Runnin' with the Dvl: Proteins That Associate with Dsh/Dvl and Their Significance to Wnt Signal Transduction

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Morin, P. J., Sparks, A. B., Kořínek, V., Barker, N., Clevers, H. C., Vogelstein, B., & Kinzler, K. W. (1997) · Science · doi:10.1126/science.275.5307.1787 · Cited by 4,000

Wnt signaling and cancer

Polakis, P. (2000) · Genes & Development · doi:10.1101/gad.14.15.1837 · Cited by 3,183

β‐catenin is a target for the ubiquitin–proteasome pathway

Aberle, H., Bauer, A., Stappert, J., Kispert, A., & Kemler, R. (1997) · The EMBO Journal · doi:10.1093/emboj/16.13.3797 · Cited by 2,586

Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism

Liu, C., Li, Y., Semënov, M. V., Han, C., Baeg, G., Tan, Y., Zhang, Z., Lin, X., & He, X. (2002) · Cell · doi:10.1016/s0092-8674(02)00685-2 · Cited by 2,152

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

N�sslein-Volhard, C., Wieschaus, E. F., & Kluding, H. (1984) · Development Genes and Evolution · doi:10.1007/bf00848156 · Cited by 1,552

A new member of the frizzled family from Drosophila functions as a Wingless receptor

Bhanot, P., van den Brink, M. R. M., Samos, C. H., Hsieh, J.-C., Wang, Y., Macke, J. P., Andrew, D. J., Nathans, J., & Nusse, R. (1996) · Nature · doi:10.1038/382225a0 · Cited by 1,504

Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly

Rubinfeld, B., Albert, I., Porfiri, E., Fiol, C. J., Munemitsu, S. M., & Polakis, P. G. (1996) · Science · doi:10.1126/science.272.5264.1023 · Cited by 1,420

Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β

Behrens, J., Jerchow, B., Würtele, M., Grimm, J., Asbrand, C., Wirtz, R. M., Kühl, M., Wedlich, D., & Birchmeier, W. (1998) · Science · doi:10.1126/science.280.5363.596 · Cited by 1,255

Wnt Signaling in Oncogenesis and Embryogenesis--a Look Outside the Nucleus

Peifer, M., & Polakis, P. (2000) · Science · doi:10.1126/science.287.5458.1606 · Cited by 1,253

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK‐3β and β‐catenin and promotes GSK‐3β‐dependent phosphorylation of β‐catenin

Ikeda, S., Kishida, S., Yamamoto, H., Murai, H., Koyama, S., & Kikuchi, A. (1998) · The EMBO Journal · doi:10.1093/emboj/17.5.1371 · Cited by 1,248

Wnt signal transduction pathways

Komiya, Y., & Habas, R. (2008) · Organogenesis · doi:10.4161/org.4.2.5851 · Cited by 1,528

LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling:Arrows point the way

He, X., Semenov, M., Tamai, K., & Zeng, X. (2004) · Development · doi:10.1242/dev.01117 · Cited by 1,044

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

Simons, M., Gloy, J., Ganner, A., Bullerkotte, A., Bashkurov, M., Krönig, C., Schermer, B., Benzing, T., Cabello, O. A., Jenny, A., et al. (2005) · Nature Genetics · doi:10.1038/ng1552 · Cited by 767

Dishevelled: The hub of Wnt signaling

Gao, C., & Chen, Y. (2009) · Cellular Signalling · doi:10.1016/j.cellsig.2009.11.021 · Cited by 780

Wnt and calcium signaling: β-Catenin-independent pathways

Kohn, A. D., & Moon, R. T. (2005) · Cell Calcium · doi:10.1016/j.ceca.2005.06.022 · Cited by 730

WNTS in the vertebrate nervous system: from patterning to neuronal connectivity

Ciani, L., & Salinas, P. C. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1665 · Cited by 543

β-Catenin destruction complex: insights and questions from a structural perspective

Kimelman, D., & Xu, W. (2006) · Oncogene · doi:10.1038/sj.onc.1210055 · Cited by 628

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

Sawamiphak, S., Seidel, S., Essmann, C. L., Wilkinson, G. A., Pitulescu, M. E., Acker, T., & Acker‐Palmer, A. (2010) · Nature · doi:10.1038/nature08995 · Cited by 551

Direct Binding of the PDZ Domain of Dishevelled to a Conserved Internal Sequence in the C-Terminal Region of Frizzled

Wong, H.-C., Bourdelas, A., Krauss, A., Lee, H., Shao, Y., Wu, D., Mlodzik, M., Shi, D., & Zheng, J. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00427-1 · Cited by 551

The Wnt signaling pathway and its role in tumor development

Lustig, B., & Behrens, J. (2003) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-003-0431-0 · Cited by 525

The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity

Wallingford, J. B., & Habas, R. (2005) · Development · doi:10.1242/dev.02068 · Cited by 509

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions

Zeng, X., Huang, H., Tamai, K., Zhang, X., Harada, Y., Yokota, C., Almeida, K., Wang, J., Doble, B., Woodgett, J., et al. (2008) · Development · doi:10.1242/dev.013540 · Cited by 492

Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

Gao, C., Cao, W., Bao, L., Zuo, W., Xie, G., Cai, T., Fu, W., Zhang, J., Wu, W., Zhang, X., et al. (2010) · Nature Cell Biology · doi:10.1038/ncb2082 · Cited by 393

The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation

Angers, S., Thorpe, C. J., Biechele, T. L., Goldenberg, S. J., Zheng, N., MacCoss, M. J., & Moon, R. T. (2006) · Nature Cell Biology · doi:10.1038/ncb1381 · Cited by 364

Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos

Sheldahl, L. C., Slusarski, D. C., Pandur, P., Miller, J. R., Kühl, M., & Moon, R. T. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200211094 · Cited by 350

Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression

Uematsu, K., He, B., You, L., Xu, Z., McCormick, F. P., & Jablons, D. M. (2003) · Oncogene · doi:10.1038/sj.onc.1206817 · Cited by 317

Wnt/Notch signalling and information processing during development

Hayward, P. C., Kalmár, T., & Arias, A. M. (2008) · Development · doi:10.1242/dev.000505 · Cited by 299

Multiplicity of the interactions of Wnt proteins and their receptors

Kikuchi, A., Yamamoto, H., & Kishida, S. (2006) · Cellular Signalling · doi:10.1016/j.cellsig.2006.11.001 · Cited by 289

The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis

Rivkin, E., Almeida, S. M., Ceccarelli, D. F. J., Juang, Y.-C. A., MacLean, T. A., Srikumar, T., Huang, H., Dunham, W. H., Fukumura, R., ., G. X., et al. (2013) · Nature · doi:10.1038/nature12296 · Cited by 288

New Insights into the Mechanism of Wnt Signaling Pathway Activation

Kikuchi, A., Yamamoto, H., Sato, A., & Matsumoto, S. (2011) · International review of cytology · doi:10.1016/b978-0-12-386035-4.00002-1 · Cited by 275

Wnt signaling in lung cancer

Mazières, J., He, B., You, L., Xu, Z., & Jablons, D. M. (2005) · Cancer Letters · doi:10.1016/j.canlet.2004.08.040 · Cited by 248

Maternal factors in zebrafish development

Pelegri, F. J. (2003) · Developmental Dynamics · doi:10.1002/dvdy.10390 · Cited by 248

An Antagonist of Dishevelled Protein-Protein Interaction Suppresses β-Catenin–Dependent Tumor Cell Growth

Fujii, N., You, L., Xu, Z., Uematsu, K., Shan, J., He, B., Mikami, I., Edmondson, L. R., Neale, G. A. M., Zheng, J., et al. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-2726 · Cited by 237

Dynamic recruitment of axin by Dishevelled protein assemblies

Schwarz, T., Metcalfe, C., & Bienz, M. (2007) · Journal of Cell Science · doi:10.1242/jcs.002956 · Cited by 225

Dishevelled: A masterful conductor of complex Wnt signals

Sharma, M., Castro‐Piedras, I., Simmons, G. E., Jr., & Pruitt, K. (2018) · Cellular Signalling · doi:10.1016/j.cellsig.2018.03.004 · Cited by 224

Wnt/beta-Catenin Signaling and Small Molecule Inhibitors

Voronkov, A. E., & Krauss, S. J. K. (2012) · Current Pharmaceutical Design · doi:10.2174/138161213804581837 · Cited by 227

The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles

Schwarz, T., Merrifield, C. J., Nichols, B. J., & Bienz, M. (2005) · Journal of Cell Science · doi:10.1242/jcs.02646 · Cited by 214

Dishevelled and Wnt signaling: is the nucleus the final frontier?

Habas, R., & Dawid, I. B. (2005) · Journal of Biology · doi:10.1186/jbiol22 · Cited by 219

Canonical Wnt activity regulates trunk neural crest delamination linking BMP/noggin signaling with G1/S transition

Burstyn‐Cohen, T., Stanleigh, J., Sela‐Donenfeld, D., & Kalcheim, C. (2004) · Development · doi:10.1242/dev.01424 · Cited by 207

RNA Helicase DDX3 Is a Regulatory Subunit of Casein Kinase 1 in Wnt–β-Catenin Signaling

Cruciat, C., Dolde, C. E., de Groot, R. E. A., Ohkawara, B., Reinhard, C., Korswagen, H. C., & Niehrs, C. (2013) · Science · doi:10.1126/science.1231499 · Cited by 213

Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex

Foley, A. C., & Mercola, M. (2005) · Genes & Development · doi:10.1101/gad.1279405 · Cited by 195

NONCANONICAL WNT SIGNALING AND NEURAL POLARITY

Montcouquiol, M., Crenshaw, E. B., & Kelley, M. W. (2006) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112933 · Cited by 197

The Wnt connection to tumorigenesis

Behrens, J., & Lustig, B. (2004) · The International Journal of Developmental Biology · doi:10.1387/ijdb.041815jb · Cited by 200

Dishevelled Promotes Wnt Receptor Degradation through Recruitment of ZNRF3/RNF43 E3 Ubiquitin Ligases

Jiang, X., Charlat, O., Zamponi, R., Yang, Y., & Cong, F. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.03.015 · Cited by 199

Activation of the Canonical Wingless/T-Cell Factor Signaling Pathway Promotes Invasive Differentiation of Human Trophoblast

Pollheimer, J., Loregger, T., Sonderegger, S., Saleh, L., Bauer, S., Bilban, M., Czerwenka, K. F., Husslein, P. W., & Knöfler, M. (2006) · American Journal Of Pathology · doi:10.2353/ajpath.2006.050686 · Cited by 191

DEP-Domain-Mediated Regulation of GPCR Signaling Responses

Ballon, D. R., Flanary, P. L., Gladue, D. P., Konopka, J. B., Dohlman, H. G., & Thorner, J. W. (2006) · Cell · doi:10.1016/j.cell.2006.07.030 · Cited by 189

Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism

Bryja, V., Schulte, G., Rawal, N., Grahn, A., & Arenas, E. (2007) · Journal of Cell Science · doi:10.1242/jcs.03368 · Cited by 186

Wnt Proteins Induce Dishevelled Phosphorylation via an LRP5/6- Independent Mechanism, Irrespective of Their Ability To Stabilize β-Catenin

González‐Sancho, J. M., Brennan, K. R., Castelo‐Soccio, L. A., & Brown, A. M. C. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.11.4757-4768.2004 · Cited by 184

Evolution of the Wnt Pathways

Croce, J. C., & McClay, D. R. (2008) · Methods in molecular biology · doi:10.1007/978-1-60327-469-2_1 · Cited by 186

NEDL1, a Novel Ubiquitin-protein Isopeptide Ligase for Dishevelled-1, Targets Mutant Superoxide Dismutase-1

Miyazaki, K., Fujita, T., Ozaki, T., Kato, C., Kurose, Y., Sakamoto, M., Kato, S., Goto, T., Itoyama, Y., Aoki, M., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312389200 · Cited by 177

PKCδ is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movementsPreprint

Kinoshita, N., Iioka, H., Miyakoshi, A., & Ueno, N. (2003) · Genes & Development · doi:10.1101/gad.1101303 · Cited by 176

Noncanonical Wnt signaling regulates midline convergence of organ primordia during zebrafish developmentPreprint

Matsui, T., Raya, Á., Kawakami, Y., Callol-Massot, C., Capdevila, J., Rodrı́guez-Esteban, C., & Belmonte, J. C. I. (2005) · Genes & Development · doi:10.1101/gad.1253605 · Cited by 164

Inhibition of Wnt signaling by Dishevelled PDZ peptides

Zhang, Y., Appleton, B. A., Wiesmann, C., Lau, T., Costa, M., Hannoush, R. N., & Sidhu, S. S. (2009) · Nature Chemical Biology · doi:10.1038/nchembio.152 · Cited by 163

Dapper 1 Antagonizes Wnt Signaling by Promoting Dishevelled Degradation

Zhang, L., Gao, X., Wen, J., Ning, Y., & Chen, Y. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600274200 · Cited by 157

The role of the Wnt signalling pathway in colorectal tumorigenesis

Behrens, J. (2005) · Biochemical Society Transactions · doi:10.1042/bst0330672 · Cited by 160

Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK

Unterseher, F., Hefele, J. A., Giehl, K., Robertis, E. M. D., Wedlich, D., & Schambony, A. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600332 · Cited by 152

Winding through the WNT pathway during cellular development and demise.

Li, F., Chong, Z. Z., & Maiese, K. (2006) · PubMed · doi:10.14670/hh-21.103 · Cited by 154

Multiple Wnt Signaling Pathways Converge to Orient the Mitotic Spindle in Early C. elegans Embryos

Walston, T., Tuskey, C., Edgar, L. G., Hawkins, N., Ellis, G. C., Bowerman, B. A., Wood, W. B., & Hardin, J. D. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.10.008 · Cited by 144

Differential stability of β-catenin along the animal-vegetal axis of the sea urchin embryo mediated by dishevelled

Weitzel, H. E., Illies, M. R., Byrum, C. A., Xu, R., Wikramanayake, A. H., & Ettensohn, C. A. (2004) · Development · doi:10.1242/dev.01152 · Cited by 141

Prickle-1 Negatively Regulates Wnt/β-Catenin Pathway by Promoting Dishevelled Ubiquitination/Degradation in Liver Cancer

Chan, D. W., Chan, C., Yam, J. W. P., Ching, Y., & Ng, I. O. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.07.020 · Cited by 135

β-Arrestin is a necessary component of Wnt/β-catenin signaling in vitro and in vivo

Bryja, V., Gradl, D., Schambony, A., Arenas, E., & Schulte, G. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611356104 · Cited by 139

Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3

Lee, Y.-N., Gao, Y., & Wang, H. (2007) · Cellular Signalling · doi:10.1016/j.cellsig.2007.11.005 · Cited by 133

Wnts induce migration and invasion of myeloma plasma cells

Qiang, Y. (2005) · Blood · doi:10.1182/blood-2005-01-0049 · Cited by 133

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

Hocevar, B. A., Mou, F., Rennolds, J. L., Morris, S. M., Cooper, J. A., & Howe, P. H. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg286 · Cited by 117

The β-Catenin/T-Cell Factor/Lymphocyte Enhancer Factor Signaling Pathway Is Required for Normal and Stress-Induced Cardiac Hypertrophy

Chen, X., Shevtsov, S. P., Hsich, E., Cui, L., Haq, S., Aronovitz, M. J., Kerkelä, R., Molkentin, J. D., Liao, R., Salomon, R., et al. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.02157-05 · Cited by 132

Wnt signaling promotes AChR aggregation at the neuromuscular synapse in collaboration with agrin

Henríquez, J. P., Webb, A., Bence, M., Bildsoe, H., Sahores, M., Hughes, S. M., & Salinas, P. C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0806300105 · Cited by 136

Wnt signaling activation during bone regeneration and the role of Dishevelled in chondrocyte proliferation and differentiation

Zhong, N., Gersch, R. P., & Hadjiargyrou, M. (2006) · Bone · doi:10.1016/j.bone.2005.12.008 · Cited by 129

Wnt-3a and Dvl Induce Neurite Retraction by Activating Rho-Associated Kinase

Kishida, S., Yamamoto, H., & Kikuchi, A. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.10.4487-4501.2004 · Cited by 128

Osteocytes and WNT: the Mechanical Control of Bone Formation

Galli, C., Passeri, G., & Macaluso, G. M. (2010) · Journal of Dental Research · doi:10.1177/0022034510363963 · Cited by 136

The canonical Wnt pathway in early mammalian embryogenesis and stem cell maintenance/differentiation

Wang, J., & Wynshaw-Boris, A. J. (2004) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2004.07.013 · Cited by 125

Binding of APC and dishevelled mediates Wnt5a‐regulated focal adhesion dynamics in migrating cells

Matsumoto, S., Fumoto, K., Okamoto, T., Kaibuchi, K., & Kikuchi, A. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.26 · Cited by 120

Transcriptional Profiling of the Heart Reveals Chamber-Specific Gene Expression Patterns

Tabibiazar, R., Wagner, R. A., Liao, A. K., & Quertermous, T. (2003) · Circulation Research · doi:10.1161/01.res.0000103171.42654.dd · Cited by 116

Tumor formation due to abnormalities in the β‐catenin‐independent pathway of Wnt signaling

Kikuchi, A., & Yamamoto, H. (2008) · Cancer Science · doi:10.1111/j.1349-7006.2007.00675.x · Cited by 117

Interruption of Wnt Signaling Attenuates the Onset of Pressure Overload-Induced Cardiac Hypertrophy

van de Schans, V. A. M., van den Borne, S. W. M., Strzelecka‐Kiliszek, A., Janssen, B. J., van der Velden, J. L. J., LANGEN, R. C. J., Boris, A. W., Smits, J. F. M., & Blankesteijn, W. M. (2007) · Hypertension · doi:10.1161/01.hyp.0000255946.55091.24 · Cited by 114

SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling

Holloway, K. R., Calhoun, T. N., Saxena, M., Metoyer, C. F., Kandler, E. F., Rivera, C. A., & Pruitt, K. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911325107 · Cited by 115

Distinct PAR-1 Proteins Function in Different Branches of Wnt Signaling during Vertebrate Development

Ossipova, O., Dhawan, S., Sokol, S., & Green, J. B. A. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.04.011 · Cited by 113

The many roles of PTK7: A versatile regulator of cell–cell communication

Peradziryi, H., Tolwinski, N. S., & Borchers, A. (2012) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2011.12.019 · Cited by 117

Sequential Activation and Inactivation of Dishevelled in the Wnt/β-Catenin Pathway by Casein Kinases

Bernatík, O., Ganji, R. S., Dijksterhuis, J. P., Koník, P., Červenka, I., Polonio, T., Krejčı́, P., Schulte, G., & Bryja, V. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.169870 · Cited by 109

Nucleoredoxin, a Novel Thioredoxin Family Member Involved in Cell Growth and Differentiation

Funato, Y., & Miki, H. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1550 · Cited by 117

Wnt Signaling: Physiology and Pathology

Prunier, C., Hocevar, B. A., & Howe, P. H. (2004) · Growth Factors · doi:10.1080/08977190410001720860 · Cited by 109

Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis

Li, Y., Zhang, H., Choi, S. C., Litingtung, Y., & Chiang, C. C. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.03.009 · Cited by 108

Inhibition of the Wnt/β-catenin pathway by the WWOX tumor suppressor protein

Bouteille, N. K., Driouch, K., Hage, P. E., Sin, S., Formstecher, É., Camonis, J., Lidereau, R., & Lallemand, F. (2009) · Oncogene · doi:10.1038/onc.2009.120 · Cited by 106

JNK and ROKα function in the noncanonical Wnt/RhoA signaling pathway to regulate Xenopus convergent extension movements

Kim, G., & Han, J. (2005) · Developmental Dynamics · doi:10.1002/dvdy.20262 · Cited by 105

Dishevelled: A Mobile Scaffold Catalyzing Development

Malbon, C. C., & Wang, H. (2005) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(05)72002-0 · Cited by 107

Dishevelled 2 Signaling Promotes Self-Renewal and Tumorigenicity in Human Gliomas

Pulvirenti, T., van der Heijden, M., Droms, L. A., Huse, J. T., Tabar, V. S., & Hall, A. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-1531 · Cited by 103

Canonical Wnt Signaling is Necessary for Object Recognition Memory Consolidation

Fortress, A. M., Schram, S., Tuscher, J. J., & Frick, K. M. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0659-13.2013 · Cited by 105

LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse

Sakane, H., Yamamoto, H., & Kikuchi, A. (2010) · Journal of Cell Science · doi:10.1242/jcs.058008 · Cited by 99

Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling

Sakane, H., Yamamoto, H., Matsumoto, S., Sato, A., & Kikuchi, A. (2012) · Journal of Cell Science · doi:10.1242/jcs.091876 · Cited by 97

The various roles of ubiquitin in Wnt pathway regulation

Tauriello, D. V. F., & Maurice, M. M. (2010) · Cell Cycle · doi:10.4161/cc.9.18.13204 · Cited by 100

Vital Elements of the Wnt-Frizzled Signaling Pathway in the Nervous System

Li, F., Chong, Z. Z., & Maiese, K. (2005) · Current Neurovascular Research · doi:10.2174/156720205774322557 · Cited by 93

RanBP3 enhances nuclear export of active β-catenin independently of CRM1

Hendriksen, J., Fagotto, F., van der Velde, H., van Schie, M., Noordermeer, J. N., & Fornerod, M. W. J. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200502141 · Cited by 91

Molecular regulation of kidney development: is the answer blowing in the Wnt?

Merkel, C. E., Karner, C. M., & Carroll, T. J. (2007) · Pediatric Nephrology · doi:10.1007/s00467-007-0504-4 · Cited by 91

The ins and outs of Wingless signaling

Seto, E., & Bellen, H. J. (2003) · Trends in Cell Biology · doi:10.1016/j.tcb.2003.11.004 · Cited by 89

The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility

Takagishi, M., Enomoto, A., Asai, N., Ushida, K., Watanabe, T., Hashimoto, T., Kato, T., Weng, L., Matsumoto, S., Asai, M., et al. (2012) · Nature Communications · doi:10.1038/ncomms1861 · Cited by 87

Zebrafish Dapper1 and Dapper2 play distinct roles in Wnt-mediated developmental processes

Waxman, J. S., Hocking, A. M., Stoick-Cooper, C. L., & Moon, R. T. (2004) · Development · doi:10.1242/dev.01520 · Cited by 89

Development of anticancer agents targeting the Wnt/β-catenin signaling.

Zhang, X., & Hao, J. (2015) · Europe PMC (PubMed Central) · Cited by 85

Gαo mediates WNT-JNK signaling through Dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells

Bikkavilli, R. K., Feigin, M. E., & Malbon, C. C. (2008) · Journal of Cell Science · doi:10.1242/jcs.021964 · Cited by 88

Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1

Kikuchi, K., Niikura, Y., Kitagawa, K., & Kikuchi, A. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.221 · Cited by 82

Wnt/Frizzled Signaling during Vertebrate Retinal Development

Raay, T. J. V., & Vetter, M. L. (2004) · Developmental Neuroscience · doi:10.1159/000082277 · Cited by 80

Requirement for intracellular calcium modulation in zebrafish dorsal–ventral patterning

Westfall, T. A., Hjertos, B., & Slusarski, D. C. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00209-4 · Cited by 82

Wnt signaling and neural stem cells: caught in the Wnt web

Michaelidis, T. M., & Lie, D. C. (2007) · Cell and Tissue Research · doi:10.1007/s00441-007-0476-5 · Cited by 84

An analysis of the gene expression program of mammalian neural progenitor cells

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