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Optical windows for head tissues in near‐infrared and short‐wave infrared regions: Approaching transcranial light applications
Abstract
Optical properties of the rat head tissues (brain cortex, cranial bone and scalp skin) are assessed, aiming at transcranial light applications such as optical imaging and phototherapy. The spectral measurements are carried out over the wide spectral range of 350 to 2800 nm, involving visible, near‐infrared (NIR) and short‐wave infrared (SWIR) regions. Four tissue transparency windows are considered: ~700 to 1000 nm (NIR‐I), ~1000 to 1350 nm (NIR‐II), ~1550 to 1870 nm (NIR‐III or SWIR) and ~2100 to 2300 nm (SWIR‐II). The values of attenuation coefficient and total attenuation length are determined for all windows and tissue types. The spectra indicate transmittance peaks in NIR, NIR‐II and SWIR‐II, with maximum tissue permeability for SWIR light. The use of SWIR‐II window for the transcranial light applications is substantiated. Furthermore, absorbance of the head tissues is investigated in details, by defining and describing the characteristic absorption peaks in NIR‐SWIR.
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“However, using ex-vivo rat tissue Golovynskyi et al., showed that NIR III has the potential to be optimal for imaging skin due to reduced water absorption in this region [29].”
From Relevance and utility of the in-vivo and ex-vivo optical properties of the skin reported in the literature: a review [Invited] (2023) · cites this paper as [29]
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Metadata
- Authors
- Golovynskyi, S., Golovynska, I., Stepanova, L. I., Datsenko, O. I., Liu, L., Qu, J., & Ohulchanskyy, T. Y.
- Affiliations
- Shenzhen University (CN)
- Taras Shevchenko National University of Kyiv (UA)
- Corresponding author
- Qu, Junle
- Ohulchanskyy, Tymish Y.
- ORCID
- Venue
- Journal of Biophotonics
- Publisher
- Wiley
- Published
- 2018-09-07
- Volume
- 11
- Issue
- 12
- Pages
- e201800141-e201800141
- ISSN
- 1864-063X (ISSN-L)
- 1864-0648
- OpenAlex
- W2887981390
- Cited by
- 209
- References
- 77
- Citations by year
- 2026: 17 · 2025: 32 · 2024: 34 · 2023: 27 · 2022: 36 · 2021: 29 · 2020: 20 · 2019: 14
- FWCI
- 10.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Biophotonics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (61525503, 61620106016, 81727804, 61722508)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Laser Applications in Dentistry and Medicine
- Keywords
- tissue optical properties, near-infrared, shortwave infrared, cerebral cortex, cranial bone, scalp skin, attenuation coefficient, absorption spectra, phototherapy, optical imaging
- MeSH terms
- Animals, Infrared Rays, Skull, Rats, Optical Phenomena, Absorption, Physicochemical
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