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Browning of White Fat: Novel Insight Into Factors, Mechanisms, and Therapeutics: FAT BROWNING AND THEIR POTENTIAL AS THERAPEUTICS
Open accessAbstract
What is more interesting about brown adipose tissue (BAT) is its ability to provide thermogenesis, protection against obesity by clearing triglycerides, releasing batokines, and mitigating insulin resistance. White adipose tissue (WAT) on the other hand stores excess energy and secretes some endocrine factors like leptin for regulating satiety. For the last decade there has been an increasing interest in the browning of fat keeping in view its beneficial effects on metabolic disorders and protection in the form of perivascular fat. Obesity is one such metabolic disorder that leads to significant morbidity and mortality from obesity-related disorders such as type 2 diabetes mellitus (T2D) and cardiovascular disease risk. Browning of white fat paves the way to restrict obesity and obesity related disorders. Although exercise has been the most common factor for fat browning; however, there are other factors that involve: (1) beta aminoisobutyric acid (BAIBA); (2) gamma amino butyric acid (GABA); (3) PPARɣ agonists; (4) JAK inhibition; and (5) IRISIN. In this review, we propose two novel factors musclin and TFAM for fat browning. Musclin a myokine released from muscles during exercise activates PPARɣ which induces browning of WAT that has beneficial metabolic and cardiac effects. TFAM is a transcription factor that induces mitochondrial biogenesis. Since BAT is rich in mitochondria, higher expression of TFAM in WAT or TFAM treatment in WAT cells can induce browning of WAT. We propose that fat browning can be used as a therapeutic tool for metabolic disorders and cardiovascular diseases. J. Cell. Physiol. 232: 61-68, 2017. © 2016 Wiley Periodicals, Inc.
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“Moreover, BAIBA has been proposed as a promising molecule capable of inducing the thermogenic framework by an independent pathway of adrenergic activation (Jeremic et al., 2017).”
From Physical Exercise-Induced Myokines and Muscle-Adipose Tissue Crosstalk: A Review of Current Knowledge and the Implications for Health and Metabolic Diseases (2018) · cites this paper as Jeremic et al., 2017
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“Targeting of brown adipose tissue and browning white adipose tissue (inducing white adipocytes to become beige adipocytes) may increase thermogenesis, lead to negative energy balance, and decrease glucose and triglyceride levels [181].”
From Anti-Obesity Medications and Investigational Agents: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022 (2022) · cites this paper as [181]
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Cites
Brown Adipose Tissue: Function and Physiological Significance
CANNON, B., & NEDERGAARD, J. (2004) · Physiological Reviews · doi:10.1152/physrev.00015.2003 · Cited by 6,433
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., Long, J. Z., et al. (2012) · Nature · doi:10.1038/nature10777 · Cited by 4,810
Identification and Importance of Brown Adipose Tissue in Adult Humans
Cypess, A. M., Lehman, S., Williams, G., Tal, I., Rodman, D., Goldfine, A. B., Kuo, F. C., Palmer, E. L., Tseng, Y.-H., Doria, A., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810780 · Cited by 4,399
Mechanisms of fatty acid-induced inhibition of glucose uptake.
Boden, G., Chen, X., Ruiz, J., White, J. V., & Rossetti, L. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117252 · Cited by 3,720
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
Berg, A. H., Combs, T. P., Du, X., Brownlee, M., & Scherer, P. E. (2001) · Nature Medicine · doi:10.1038/90992 · Cited by 2,526
Brown and beige fat: Development, function and therapeutic potential
Harms, M., & Seale, P. (2013) · Nature Medicine · doi:10.1038/nm.3361 · Cited by 2,328
Fruebis, J., Tsao, T., Javorschi, S., Ebbets-Reed, D., Erickson, M., Yen, F. T., Bihain, B. E., & Lodish, H. F. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.2005 · Cited by 2,007
Unexpected evidence for active brown adipose tissue in adult humans
Nedergaard, J., Bengtsson, T., & Cannon, B. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00691.2006 · Cited by 1,824
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
Fisher, F. M., Kleiner, S., Douris, N., Fox, E. C., Mepani, R. J., Verdeguer, F., Wu, J., Kharitonenkov, A., Flier, J. S., Maratos-Flier, E., et al. (2012) · Genes & Development · doi:10.1101/gad.177857.111 · Cited by 1,478 · cited 1×
“They showed clear function for FGF21 in regulating chronic adaptive thermogenesis by increasing the transcription of thermogenic genes and enhancing the thermogenic capacity of the organism by “browning” white fat (Fisher et al., 2012).”
BackgroundAdipose tissue dysfunction in obesity, diabetes, and vascular diseases
Hajer, G. R., van Haeften, T. W., & Visseren, F. L. J. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn387 · Cited by 1,410
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Items 101–200 of 213
Timofte, D. V., Tudor, R. C., Mocanu, V., & Labusca, L. S. (2024) · Nutrients · doi:10.3390/nu16234231 · Cited by 16
Moon, H., Choi, J., Song, B., Kim, I.-K., Lim, S., Lee, S., Hwang, K., & Kim, S. W. (2020) · Molecules · doi:10.3390/molecules25235660 · Cited by 15
Mannino, F., Pallio, G., Bitto, A., Altavilla, D., Minutoli, L., Squadrito, V., Arcoraci, V., Giorgi, D. A., Pirrotta, I., Squadrito, F., et al. (2021) · Pharmaceuticals · doi:10.3390/ph14080728 · Cited by 14
Pramsohler, S., Burtscher, M., Rausch, L. K., & Netzer, N. C. (2022) · Life · doi:10.3390/life12040545 · Cited by 14
Adapalene induces adipose browning through the RARβ-p38 MAPK-ATF2 pathway
Lee, N. H., Choi, M. J., Yu, H., Kim, J. I., & Cheon, H. G. (2022) · Archives of Pharmacal Research · doi:10.1007/s12272-022-01384-4 · Cited by 14
Karpęcka-Gałka, E., & Frączek, B. (2024) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2024.1435494 · Cited by 30
Guo, Q., Hu, H., Zhou, Y., Yan, Y., Wei, X., Fan, X., Yang, D., He, H., Oh, Y., Chen, K., et al. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.12.051 · Cited by 14
Giori, I. G., Magliano, D. C., Alexandre‐Santos, B., Fernandes, T., de Oliveira, E. M., Vieira, C. P., Conte‐Júnior, C. A., Ceddia, R. B., da Nóbrega, A. C. L., & Frantz, E. D. C. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29900 · Cited by 14
Novel lipid-mimetic prodrugs delivering active compounds to adipose tissue
Mattarei, A., Rossa, A., Bombardelli, V., Azzolini, M., Spina, M. L., Paradisi, C., Zoratti, M., & Biasutto, L. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.04.034 · Cited by 14
Zhang, Y., Li, F., Dong, Y., Xie, W., & Wang, H. (2024) · The FASEB Journal · doi:10.1096/fj.202400126r · Cited by 13
BAIBA Involves in Hypoxic Training Induced Browning of White Adipose Tissue in Obese Rats
Feng, J., Wang, X., Lu, Y., Yu, C., Wang, X., & Feng, L. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.882151 · Cited by 13
He, Y., Liang, Z., Wang, J., Tang, H., Li, J., Cai, J., & Liao, Y. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.905194 · Cited by 14
Hirakawa, Y., Jao, T., & Inagi, R. (2017) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12777 · Cited by 13
González-Salazar, L. E., Serralde-Zúñiga, A. E., Flores‐López, A., Díaz-Sánchez, J. P., Vera, I., Pichardo‐Ontiveros, E., Guizar-Heredia, R., Hernández-Gómez, K. G., Vigil‐Martínez, A., Arteaga-Sánchez, L., et al. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114522002963 · Cited by 12
Liu, Y., Liu, Z., Ren, Z., Han, Q., Chen, X., Han, J., Qiu, G., & Sun, C. (2024) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2024.106583 · Cited by 12
Tian, S., Liang, Z., Tian, M., Qiu, F., Yu, Y., Mou, H., & Gao, Y. (2024) · Age and Ageing · doi:10.1093/ageing/afae211 · Cited by 14
Jung, D. Y., Suh, N., & Jung, M. H. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120488 · Cited by 12
Dopaminergic and adrenergic receptors synergistically stimulate browning in 3T3-L1 white adipocytes
Haddish, K., & Yun, J. W. (2022) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-022-00928-y · Cited by 11
Correia, B. R. D. O., Rachid, T. L., Glauser, J. S. D. O., Martins, F. F., Mandarim‐de‐Lacerda, C. A., & Souza‐Mello, V. (2019) · Endocrine · doi:10.1007/s12020-019-01969-y · Cited by 10
Dietary Supplementation of Methyl Cedryl Ether Ameliorates Adiposity in High-Fat Diet-Fed Mice
Li, M., Kang, S., Huang, K., & Tong, T. (2023) · Nutrients · doi:10.3390/nu15030788 · Cited by 10
Passos, G. R., de Oliveira, M. G., Ghezzi, A. C., de Mello, G. C., D’Ancona, C. A. L., Teixeira, S. A., Muscará, M. N., Bottoli, C. B. G., de Melo, L. V., de Oliveira, E., et al. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1145860 · Cited by 9
Zhang, J., Yang, J., Yang, N., Ma, J., Lu, D., Dong, Y., Liang, H., Liu, D., & Cang, M. (2020) · Lipids in Health and Disease · doi:10.1186/s12944-020-01230-w · Cited by 10
BMP11 regulates thermogenesis in white and brown adipocytes
Pham, H. G., Mukherjee, S., Choi, M. J., & Yun, J. W. (2021) · Cell Biochemistry and Function · doi:10.1002/cbf.3615 · Cited by 9
Cold Exposure Improves the Anti-diabetic Effect of T0901317 in Streptozotocin-Induced Diabetic Mice
Gao, M., Zhang, C., Ma, Y., & Liu, D. (2015) · The AAPS Journal · doi:10.1208/s12248-015-9746-4 · Cited by 9
Myokines and interorgan crosstalk: bridging exercise to health promotion and disease prevention
Ha, J., Sung, S., & Kim, H. (2025) · Annals of Pediatric Endocrinology & Metabolism · doi:10.6065/apem.2448218.109 · Cited by 10
Molecular epigenetics in the transition of white to brown fat
Chaturvedi, S., Chaturvedi, P., Gupta, P. C., Awasthi, S. K., & Kalani, A. (2025) · Pathology - Research and Practice · doi:10.1016/j.prp.2025.156073 · Cited by 8
Self-citationMyostain is involved in ginsenoside Rb1-mediated anti-obesity
Li, H.-S., Kuang, J., Liu, G., Wu, W., Yin, X., Li, H.-D., Wang, L., Yan, W., Qin, T., Zhang, W., et al. (2022) · Pharmaceutical Biology · doi:10.1080/13880209.2022.2074056 · Cited by 9
Treadmill running alleviates adipose tissue browning and lipolysis in rats with heart failure
Chen, X., Zhang, Y., Li, L., Li, S., & Zhang, J. (2022) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-021-00849-2 · Cited by 8
Inflammation and Oxidative Stress in Adipose Tissue
Martínez‐Fernández, L., Fernández‐Galilea, M., Félix‐Soriano, E., Escoté, X., González‐Muniesa, P., & Moreno-Aliaga, M. J. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-812504-5.00004-0 · Cited by 9
Zhang, L., Wang, J., Zhao, Y., Dubielecka, P. M., Qin, G., Zhuang, S., Chin, E. Y., Liu, P. Y., & Zhao, T. C. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.698714 · Cited by 7
Xing, B., Hou, X., Zhang, G., Wu, H., Feng, N., Li, Y., & Han, G. (2023) · Current Protein and Peptide Science · doi:10.2174/1389203724666230228140808 · Cited by 7
Liang, G., Fang, J., Zhang, P., Ding, S., Zhao, Y., & Feng, Y. (2024) · Open Medicine · doi:10.1515/med-2024-0900 · Cited by 7
Malonate induces the browning of white adipose tissue in high-fat diet induced obesity model
Oki, S., Kageyama, S., Morioka, Y., & Namba, T. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.08.054 · Cited by 6
GADD45A regulates subcutaneous fat deposition and lipid metabolism by interacting with Stat1
You, W., Liu, S., Li, J., Tu, Y., & Shan, T. (2023) · BMC Biology · doi:10.1186/s12915-023-01713-z · Cited by 8
The impact of exercise training on adipose tissue remodelling in cancer cachexia
Ferreira, R. M., Nogueira‐Ferreira, R., Vitorino, R. M. P., Santos, L. L., & Moreira‐Gonçalves, D. (2017) · Porto Biomedical Journal · doi:10.1016/j.pbj.2017.02.006 · Cited by 8
Imrie, H., Viswambharan, H., Haywood, N. J., Bridge, K., Yuldasheva, N. Y., Galloway, S. L., Simmons, K. J., Cubbon, R. M., Sukumar, P., Watt, N. T., et al. (2022) · Adipocyte · doi:10.1080/21623945.2022.2089394 · Cited by 6
Chronic Low or High Nutrient Intake and Myokine Levels
Sierra, A., de Fontes-Junior, A. A., Paz, I. A., Zocoler, C. A. S., Manoel, L. A. D. S., de Menezes, D. C., Rocha, V. A., Barbeiro, H. V., de Souza, H. P., & Cury‐Boaventura, M. F. (2022) · Nutrients · doi:10.3390/nu15010153 · Cited by 6
Fucosterol Promotes Browning in Mouse 3T3 ‐ L1 Adipocytes Through HO ‐1/Nrf2 and AMPK Pathways
Suryaningtyas, I. T., Jung, W., & Je, J. (2025) · BioFactors · doi:10.1002/biof.70035 · Cited by 5
Muzyka, I., Revenko, O., Kovalchuk, I., Savytska, M., Бекесевич, А. М., Kasko, R., & Zayachkivska, О. (2023) · Inflammopharmacology · doi:10.1007/s10787-023-01188-y · Cited by 5
Jakobsen, J. R., Schjerling, P., Kjær, M., Mackey, A. L., & Krogsgaard, M. R. (2022) · Histochemistry and Cell Biology · doi:10.1007/s00418-022-02101-4 · Cited by 5
Ren, S., Zhang, L., Tang, X., Fan, C., Zhao, Y., Cheng, Q., & Zhang, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417420 · Cited by 5
Tyagi, S. C. (2024) · Antioxidants · doi:10.3390/antiox13101225 · Cited by 6
Self-citationAlzamendi, A., Miguel, I., Zubiría, M. G., Gambaro, S. E., Spinedi, E., & Giovambattista, A. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120066 · Cited by 5
Adult Hippocampal Neurogenesis Can Be Enhanced by Cold Challenge Independently From Beigeing Effects
Kim, J. W., Han, K. R., Kim, W., Jung, H. Y., Nam, S. M., Yoo, D. Y., Hwang, I. K., Seong, J. K., & Yoon, Y. S. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00092 · Cited by 4
Dâmaso, A. R., Corgosinho, F. C., Masquio, D. C. L., Figueiredo, N., Kattah, F. M., Cercato, C., Tock, L., & Campos, R. M. D. S. (2026) · Obesity Reviews · doi:10.1111/obr.70093 · Cited by 6
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Bonilla, D. A., Kočí, J., Petro, J. L., & Kreider, R. B. (2024) · Integrated science · doi:10.1007/978-3-031-64292-0_5 · Cited by 5
Zhong, Y., Zhang, J., Tang, K., Kou, W., Xu, S., Yang, H., Liu, L., Luan, P., Mohammed, A., Abdu, F. A., et al. (2021) · Annals of Translational Medicine · doi:10.21037/atm-20-3259 · Cited by 4
Can Exercise-Mediated Adipose Browning Provide an Alternative Explanation for the Obesity Paradox?
Zhao, J., Li, X., Liang, C., & Yan, Y. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26051790 · Cited by 5
Zhao, C., Zhan, M., Du, H., Zhu, K., Chen, S., Song, M., Cao, Y., & Xiao, H. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c08064 · Cited by 3
Enhancing fat graft retention through adipose tissue browning: a systematic review
Qiu, H., Wang, H., Ji, Q., & Wu, D. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04473-5 · Cited by 3
Niu, X., Zhang, Y., Lai, Z., Huang, X., Gao, J., Lu, F., Chang, Q., & Yuan, Y. (2022) · Aesthetic Surgery Journal · doi:10.1093/asj/sjac105 · Cited by 3
Nuclear Receptors in Energy Metabolism
Walth-Hummel, A. A., Herzig, S., & Rohm, M. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-11836-4_4 · Cited by 4
The Role of Proton-Coupled Amino Acid Transporter 2 (SLC36A2) in Cold-Induced Thermogenesis of Mice
Shu, H., Zhang, J., Cheng, D., Zhao, X., Ma, Y., Zhang, C., Zhang, Y., Jia, Z., & Liu, Z. (2023) · Nutrients · doi:10.3390/nu15163552 · Cited by 3
Shabani, M., Daryanoosh, F., Salesi, M., Jahromi, M. K., & Fallahi, A. A. (2018) · The Journal of Qazvin University of Medical Sciences · doi:10.29252/qums.22.3.4 · Cited by 3
Die parakrine und endokrine Funktion der Muskulatur
Heitkamp, H. (2023) · MMW - Fortschritte der Medizin · doi:10.1007/s15006-023-2493-z · Cited by 2
Feng, J., Jia, T., Ren, Y., Zhang, H., & Zhu, W. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122323 · Cited by 2
Fuke, N., Sawada, S., Ito‐Sasaki, T., Inoue, K. Y., Ushida, Y., Sato, I., Matsue, T., Katagiri, H., Ueda, H., & Suganuma, H. (2023) · J — Multidisciplinary Scientific Journal · doi:10.3390/j6040040 · Cited by 2
Bakar, M. F. A. (2024) · PharmaNutrition · doi:10.1016/j.phanu.2024.100388 · Cited by 2
Tahseen, D. (2020) · Medico-Legal Update · doi:10.37506/mlu.v20i1.429 · Cited by 2
Chiyanika, C., & Chu, C. W. (2021) · Archives of Clinical and Biomedical Research · doi:10.26502/acbr.50170199 · Cited by 1
Aleassa, E. M. (2020) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2020.08.027 · Cited by 2
Enhanced thermogenesis in PAS Kinase-deficient male mice
Hurtado-Carneiro, V., Juan-Arévalo, Y., Flores, C. N., Herrero-de-Dios, C. M., Pérez-García, A., Contreras, C., López, M., Álvarez, E., & Sanz, C. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.116757 · Cited by 1
Zhou, G., Wang, R., Fu, C., Du, Y., Li, X., Xia, Q. H., Zhou, J., Li, Z., Li, X., Gong, C., et al. (2025) · International Journal of Obesity · doi:10.1038/s41366-025-02005-y · Cited by 1
An iron-regulated methionine redox axis governs adipose browning and cancer cachexia
Nam, J. S., Ahn, S. S., Shin, Y., Vargas‐Castillo, A., Dixon, M. S., Ahmadi, P., Schilling, K., Zandkarimi, F., Chen, A., Yoon, N. A., et al. (2026) · Nature Cancer · doi:10.1038/s43018-026-01234-y · Cited by 1
Farooqui, A. A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819603-8.00009-2 · Cited by 1
Polyphenolic compounds in the loss of body fat
Abra, C. E., & de Assis, J. R. (2020) · Scientific Electronic Archives · doi:10.36560/13820201047 · Cited by 2
Muzyka, I., Revenko, O., Kovalchuk, I., Savytska, M., Бекесевич, А. М., & Zayachkivska, О. (2023) · Inflammopharmacology · doi:10.1007/s10787-023-01195-z · Cited by 1
Trim21 Regulates the Postnatal Development and Thermogenesis of Brown Adipose Tissue
Hu, Q.-X., Xu, Y., Xiao, T., Peng, R., Li, Z., Xu, G., Yu, B., Li, J., Li, Z., Hou, H., et al. (2023) · Advanced Biology · doi:10.1002/adbi.202300510 · Cited by 1
Obesity: A Multi Perspective of Physiology and Neurobiology Energy Regulation
Meiliana, A., Dewi, N. M., & Wijaya, A. (2024) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v16i1.2840 · Cited by 1
Bradykinin Receptors in Metabolic Disorders: A Comprehensive Review
Branquinho, J. L. D. O., Neves, R. L., Bäder, M., & Pesquero, J. B. (2025) · Drugs and Drug Candidates · doi:10.3390/ddc4030037 · Cited by 1
Jeon, Y., Ha, K., Seo, D. Y., Yeo, J. Y., Choi, S. J., & Han, J. (2017) · IJASS(International Journal of Applied Sports Sciences) · doi:10.24985/ijass.2017.29.1.42 · Cited by 1
Irisin Signaling Pathway is up Regulated by Resistance Training in Ovariectomized Rats
Magosso, N. S. S. (2017) · Obesity & Control Therapies Open Access · doi:10.15226/2374-8354/4/2/00136 · Cited by 1
EET Intervention on HO-1 Prevent Obesity Derived Cardiovascular Diseases
Liu, L., Huang, X., Gao, J.-L., Guo, Y., Di, Y., Sun, S., & Cao, J. (2018) · Journal of Biomolecular Research & Therapeutics · doi:10.4172/2167-7956.1000163 · Cited by 1
Role of MANF, TIMP-2, and Irisin Proteins in Aging
Bi, K., Davidov, S. O., & Chalisova, N. I. (2020) · Biology Bulletin Reviews · doi:10.1134/s2079086420040052 · Cited by 1
Shavandi, M., Naghibi, S., Joneydi, M. S., Vatandoust, M., & Zare, A. (2022) · Journal of Sport and Exercise Physiology · doi:10.52547/joeppa.15.3.35 · Cited by 1
Buchsbaum, M. S., & DeCastro, A. (2014) · Springer eBooks · doi:10.1007/978-1-4471-4920-0_5
Circulating miR-375 Correlates With Response of Human Individuals to Short-Term Cold ExposurePreprint
Seeliger, C., Mengel, L. A., Buekens, L., Mesas‐Fernández, A., Skurk, T., Claussnitzer, M., & Hauner, H. (2021) · Research Square · doi:10.21203/rs.3.rs-382686/v1
Baglien, B. D., & Strong, A. L. (2021) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0000000000008228
Myostain is Involved in GINSENOSIDE-Rb1-mediated anti-obesityPreprint
Li, H.-S., Kuang, J., Liu, G., Wu, W., Yin, X., Li, H.-D., Wang, L., Yan, W., Qin, T., Zhang, W., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-1019424/v1
Buchsbaum, M. S., & DeCastro, A. (2019) · Springer eBooks · doi:10.1007/978-3-030-11748-1_8
Role of Taurine Supplementation in Obesity: Stimulating Fats to Burn in Cellular Power Plants
Heidari, R., & Ommati, M. M. (2023) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815124484123010013
Evaluation of Serum Irisin Levels in Patients Developing Nephropathy Due to Type 2 Diabetes Mellitus
Dağlıoğlu, G., Döğüş, Y., İçen, G., Kibar, F., Evran, M., Ünal, İ., & Öztürk, Ö. G. (2023) · JEURMEDS · doi:10.5578/jeurmeds.20235048
Zhuang, P., Li, H., Jia, W. P., Shou, Q., Zhu, Y., Mao, L., Wang, W., Wu, F. H., Chen, X., Wan, X., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16606932
Zhuang, P., Li, H., Jia, W. P., Shou, Q., Zhu, Y., Mao, L., Wang, W., Wu, F. H., Chen, X., Wan, X., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16606935
Gusenbekova, D. G., Moscow, R. F., As, A., & Korotkova, T. N. (2024) · Doctor Ru · doi:10.31550/1727-2378-2024-23-4-54-59
Shrier, I. (2025) · Observational Studies · doi:10.1353/obs.2025.a963648
Ge, Y., Liu, A., Meng, F., Zhang, R., Wang, J., Dang, Q., Wu, G. C., & Zhang, Y. (2025) · Research Square · doi:10.21203/rs.3.rs-7124697/v1
Browning effect of LncRNA00602 in Ad36-induced differentiated adipocytes
Gao, J., Meng, X.-Y., Jiao, Y., Abudukeremu, A., Nuermaimaiti, N., Ma, W., Li, X., & Guan, Y. (2025) · Medicine · doi:10.1097/md.0000000000043816
Autophagy in adipose tissue thermogenic function
Villarroya, J., Blasco-Roset, A., & Giralt, M. (2025) · International review of cytology · doi:10.1016/bs.ircmb.2025.10.006
Zhuang, P., Li, H., Jia, W., Shou, Q., Zhu, Y., Mao, L., Wang, W., Wu, F., Chen, X., Wan, X., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16606926
You, W., Liu, S., Li, J., Tu, Y., & Shan, T. (2024) · Figshare · doi:10.6084/m9.figshare.26624536
Zhang, J., Yang, J., Yang, N., Ma, J., Lu, D., Dong, Y., Liang, H., Liu, D. J., & Cang, M. (2020) · Figshare · doi:10.6084/m9.figshare.11984757
You, W., Liu, S., Li, J., Tu, Y., & Shan, T. (2024) · Figshare · doi:10.6084/m9.figshare.26624545
You, W., Liu, S., Li, J., Tu, Y., & Shan, T. (2024) · Figshare · doi:10.6084/m9.figshare.26624539
You, W., Liu, S., Li, J., Tu, Y., & Shan, T. (2024) · Figshare · doi:10.6084/m9.figshare.26624548
You, W., Liu, S., Li, J., Tu, Y., & Shan, T. (2024) · Figshare · doi:10.6084/m9.figshare.24269339
You, W., Liu, S., Li, J., Tu, Y., & Shan, T. (2023) · Figshare · doi:10.6084/m9.figshare.24269298
Zhu, X., Du, S., Yan, Q., Min, C., Zhou, N., Zhou, W., & Li, X. (2021) · Figshare · doi:10.6084/m9.figshare.16909989
You, W., Liu, S., Li, J., Tu, Y., & Shan, T. (2024) · Figshare · doi:10.6084/m9.figshare.26624551
Metadata
- Authors
- Jeremic, N., Chaturvedi, P., & Tyagi, S. C.
- Affiliations
- University of Louisville (US)
- Corresponding author
- Tyagi, Suresh C.
- Venue
- Journal of Cellular Physiology
- Publisher
- Wiley
- Published
- 2016-06-21
- Volume
- 232
- Issue
- 1
- Pages
- 61-68
- ISSN
- 0021-9541 (ISSN-L)
- PMC
- PMC6567990
- OpenAlex
- W2412754298
- Cited by
- 211
- References
- 91
- Citations by year
- 2026: 11 · 2025: 13 · 2024: 19 · 2023: 30 · 2022: 26 · 2021: 31 · 2020: 27 · 2019: 8 · 2018: 20 · 2017: 20 · 2016: 4
- FWCI
- 2.04
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Cellular Physiology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH (HL-74185, HL-108621)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Peroxisome Proliferator-Activated Receptors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- white adipose tissue browning, brown adipose tissue, thermogenesis, obesity, type 2 diabetes, musclin, TFAM, mitochondrial biogenesis, PPARγ agonists, physical activity, beta-aminoisobutyric acid, GABA, JAK inhibition, irisin, perivascular adipose tissue, metabolic disorders, cardiovascular disease
- MeSH terms
- Animals, Adipose Tissue, Brown, Diabetes Mellitus, Type 2, Humans, Insulin Resistance, Obesity, Thermogenesis, Adipose Tissue, White
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