The DOI matches its Crossref record; 129 of the 129 references it cites were found in a registry or an index.
Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae
Abstract
The ketocarotenoid astaxanthin can be found in the microalgae Haematococcus pluvialis, Chlorella zofingiensis, and Chlorococcum sp., and the red yeast Phaffia rhodozyma. The microalga H. pluvialis has the highest capacity to accumulate astaxanthin up to 4-5% of cell dry weight. Astaxanthin has been attributed with extraordinary potential for protecting the organism against a wide range of diseases, and has considerable potential and promising applications in human health. Numerous studies have shown that astaxanthin has potential health-promoting effects in the prevention and treatment of various diseases, such as cancers, chronic inflammatory diseases, metabolic syndrome, diabetes, diabetic nephropathy, cardiovascular diseases, gastrointestinal diseases, liver diseases, neurodegenerative diseases, eye diseases, skin diseases, exercise-induced fatigue, male infertility, and HgCl₂-induced acute renal failure. In this article, the currently available scientific literature regarding the most significant activities of astaxanthin is reviewed.
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“Many studies have shown that astaxanthin has protective effects against diseases, such as cancers, inflammatory diseases, metabolic syndrome, diabetes, diabetic nephropathy, neurodegenerative diseases and eye diseases (Yuan et al., 2011).”
From Microalgae Metabolites: A Rich Source for Food and Medicine (2019) · cites this paper as Yuan et al., 2011
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Cites
Astaxanthin: a review of its chemistry and applications
Higuera-Ciapara, I., Félix-Valenzuela, L., & Goycoolea, F. M. (2006) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408690590957188 · Cited by 1,287
Commercial potential for Haematococcus microalgae as a natural source of astaxanthin
Lorenz, R. T., & Cysewski, G. R. (2000) · Trends in biotechnology · doi:10.1016/s0167-7799(00)01433-5 · Cited by 1,190
Antioxidant Activities of Astaxanthin and Related Carotenoids
Naguib, Y. M. A. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf991106k · Cited by 975
Carotenoid Action on the Immune Response
Chew, B. P., & Park, J. S. (2004) · Journal of Nutrition · doi:10.1093/jn/134.1.257s · Cited by 795
Astaxanthin, a Carotenoid with Potential in Human Health and Nutrition
Hussein, G. M. E., Sankawa, U., Goto, H., Matsumoto, K., & Watanabe, H. (2005) · Journal of Natural Products · doi:10.1021/np050354+ · Cited by 653
Carotenogenesis in the green alga Haematococcus pluvialis : Cellular physiology and stress response
Boussiba, S. (2000) · Physiologia Plantarum · doi:10.1034/j.1399-3054.2000.108002111.x · Cited by 591
Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans
Park, J. S., Chyun, J. H., Kim, Y. K., Line, L. L., & Chew, B. P. (2010) · Nutrition & Metabolism · doi:10.1186/1743-7075-7-18 · Cited by 569
Astaxanthin from Microbial Sources
Johnson, E. A., & An, G.-H. (1991) · Critical Reviews in Biotechnology · doi:10.3109/07388559109040622 · Cited by 509
Pashkow, F. J., Watumull, D. G., & Campbell, C. L. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.02.010 · Cited by 455
Goto, S., Kogure, K., Abe, K., Kimata, Y., Kitahama, K., Yamashita, E., & Terada, H. (2001) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(01)00326-1 · Cited by 357
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Ambati, R., Phang, S. M., Ravi, S., & Ravishankar, G. A. (2014) · Marine Drugs · doi:10.3390/md12010128 · Cited by 2,026
Shah, M. M. R., Liang, Y., Cheng, J. J., & Daroch, M. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00531 · Cited by 940
Microalgae Metabolites: A Rich Source for Food and Medicine
Sathasivam, R., Radhakrishnan, R., Hashem, A., & Abd_Allah, E. F. (2019) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2017.11.003 · Cited by 872
Markou, G., & Nerantzis, E. (2013) · Biotechnology Advances · doi:10.1016/j.biotechadv.2013.07.011 · Cited by 815
Saini, R. K., Nile, S. H., & Park, S. W. (2015) · Food Research International · doi:10.1016/j.foodres.2015.07.047 · Cited by 789
Metadata
- Authors
- Yuan, J., Peng, J., Yin, K., & Wang, J.
- Affiliations
- Sun Yat-sen University (CN)
- Corresponding author
- Yuan, Jian‐Ping
- Venue
- Molecular Nutrition & Food Research
- Publisher
- Wiley
- Published
- 2010-11-18
- Volume
- 55
- Issue
- 1
- Pages
- 150-165
- ISSN
- 1613-4125 (ISSN-L)
- 1613-4133
- OpenAlex
- W1988895856
- Cited by
- 649
- References
- 129
- Citations by year
- 2026: 23 · 2025: 44 · 2024: 45 · 2023: 44 · 2022: 55 · 2021: 70 · 2020: 70 · 2019: 47 · 2018: 44 · 2017: 37 · 2016: 34 · 2015: 39 · 2014: 34 · 2013: 25 · 2012: 27
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Molecular Nutrition & Food Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Science and Technology Planning Project of Guangdong Province, China (2007B020708003)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Keywords
- astaxanthin, ketocarotenoids, microalgae, Haematococcus pluvialis, Chlorella zofingiensis, Chlorococcum, Phaffia rhodozyma, health-promoting properties, anticancer activity, anti-inflammatory activity, metabolic syndrome, diabetes mellitus, diabetic nephropathy, cardiovascular disease, neurodegenerative diseases, eye diseases, skin diseases, exercise fatigue, male infertility
- MeSH terms
- Chlorophyta, Anti-Inflammatory Agents, Antineoplastic Agents, Antioxidants, Cardiovascular Agents, Chronic Disease, Humans, Hypoglycemic Agents, Neuroprotective Agents, Xanthophylls, Microalgae
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