Pilot study of using neutral protamine hagedorn insulin to counteract the effect of methylprednisolone in hospitalized patients with diabetes
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NPH insulin might have an advantage over long-acting insulin because its effects show a similar timeline to glucocorticoid-induced afternoon peaks of hyperglycaemia.
“This approach might have an advantage over long-acting insulin because its effects show a similar timeline to that of glucocorticoid-induced afternoon peaks of hyperglycaemia.56 57”
The intermediate-acting NPH insulin provides good control of afternoon peaks of blood glucose caused by glucocorticoids.
“The intermediate-acting NPH insulin provides good control of afternoon peaks of blood glucose caused by glucocorticoids.”
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- Authors
- Seggelke, S. A., Gibbs, J., & Draznin, B.
- Affiliations
- University of Colorado Denver (US)
- Venue
- Journal of Hospital Medicine
- Publisher
- Wiley
- Published
- 2011-03
- Volume
- 6
- Issue
- 3
- Pages
- 175-176
- ISSN
- 1553-5592 (ISSN-L)
- 1553-5606
- OpenAlex
- W2031394884
- Cited by
- 42
- References
- 4
- Citations by year
- 2026: 2 · 2025: 1 · 2023: 2 · 2022: 6 · 2021: 4 · 2020: 4 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 3 · 2015: 3 · 2014: 3 · 2013: 5 · 2012: 3
- FWCI
- 3.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Hospital Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- neutral protamine Hagedorn insulin, NPH insulin, methylprednisolone, diabetes mellitus, hospitalized patients, corticosteroid-induced hyperglycemia, insulin therapy
- MeSH terms
- Cystic Fibrosis, Diabetes Mellitus, Hospitalization, Humans, Insulin, Isophane, Methylprednisolone, Pilot Projects
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