Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications
Zhong, Qian, Xiao, Xina, Qiu, Yijie, Xu, Zhiqiang, Chen, Chunyu, Chong, Baochen, Zhao, Xinjun, Hai, Shan +3 more·2023·MedComm
DOI 10.1002/mco2.261
Cites (1,499)
Items 801–1,000 of 1,498
- Chromatin remodeling due to degradation of citrate carrier impairs osteogenesis of aged mesenchymal stem cellsAndromachi Pouikli, Swati Parekh, Monika Maleszewska, Chrysa Nikopoulou, Maarouf Baghdadi, Ignacio J. Tripodi, Kat Folz‐Donahue, Yvonne Hinze, Andrea Mesaros, David A. Hoey et al. · 2021 · Nature Aging
- Protein carbamylation is associated with heart failure and mortality in diabetic patients with end stage renal diseaseC. Drechsler, Sahir Kalim, Julia B. Wenger, Pirianthini Suntharalingam, Tammy Hod, Ravi I. Thadhani, S. Karumanchi, C. Wanner, A. Berg · 2015 · Kidney International
- α-Synuclein enhances histone H3 lysine-9 dimethylation and H3K9me2-dependent transcriptional responsesNaoto Sugeno, Sandra Jäckel, Aaron Voigt, Zinah Wassouf, Julia Maria Schulze-Hentrich, Philipp J. Kahle · 2016 · Scientific Reports
- Isolation and characterization of cDNA clones encoding rat skeletal muscle peptidylarginine deiminaseKazutada Watanabe, T. Senshu · 1989 · Journal of Biological Chemistry
- Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapyRyuji Hamamoto, Yusuke Nakamura · 2016 · Cancer Science
- In-depth Site-specific Analysis of N-glycoproteome in Human Cerebrospinal Fluid and Glycosylation Landscape Changes in Alzheimer's DiseaseZhengwei Chen, Qinying Yu, Qing Yu, Jillian Johnson, Richard David Shipman, Xiaofang Zhong, Junfeng Huang, Sanjay Asthana, Cynthia M. Carlsson, Ozioma C. Okonkwo et al. · 2021 · Molecular & Cellular Proteomics
- SENP1 protects against myocardial ischaemia/reperfusion injury via a HIF1α-dependent pathwayJianmin Gu, Yuqi Fan, Xiaobing Liu, Lihuang Zhou, Jinke Cheng, Rong Cai, Song Xue · 2014 · Cardiovascular Research
- Protein arginine methyltransferase 1 regulates hepatic glucose production in a FoxO1-dependent mannerDahee Choi, Kyoung‐Jin Oh, Hye-Sook Han, Young-Sil Yoon, Chang-Yun Jung, Seong‐Tae Kim, Seung‐Hoi Koo · 2012 · Hepatology
- Protein Acyltransferase DHHC3 Regulates Breast Tumor Growth, Oxidative Stress, and SenescenceChandan Sharma, Hong-Xing Wang, Qinglin Li, Konstantin Knoblich, Emily Reisenbichler, Andrea L. Richardson, Martin E. Hemler · 2017 · Cancer Research
- O -GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2Pei-Wen Lo, Jiun‐Jie Shie, Chein‐Hung Chen, Chung‐Yi Wu, Tsui-Ling Hsu, Chi‐Huey Wong · 2018 · Proceedings of the National Academy of Sciences
- Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stressXie Ge, Zhaowanyue He, Chun Cao, Tongmin Xue, Jun Jing, Rujun Ma, Zhao Wei, Ling Liu, Kadiliya Jueraitetibaike, Jinzhao Ma et al. · 2022 · Redox Biology
- Effects of MEK5/ERK5 Association on Small Ubiquitin-Related Modification of ERK5: Implications for Diabetic Ventricular Dysfunction After Myocardial InfarctionTetsuro Shishido, Chang-Hoon Woo, Bo Ding, Carolyn McClain, Carlos Augusto Fernandes Molina, Yan Chen, Jay Yang, Jun‐ichi Abe · 2008 · Circulation Research
- DAPK3 inhibits gastric cancer progression via activation of ULK1-dependent autophagyGuanman Li, Lei Li, Meng-Qing Li, Xu Chen, Qiao Su, Zhijuan Deng, Hai-Bo Liu, Bin Li, Wenhui Zhang, Yongxu Jia et al. · 2020 · Cell Death and Differentiation
- Function and Mechanism of Novel Histone Posttranslational Modifications in Health and DiseaseHuiwen Xu, Maoyan Wu, Xiumei Ma, Wei Gang Huang, Yong Xu · 2021 · BioMed Research International
- Mammalian ACSF3 Protein Is a Malonyl-CoA Synthetase That Supplies the Chain Extender Units for Mitochondrial Fatty Acid SynthesisAndrzej Witkowski, Jennifer L. Thweatt, Stuart Smith · 2011 · Journal of Biological Chemistry
- The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutationJie He, Zhihui Zhou, Xin Sun, Zunhua Yang, Pengwu Zheng, Shan Xu, Wufu Zhu · 2020 · European Journal of Medicinal Chemistry
- Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals potential therapeutic strategiesLi, Yan, Xu, Chen, Wang, Bing, Xu, Fujiang, Ma, Fahan, Qu, Yuanyuan, Jiang, Dongxian, Li, Kai, Feng, Jinwen, Tian, Sha et al. · 2022 · Nature Communications
- Defective sumoylation pathway directs congenital heart diseaseJun Wang, Li Chen, Shu Wen, Huiping Zhu, Wei Yu, Ivan P. G. Moskowitz, Gary Michael Shaw, Richard H. Finnell, Robert John Schwartz · 2011 · Birth Defects Research Part A Clinical and Molecular Teratology
- Epigenetic Modulation of Stem Cells in Neurodevelopment: The Role of Methylation and AcetylationMartyna Podobińska, Ilona Szabłowska‐Gadomska, Justyna Augustyniak, Ioanna Sandvig, Axel Sandvig, Leonora Bużańska · 2017 · Frontiers in Cellular Neuroscience
- Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and functionLenan Zhuang, Younghoon Jang, Young-Kwon Park, Ji‐Eun Lee, Shalini Jain, Eugene Froimchuk, Aaron Broun, Chengyu Liu, Oksana Gavrilova, Kai Ge · 2018 · Nature Communications
- Regulation of Golgi turnover by CALCOCO1-mediated selective autophagyThaddaeus Mutugi Nthiga, Birendra Kumar Shrestha, Jack‐Ansgar Bruun, Kenneth Bowitz Larsen, Trond Lamark, Terje Johansen · 2021 · The Journal of Cell Biology
- Midostaurin: a magic bullet that blocks mast cell expansion and activationValent, P., Akin, C., Hartmann, K., George, T.I., Sotlar, K., Peter, B., Gleixner, K.V., Blatt, K., Sperr, W.R., Manley, P.W. et al. · 2017 · Annals of Oncology
- Class I histone deacetylases 1, 2 and 3 are highly expressed in classical Hodgkin's lymphomaHeiner Adams, Florian Rudolf Fritzsche, Stephan Dirnhofer, Glen Kristiansen, Alexandar Tzankov · 2010 · Expert Opinion on Therapeutic Targets
- An Expanding Repertoire of Protein AcylationsYuxuan Xu, Zhenyu Shi, Li Bao · 2022 · Molecular & Cellular Proteomics
- CARM1 and PRMT1 are dysregulated in lung cancer without hierarchical featuresRania El Akoum, Guillaume Gauchotte, Abderrahim Oussalah, Marie-Pierre Wissler, Christelle Clément-Duchêne, Jean-Michel Vignaud, Jean‐Louis Guéant, Farès Namour · 2013 · Biochimie
- Peptidylarginine deiminases and deimination in biology and pathology: Relevance to skin homeostasisStéphane Chavanas, Marie‐Claire Méchin, Rachida Nachat, Véronique Adoue, Fanny Coudane, Guy Serre, Michel Simon · 2006 · Journal of Dermatological Science
- Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in LiverLi-Fen Shen, Yi‐Ju Chen, Kai-Ming Liu, Amir N. Saleem Haddad, I-Wen Song, Hsiao-Yuh Roan, Li-Ying Chen, Jeffrey J-Y Yen, Yu‐Ju Chen, J Wu et al. · 2017 · Scientific Reports
- K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycleYuanyuan Yu, Qingyun Zheng, Satchal K. Erramilli, Man Pan, Seong-Jin Park, Yuan Xie, Jingxian Li, Jingyi Fei, Anthony A. Kossiakoff, Lei Liu et al. · 2021 · Nature Chemical Biology
- Update on peptidylarginine deiminases and deimination in skin physiology and severe human diseasesMarie‐Claire Méchin, Mireille Sebbag, J. Arnaud, Rachida Nachat, Céline Foulquier, Véronique Adoue, Fanny Coudane, H. Duplan, Anne-Marie Schmitt, Stéphane Chavanas et al. · 2007 · International Journal of Cosmetic Science
- Synapses, spines and kinases in mammalian learning and memory, and the impact of agingEddy A. van der Zee · 2014 · Neuroscience & Biobehavioral Reviews
- Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasisDan He, Huijin Feng, Belen Sundberg, Jiaxing Yang, Justin Powers, Alec H. Christian, John Erby Wilkinson, Cian Monnin, Daina Zofija Avizonis, Craig J. Thomas et al. · 2022 · Molecular Cell
- The Human Histone Acetyltransferase P/CAF is a Promiscuous Histone PropionyltransferaseHans Leemhuis, Len C. Packman, Karl P. Nightingale, Florian Hollfelder · 2008 · ChemBioChem
- SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3Filipa Quintela Vieira, Pedro Costa‐Pinheiro, Diogo Almeida-Rios, Inês C. R. Graça, Sara Monteiro‐Reis, Susana Simoes‐Sousa, Isa C. Carneiro, Elsa Sousa, Maria Inês Godinho, Fátima Baltazar et al. · 2015 · Oncotarget
- S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating AutophagyQingwen Qian, Zeyuan Zhang, Allyson Orwig, Songhai Chen, Wen‐Xing Ding, Yanji Xu, Ryan C. Kunz, Nicholas R. L. Lind, Jonathan S. Stamler, Ling Yang · 2017 · Diabetes
- SMYD3: An Oncogenic Driver Targeting Epigenetic Regulation and Signaling PathwaysCinzia Bottino, Alessia Peserico, Cristiano Simone, Giuseppina Caretti · 2020 · Cancers
- DasatinibMarkus Lindauer, Andreas Hochhaus · 2014 · Recent results in cancer research/Recent Results in Cancer Research
- Fatiguing contractions increase protein S-glutathionylation occupancy in mouse skeletal musclePhilip Adam Kramer, Jicheng Duan, Matthew J. Gaffrey, Anil K. Shukla, Lu Wang, Theo K. Bammler, Weijun Qian, David Joseph Marcinek · 2018 · Redox Biology
- MYC Dysregulates Mitosis, Revealing Cancer VulnerabilitiesJulia Rohrberg, Daniel Van de Mark, Meelad Amouzgar, Joyce V. Lee, Moufida Taileb, Alexandra N. Corella, Seda Kilinc, Jeremy R. Williams, Marie‐Lena Jokisch, Roman Camarda et al. · 2020 · Cell Reports
- PDCD5 Interacts with Tip60 and Functions as a Cooperator in Acetyltransferase Activity and DNA Damage-Induced ApoptosisLanjun Xu, Yingyu Chen, Quansheng Song, Dong Ming Xu, Ying Wang, Dalong Ma · 2009 · Neoplasia
- Insulin Represses Phosphoenolpyruvate Carboxykinase Gene Transcription by Causing the Rapid Disruption of an Active Transcription Complex: A Potential Epigenetic EffectRobert K. Hall, Xiaohui L. Wang, Leena George, Stephen R. Koch, Daryl K. Granner · 2006 · Molecular Endocrinology
- Impact of protein acetylation in inflammatory lung diseasesKazuhiro Ito, Catherine E. Charron, Ian Michael Adcock · 2007 · Pharmacology & Therapeutics
- Synthesis, Modification and Turnover of Proteins during AgingSuresh I. S. Rattan · 2010 · Advances in experimental medicine and biology
- SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary FibrosisMaximilianos Elkouris, Haroula Kontaki, Athanasios Stavropoulos, Anastasia Antonoglou, Kostas C. Nikolaou, Martina K. Samiotaki, Eszter Szántai, Dimitra Saviolaki, Peter J. Brown, Paschalis Sideras et al. · 2016 · Cell Reports
- Lenvantinib: A Tyrosine Kinase Inhibitor of VEGFR 1-3, FGFR 1-4, PDGFRα, KIT and RETStefanie Zschäbitz, Carsten Grüllich · 2018 · Recent results in cancer research/Recent Results in Cancer Research
- Anti-Citrulline Antibodies in the Diagnosis and Prognosis of Rheumatoid Arthritis: Evolving ConceptsAmalia Raptopoulou, Prodromos I. Sidiropoulos, Maria Katsouraki, Dimitrios T. Boumpas · 2007 · Critical Reviews in Clinical Laboratory Sciences
- Palmitoylation of MDH2 by ZDHHC18 activates mitochondrial respiration and accelerates ovarian cancer growthXuan Pei, Kai-Yue Li, Yuan Shen, Jin-Tao Li, Mingzhu Lei, Caiyun Fang, Haojie Lu, Huijuan Yang, Wenyu Wen, Miao Yin et al. · 2022 · Science China Life Sciences
- Role of histone acetyltransferases and histone deacetylases in adipocyte differentiation and adipogenesisYuanfei Zhou, Jian Peng, Siwen Jiang · 2014 · European Journal of Cell Biology
- Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndromeRichard S. Beard, Xiaoyuan Yang, Jamie E. Meegan, Jonathan Overstreet, Clement G.Y. Yang, John A. Elliott, Jason J. Reynolds, Byeong J. Cha, Christopher D. Pivetti, David A. Mitchell et al. · 2016 · Nature Communications
- Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue RegenerationMailyn A. Nishiguchi, Casey A. Spencer, Denis H. Y. Leung, Thomas Leung · 2018 · Cell Reports
- Mitochondrial Hyperacetylation in the Failing Hearts of Obese Patients Mediated Partly by a Reduction in SIRT3: The Involvement of the Mitochondrial Permeability Transition PoreElena C. Castillo, José A Morales, Héctor Chapoy‐Villanueva, Christian Silva‐Platas, Niria Treviño‐Saldaña, Carlos Enrique Guerrero-Beltrán, Judith Bernal‐Ramírez, Alejandro Torres‐Quintanilla, Noemà GarcÃa, Keith A. Youker et al. · 2019 · Cellular Physiology and Biochemistry
- Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamicsLuana Naia, Catarina Carmo, Susanna Campesan, Lígia Fão, Victoria E. Cotton, Jorge Valero, Carla Lopes, Tatiana Rosado Rosenstock, Flaviano Giorgini, Ana Cristina Rego · 2020 · Free Radical Biology and Medicine
- Macrophage IRX3 promotes diet-induced obesity and metabolic inflammationJingfei Yao, Dongmei Wu, Chunyan Zhang, Ting Yan, Yiheng Zhao, Hongyu Shen, Kaili Xue, Xun Huang, Zihao Wang, Yifu Qiu · 2021 · Nature Immunology
- BZW1 Facilitates Glycolysis and Promotes Tumor Growth in Pancreatic Ductal Adenocarcinoma Through Potentiating eIF2α PhosphorylationZengxun Li, Yi Ge, Jie Dong, Hongwei Wang, Tiansuo Zhao, Xiuchao Wang, Jing Liu, Song Gao, Lei Shi, Shengyu Yang et al. · 2021 · Gastroenterology
- PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD)Tamara Ratovitski, Nicolas Arbez, Jacqueline C. Stewart, Ekaterine Chighladze, Christopher A. Ross · 2015 · Cell Cycle
- Multiple roles for O‐glycans in Notch signallingShweta Varshney, Pamela Stanley · 2018 · FEBS Letters
- Identification of lysine isobutyrylation as a new histone modification markZhesi Zhu, Zhen Hai Han, Levon Halabelian, Xiangkun Yang, Jun Ding, Nawei Zhang, Liza Ngo, Jiabao Song, Hong Zeng, Maomao He et al. · 2020 · Nucleic Acids Research
- Multikinase inhibitors in thyroid cancer: timing of targeted therapyMatti L. Gild, Venessa Tsang, Roderick John Clifton-Bligh, Bruce G. Robinson · 2021 · Nature Reviews Endocrinology
- FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesisXiaolong Zhu, Cong Qiu, Yiran Wang, Yuan‐Qing Jiang, Yefeng Chen, Linge Fan, Ruizhe Ren, Yunyun Wang, Yu Chen, Yanzhi Feng et al. · 2022 · Proceedings of the National Academy of Sciences
- The Role of Atypical Ubiquitin Chains in the Regulation of the Antiviral Innate Immune ResponseMariska van Huizen, Marjolein Kikkert · 2020 · Frontiers in Cell and Developmental Biology
- CaMKII Serine 280 O-GlcNAcylation Links Diabetic Hyperglycemia to ProarrhythmiaBence Hegyi, Anna Fasoli, Christopher Y. Ko, Benjamin W. Van, Chidera C. Alim, Erin Y. Shen, Marisa M. Ciccozzi, Srinivas Tapa, Crystal M. Ripplinger, Jeffrey R. Erickson et al. · 2021 · Circulation Research
- Management of Common Toxicities in Metastatic NSCLC Related to Anti-Lung Cancer Therapies with EGFR–TKIsMelosky, Barbara, Hirsh, Vera · 2014 · Frontiers in Oncology
- Developmental control of sumoylation pathway proteins in mouse male germ cellsSophie La Salle, Fengyun Sun, Xiang-Dong Zhang, Michael J. Matunis, Mary Ann Handel · 2008 · Developmental Biology
- Protein carbamylation exacerbates vascular calcificationDaisuke Mori, Isao Matsui, Akihiro Shimomura, Nobuhiro Hashimoto, Ayumi Matsumoto, Karin Shimada, Satoshi Yamaguchi, Tatsufumi Oka, Keiichi Kubota, Sayoko Yonemoto et al. · 2018 · Kidney International
- Protein Paucimannosylation Is an Enriched N‐Glycosylation Signature of Human CancersS. Chatterjee, Ling Y. Lee, Rebeca Kawahara, Jodie L. Abrahams, Barbara Adamczyk, Merrina Anugraham, Christopher Ashwood, Zeynep Sumer-Bayraktar, Matthew T. Briggs, Jenny H. L. Chik et al. · 2019 · Proteomics
- Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant ProgressionXueran Chen, Aijun Hao, Xian Li, Kaiqin Ye, Chenggang Zhao, Haoran Yang, Huihui Ma, Lei Hu, Zhiyang Zhao, Lizhu Hu et al. · 2019 · Theranostics
- The role of sirtuins in Alzheimer's diseaseRakhee Lalla, Gizem Dönmez · 2013 · Frontiers in Aging Neuroscience
- Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunctionEun Young Kim, Li Chen, Yanlin Ma, Wei Yu, Jiang Chang, Ivan P. G. Moskowitz, Jun Wang · 2011 · Journal of Molecular and Cellular Cardiology
- Diabetes Induces Lysine Acetylation of Intermediary Metabolism Enzymes in the KidneyHari Kosanam, Kerri Thai, Yanling Zhang, Andrew Advani, Kim Alexander Connelly, Eleftherios P. Diamandis, Richard E. Gilbert · 2014 · Diabetes
- Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammalsLin Fu, Hailong Wu, Steven Yan Cheng, Daming Gao, Lei Zhang, Yun Zhao · 2016 · eLife
- Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP)Tamanini, Emiliano, Buck, Ildiko M., Chessari, Gianni, Chiarparin, Elisabetta, Day, James E. H., Frederickson, Martyn, Griffiths-Jones, Charlotte M., Hearn, Keisha, Heightman, Tom D., Iqbal, Aman et al. · 2017 · Journal of Medicinal Chemistry
- JMJD2C promotes colorectal cancer metastasis via regulating histone methylation of MALAT1 promoter and enhancing β-catenin signaling pathwayXinnan Wu, Ruixiao Li, Qing Song, Chengcheng Zhang, Ru Jia, Zhifen Han, Lihong Zhou, Hua Xiu Sui, Xuan Liu, Huirong Zhu et al. · 2019 · Journal of Experimental & Clinical Cancer Research
- Palmitoylation restricts SQSTM1/p62-mediated autophagic degradation of NOD2 to modulate inflammationLingli Zhou, Xing He, Liqiu Wang, Ping Wei, Zhe Cai, Song Zhang, Shouheng Jin, Huasong Zeng, Jun Cui · 2022 · Cell Death and Differentiation
- SUMOylation in Viral Replication and Antiviral DefenseYao Fan, Xiang Li, Lei Zhang, Zhi Zong, Fangwei Wang, Jun Huang, Linghui Zeng, Chong Zhang, Haiyan Yan, Long Zhang et al. · 2022 · Advanced Science
- A Type-II Kinase Inhibitor Capable of Inhibiting the T315I “Gatekeeper” Mutant of Bcr-AblHwan Geun Choi, Pingda Ren, Francisco Adrián, Fangxian Sun, Hyun Soo Lee, Xia Wang, Qiang Ding, Guobao Zhang, Yongping Xie, Jianming Zhang et al. · 2010 · Journal of Medicinal Chemistry
- Amyotrophic Lateral Sclerosis: Molecular Mechanisms, Biomarkers, and Therapeutic StrategiesXiaoming Yang, Yanan Ji, Wei Wang, Lilei Zhang, Zehao Chen, Miaomei Yu, Yuntian Shen, Fei Ding, Xiaosong Gu, Hualin Sun · 2021 · Antioxidants
- Proteomics reveals evidence of cross-talk between protein modifications in bacteria: focus on acetylation and phosphorylationBoumediene Soufi, Nelson Cruz Soares, Vaishnavi Ravikumar, Boris Maček · 2012 · Current Opinion in Microbiology
- Expanding Proteome Coverage with Orthogonal-specificity α-Lytic ProteasesJesse G. Meyer, Sangtae Kim, David A. Maltby, Majid Ghassemian, Nuno Bandeira, Elizabeth A. Komives · 2014 · Molecular & Cellular Proteomics
- Impact of fibrinogen carbamylation on fibrin clot formation and stabilityStéphane Jaisson, Philippe Gillery, Carsten Scavenius, Endy Spriet, Anne Nyhaug, Helen Roberts, Iain Chapple, Annelie Hellvard, Nicolas Delaleu, Piotr Mateusz Mydel et al. · 2017 · Thrombosis and Haemostasis
- Protein Carbamylation: Chemistry, Pathophysiological Involvement, and BiomarkersStéphane Jaisson, Christine Piétrement, Philippe Gillery · 2018 · Advances in clinical chemistry
- Erlotinib: an EGF receptor tyrosine kinase inhibitor in non-small-cell lung cancer treatmentClorinda Schettino, Maria Anna Bareschino, Vincenzo Ricci, Fortunato Ciardiello · 2008 · Expert Review of Respiratory Medicine
- PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinomaJianfeng Wang, Chen Wang, Pan Xu, Xiao Li, Yongning Lu, Di Jin, Xiaomao Yin, Hao Jiang, Jing Li Huang, Huan Xiong et al. · 2021 · Theranostics
- DHHC protein family targets different subsets of glioma stem cells in specific nichesXueran Chen, Lei Hu, Haoran Yang, Huihui Ma, Kaiqin Ye, Chenggang Zhao, Zhiyang Zhao, Haiming Dai, Hongzhi Wang, Zhiyou Fang · 2019 · Journal of Experimental & Clinical Cancer Research
- SENP Proteases as Potential Targets for Cancer TherapyPaulina Tokarz, Katarzyna Woźniak · 2021 · Cancers
- TBK1-METTL3 Axis Facilitates Antiviral ImmunityJingxuan Chen, Xuemei Wei, Xiao Wang, Tong Liu, Yingchi Zhao, Luoying Chen, Yujie Luo, Hongqiang Du, Yunfei Li, Tongtong Liu et al. · 2021 · Cell Reports
- One-year follow-up of clinical, metabolic and oxidative stress profile of morbid obese patients after laparoscopic sleeve gastrectomy. 8-oxo-dG as a clinical markerLidia Monzó-Beltrán, Antonio Vázquez Tarragón, Concha Cerdá, Paula García-Pérez, Antonio Iradi, Carlos Sánchez, B. Prats Climent, Carmen Tormos, Antonio Vázquez Prado, Javier Girbés et al. · 2017 · Redox Biology
- Pellino1-mediated TGF-β1 synthesis contributes to mechanical stress induced cardiac fibroblast activationJuan Song, Yun Zhu, Jiantao Li, Jiahao Liu, Yun Gao, Tuanzhu Ha, Linli Que, Li Liu, Guo‐Qing Zhu, Qi Chen et al. · 2014 · Journal of Molecular and Cellular Cardiology
- Chronic Increase of Urea Leads to Carbamylated Proteins Accumulation in Tissues in a Mouse Model of CKDChristine Piétrement, Laëtitia Gorisse, Stéphane Jaisson, Philippe Gillery · 2013 · PLoS ONE
- Osimertinib in T790M-positive and -negative patients with EGFR-mutated advanced non-small cell lung cancer (the TREM-study)Inger Johanne Zwicky Eide, Åslaug Helland, Simon Ekman, Anders Mellemgaard, Karin Holmskov Hansen, Saulius Cicėnas, Jussi Pekka Koivunen, Bjørn Henning Grønberg, Odd Terje Brustugun · 2020 · Lung Cancer
- TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasisQichao Huang, Dan Wu, Jing Zhao, Zeyu Yan, Lin Chen, Shanshan Guo, Dalin Wang, Chong Gang Yuan, Yinping Wang, Xiaoli Liu et al. · 2022 · The EMBO Journal
- Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumorsLaure Voisin, Catherine Julien, Stéphanie Duhamel, Kailesh Gopalbhai, Isabelle Claveau, Marc K. Saba-El-Leil, Ian Gaël Rodrigue‐Gervais, Louis Arthur Gaboury, Daniel Lamarre, Mark Basik et al. · 2008 · BMC Cancer
- Mitochondrial Metabolism Regulates Microtubule Acetylome and Autophagy Trough Sirtuin-2: Impact for Parkinson’s DiseaseA. Raquel Esteves, Daniela M. Arduíno, Diana Filipa Silva, Sofia Viana, Frederico Costa Pereira, Sandra M. Cardoso · 2017 · Molecular Neurobiology
- Depalmitoylation rewires FLT3-ITD signaling and exacerbates leukemia progressionKaosheng Lv, Jian‐Gang Ren, Xu Han, Jun Gui, Chujie Gong, Wei Tong · 2021 · Blood
- Targeting N-myristoylation for therapy of B-cell lymphomasErwan Beauchamp, Megan C. Yap, Aishwarya Iyer, Maneka A. Perinpanayagam, Jay M. Gamma, Krista Marie Vincent, Manikandan Lakshmanan, Anandhkumar Raju, Vinay Tergaonkar, Soo‐Yong Tan et al. · 2020 · Nature Communications
- Intra- and Extra-Cellular Events Related to Altered Glycosylation of MUC1 Promote Chronic Inflammation, Tumor Progression, Invasion, and MetastasisSandra Cascio, Olivera J. Finn · 2016 · Biomolecules
- Customized protein glycosylation to improve biopharmaceutical function and targetingVan Landuyt, Linde, Lonigro, Chiara, Meuris, Leander, Callewaert, Nico · 2019 · Current Opinion in Biotechnology
- Lipoproteins in chronic kidney disease: from bench to bedsideThimoteus Speer, Paul M. Ridker, Arnold von Eckardstein, Stefan J. Schunk, Danilo Fliser · 2020 · European Heart Journal
- Sunitinib in the treatment of renal cell carcinoma: an update on recent evidenceMimma Rizzo, Camillo Porta · 2017 · Therapeutic Advances in Urology
- Protection of cullin–RING E3 ligases by CSN–UBP12June‐Tai Wu, Y. Chan, Cheng‐Ting Chien · 2006 · Trends in Cell Biology
- Suppression of PDGF-induced PI3 kinase activity by imatinib promotes adipogenesis and adiponectin secretionStephen Fitter, Kate Vandyke, Stan Gronthos, Andrew C.W. Zannettino · 2012 · Journal of Molecular Endocrinology
- Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylationHao Cheng, Hongwen Xuan, Christopher D. Green, Yixing Han, Na Sun, Hongjie Shen, Joseph McDermott, David Alan Bennett, Fei Lan, Jing‐Dong J. Han · 2018 · Proceedings of the National Academy of Sciences
- Metabolic reprogramming of ovarian cancer involves ACSL1-mediated metastasis stimulation through upregulated protein myristoylationQingyu Zhang, Wei Zhou, Shan Yu, Yaojun Ju, Sally Kit Yan To, Alice S.T. Wong, Yufei Jiao, Terence Chuen Wai Poon, Kin Yip Tam, Leo Tsz On Lee · 2020 · Oncogene
- The Role of Histone Protein Acetylation in Regulating Endothelial FunctionZhi Hong Fang, Xiang Wang, Xiaoran Sun, Wenquan Hu, Qing Miao · 2021 · Frontiers in Cell and Developmental Biology
- Targeting Pyruvate Kinase M2 Phosphorylation Reverses Aggressive Cancer PhenotypesMaria Apostolidi, Ioannis A. Vathiotis, Viswanathan Muthusamy, Patricia Gaule, Brandon M. Gassaway, David L. Rimm, Jesse Rinehart · 2021 · Cancer Research
- Erdafitinib: A novel therapy for FGFR-mutated urothelial cancerKiera Roubal, Zin War Myint, Jill Kolesar · 2020 · American Journal of Health-System Pharmacy
- Oxidized high-density lipoprotein promotes CD36 palmitoylation and increases lipid uptake in macrophagesYun Zhang, Doudou Dong, Xiaoting Xu, Hui He, Yuan Zhu, Tingwen Lei, Hailong Ou · 2022 · Journal of Biological Chemistry
- S -Nitrosylation: Specificity, Occupancy, and Interaction with Other Post-Translational ModificationsAlicia M. Evangelista, Mark Jeffrey Kohr, Elizabeth Murphy · 2012 · Antioxidants and Redox Signaling
- Super enhancers at the miR-146a and miR-155 genes contribute to self-regulation of inflammationQiong Duan, Xiaoxiao Mao, Yi Xiao, Zhenzhen Liu, Yangui Wang, Haoyang Zhou, Zhengxiang Zhou, Jinxing Cai, Ke Xia, Qubo Zhu et al. · 2016 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- Phosphorylation of αB-crystallin: Role in stress, aging and patho-physiological conditionsBakthisaran Raman, Kranthi Kiran Akula, Tangirala Ramakrishna, Ch. Mohan Rao · 2015 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Metabolism and acetylation in innate immune cell function and fateAlanna M. Cameron, Simon J. Lawless, Edward J. Pearce · 2016 · Seminars in Immunology
- HDAC 2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer's diseaseLaura J. Mahady, M. Nadeem, Michael H. Malek‐Ahmadi, K. Chen, Sylvia E. Perez, Elliott Jay Mufson · 2018 · Neuropathology and Applied Neurobiology
- SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extensionKaiyu Gao, Yi Li, Shumei Hu, Ying Liu · 2019 · eLife
- Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19Tamás Pongrácz, Jan Nouta, Wenjun Wang, Krista E. van Meijgaarden, Federica Linty, Gestur Vidarsson, Simone A. Joosten, Tom H. M. Ottenhoff, Cornelis Hendrik Hokke, Jutte J.C. de Vries et al. · 2022 · EBioMedicine
- Carbamylated Low-Density Lipoproteins Induce a Prothrombotic State Via LOX-1Erik Walter Holy, Alexander Akhmedov, Thimoteus Speer, Giovanni Guido Camici, Stephen Zewinger, Nicole R. Bonetti, Jürg Hans Beer, Thomas Felix Lüscher, Felix Christoph Tanner · 2016 · Journal of the American College of Cardiology
- TCR-induced sumoylation of the kinase PKC-θ controls T cell synapse organization and T cell activationXudong Wang, Yu Gong, Zhi-Long Chen, Bei-Ni Gong, Ji-Ji Xie, Chuan‐Qi Zhong, Qilong Wang, Lianghui Diao, Anlong Xu, Jiahuai Han et al. · 2015 · Nature Immunology
- Phenotypic and genotypic spectrum of congenital disorders of glycosylation type I and type IIAmal M. Al Teneiji, Theodora U. J. Bruun, Sarah Sidky, Dawn Cordeiro, Ronald D. Cohn, Roberto Mendoza‐Londono, Mahendranath D. Moharir, Julian Raiman, Komudi Siriwardena, Lianna G. Kyriakopoulou et al. · 2017 · Molecular Genetics and Metabolism
- Noncoding RNAs involved in DNA methylation and histone methylation, and acetylation in diabetic vascular complicationsJunying Lu, Yuanyuan Huang, Xiaohao Zhang, Yang Xu, Shu Nie · 2021 · Pharmacological Research
- S-Nitrosylation in Alzheimer's diseaseQing‐Fei Zhao, Jin‐Tai Yu, Lan Tan · 2014 · Molecular Neurobiology
- Decreased Mitochondrial Pyruvate Transport Activity in the Diabetic HeartShraddha S. Vadvalkar, Satoshi Matsuzaki, Craig A. Eyster, Jennifer R. Giorgione, Lee Broderick Bockus, Caroline S. Kinter, Michael T Kinter, Kenneth Michael Humphries · 2017 · Journal of Biological Chemistry
- Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathwayChih-Hsing Chou, Miao-Juei Huang, Chi‐Hau Chen, Ming‐Kwang Shyu, John C. Huang, Ji‐Shiang Hung, Chiun‐Sheng Huang, Min‐Chuan Huang · 2015 · Oncotarget
- Bosutinib, dasatinib, imatinib, nilotinib, and ponatinib differentially affect the vascular molecular pathways and functionality of human endothelial cellsAyala Gover‐Proaktor, Galit Granot, Metsada Pasmanik, Oren Pasvolsky, Saar Shapira, Oshrat Raz, Pia Raanani, Avi Leader · 2018 · Leukemia & lymphoma/Leukemia and lymphoma
- RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in MelanomaThibault Houlès, Simon‐Pierre Gravel, Geneviève Lavoie, Sejeong Shin, Mathilde Savall, Antoine Méant, Benoı̂t Grondin, Louis Arthur Gaboury, Sang-Oh Yoon, Julie St‐Pierre et al. · 2018 · Cancer Research
- Metabolomic and microarray analyses of adipose tissue of dapagliflozin-treated mice, and effects of 3-hydroxybutyrate on induction of adiponectin in adipocytesShigeki Nishitani, Atsunori Fukuhara, Jihoon Shin, Yosuke Okuno, Michio Otsuki, Iichiro Shimomura · 2018 · Scientific Reports
- The role of S-nitrosylation of PFKM in regulation of glycolysis in ovarian cancer cellsWenwen Gao, Mengqiu Huang, Xi Chen, Jianping Chen, Zhiwei Zou, Linlin Li, Kaiyuan Ji, Zhirui Nie, Bingsheng Yang, Zibo Wei et al. · 2021 · Cell Death and Disease
- The Crystal Structure of Palmitoyl Protein Thioesterase-2 (PPT2) Reveals the Basis for Divergent Substrate Specificities of the Two Lysosomal Thioesterases, PPT1 and PPT2Guillermo A. Calero, Praveena K. Gupta, Maria Cristina Nonato, Sagun K. Tandel, Edward R. Biehl, Sandra L. Hofmann, Jon Clardy · 2003 · Journal of Biological Chemistry
- Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseasesHiren Jitendra Joshi, Lars Hestbjerg Hansen, Yoshiki Narimatsu, Hudson H. Freeze, Bernard Henrissat, Eric Bennett, Hans Heugh Wandall, Henrik Clausen, Katrine T.-B. G. Schjoldager · 2018 · Glycobiology
- Proteomic research in sarcomas – current status and future opportunitiesJessica Burns, Christopher P. Wilding, Robin L. Jones, Paul H. Huang · 2019 · Seminars in Cancer Biology
- SUMOylation in Neurodegenerative DiseasesAndrea Princz, Nektarios Tavernarakis · 2019 · Gerontology
- Selective HDAC8 Inhibition Attenuates Isoproterenol-Induced Cardiac Hypertrophy and Fibrosis via p38 MAPK PathwayTingwei Zhao, Hae Jin Kee, Liyan Bai, Moon-Ki Kim, Seung‐Jung Kee, Myung Ho Jeong · 2021 · Frontiers in Pharmacology
- ZDHHC22-mediated mTOR palmitoylation restrains breast cancer growth and endocrine therapy resistanceJiefeng Huang, Jie Li, Jun Tang, Yushen Wu, Fengsheng Dai, Ziying Yi, Yan Wang, Yunhai Li, Yue Wu, Guosheng Ren et al. · 2022 · International Journal of Biological Sciences
- Palmitoylation and depalmitoylation defectsThorsten Hornemann · 2014 · Journal of Inherited Metabolic Disease
- An atypical 12q24.31 microdeletion implicates six genes including a histone demethylase KDM2B and a histone methyltransferase SETD1B in syndromic intellectual disabilityLabonne, Jonathan D. J., Lee, Kang-Han, Iwase, Shigeki, Kong, Il-Keun, Diamond, Michael P., Layman, Lawrence C., Kim, Cheol-Hee, Kim, Hyung-Goo · 2016 · Human Genetics
- Structural basis for acyl-group discrimination by human Gcn5L2Alison Epstein Ringel, Cynthia Wolberger · 2016 · Acta Crystallographica Section D Structural Biology
- Phosphorylation of RAB7 by TBK1/IKKϵ Regulates Innate Immune Signaling in Triple-Negative Breast CancerJessica Ritter, Zehua Zhu, Tran Cam Thai, Navin R. Mahadevan, Philipp Mertins, Erik H. Knelson, Brandon P. Piel, Saemi Han, Jacob D. Jaffe, Steven A. Carr et al. · 2019 · Cancer Research
- The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1Kifayat Ullah, Suping Chen, Jiaqi Lü, Xiaohui Wang, Qing Lin Liu, Yang Zhang, Ya‐Qiu Long, Zhanhong Hu, Guoqiang Xu · 2020 · Journal of Biological Chemistry
- Aging alters acetylation status in skeletal and cardiac musclesDongwook Yeo, Chounghun Kang, Li Li Ji · 2020 · GeroScience
- Therapeutic effect of a histone demethylase inhibitor in Parkinson’s diseaseMingdao Mu, Zhong‐Ming Qian, Sheng-Xi Yang, Kang‐Lin Rong, Wing‐Ho Yung, Ya Ke · 2020 · Cell Death and Disease
- Proteogenomic characterization of cholangiocarcinomaMengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan et al. · 2022 · Hepatology
- Ubiquitin sets the timer: impacts on aging and longevityKevei, Éva, Hoppe, Thorsten · 2014 · Nature Structural & Molecular Biology
- The inhibition of antithrombin by peptidylarginine deiminase 4 may contribute to pathogenesis of rheumatoid arthritisXiaotian Chang · 2004 · British journal of rheumatology
- Multilayered N-Glycoproteome Profiling Reveals Highly Heterogeneous and Dysregulated Protein N-Glycosylation Related to Alzheimer’s DiseasePan Fang, Juanjuan Xie, Shaoming Sang, Lei Zhang, Mingqi Liu, Lujie Yang, Yiteng Xu, Guoquan Yan, Jun Hu Yao, Xing Gao et al. · 2019 · Analytical Chemistry
- OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIsWentao Liu, Bin Yan, Haixin Yu, Jiannan Ren, Mou Peng, Liang Zhu, Yinhuai Wang, Xin Jin, Lu Yi · 2022 · International Journal of Biological Sciences
- Modulating epigenetic HAT activity for reinstating acetylation homeostasis: A promising therapeutic strategy for neurological disordersShabir Ahmad Ganai, Shahid Banday, Zeenat Farooq, Mohammad Altaf · 2016 · Pharmacology & Therapeutics
- Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathwayXuemei Chen, Shuai Wang, Ying Zhou, Yanfei Han, Sheng‐Tian Li, Qing Xu, Longyong Xu, Ziqi Zhu, Youming Deng, Lu Yu et al. · 2018 · Nature Communications
- Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's diseaseIsidró Ferrer, Pol Andrés‐Benito, Karina Ausín, Reinald Pamplona, José Antonio del Rı́o, Joaquín Fernández‐Irigoyen, Enrique Santamaría · 2021 · Brain Pathology
- UCHL3 promotes ovarian cancer progression by stabilizing TRAF2 to activate the NF-κB pathwayMinghui Zhang, Huihui Zhang, Xue‐Hua Du, Jie Gao, Chao Li, Hui-Rong Shi, Shangze Li · 2019 · Oncogene
- The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological FunctionTakumi Okamoto, Kazunori Imaizumi, Masayuki Kaneko · 2020 · International Journal of Molecular Sciences
- Differential gene expression signatures between colorectal cancers with and without KRAS mutations: Crosstalk between the KRAS pathway and other signalling pathwaysToshiaki Watanabe, Takashi Kobunai, Yoko Yamamoto, Keiji Matsuda, Soichiro Ishihara, Keijiro Nozawa, Hisae Iinuma, Hiroki Ikeuchi, Kiyoshi Eshima · 2011 · European Journal of Cancer
- CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53‐mediated trans‐repression of β‐secretaseAmir Kumar Singh, Uttam Pati · 2015 · Aging Cell
- Sorafenib in Renal Cell CarcinomaKeith T. Flaherty · 2007 · Clinical Cancer Research
- Trametinib in the treatment of multiple malignancies harboring MEK1 mutationsTong Lian, Changying Li, Haitao Wang · 2019 · Cancer Treatment Reviews
- Autophagy regulation by acetylation—implications for neurodegenerative diseasesSung Min Son, So Jung Park, Marian Fernandez-Estévez, David Chaim Rubinsztein · 2021 · Experimental & Molecular Medicine
- Redox modifications of cysteine residues regulate the cytokine activity of HMGB1Huan Yang, Peter Lundbäck, Lars Ottosson, Helena Erlandsson-Harris, Emilie Vénéreau, Marco Emilio Bianchi, Yousef Al‐Abed, Ulf Andersson, Kevin J. Tracey · 2021 · Molecular Medicine
- Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6Nan Qiu, Daniel Abegg, Mara Guidi, Kerry M. Gilmore, Peter H. Seeberger, Alexander Adibekian · 2021 · Cell chemical biology
- Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's diseaseRobert Nisticò, Caterina Ferraina, Veronica Marconi, Fabio Blandini, Lucia Negri, Jan Egebjerg, Marco Feligioni · 2014 · Frontiers in Pharmacology
- A glycogene mutation map for discovery of diseases of glycosylationLars Hestbjerg Hansen, Allan Lind-Thomsen, Hiren Jitendra Joshi, Nis Borbye‐Lorenzen, Christian Theil Have, Yun Kong, Shengjun Wang, Thomas Sparsø, Niels Grarup, Malene Bech Vester-Christensen et al. · 2014 · Glycobiology
- Differential alkylation-based redox proteomics – Lessons learntKatarzyna Wojdyła, Adelina Rogowska-Wrzesińska · 2015 · Redox Biology
- 6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2Shang-Ju Chuang, Shu‐Chun Cheng, Hui-Chi Tang, Chiao-Yin Sun, Chi‐Yuan Chou · 2018 · Scientific Reports
- PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under HypoxiaQin Zhao, Ke Zheng, Chunmin Ma, Jingjie Li, Lingang Zhuo, Wenhua Huang, Tao Chen, Yuhui Jiang · 2019 · Molecular Cell
- The PSMD14 inhibitor Thiolutin as a novel therapeutic approach for esophageal squamous cell carcinoma through facilitating SNAIL degradationChao Jing, Xingchen Li, Mengqian Zhou, Shengchi Zhang, Qingchuan Lai, Dandan Liu, Beibei Ye, Linqi Li, Yue Wu, Hong Li et al. · 2021 · Theranostics
- Zdhhc13-dependent Drp1 S-palmitoylation impacts brain bioenergetics, anxiety, coordination and motor skillsEleonora Napoli, Gyu‐Yong Song, Siming Liu, Alexsandra B. Espejo, Carlos J. Pérez, Fernando J. Benavides, Cecilia Giulivi · 2017 · Scientific Reports
- Parkin in Parkinson’s Disease and Cancer: a Double-Edged SwordKhushnuma Wahabi, Ahmad Perwez, M. Moshahid A. Rizvi · 2018 · Molecular Neurobiology
- Regulation of Notch Function by O-GlycosylationBeth M. Harvey, Robert S. Haltiwanger · 2018 · Advances in experimental medicine and biology
- The protease activity of human ATG4B is regulated by reversible oxidative modificationXueping Zheng, Zuolong Yang, Qianqian Gu, Fan Xia, Yuanyuan Fu, Peiqing Liu, Xiao‐Ming Yin, Min Li · 2019 · Autophagy
- SUMOylation in development and neurodegenerationTak Yu Yau, Oscar Molina, Albert J. Courey · 2020 · Development
- Endothelial Palmitoylation Cycling Coordinates Vessel Remodeling in Peripheral Artery DiseaseXiaochao Wei, Sangeeta Adak, Mohamed Adel Zayed, Yin Li, Feng Chu, Sarah L. Speck, Rahul S. Kathayat, Qiang Zhang, Bryan C. Dickinson, Clay F. Semenkovich · 2020 · Circulation Research
- Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritisYilin Wang, Aneesah Khan, Aristotelis Antonopoulos, Laura Bouché, Christopher Dominic Buckley, Andrew D. Filer, Karim Raza, Kunping Li, Barbara Tolusso, Elisa Gremese et al. · 2021 · Nature Communications
- Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiologyWejdane El Manaa, Eric Duplan, Thomas Goiran, Inger Lauritzen, Loan Vaillant-Beuchot, Sandra Lacas‐Gervais, Vanessa A. Morais, Han You, Ling Qi, Mario Salazar et al. · 2021 · Autophagy
- Targeting epigenetic modulators using PROTAC degraders: Current status and future perspectiveThomas Webb, Conner Craigon, Alessio Ciulli · 2022 · Bioorganic & Medicinal Chemistry Letters
- O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylationLorela Ciraku, Zachary A. Bacigalupa, Jing Ju, Rebecca A. Moeller, Giang Le Minh, Rusia H. Lee, Michael D. Smith, Christina M. Ferrer, Sophie Trefely, Luke Izzo et al. · 2022 · Oncogene
- SUMOylation pathway alteration coupled with downregulation of SUMO E2 enzyme at mucosal epithelium modulates inflammation in inflammatory bowel diseaseSalman Ahmad Mustfa, Mukesh Kumar Singh, Aamir Suhail, Gayatree Mohapatra, Smriti Verma, Debangana Chakravorty, Sarika Rana, Ritika Rampal, Atika Dhar, Sudipto Saha et al. · 2017 · Open Biology
- ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphomaAgnieszka Dzikiewicz‐Krawczyk, K Kok, Izabella Ślęzak-Prochazka, Jan Lukas Robertus, Jan Bruining, Mina Masoumeh Tayari, Bea Rutgers, Debora de Jong, Jasper A. Koerts, A Seitz et al. · 2017 · Leukemia
- MicroRNA-574-5p promotes cell growth of vascular smooth muscle cells in the progression of coronary artery diseaseZhongmeng Lai, Pengtao Lin, Xianfeng Weng, Jiansheng Su, Ye Chen, Ying He, Guohua Wu, Jiebo Wang, Ying Yu, Liangcheng Zhang · 2017 · Biomedicine & Pharmacotherapy
- Palmitoylation of SARS‐CoV‐2 S protein is critical for S‐mediated syncytia formation and virus entryDaoqun Li, Yihan Liu, Yue Lu, Shan Gao, Leiliang Zhang · 2021 · Journal of Medical Virology
- NADPH oxidase 4 and endothelial nitric oxide synthase contribute to endothelial dysfunction mediated by histone methylations in metabolic memoryYunfei Liao, Luoning Gou, Lulu Chen, Xueyu Zhong, Dongxue Zhang, Han-gang Zhu, Xiaodan Lü, Tianshu Zeng, Xiu‐Ling Deng, Yuming Li · 2017 · Free Radical Biology and Medicine
- GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient miceWei Yuan, Liaoxun Lu, Muding Rao, Yang Huang, Chun-E Liu, Shuang Liu, Yue Zhao, Huicong Liu, Jiangli Zhu, Tianzhu Chao et al. · 2021 · Proceedings of the National Academy of Sciences
- Myristoylation-mediated phase separation of EZH2 compartmentalizes STAT3 to promote lung cancer growthJie Zhang, Yuanyuan Zeng, Yueping Xing, Xiangrong Li, Lingqin Zhou, Lin Tao Hu, Yue Eugene Chin, Meng Wu · 2021 · Cancer Letters
- Protein methylation in mitochondriaJędrzej Małecki, Erna Davydova, Pål Ø. Falnes · 2022 · Journal of Biological Chemistry
- Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylationMinle Li, Xue Zhao, Hongmei Yong, Jian Xu, Pengfei Qu, Shuxi Qiao, Pingfu Hou, Zhongwei Li, Sufang Chu, Junnian Zheng et al. · 2022 · Cell Death and Disease
- AKT2 phosphorylation of hexokinase 2 at T473 promotes tumorigenesis and metastasis in colon cancer cells via NF-κB, HIF1α, MMP2, and MMP9 upregulationHang Li, Shaohong Lu, Yu Chen, Long‐Zhi Zheng, Liangyuan Chen, Haojie Ding, Jianzu Ding, Di Lou, Fangfang Liu, Bin Zheng · 2019 · Cellular Signalling
- N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signalsXiuping Huang, Qing Ye, Min Chen, Aimin Li, Wenting Mi, Yuxin Fang, Yekaterina Y. Zaytseva, Kathleen L. O’Connor, Craig W. Vander Kooi, Side Liu et al. · 2019 · Nature Communications
- Metabolism of short‐chain fatty acid propionate induces surface expression of NKG2D ligands on cancer cellsHøgh, Rikke Illum, Møller, Sofie Hedlund, Jepsen, Stine Dam, Mellergaard, Maiken, Lund, Astrid, Pejtersen, Mikala, Fitzner, Emil, Andresen, Lars, Skov, Søren · 2020 · The FASEB Journal
- Cabozantinib: an Active Novel Multikinase Inhibitor in Renal Cell CarcinomaNizar M. Tannir, Gisela M. Schwab, Viktor Grünwald · 2017 · Current Oncology Reports
- Disease-Linked Glutarylation Impairs Function and Interactions of Mitochondrial Proteins and Contributes to Mitochondrial HeterogeneityJessica Schmiesing, Stephan Storch, Ann-Cathrin Dörfler, Michaela Schweizer, Georgia Makrypidi‐Fraune, Melanie Thelen, Marc Sylvester, Volkmar Gieselmann, Catherine Meyer‐Schwesinger, Friedrich Koch‐Nolte et al. · 2018 · Cell Reports
- Impact of Posttranslational Modification in Pathogenesis of Rheumatoid Arthritis: Focusing on Citrullination, Carbamylation, and AcetylationEui-Jong Kwon, Ji Hyeon Ju · 2021 · International Journal of Molecular Sciences
- Recent advances in top‐down proteome sample processing ahead of MS analysisJessica L. Nickerson, Venus Baghalabadi, Subin R. C. K. Rajendran, Philip J. Jakubec, Hammam Said, Teresa S. McMillen, Ziheng Dang, Alan Austin Doucette · 2021 · Mass Spectrometry Reviews
- Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified PeptidesRajan A. Burt, Borislav Dejanovic, Hayley J. Peckham, Kimberly A. Lee, Xiang Li, Johain R. Ounadjela, Anjana Rao, Stacy Alyse Malaker, Steven A. Carr, Samuel A. Myers · 2021 · Molecular & Cellular Proteomics
- Lysine acetylation in the lumen of the ER: A novel and essential function under the control of the UPRMariana Pehar, Luigi Puglielli · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseasesShi Biao Chia, Evan A. Elko, Reem Aboushousha, Allison M. Manuel, Cheryl van de Wetering, Joseph E. Druso, Jos L. J. van der Velden, David Joseph Seward, Vikas Anathy, Charles G. Irvin et al. · 2019 · American Journal of Physiology-Cell Physiology
- Salt-inducible kinase 1 maintains HDAC7 stability to promote pathologic cardiac remodelingAustin Hsu, Qiming Duan, Sarah McMahon, Yu Huang, Sarah A.B. Wood, Nathanael S. Gray, Biao Wang, Benoit G. Bruneau, Saptarsi M. Haldar · 2020 · Journal of Clinical Investigation
- Acalabrutinib: A Selective Bruton Tyrosine Kinase Inhibitor for the Treatment of B-Cell MalignanciesHussein A. Abbas, William G. Wierda · 2021 · Frontiers in Oncology
- The Function and related Diseases of Protein CrotonylationShuo Wang, Guanqun Mu, Bingquan Qiu, Meng Wang, Zunbo Yu, Weibin Wang, Jiadong Wang, Yang Yang · 2021 · International Journal of Biological Sciences
- Proteomics: Bases for protein complexity understandingDomenico Rotilio, Anna Della Corte, Marco D’Imperio, Walter Coletta, Simone Marcone, Cristian Silvestri, Lucia Giordano, Michela Di Michele, Maria Benedetta Donati · 2012 · Thrombosis Research
- The roles of PAD2 ‐ and PAD4 ‐mediated protein citrullination catalysis in cancersYanbin Wang, Riping Chen, Yihan Gan, Shibo Ying · 2020 · International Journal of Cancer
- Extraintestinal Manifestations in Patients with Inflammatory Bowel Disease: Study Based on the ENEIDA RegistryAlicia Algaba, Iván Guerra, Elena Ricart, Eva Lorenzo Iglesias, Míriam Mañosa, Javier P. Gisbert, Jordi Guardiola, Miguel Mínguez, Beatriz Castro, Ruth de Francisco et al. · 2020 · Digestive Diseases and Sciences
- KNSTRN promotes tumorigenesis and gemcitabine resistance by activating AKT in bladder cancerYaoyi Xiong, Lingao Ju, Lushun Yuan, Liang Chen, Gang Wang, Huimin Xu, Tianchen Peng, Yongwen Luo, Yu Xiao, Xinghuan Wang · 2021 · Oncogene
- Strategies for Glycoengineering Therapeutic ProteinsKris Dammen-Brower, Paige Epler, Stanley Zhu, Zachary J. Bernstein, P. Stabach, D. Braddock, Jamie B. Spangler, K. Yarema · 2022 · Frontiers in Chemistry
- Sodium Benzoate–Rich Beverage Consumption is Associated With Increased Reporting of ADHD Symptoms in College StudentsBonnie Beezhold, Carol S. Johnston, Kathleen A. Nochta · 2012 · Journal of Attention Disorders
- Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120Jason Yolitz, Catherine Schwing, Julia Chang, Donald Van Ryk, Fatima Nawaz, Danlan Wei, Claudia Cicala, James A. Arthos, Anthony S. Fauci · 2018 · Proceedings of the National Academy of Sciences
- HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical DevelopmentTianxiang Tang, Yandong Zhang, Yafei Wang, Zheping Cai, Zhiheng Lu, Leiting Li, Ru Huang, Astrid Hagelkrüys, Patrick Matthias, Heng Zhang et al. · 2019 · Neuron
- Histone Mono-Ubiquitination in Transcriptional Regulation and Its Mark on Life: Emerging Roles in Tissue Development and DiseaseLiat Oss-Ronen, Tzlil Sarusi, Idan Cohen · 2022 · Cells