature Communications · doi:10.1038/s41467-023-43109-1 · Cited by 37

OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd‐EOB‐DTPA uptake and correlates with risk of malignancy

Sciarra, A., Schmidt, S., Pellegrinelli, A., Maggioni, M., Dondossola, D. E., Pasquier, J., Cigala, C., Tosi, D., Halkic, N., Bulfamante, G., et al. (2018) · Liver International · doi:10.1111/liv.13964 · Cited by 37

Hepatoprotective potential of standardized Ficus species in intrahepatic cholestasis rat model: Involvement of nuclear factor-κB, and Farnesoid X receptor signaling pathways

El‐Hawary, S. S., Ali, Z. Y., & Younis, I. Y. (2018) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2018.11.026 · Cited by 37

Predictor parameters of liver viability during porcine normothermic ex situ liver perfusion in a model of liver transplantation with marginal grafts

Linares, I., Echeverri, J. A., Cleland, S., Kaths, J. M., Rosales, R., Goto, T., Kollmann, D., Hamar, M., Urbanellis, P., Mazilescu, L., et al. (2019) · American Journal of Transplantation · doi:10.1111/ajt.15395 · Cited by 37

Bird Feces as Indicators of Metal Pollution: Pitfalls and Solutions

Eeva, T., Raivikko, N., Espín, S., Sánchez‐Virosta, P., Ruuskanen, S., Sorvari, J., & Rainio, M. J. (2020) · Toxics · doi:10.3390/toxics8040124 · Cited by 37

Bile multi‐omics analysis classifies lipid species and microbial peptides predictive of carcinoma of gallbladder

Sharma, N., Yadav, M. C., Tripathi, G., Mathew, B., Bindal, V., Falari, S., Pamecha, V., & Maras, J. S. (2022) · Hepatology · doi:10.1002/hep.32496 · Cited by 37

Site‐specific distribution of claudin‐based paracellular channels with roles in biological fluid flow and metabolism

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Bile acids regulate lipid metabolism through selective actions on fatty acid absorption

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