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Functional anatomy of the basal ganglia

Yelnik, J.·2002·Movement Disorders

Abstract

Four organizational levels of the basal ganglia that could be particularly determinant in terms of functional properties are reviewed: (1) macroscopic anatomy, which is characterized by a dramatic decrease of cerebral tissue volume from the cerebral cortex to the deepest portions of the basal ganglia; (2) connectivity, which consists of both complex loops and a partition into three territories, sensorimotor, associative, and limbic (which process motor, cognitive, and emotional information, respectively); (3) neuronal morphology, characterized by a dramatic numeric and geometric convergence of striatal neurons onto pallidonigral neurons; and (4) dopaminergic innervation of the basal ganglia, which is organized as a dual system that is supposed to have opposite effects on the activity of the system. Current models of the basal ganglia are discussed.

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Metadata

Authors
Yelnik, J.
Venue
Movement Disorders
Publisher
Wiley
Published
2002-03
Volume
17
Issue
S3
Pages
S15-S21
ISSN
  • 0885-3185 (ISSN-L)
  • 1531-8257
OpenAlex
W2156969587
Cited by
952
References
6
FWCI
38.30
Type
journal article
Language
en
Open access
closed
Licence
doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 4932 d)

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