Runnin' with the Dvl: Proteins That Associate with Dsh/Dvl and Their Significance to Wnt Signal Transduction

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Morin, P. J., Sparks, A. B., Kořínek, V., Barker, N., Clevers, H. C., Vogelstein, B., & Kinzler, K. W. (1997) · Science · doi:10.1126/science.275.5307.1787 · Cited by 4,000

Wnt signaling and cancer

Polakis, P. (2000) · Genes & Development · doi:10.1101/gad.14.15.1837 · Cited by 3,183

β‐catenin is a target for the ubiquitin–proteasome pathway

Aberle, H., Bauer, A., Stappert, J., Kispert, A., & Kemler, R. (1997) · The EMBO Journal · doi:10.1093/emboj/16.13.3797 · Cited by 2,586

Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism

Liu, C., Li, Y., Semënov, M. V., Han, C., Baeg, G., Tan, Y., Zhang, Z., Lin, X., & He, X. (2002) · Cell · doi:10.1016/s0092-8674(02)00685-2 · Cited by 2,152

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

N�sslein-Volhard, C., Wieschaus, E. F., & Kluding, H. (1984) · Development Genes and Evolution · doi:10.1007/bf00848156 · Cited by 1,552

A new member of the frizzled family from Drosophila functions as a Wingless receptor

Bhanot, P., van den Brink, M. R. M., Samos, C. H., Hsieh, J.-C., Wang, Y., Macke, J. P., Andrew, D. J., Nathans, J., & Nusse, R. (1996) · Nature · doi:10.1038/382225a0 · Cited by 1,504

Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly

Rubinfeld, B., Albert, I., Porfiri, E., Fiol, C. J., Munemitsu, S. M., & Polakis, P. G. (1996) · Science · doi:10.1126/science.272.5264.1023 · Cited by 1,420

Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β

Behrens, J., Jerchow, B., Würtele, M., Grimm, J., Asbrand, C., Wirtz, R. M., Kühl, M., Wedlich, D., & Birchmeier, W. (1998) · Science · doi:10.1126/science.280.5363.596 · Cited by 1,255

Wnt Signaling in Oncogenesis and Embryogenesis--a Look Outside the Nucleus

Peifer, M., & Polakis, P. (2000) · Science · doi:10.1126/science.287.5458.1606 · Cited by 1,253

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK‐3β and β‐catenin and promotes GSK‐3β‐dependent phosphorylation of β‐catenin

Ikeda, S., Kishida, S., Yamamoto, H., Murai, H., Koyama, S., & Kikuchi, A. (1998) · The EMBO Journal · doi:10.1093/emboj/17.5.1371 · Cited by 1,248

Myristoylated Naked2 escorts transforming growth factor α to the basolateral plasma membrane of polarized epithelial cells

Li, C., Franklin, J. L., Graves‐Deal, R., Jerome, W. G., Cao, Z., & Coffey, R. J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401294101 · Cited by 73

Functional Consequences of Wnt-induced Dishevelled 2 Phosphorylation in Canonical and Noncanonical Wnt Signaling

González‐Sancho, J. M., Greer, Y. E., Abrahams, C. L., Takigawa, Y., Baljinnyam, B., Lee, K. H., Lee, K. S., Rubin, J. S., & Brown, A. M. C. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.448480 · Cited by 71

The Wnt-dependent signaling pathways as target in oncology drug discovery

Janssens, N., Janicot, M., & Perera, T. (2006) · Investigational New Drugs · doi:10.1007/s10637-005-5199-4 · Cited by 73

The involvement of Frodo in TCF-dependent signaling and neural tissue development

Hikasa, H., & Sokol, S. Y. (2004) · Development · doi:10.1242/dev.01369 · Cited by 73

Three Dact gene family members are expressed during embryonic development and in the adult brains of mice

Fisher, D. A. C., Kivimäe, S., Hoshino, J., Suriben, R., Martin, P., Baxter, N., & Cheyette, B. N. R. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20917 · Cited by 72

LET-99, GOA-1/GPA-16, and GPR-1/2 Are Required for Aster-Positioned Cytokinesis

Bringmann, H., Cowan, C. R., Kong, J., & Hyman, A. A. (2006) · Current Biology · doi:10.1016/j.cub.2006.11.070 · Cited by 72

Activation of the non-canonical Dvl–Rac1–JNK pathway by Frizzled homologue 10 in human synovial sarcoma

Fukukawa, C., Nagayama, S., Tsunoda, T., Toguchida, J., Nakamura, Y., & Katagiri, T. (2009) · Oncogene · doi:10.1038/onc.2008.467 · Cited by 73

Diversin regulates heart formation and gastrulation movements in development

Moeller, H., Jenny, A., Schaeffer, H. J., Schwarz, T., Mlodzik, M., Hammerschmidt, M., & Birchmeier, W. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603808103 · Cited by 71

Essential role for β‐arrestin 2 in the regulation of Xenopus convergent extension movements

Kim, G., & Han, J. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601688 · Cited by 66

Crosstalk of the Wnt/β-catenin pathway with other pathways in cancer cells

Morris, S.-A., & Huang, S.-Y. (2016) · Genes and Diseases · doi:10.1016/j.gendis.2015.12.003 · Cited by 72

Interaction between the internal motif KTXXXI of Idax and mDvl PDZ domain

London, T. B. C., Lee, H., Shao, Y., & Zheng, J. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.07.113 · Cited by 68

Dishevelled family proteins are expressed in non-small cell lung cancer and function differentially on tumor progression

Wei, Q., Zhao, Y., Yang, Z., Dong, Q., Dong, X.-J., Han, Y., Chen, Z., & Wang, E. (2008) · Lung Cancer · doi:10.1016/j.lungcan.2008.06.018 · Cited by 65

Adipogenesis: Usefulness of in vitro and in vivo experimental models1,2

NOVAKOFSKI, J. E. (2004) · Journal of Animal Science · doi:10.2527/2004.823905x · Cited by 66

The Role of Wnt Signaling In Cancer and Stem Cells

Reguart, N., He, B., Tarón, M., You, L., Jablons, D. M., & Rosell, R. (2005) · Future Oncology · doi:10.2217/14796694.1.6.787 · Cited by 66

Wnt Signaling in Stem Cells and Non–Small-Cell Lung Cancer

He, B., Barg, R. N., You, L., Xu, Z., Reguart, N., Mikami, I., Batra, S., Rosell, R., & Jablons, D. M. (2005) · Clinical Lung Cancer · doi:10.3816/clc.2005.n.022 · Cited by 63

Apical–basal polarity, Wnt signaling and vertebrate organogenesis

Karner, C. M., Wharton, K. A., & Carroll, T. J. (2006) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2006.05.007 · Cited by 61

Conformational change of Dishevelled plays a key regulatory role in the Wnt signaling pathways

Lee, H., Shi, D., & Zheng, J. (2015) · eLife · doi:10.7554/elife.08142 · Cited by 57

Modulation of GSK-3β/β-Catenin Signaling Contributes to Learning and Memory Impairment in a Rat Model of Depression

Hui, J., Zhang, J., Pu, M., Zhou, X., Dong, L., Mao, X., Shi, G., Zou, J., Wu, J., Jiang, D., et al. (2018) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyy040 · Cited by 62

The enhanced effect of lupeol on the destruction of gastric cancer cells by NK cells

Wu, X., Liu, J., Lu, X., Chen, F., Zhou, Z.-H., Wang, T., Zhu, S.-P., & Fei, S. (2013) · International Immunopharmacology · doi:10.1016/j.intimp.2013.04.017 · Cited by 59

Frizzled 7 Expression Is Positively Regulated by SIRT1 and β-Catenin in Breast Cancer Cells

Simmons, G. E., Jr., Pandey, S., Nedeljkovic-Kurepa, A., Saxena, M., Wang, A., & Pruitt, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098861 · Cited by 59

Frequent amplifications and abundant expression ofTRIO,NKD2, andIRX2 in soft tissue sarcomas

Adamowicz, M. J., Radlwimmer, B., Rieker, R. J., Mertens, D., Schwarzbach, M., Schraml, P., Benner, A., Lichter, P., Mechtersheimer, G., & Joos, S. (2006) · Genes Chromosomes and Cancer · doi:10.1002/gcc.20343 · Cited by 59

XRab40 and XCullin5 form a ubiquitin ligase complex essential for the noncanonical Wnt pathway

Lee, R. H. K., Iioka, H., Ohashi, M., Iemura, S., Natsume, T., & Kinoshita, N. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601781 · Cited by 60

Sonic hedgehog, Wnt, and brain‐derived neurotrophic factor cell signaling pathway crosstalk: potential therapy for depression

Tayyab, M., Shahi, M. H., Farheen, S., M., M. M. P., Khanam, N., Castresana, J. S., & Hossain, M. S. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.24104 · Cited by 59

Abundance, complexation, and trafficking of Wnt/β-catenin signaling elements in response to Wnt3a

Yokoyama, N. N., Yin, D., & Malbon, C. C. (2007) · Journal of Molecular Signaling · doi:10.1186/1750-2187-2-11 · Cited by 60

Lung Epithelial Cells Induce Endodermal Differentiation in Mouse Mesenchymal Bone Marrow Stem Cells by Paracrine Mechanism

Popov, B. V., Serikov, V. B., Ns, P., Izusova, T. V., Gupta, N., & Matthay, M. A. (2007) · Tissue Engineering · doi:10.1089/ten.2007.0001 · Cited by 55

The importance of WNT pathways for bone metabolism and their regulation by implant topography

Galli, C., Piemontese, M., Lumetti, S., Manfredi, E., Gm, M., & Passeri, G. (2012) · European Cells and Materials · doi:10.22203/ecm.v024a04 · Cited by 55

The cellular story of dishevelleds

Kafka, A., Bašić‐Kinda, S., & Pećina‐Šlaus, N. (2014) · Croatian Medical Journal · doi:10.3325/cmj.2014.55.459 · Cited by 53

GABARAPL1 Negatively Regulates Wnt/β-catenin Signaling by Mediating Dvl2 Degradation through the Autophagy Pathway

Zhang, Y., Wang, F., Han, L., Wu, Y., Li, S., Yang, X., Wang, Y., Ren, F., Zhai, Y., Wang, D., et al. (2011) · Cellular Physiology and Biochemistry · doi:10.1159/000329952 · Cited by 59

Retrograde signalling at the synapse: a role for Wnt proteins

Salinas, P. C. (2005) · Biochemical Society Transactions · doi:10.1042/bst0331295 · Cited by 51

A putative novel protein, DEPDC1B, is overexpressed in oral cancer patients, and enhanced anchorage-independent growth in oral cancer cells that is mediated by Rac1 and ERK

Su, Y.-F., Liang, C.-Y., Huang, C., Peng, C.-Y., Chen, C. C., Lin, M.-C., Lin, R., Lin, W., Chou, M., Liao, P.-H., et al. (2014) · Journal of Biomedical Science · doi:10.1186/s12929-014-0067-1 · Cited by 50

WNT Signaling in Hematological Malignancies

Frenquelli, M., & Tonon, G. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.615190 · Cited by 49

Apoptosis associated with Wnt/β-catenin pathway leads to steroid-induced avascular necrosis of femoral head

Zhang, C., Zou, Y., Ma, J., Dang, X., & Wang, K. (2015) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-015-0606-2 · Cited by 49

Dishevelled-2 docks and activates Src in a Wnt-dependent manner

Yokoyama, N. N., & Malbon, C. C. (2009) · Journal of Cell Science · doi:10.1242/jcs.051847 · Cited by 49

Down-regulation of NKD1 increases the invasive potential of non-small-cell lung cancer and correlates with a poor prognosis

Zhang, S., Wang, Y., Dai, S., & Wang, E. (2011) · BMC Cancer · doi:10.1186/1471-2407-11-186 · Cited by 48

Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity–signaling pathway

Guillabert-Gourgues, A., Jaspard‐Vinassa, B., Bats, M., Sewduth, R. N., Franzl, N., Peghaire, C. R., Jeanningros, S., Moreau, C., Roux, É., Larrieu-Lahargue, F., et al. (2016) · Molecular Biology of the Cell · doi:10.1091/mbc.e14-08-1332 · Cited by 50

Regulation of actin cytoskeleton architecture by Eps8 and Abi1

Roffers‐Agarwal, J., Xanthos, J. B., & Miller, J. R. (2005) · BMC Cell Biology · doi:10.1186/1471-2121-6-36 · Cited by 47

Naked1 Antagonizes Wnt Signaling by Preventing Nuclear Accumulation of β-Catenin

Raay, T. J. V., Fortino, N. J., Miller, B. W., Ma, H., Lau, G., Li, C., Franklin, J. L., Attisano, L., Solnica‐Krezel, L., & Coffey, R. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018650 · Cited by 50

PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle

Creyghton, M. P., Roël, G., Eichhorn, P. J. A., Vredeveld, L. C. W., Destrée, O., & Bernards, R. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507237103 · Cited by 46

Identification of Transmembrane Protein 88 (TMEM88) as a Dishevelled-binding Protein

Lee, H., Finkelstein, D., Li, X., Wu, D., Shi, D., & Zheng, J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.193383 · Cited by 45

Involvement of p114-RhoGEF and Lfc in Wnt-3a– and Dishevelled-Induced RhoA Activation and Neurite Retraction in N1E-115 Mouse Neuroblastoma Cells

Tsuji, T., Ohta, Y., Kanno, Y., Hirose, K., Ohashi, K., & Mizuno, K. (2010) · Molecular Biology of the Cell · doi:10.1091/mbc.e10-02-0095 · Cited by 45

The DIX Domain Protein Coiled-coil-DIX1 Inhibits c-Jun N-terminal Kinase Activation by Axin and Dishevelled through Distinct Mechanisms

Wong, C. K., Luo, W., Deng, Y., Zou, H., Ye, Z., & Lin, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m404598200 · Cited by 44

Signaling pathways and preimplantation development of mammalian embryos

Zhang, Y., Yang, Z., & Wu, J. (2007) · FEBS Journal · doi:10.1111/j.1742-4658.2007.05980.x · Cited by 45

YAP promotes neural crest emigration through interactions with BMP and Wnt activities

Kumar, D., Nitzan, E., & Kalcheim, C. (2019) · Cell Communication and Signaling · doi:10.1186/s12964-019-0383-x · Cited by 43

Naked2 Acts as a Cargo Recognition and Targeting Protein to Ensure Proper Delivery and Fusion of TGF-α–containing Exocytic Vesicles at the Lower Lateral Membrane of Polarized MDCK Cells

Li, C., Hao, M., Cao, Z., Ding, W., Graves‐Deal, R., Hu, J., Piston, D. W., & Coffey, R. J. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-02-0172 · Cited by 43

Inhibition of endocytosis blocks Wnt signalling to β‐catenin by promoting dishevelled degradation

Bryja, V., Čajánek, L., Grahn, A., & Schulte, G. (2007) · Acta Physiologica · doi:10.1111/j.1365-201x.2007.01688.x · Cited by 43

Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling

Na, J., Lykke‐Hartmann, K., Torres-Padilla, M. E., & Zernicka‐Goetz, M. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.08.036 · Cited by 42

Wnt Signaling: Role in Regulation of Haematopoiesis

Undi, R. B., Gutti, U., Sahu, I., Sarvothaman, S., Pasupuleti, S. R., Kandi, R., & Gutti, R. K. (2015) · Indian Journal of Hematology and Blood Transfusion · doi:10.1007/s12288-015-0585-3 · Cited by 41

Regulation of Wnt Signalling by Receptor-mediated Endocytosis

Kikuchi, A., & Yamamoto, H. (2007) · The Journal of Biochemistry · doi:10.1093/jb/mvm061 · Cited by 43

Two Frodo/Dapper homologs are expressed in the developing brain and mesoderm of zebrafish

Gillhouse, M., Nyholm, M. K., Hikasa, H., Sokol, S. Y., & Grinblat, Y. (2004) · Developmental Dynamics · doi:10.1002/dvdy.20060 · Cited by 41

Armadillo/β-catenin-dependent Wnt signalling is required for the polarisation of epidermal cells during dorsal closure inDrosophila

Morel, V., & Arias, A. M. (2004) · Development · doi:10.1242/dev.01217 · Cited by 41

Dishevelled: a protein that functions in living cells by phase separating

Sear, R. P. (2007) · Soft Matter · doi:10.1039/b618126k · Cited by 40

MOM-5 Frizzled regulates the distribution of DSH-2 to control C. elegans asymmetric neuroblast divisions

Hawkins, N., Ellis, G. C., Bowerman, B. A., & Garriga, G. (2005) · Developmental Biology · doi:10.1016/j.ydbio.2005.05.024 · Cited by 40

Analysis of dishevelled localization and function in the early sea urchin embryo

Leonard, J. D., & Ettensohn, C. A. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.02.041 · Cited by 41

Viable Mice with Compound Mutations in the Wnt/Dvl Pathway Antagonists nkd1 and nkd2

Zhang, S. J., Çağatay, T., Amanai, M., Zhang, M., Kline, J., Castrillón, D. H., Ashfaq, R., Öz, O. K., & Wharton, K. A. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00133-07 · Cited by 40

Identification of Wnt responsive genes using a murine mammary epithelial cell line model system

Taneyhill, L. A., & Pennica, D. (2004) · BMC Developmental Biology · doi:10.1186/1471-213x-4-6 · Cited by 39

Modulation of the β-Catenin Signaling Pathway by the Dishevelled-Associated Protein Hipk1

Louie, S. H., Yang, X. Y., Conrad, W. H., Muster, J., Angers, S., Moon, R. T., & Cheyette, B. N. R. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004310 · Cited by 38

ROS-Influenced Regulatory Cross-Talk With Wnt Signaling Pathway During Perinatal Development

Chatterjee, S., & Sil, P. C. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.889719 · Cited by 37

Expression of Wnt pathway components frizzled and disheveled in colon cancer arising in patients with inflammatory bowel disease

You, X., Bryant, P., JURNAK, F. A., & Holcombe, R. F. (2007) · Oncology Reports · doi:10.3892/or.18.3.691 · Cited by 35

Downregulation of HDPR1 is associated with poor prognosis and affects expression levels of p120‐catenin and β‐catenin in nonsmall cell lung cancer

Yang, Z., Zhao, Y., Liu, Y., Zhang, J., Zhang, S., Jiang, G., Zhang, P., Yang, L., Liu, D., Li, Q., et al. (2010) · Molecular Carcinogenesis · doi:10.1002/mc.20622 · Cited by 35

Domain Architecture Comparison for Multidomain Homology Identification

Song, N., Sedgewick, R. D., & Durand, D. (2007) · Journal of Computational Biology · doi:10.1089/cmb.2007.a009 · Cited by 35

NEDD4L regulates convergent extension movements in Xenopus embryos via Disheveled-mediated non-canonical Wnt signaling

Zhang, Y., Ding, Y., Chen, Y., & Tao, Q. (2014) · Developmental Biology · doi:10.1016/j.ydbio.2014.05.003 · Cited by 32

Manipulation of glycogen-synthase kinase-3 activity in KSHV-associated cancers

Fujimuro, M., & Hayward, S. D. (2004) · Journal of Molecular Medicine · doi:10.1007/s00109-003-0519-7 · Cited by 33

DEPDC1B knockdown inhibits the development of malignant melanoma through suppressing cell proliferation and inducing cell apoptosis

Xu, Y., Sun, W., Zheng, B., Liu, X. Z., Luo, Z., Kong, Y., Xu, M., & Chen, Y. (2019) · Experimental Cell Research · doi:10.1016/j.yexcr.2019.03.021 · Cited by 31

Protease-activated Receptor-1 (PAR1) Acts via a Novel Gα13-Dishevelled Axis to Stabilize β-Catenin Levels

Turm, H., Maoz, M., Katz, V., Yin, Y., Offermanns, S., & Bar‐Shavit, R. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.072843 · Cited by 31

Dishevelled nuclear shuttling.

Weitzman, J. B. (2005) · Journal of Biology · doi:10.1186/jbiol21 · Cited by 29

Mechanisms of Cytoplasmic β-Catenin Accumulation and Its Involvement in Tumorigenic Activities Mediated by Oncogenic Splicing Variant of the Receptor Originated from Nantes Tyrosine Kinase

Xu, X.-M., Zhou, Y.-Q., & Wang, M. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m414699200 · Cited by 30

Wnt5a signaling controls cytokinesis by positioning ESCRT-III to the proper site at the midbody

Fumoto, K., Kikuchi, K., Gon, H., & Kikuchi, A. (2012) · Journal of Cell Science · doi:10.1242/jcs.108142 · Cited by 29

Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/β-catenin signaling

Swain, R. K., Katoh, M., Medina, A., & Steinbeißer, H. (2005) · Cell Communication and Signaling · doi:10.1186/1478-811x-3-12 · Cited by 29

Dishevelled promotes neurite outgrowth in neuronal differentiating neuroblastoma 2A cells, via a DIX-domain dependent pathway

Fan, S., Ramirez, S. H., Garcia, T. M., & Dewhurst, S. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.09.003 · Cited by 29

Structure and dynamics of the human pleckstrin DEP domain: Distinct molecular features of a novel DEP domain subfamily

Civera, C., Simon, B., Stier, G., Sattler, M., & Macías, M. J. (2004) · Proteins Structure Function and Bioinformatics · doi:10.1002/prot.20320 · Cited by 29

Wingless modulates the ligand independent traffic of Notch through Dishevelled

Descalzo, S. M., Sanders, P., Montagne, C., Johnson, R. I., Balayo, T., & Arias, A. M. (2010) · Fly · doi:10.4161/fly.4.3.11998 · Cited by 28

Potential cross-talk between (pro)renin receptors and Wnt/frizzled receptors in cardiovascular and renal disorders

Balakumar, P., & Jagadeesh, G. (2011) · Hypertension Research · doi:10.1038/hr.2011.113 · Cited by 30

Dishevelled interacts with p65 and acts as a repressor of NF-κB-mediated transcription

Deng, N., Ye, Y., Wang, W., & Li, L. (2010) · Cell Research · doi:10.1038/cr.2010.108 · Cited by 28

Novel Daple-like protein positively regulates both the Wnt/β-catenin pathway and the Wnt/JNK pathway in Xenopus

Kobayashi, H. H., Michiue, T., Yukita, A., Danno, H., Sakurai, K., Fukui, A., Kikuchi, A., & Asashima, M. (2005) · Mechanisms of Development · doi:10.1016/j.mod.2005.05.003 · Cited by 27

Wnt5a signaling promotes apical and basolateral polarization of single epithelial cells

Gon, H., Fumoto, K., Ku, Y., Matsumoto, S., & Kikuchi, A. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-07-0357 · Cited by 28

Loss of 1p36, gain of 8q24, and loss of 9q34 are associated with stroma percentage of colorectal cancer

Fijneman, R. J. A., Carvalho, B. G., Postma, C., Mongera, S., van Hinsbergh, V. W. M., & Meijer, G. A. (2007) · Cancer Letters · doi:10.1016/j.canlet.2007.09.013 · Cited by 28

Activation of Rho and Rac by Wnt/Frizzled Signaling

Habas, R., & He, X. (2006) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(06)06038-1 · Cited by 27

Blocking Dishevelled signaling in the noncanonical Wnt pathway in sea urchins disrupts endoderm formation and spiculogenesis, but not secondary mesoderm formation

Byrum, C. A., Xu, R., Bince, J. M., McClay, D. R., & Wikramanayake, A. H. (2009) · Developmental Dynamics · doi:10.1002/dvdy.21978 · Cited by 30

The Mitogen-Activated Protein Kinase Kinase Kinase Kinase GCKR Positively Regulates Canonical and Noncanonical Wnt Signaling in B Lymphocytes

Shi, C.-S., Huang, N., Harrison, K., Han, S., & Kehrl, J. H. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00209-06 · Cited by 27

Dpr Acts as a Molecular Switch, Inhibiting Wnt Signaling when Unphosphorylated, but Promoting Wnt Signaling when Phosphorylated by Casein Kinase Iδ/ε

Teran, E., Branscomb, A. D., & Seeling, J. M. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005522 · Cited by 27

Disruption of the Dapper3 Gene Aggravates Ureteral Obstruction-mediated Renal Fibrosis by Amplifying Wnt/β-catenin Signaling

Xue, H., Xiao, Z., Zhang, J., Wen, J., Wang, Y., Chang, Z., Zhao, J., Gao, X., Du, J., & Chen, Y. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.458448 · Cited by 28

Dvl regulates endo‐ and exocytotic processes through binding to synaptotagmin

Kishida, S., Hamao, K., Inoue, M., Hasegawa, M., Matsuura, Y., Mikoshiba, K., Fukuda, M., & Kikuchi, A. (2006) · Genes to Cells · doi:10.1111/j.1365-2443.2006.01030.x · Cited by 28

Association of DVL2 and AXIN2 gene polymorphisms with cleft lip with or without cleft palate in a polish population

Mostowska, A., Hozyasz, K. K., Wójcicki, P., Lasota, A., Dunin‐Wilczyńska, I., & Jagodziński, P. P. (2012) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.23056 · Cited by 29

Identification and differential expression of multiple isoforms of mouse Coiled-coil-DIX1 (Ccd1), a positive regulator of Wnt signaling

Shiomi, K., Kanemoto, M., Keino‐Masu, K., Yoshida, S., Soma, K., & Masu, M. (2005) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.12.002 · Cited by 26

Wnt Signaling in Stem Cells and Lung Cancer

He, B., & Jablons, D. M. (2007) · Springer eBooks · doi:10.1007/2789_2007_043 · Cited by 26

Influence of Cell Polarity on Early Development of the Sea Urchin Embryo

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DSH-2 regulates asymmetric cell division in the early C. elegans somatic gonad

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Wnt-dependent assembly of supermolecular Dishevelled-3-based complexes

Yokoyama, N. N., Golebiewska, U. P., Wang, H., & Malbon, C. C. (2010) · Journal of Cell Science · doi:10.1242/jcs.075275 · Cited by 25

Polarity proteins are required for left-right axis orientation and twin-twin instruction

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Wnt Signaling in the Early Sea Urchin Embryo

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RhoA Controls Wnt Upregulation on Microstructured Titanium Surfaces

Lumetti, S., Mazzotta, S., Ferrillo, S., Piergianni, M., Piemontese, M., Passeri, G., Macaluso, G. M., & Galli, C. (2014) · BioMed Research International · doi:10.1155/2014/401859 · Cited by 25

An Unconventional Nuclear Localization Motif Is Crucial for Function of the Drosophila Wnt/Wingless Antagonist Naked Cuticle

Waldrop, S., Chan, C., Çağatay, T., Zhang, S., Rousset, R., Mack, J., Zeng, W., Fish, M., Zhang, M., Amanai, M., et al. (2006) · Genetics · doi:10.1534/genetics.106.061853 · Cited by 26

Structural and Functional Insights into Dishevelled-Mediated Wnt Signaling

Wang, L., Zhu, R., Wen, Z., Fan, H., Norwood-Jackson, T., Jathan, D., & Lee, H. (2024) · Cells · doi:10.3390/cells13221870 · Cited by 23

Origin and Evolution of Dishevelled

Dillman, A. R., Minor, P. J., & Sternberg, P. W. (2013) · G3 Genes Genomes Genetics · doi:10.1534/g3.112.005314 · Cited by 23

The Wnt and BMP Families of Signaling Morphogens at the Vertebrate Neuromuscular Junction

Henríquez, J. P., Krull, C. E., & Osses, N. (2011) · International Journal of Molecular Sciences · doi:10.3390/ijms12128924 · Cited by 23

Targeting the Wnt Pathway in Cancer

Goss, K. H., & Kahn, M. R. (2011) · Springer eBooks · doi:10.1007/978-1-4419-8023-6 · Cited by 23

Regulator of G Protein Signaling 3 Modulates Wnt5b Calcium Dynamics and Somite Patterning

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The N- or C-terminal domains of DSH-2 can activate the C. elegans Wnt/β-catenin asymmetry pathway

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Alterations of Wnt/β-catenin signaling pathway in hepatocellular carcinomas associated with hepatitis C virus

Rogacki, K., Kasprzak, A., & Stępiński, A. (2015) · Polish Journal of Pathology · doi:10.5114/pjp.2015.51148 · Cited by 22

The Dishevelled Protein Family

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Dishevelled: The hub of Wnt signaling

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Wnt signalling sees spots

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Proteomic Analysis of Wnt-Dependent Dishevelled-Based Supermolecular Complexes

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Dishevelled: A masterful conductor of complex Wnt signals

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