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Cited by 183

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Endogenous adult neural stem cells: Limits and potential to repair the injured central nervous system

Picard‐Riera, Nathalie, Nait‐Oumesmar, Brahim, Baron‐Van Evercooren, Anne·2004·Journal of Neuroscience Research

Abstract

Mitotic activity persists in various regions of the adult mammal CNS. While evidences of neurogenesis appeared, many studies focused on the features of the adult stem cells from germinative areas such as the subventricular zone of the lateral ventricles, the dentate gyrus of the hippocampus, the cortex, the fourth ventricle and the central canal of the spinal cord. In the present paper, we review the potentialities of the adult germinative areas in terms of proliferation, migration and differentiation in non pathological situation and in response to different type of CNS injury. Adult endogenous stem cells are activated in response to various injuries but their capacities to migrate and to undergo either neurogenesis or gliogenesis differ according to the lesion‐type and the germinative zone from which they arise. Different works demonstrated that epigenic factors such as growth factors can enhance the repair potential of the adult stem cells. Reactivation and mobilization of endogenous stem cells as well as demonstration of their long‐term survival and functionality appear to be interesting strategies to investigate in order to promote endogenous repair of the adult CNS. © 2004 Wiley‐Liss, Inc.

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Metadata

Authors
Picard‐Riera, N., Nait‐Oumesmar, B., & Baron‐Van Evercooren, A.
Venue
Journal of Neuroscience Research
Publisher
Wiley
Published
2004-03-08
Volume
76
Issue
2
Pages
223-231
ISSN
  • 0360-4012 (ISSN-L)
  • 1097-4547
OpenAlex
W2002560617
Cited by
183
References
11
FWCI
4.35
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Endogenous adult neural stem cells: Limits and potential to repair the injured central nervous system. https://app.cochat.ai/papers/10.1002/jnr.20040
The paper
Picard‐Riera, N., Nait‐Oumesmar, B., & Baron‐Van Evercooren, A. (2004). Endogenous adult neural stem cells: Limits and potential to repair the injured central nervous system. Journal of Neuroscience Research. https://doi.org/10.1002/jnr.20040

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.