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Prevalence of low femoral bone density in older U.S. women from NHANES III

Looker, Anne C., Johnston, Conrad C., Wahner, Heinz W., Dunn, William L., Calvo, Mona S., Harris, Tamara B., Heyse, Stephen P., Lindsay, Robert L.·1995·Journal of Bone and Mineral Research

Abstract

Data on the number of U.S. women with low femoral bone mineral density (BMD) are currently available only from indirect estimates. We used dual-energy X-ray absorptiometry (DXA) measurements of femoral BMD from phase 1 of the third National Health and Nutrition Examination Survey (NHANES III, 1988–1991) to estimate prevalences of low femoral BMD in women ages 50 years and older using an approach proposed recently by an expert panel of the World Health Organization (WHO). Cutpoints for low BMD were derived from BMD data of 194 non-Hispanic white (NHW) women aged 20–29 years from the NHANES III dataset. The prevalence of older U.S. women with femoral osteopenia (BMD between 1 standard deviation [SD] and 2.5 SD below the mean of young NHW women) ranged from 34–50% in four different femur regions, which corresponds to ∼12–17 million women. The prevalence with osteoporosis (BMD >2.5 SD below the mean of young NHW women) ranged from 17–20%, or ∼6–7 million women. Prevalences were 1.3–2.4 times higher in NHW women than non-Hispanic black women (NHB), and 0.8–1.2 times higher in NHW versus Mexican American (MA) women. The estimated numbers of NHW, NHB, and MA women with osteopenia were 10–15 million, 800,000–1.2 million, and 300,000–400,000, respectively; corresponding figures for osteoporosis were 5–6 million, 200,000–300,000, and 100,000 respectively. Thus, the first data on BMD from a nationally representative sample of older women show a substantial number with low femoral BMD. The majority of these women are white, but the number of minority women with low BMD is not trivial.

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Metadata

Authors
Looker, A. C., Johnston, C. C., Wahner, H. W., Dunn, W. L., Calvo, M. S., Harris, T. B., Heyse, S. P., & Lindsay, R. L.
Venue
Journal of Bone and Mineral Research
Published
1995-05-01
Volume
10
Issue
5
Pages
796-802
ISSN
  • 0884-0431 (ISSN-L)
  • 1523-4681
OpenAlex
W1979344569
Cited by
1,379
References
45
FWCI
20.90
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Prevalence of low femoral bone density in older U.S. women from NHANES III. https://app.cochat.ai/papers/10.1002/jbmr.5650100517
The paper
Looker, A. C., Johnston, C. C., Wahner, H. W., Dunn, W. L., Calvo, M. S., Harris, T. B., Heyse, S. P., & Lindsay, R. L. (1995). Prevalence of low femoral bone density in older U.S. women from NHANES III. Journal of Bone and Mineral Research. https://doi.org/10.1002/jbmr.5650100517

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