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Cited by 407

The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.

Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus

Akash, Muhammad Sajid Hamid, Rehman, Kanwal, Chen, Shuqing·2013·Journal of Cellular Biochemistry
DOI 10.1002/jcb.24402
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Abstract

Type 2 diabetes mellitus (T2DM) is characterized by progressive β‐cell dysfunctioning and insulin resistance. This article reviews recent literature with special focus on inflammatory mechanisms that provoke the pathogenesis of T2DM. We have focused on the recent advances in progression of T2DM including various inflammatory mechanisms that might induce inflammation, insulin resistance, decrease insulin secretion from pancreatic islets and dysfunctioning of β‐cells. Here we have also summarized the role of various pro‐inflammatory mediators involved in inflammatory mechanisms, which may further alter the normal structure of β‐cells by inducing pancreatic islet's apoptosis. In conclusion, it is suggested that the role of inflammation in pathogenesis of T2DM is crucial and cannot be neglected. Moreover, the insight of inflammatory responses in T2DM may provide a new gateway for the better treatment of diabetes mellitus. J. Cell. Biochem. 114: 525–531, 2013. © 2012 Wiley Periodicals, Inc.

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Show all 24 references

Research works printed but not linked: 39

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Metadata

Authors
Akash, M. S. H., Rehman, K., & Chen, S.
Venue
Journal of Cellular Biochemistry
Publisher
Wiley
Published
2013-01-22
Volume
114
Issue
3
Pages
525-531
ISSN
  • 0730-2312 (ISSN-L)
  • 1097-4644
DOI
10.1002/jcb.24402
OpenAlex
W2026514466
Cited by
407
References
24
FWCI
21.95
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

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CoChat. (2026). Citation check: Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus. https://app.cochat.ai/papers/10.1002/jcb.24402
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Akash, M. S. H., Rehman, K., & Chen, S. (2013). Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus. Journal of Cellular Biochemistry. https://doi.org/10.1002/jcb.24402

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.