Cited by 649Antioxidant Activity and Oxidative StressSeaweed-derived Bioactive CompoundsFatty Acid Research and Health

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Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae

Yuan, Jian‐Ping, Peng, Juan, Yin, Kai, Wang, Jiang‐Hai·2011·Molecular Nutrition & Food Research

DOI 10.1002/mnfr.201000414

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Abstract

The ketocarotenoid astaxanthin can be found in the microalgae Haematococcus pluvialis, Chlorella zofingiensis, and Chlorococcum sp., and the red yeast Phaffia rhodozyma. The microalga H. pluvialis has the highest capacity to accumulate astaxanthin up to 4-5% of cell dry weight. Astaxanthin has been attributed with extraordinary potential for protecting the organism against a wide range of diseases, and has considerable potential and promising applications in human health. Numerous studies have shown that astaxanthin has potential health-promoting effects in the prevention and treatment of various diseases, such as cancers, chronic inflammatory diseases, metabolic syndrome, diabetes, diabetic nephropathy, cardiovascular diseases, gastrointestinal diseases, liver diseases, neurodegenerative diseases, eye diseases, skin diseases, exercise-induced fatigue, male infertility, and HgCl₂-induced acute renal failure. In this article, the currently available scientific literature regarding the most significant activities of astaxanthin is reviewed.

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Authors: Yuan, J., Peng, J., Yin, K., & Wang, J.
Affiliations: Sun Yat-sen University (CN)
Corresponding author: Yuan, Jian‐Ping
ORCID: Yuan, Jian‐Ping
Peng, Juan
Venue: Molecular Nutrition & Food Research
Publisher: Wiley
Published: 2010-11-18
Volume: 55
Issue: 1
Pages: 150-165
ISSN: 1613-4125 (ISSN-L)
1613-4133
DOI: 10.1002/mnfr.201000414
OpenAlex: W1988895856
Cited by: 649
References: 129
Citations by year: 2026: 23 · 2025: 44 · 2024: 45 · 2023: 44 · 2022: 55 · 2021: 70 · 2020: 70 · 2019: 47 · 2018: 44 · 2017: 37 · 2016: 34 · 2015: 39 · 2014: 34 · 2013: 25 · 2012: 27
FWCI: 1.77
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Molecular Nutrition & Food Research (publishedVersion)
PubMed (publishedVersion)
Funders: Science and Technology Planning Project of Guangdong Province, China (2007B020708003)
Topics: Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
Keywords: astaxanthin, ketocarotenoids, microalgae, Haematococcus pluvialis, Chlorella zofingiensis, Chlorococcum, Phaffia rhodozyma, health-promoting properties, anticancer activity, anti-inflammatory activity, metabolic syndrome, diabetes mellitus, diabetic nephropathy, cardiovascular disease, neurodegenerative diseases, eye diseases, skin diseases, exercise fatigue, male infertility
MeSH terms: Chlorophyta, Anti-Inflammatory Agents, Antineoplastic Agents, Antioxidants, Cardiovascular Agents, Chronic Disease, Humans, Hypoglycemic Agents, Neuroprotective Agents, Xanthophylls, Microalgae

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Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae

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