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The effectiveness of exercise interventions for people with Parkinson's disease: A systematic review and meta‐analysis
Open accessAbstract
Parkinson's disease (PD) is a neurodegenerative disorder affecting the physical, psychological, social, and functional status of individuals. Exercise programs may be an effective strategy to delay or reverse functional decline for people with PD and a large body of empirical evidence has emerged in recent years. The objective is to systematically review randomized controlled trials (RCTs) reporting on the effectiveness of exercise interventions on outcomes (physical, psychological or social functioning, or quality of life) for people with PD. RCTs meeting the inclusion criteria were identified by systematic searching of electronic databases. Key data were extracted by two independent researchers. A mixed methods approach was undertaken using narrative, vote counting, and random effects meta-analysis methods. Fourteen RCTs were included and the methodological quality of most studies was moderate. Evidence supported exercise as being beneficial with regards to physical functioning, health-related quality of life, strength, balance and gait speed for people with PD. There was insufficient evidence support or refute the value of exercise in reducing falls or depression. This review found evidence of the potential benefits of exercise for people with PD, although further good quality research is needed. Questions remain around the optimal content of exercise interventions (dosing, component exercises) at different stages of the disease.
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“Prior research has shown significant improvements in aerobic capacity (Schenkman et al., 2012) and muscle strength (Goodwin et al., 2008; Mehrholz et al., 2010), in persons with PD following exercise training.”
From Perception of Physical Demand, Mental Demand, and Performance: A Comparison of Two Voice Interventions for Parkinson's Disease (2022) · cites this paper as Goodwin et al., 2008
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Metadata
- Authors
- Goodwin, V. A., Richards, S. H., Taylor, R. S., Taylor, A. H., & Campbell, J. L.
- Affiliations
- University of Exeter (GB)
- Corresponding author
- Goodwin, Victoria A.
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2008-01-07
- Volume
- 23
- Issue
- 5
- Pages
- 631-640
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W1986148405
- Cited by
- 922
- References
- 48
- Citations by year
- 2026: 31 · 2025: 29 · 2024: 47 · 2023: 31 · 2022: 53 · 2021: 61 · 2020: 51 · 2019: 62 · 2018: 48 · 2017: 45 · 2016: 62 · 2015: 59 · 2014: 58 · 2013: 79 · 2012: 58
- FWCI
- 6.92
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Movement Disorders (publishedVersion)
- PubMed (publishedVersion)
- ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
- Figshare (submittedVersion)
- NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
- Open Research Exeter (University of Exeter) (submittedVersion)
- Funders
- Clinical Academic Fellowship Scheme funded by Devon and Cornwall Workforce Development Confederation
- Plymouth Teaching Primary Care Trust
- Personal Award Scheme Researcher Development Award from the National Institute of Health Research
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Keywords
- Parkinson's disease, exercise intervention, physical function, health-related quality of life, balance, walking speed, muscle strength, falls, depression, functional decline
- MeSH terms
- Postural Balance, Exercise Therapy, Humans, Motor Activity, Parkinson Disease, Quality of Life, Randomized Controlled Trials as Topic, Treatment Outcome
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