The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.
Clinical applications of chemical exchange saturation transfer (CEST) MRI
Open accessAbstract
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has been developed and employed in multiple clinical imaging research centers worldwide. Selective radiofrequency (RF) saturation pulses with standard 2D and 3D MRI acquisition schemes are now routinely performed, and CEST MRI can produce semiquantitative results using magnetization transfer ratio asymmetry (MTR asym) analysis while accounting for B 0 inhomogeneity. Faster clinical CEST MRI acquisition methods and more quantitative acquisition and analysis routines are under development. Endogenous biomolecules with amide, amine, and hydroxyl groups have been detected during clinical CEST MRI studies, and exogenous CEST agents have also been administered to patients. These CEST MRI tools show promise for contributing to assessments of cerebral ischemia, neurological disorders, lymphedema, osteoarthritis, muscle physiology, and solid tumors. This review summarizes the salient features of clinical CEST MRI protocols and critically evaluates the utility of CEST MRI for these clinical imaging applications. Level of Evidence: 5 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2018;47:11–27.
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Chemical exchange saturation transfer (CEST): what is in a name and what isn't?
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Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers
Wahsner, J., Gale, E. M., Rodríguez-Rodríguez, A., & Caravan, P. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00363 · Cited by 1,603
Noninvasive Detection of Extracellular pH in Human Benign and Malignant Liver Tumors Using CEST MRI
Tang, Y., Xiao, G., Shen, Z., Zhuang, C., Xie, Y., Zhang, X., Yang, Z., Guan, J., Shen, Y., Chen, Y., et al. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.578985 · Cited by 56
Engineering clinical translation of OGSE diffusion MRI
Zhu, A., Michael, E. S., Li, H., Sprenger, T., Hua, Y., Lee, S., Yeo, D. T. B., McNab, J. A., Hennel, F., Fieremans, E., et al. (2025) · Magnetic Resonance in Medicine · doi:10.1002/mrm.30510 · Cited by 13
Goldenberg, J. M., Cárdenas‐Rodríguez, J., & Pagel, M. D. (2019) · Magnetic Resonance in Medicine · doi:10.1002/mrm.27439 · Cited by 10
Self-citation
Metadata
- Authors
- Jones, K. M., Pollard, A. C., & Pagel, M. D.
- Venue
- Journal of Magnetic Resonance Imaging
- Publisher
- Wiley
- Published
- 2017-08-09
- Volume
- 47
- Issue
- 1
- Pages
- 11-27
- ISSN
- 1053-1807 (ISSN-L)
- 1522-2586
- OpenAlex
- W2744561951
- Cited by
- 287
- References
- 95
- FWCI
- 17.04
- Type
- journal article
- Language
- en
- Open access
- bronze
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