The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
The neuropathogenesis of HIV-1 infection
Abstract
HIV infection in brain revolves around productive viral replication in cells of mononuclear phagocyte lineage, including brain macrophages, microglia, and multinucleated giant cells [1–4]. Together, they are the instigators for cellular and viral neurotoxic activities [5–10]. Several published reports show that viral and/or cellular products produced from HIV-1-infected macrophages injure neurons and induce glial proliferation during advancing central nervous system (CNS) infection [11–18]. These findings are supported by the apparent discrepancy between the distribution and numbers of virus-infected cells and concomitant brain tissue pathology [5, 19]. Whether these soluble factors are indirectly responsible for neuronal damage remains undefined. The identification and regulation of neurotoxins produced from HIV-infected macrophages are central to uncovering how HIV mediates CNS disease. The authors who contributed to this work represent laboratories with overlapping areas of expertise. Broad-based complementary hypotheses regarding HIV neuropathogenesis are now provided. J. Leukoc. Biol. 56: 389–398; 1994.
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Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.
Dawson, V. L., Dawson, T. M., London, E. D., Bredt, D. S., & Snyder, S. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.14.6368 · Cited by 2,174
Detection of AIDS Virus in Macrophages in Brain Tissue from AIDS Patients with Encephalopathy
Koenig, S., Gendelman, H. E., Orenstein, J. M., Dal Canto, M. C., Pezeshkpour, G. H., Yungbluth, M., Janotta, F., Aksamit, A., Martin, M. A., & Fauci, A. S. (1986) · Science · doi:10.1126/science.3016903 · Cited by 1,698
Self-citationWiley, C. A., Schrier, R. D., Nelson, J. A., Lampert, P. W., & Oldstone, M. B. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.18.7089 · Cited by 1,243
A novel neuronal messenger molecule in brain: The free radical, nitric oxide
Dawson, T. M., Dawson, V. L., & Snyder, S. H. (1992) · Annals of Neurology · doi:10.1002/ana.410320302 · Cited by 834
Neurotransmitter regulation of neuronal outgrowth, plasticity and survival
Lipton, S. A., & Kater, S. B. (1989) · Trends in Neurosciences · doi:10.1016/0166-2236(89)90026-x · Cited by 727
Self-citationMechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta.
Vodovotz, Y., Bogdan, C., Paik, J., Xie, Q. W., & Nathan, C. (1993) · The Journal of experimental medicine · doi:10.1084/jem.178.2.605 · Cited by 655
Chen, H., Pellegrini, J., Aggarwal, S., Lei, S., Warach, S., Jensen, F., & Lipton, S. (1992) · The Journal of Neuroscience · doi:10.1523/jneurosci.12-11-04427.1992 · Cited by 629
Self-citationSecretion of Neurotoxins by Mononuclear Phagocytes Infected with HIV-1
Giulian, D., Vaca, K., & Noonan, C. A. (1990) · Science · doi:10.1126/science.2148832 · Cited by 620
Brenneman, D. E., Westbrook, G. L., Fitzgerald, S. P., Ennist, D. L., Elkins, K. L., Ruff, M. R., & Pert, C. B. (1988) · Nature · doi:10.1038/335639a0 · Cited by 608
Cytokine expression in the brain during the acquired immunodeficiency syndrome
Tyor, W. R., Glass, J. D., Griffin, J. W., Becker, P. S., McArthur, J. C., Bezman, L., & Griffin, D. E. (1992) · Annals of Neurology · doi:10.1002/ana.410310402 · Cited by 568
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Ellis, R., Langford, D., & Masliah, E. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2040 · Cited by 517
Depression in HIV Infected Patients: a Review
Nanni, M. G., Caruso, R., Mitchell, A. J., Meggiolaro, E., & Grassi, L. (2015) · Current Psychiatry Reports · doi:10.1007/s11920-014-0530-4 · Cited by 511
McHugh, D., Hu, S. S., Rimmerman, N., Juknat, A., Vogel, Z., Walker, J. M., & Bradshaw, H. B. (2010) · BMC Neuroscience · doi:10.1186/1471-2202-11-44 · Cited by 323
Janabi, N., Peudenier, S., Héron, B., Ng, K. H., & Tardieu, M. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(94)11792-h · Cited by 280
Self-citationPhosphorylation of Claudin-5 and Occludin by Rho Kinase in Brain Endothelial Cells
Yamamoto, M., Ramirez, S. H., Sato, S., Kiyota, T., Cerny, R. L., Kaibuchi, K., Persidsky, Y., & Ikezu, T. (2008) · The American Journal of Pathology · doi:10.2353/ajpath.2008.070076 · Cited by 241
Metadata
- Authors
- Gendelman, H. E., Lipton, S. A., Tardieu, M., Bukrinsky, M. I., & Nottet, H. S. L. M.
- Venue
- Journal of Leukocyte Biology
- Publisher
- Oxford University Press (OUP)
- Published
- 1994-09-01
- Volume
- 56
- Issue
- 3
- Pages
- 389-398
- ISSN
- 0741-5400 (ISSN-L)
- 1938-3673
- OpenAlex
- W1936351921
- Cited by
- 272
- References
- 41
- FWCI
- 4.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gendelman, H. E., Lipton, S. A., Tardieu, M., Bukrinsky, M. I., & Nottet, H. S. L. M. (1994). The neuropathogenesis of HIV-1 infection. Journal of Leukocyte Biology. https://doi.org/10.1002/jlb.56.3.389
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